• 1099 Citations
  • 20 h-Index
1980 …2019

Research output per year

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Research Output

2019

Structural asymmetry and kinetic limping of single rotary F-ATP synthases

Sielaff, H., Yanagisawa, S., Frasch, W., Junge, W. & Börsch, M., Jan 30 2019, In : Molecules. 504.

Research output: Contribution to journalReview article

6 Scopus citations
2018

Elastic coupling power stroke mechanism of the F1-ATPase molecular motor

Martin, J. L., Ishmukhametov, R., Spetzler, D., Hornung, T. & Frasch, W., May 29 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. 5750-5755 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Protonation-dependent stepped rotation of the F-type ATP synthase c-ring observed by single-molecule measurements

Yanagisawa, S. & Frasch, W., Oct 13 2017, In : Journal of Biological Chemistry. 292, 41, p. 17093-17100 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation

Ragunathan, P., Sielaff, H., Sundararaman, L., Biuković, G., Manimekalai, M. S. S., Singh, D., Kundu, S., Wohland, T., Frasch, W., Dick, T. & Grüber, G., Jul 7 2017, In : Journal of Biological Chemistry. 292, 27, p. 11262-11279 18 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Power stroke angular velocity profiles of archaeal A-ATP synthase versus thermophilic and mesophilic F-ATP synthase molecular motors

Sielaff, H., Martin, J., Singh, D., Biuković, G., Grüber, G. & Frasch, W., Dec 2 2016, In : Journal of Biological Chemistry. 291, 49, p. 25351-25363 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

F<inf>o</inf>-driven rotation in the ATP synthase direction against the force of F<inf>1</inf> ATPase in the F<inf>o</inf>F<inf>1</inf> ATP lynthase

Martin, J., Hudson, J., Hornung, T. & Frasch, W., Apr 24 2015, In : Journal of Biological Chemistry. 290, 17, p. 10717-10728 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Anatomy of F1-ATPase powered rotation

Martin, J. L., Ishmukhametov, R., Hornung, T., Ahmad, Z. & Frasch, W., Mar 11 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 10, p. 3715-3720 6 p.

Research output: Contribution to journalArticle

53 Scopus citations
2011

Microsecond resolution of single-molecule rotation catalyzed by molecular motors

Hornung, T., Martin, J., Spetzler, D., Ishmukhametov, R. & Frasch, W., Oct 24 2011, Single Molecule Enzymology: Methods and Protocols. Mashanov, G. I. & Batters, C. (eds.). p. 273-289 17 p. (Methods in Molecular Biology; vol. 778).

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Padlock probe-mediated qRT-PCR for DNA computing answer determination

Xiong, F. & Frasch, W., Jun 1 2011, In : Natural Computing. 10, 2, p. 947-959 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2010

Direct observation of stepped proteolipid ring rotation in E. coli F o F 1-ATP synthase

Ishmukhametov, R., Hornung, T., Spetzler, D. & Frasch, W., Dec 1 2010, In : EMBO Journal. 29, 23, p. 3911-3923 13 p.

Research output: Contribution to journalArticle

72 Scopus citations
2009

Single molecule measurements of F1-ATPase reveal an interdependence between the power stroke and the dwell duration

Spetzler, D., Ishmukhametov, R., Hornung, T., Day, L. J., Martin, J. & Frasch, W., Aug 25 2009, In : Biochemistry. 48, 33, p. 7979-7985 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Solving the fully-connected 15-city TSP using probabilistic DNA computing

Xiong, F., Spetzler, D. & Frasch, W., Dec 1 2009, In : Integrative Biology. 1, 3, p. 275-280 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2008

Determination of torque generation from the power stroke of Escherichia coli F1-ATPase

Hornung, T., Ishmukhametov, R., Spetzler, D., Martin, J. & Frasch, W., Jul 1 2008, In : Biochimica et Biophysica Acta - Bioenergetics. 1777, 7-8, p. 579-582 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Heuristic solution to a 10-city asymmetric traveling salesman problem using probabilistic DNA computing

Spetzler, D., Xiong, F. & Frasch, W., Aug 27 2008, DNA Computing - 13th International Meeting on DNA Computing, DNA13, Revised Selected Papers. p. 152-160 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 4848 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Single-molecule detection of DNA via sequence-specific links between F 1-ATPase motors and gold nanorod sensors

York, J., Spetzler, D., Xiong, F. & Frasch, W., Jan 1 2008, In : Lab on a Chip. 8, 3, p. 415-419 5 p.

Research output: Contribution to journalArticle

38 Scopus citations
2007

Abundance of Escherichia coli F1-ATPase molecules observed to rotate via single-molecule microscopy with gold nanorod probes

York, J., Spetzler, D., Hornung, T., Ishmukhametov, R., Martin, J. & Frasch, W., Dec 1 2007, In : Journal of Bioenergetics and Biomembranes. 39, 5-6, p. 435-439 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Recent developments of bio-molecular motors as on-chip devices using single molecule techniques

Spetzler, D., York, J., Dobbin, C., Martin, J., Ishmukhametov, R., Day, L., Yu, J., Kang, H., Porter, K., Hornung, T. & Frasch, W., 2007, In : Lab on a Chip. 7, 12, p. 1633-1643 11 p.

Research output: Contribution to journalReview article

24 Scopus citations
2006
6 Scopus citations

Microsecond time scale rotation measurements of single F1-ATPase molecules

Spetzