• 1151 Citations
  • 18 h-Index
20012021
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Research Output 2001 2019

  • 1151 Citations
  • 18 h-Index
  • 21 Article
  • 4 Chapter
  • 1 Review article
  • 1 Patent
2019

Bioprospecting of Native Efflux Pumps To Enhance Furfural Tolerance in Ethanologenic Escherichia coli

Kurgan, G., Panyon, L. A., Rodriguez-Sanchez, Y., Pacheco, E., Nieves, L. M., Mann, R., Nielsen, D. & Wang, X., Mar 15 2019, In : Applied and environmental microbiology. 85, 6

Research output: Contribution to journalArticle

Furaldehyde
furfural
multiple drug resistance
Multiple Drug Resistance
transporters

Engineering a Synthetic, Catabolically Orthogonal Coculture System for Enhanced Conversion of Lignocellulose-Derived Sugars to Ethanol

Flores, A. D., Ayla, E. Z., Nielsen, D. & Wang, X., May 17 2019, In : ACS Synthetic Biology. 8, 5, p. 1089-1099 11 p.

Research output: Contribution to journalArticle

Coculture Techniques
Sugars
Fermentation
Xylose
Ethanol
2017

Amyloid: Friend and foe

Jain, N., Hammer, N. D., Wang, X., McGuffie, B. A. & Chapman, M. R., Mar 10 2017, Handbook of Infection and Alzheimer's Disease. IOS Press, p. 297-311 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Amyloid
Amyloidogenic Proteins
Endopeptidase K
Prion Diseases
Poisons
1 Citation (Scopus)

Amyloid: Friend and Foe

Jain, N., Hammer, N. D., Wang, X., McGuffie, B. A. & Chapman, M. R., 2017, Handbook of Infection and Alzheimer's Disease. IOS Press, Vol. 5. p. 297-311 15 p. (Advances in Alzheimer's Disease; vol. 5).

Research output: Chapter in Book/Report/Conference proceedingChapter

Amyloid
Amyloidogenic Proteins
Endopeptidase K
Prion Diseases
Poisons

Engineering bacterial sugar catabolism and tolerance toward lignocellulose conversion

Flores, A. D., Kurgan, G. L. & Wang, X., Jan 1 2017, Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. Springer International Publishing, p. 147-180 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sugars
Biomass
Biochemical Phenomena
Catabolite Repression
Metabolic Engineering
5 Citations (Scopus)

Experimental evolution reveals an effective avenue to release catabolite repression via mutations in XylR

Sievert, C., Nieves, L. M., Panyon, L. A., Loeffler, T., Morris, C., Cartwright, R., Wang, X. & Demain, A. L., Jul 11 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 28, p. 7349-7354 6 p.

Research output: Contribution to journalArticle

Catabolite Repression
Xylose
Mutation
Escherichia coli
Biomass
2016
1 Citation (Scopus)

Engineering Central Metabolism for Production of Higher Alcohol-based Biofuels

Immethun, C. M., Henson, W. R., Wang, X., Nielsen, D. & Moon, T. S., Jan 20 2016, Biotechnology for Biofuel Production and Optimization. Elsevier Inc., p. 1-34 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biofuels
Metabolism
Alcohols
Bioethanol
Availability
2015
21 Citations (Scopus)

Engineering sugar utilization and microbial tolerance toward lignocellulose conversion

Nieves, L. M., Panyon, L. A. & Wang, X., Jan 1 2015, In : Frontiers in Bioengineering and Biotechnology. 3, FEB, 00017.

Research output: Contribution to journalReview article

Sugars
Fermentation
Biocatalysts
Biological systems
Petrochemicals
xylose
genetic engineering
glucose
feedstocks
bioethanol
2013
104 Citations (Scopus)

Engineering furfural tolerance in Escherichia coli improves the fermentation of lignocellulosic sugars into renewable chemicals

Wang, X., Yomano, L. P., Lee, J. Y., York, S. W., Zheng, H., Mullinnix, M. T., Shanmugam, K. T. & Ingram, L. O., Mar 5 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 10, p. 4021-4026 6 p.

Research output: Contribution to journalArticle

Furaldehyde
Fermentation
Escherichia coli
Succinic Acid
Ethanol
22 Citations (Scopus)

Improving Escherichia coli fucO for furfural tolerance by saturation mutagenesis of individual amino acid positions

Zheng, H., Wang, X., Yomano, L. P., Geddes, R. D., Shanmugam, K. T. & Ingram, L. O., May 2013, In : Applied and Environmental Microbiology. 79, 10, p. 3202-3208 7 p.

Research output: Contribution to journalArticle

Furaldehyde
furfural
mutagenesis
Mutagenesis
amino acid
2012
19 Citations (Scopus)

Increased furan tolerance in Escherichia coli due to a Cryptic ucpA Gene

Wang, X., Miller, E. N., Yomano, L. P., Shanmugam, K. T. & Ingram, L. O., Apr 2012, In : Applied and Environmental Microbiology. 78, 7, p. 2452-2455 4 p.

Research output: Contribution to journalArticle

Furaldehyde
furfural
furan
furans
tolerance
21 Citations (Scopus)

Increase in furfural tolerance in ethanologenic Escherichia coli LY180 by plasmid-based expression of ThyA

Zheng, H., Wang, X., Yomano, L. P., Shanmugam, K. T. & Ingram, L. O., Jun 2012, In : Applied and Environmental Microbiology. 78, 12, p. 4346-4352 7 p.

Research output: Contribution to journalArticle

Furaldehyde
furfural
plasmid
plasmids
Plasmids
2011
57 Citations (Scopus)

Increased furfural tolerance due to overexpression of NADH-dependent oxidoreductase FucO in Escherichia coli strains engineered for the production of ethanol and lactate

Wang, X., Miller, E. N., Yomano, L. P., Zhang, X., Shanmugam, K. T. & Ingram, L. O., Aug 2011, In : Applied and Environmental Microbiology. 77, 15, p. 5132-5140 9 p.

Research output: Contribution to journalArticle

Furaldehyde
furfural
NAD (coenzyme)
oxidoreductases
ethanol production
97 Citations (Scopus)

L-malate production by metabolically engineered Escherichia coli

Zhang, X., Wang, X., Shanmugam, K. T. & Ingram, L. O., Jan 2011, In : Applied and Environmental Microbiology. 77, 2, p. 427-434 8 p.

Research output: Contribution to journalArticle

malates
Escherichia coli
Pyruvic Acid
Fumarate Hydratase
lactates
2010
57 Citations (Scopus)

Gatekeeper residues in the major curlin subunit modulate bacterial amyloid fiber biogenesis

Wang, X., Zhou, Y., Ren, J. J., Hammer, N. D. & Chapman, M. R., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 1, p. 163-168 6 p.

Research output: Contribution to journalArticle

Amyloid
Polymerization
Escherichia coli Proteins
Protein Subunits
Aspartic Acid
102 Citations (Scopus)

Metabolic engineering for production of biorenewable fuels and chemicals: Contributions of synthetic biology

Ingram, L. O., Jarboe, L. R., Zhang, X., Wang, X., Moore, J. C. & Shanmugam, K. T., 2010, In : Journal of Biomedicine and Biotechnology. 2010, 761042.

Research output: Contribution to journalArticle

Synthetic Biology
Metabolic engineering
Metabolic Engineering
Enzymes
Petrochemicals
2008
60 Citations (Scopus)

Amyloids: Friend or foe?

Hammer, N. D., Wang, X., McGuffie, B. A. & Chapman, M. R., 2008, In : Journal of Alzheimer's Disease. 13, 4, p. 407-419 13 p.

Research output: Contribution to journalArticle

Amyloid
Amyloidogenic Proteins
Endopeptidase K
Prion Diseases
Poisons
30 Citations (Scopus)

Curli provide the template for understanding controlled amyloid propagation.

Wang, X. & Chapman, M. R., Apr 2008, In : Prion. 2, 2, p. 57-60 4 p.

Research output: Contribution to journalArticle

Amyloid
Polymerization
Fibers
Escherichia coli Proteins
Asparagine
60 Citations (Scopus)

Sequence Determinants of Bacterial Amyloid Formation

Wang, X. & Chapman, M. R., Jul 11 2008, In : Journal of Molecular Biology. 380, 3, p. 570-580 11 p.

Research output: Contribution to journalArticle

Amyloid
Alanine
Amyloidogenic Proteins
Proteins
Prions
81 Citations (Scopus)

The molecular basis of functional bacterial amyloid polymerization and nucleation

Wang, X., Hammer, N. D. & Chapman, M. R., Aug 1 2008, In : Journal of Biological Chemistry. 283, 31, p. 21530-21539 10 p.

Research output: Contribution to journalArticle

Amyloid
Polymerization
Nucleation
Protein Subunits
Fibers
2007
115 Citations (Scopus)

In vitro polymerization of a functional Escherichia coli amyloid protein

Wang, X., Smith, D. R., Jones, J. W. & Chapman, M. R., Jan 9 2007, In : Journal of Biological Chemistry. 282, 6, p. 3713-3719 7 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Escherichia coli Proteins
Amyloid
Polymerization
Escherichia coli
2006
22 Citations (Scopus)

Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site

Zhang, R., Xiao, W., Wang, X., Wu, X. & Tian, W., Jan 2006, In : Biotechnology and Applied Biochemistry. 43, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Camellia sinensis
Fatty Acid Synthases
Tea
Fatty acids
Inhibitory Concentration 50
2005
32 Citations (Scopus)
Fatty Acid Synthases
Tea
Oral Administration
Rats
Eating
2003
2 Citations (Scopus)

Inhibitive effect of zinc ion on fatty acid synthase from chicken liver

Wang, F., Wang, X., Liu, Y., Tian, W. X. & Zhou, H. M., Mar 1 2003, In : International Journal of Biochemistry and Cell Biology. 35, 3, p. 391-400 10 p.

Research output: Contribution to journalArticle

Malonyl Coenzyme A
Fatty Acid Synthases
Electrophoresis
Liver
Zinc
97 Citations (Scopus)

The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase

Wang, X., Song, K. S., Guo, Q. X. & Tian, W. X., Nov 15 2003, In : Biochemical Pharmacology. 66, 10, p. 2039-2047 9 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Catechin
Tea
Propyl Gallate
Nuclear Energy
2001
145 Citations (Scopus)

Green tea epigallocatechin gallate: A natural inhibitor of fatty-acid synthase

Wang, X. & Tian, W., Nov 16 2001, In : Biochemical and Biophysical Research Communications. 288, 5, p. 1200-1206 7 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Tea
NADP
Cerulenin
Malonyl Coenzyme A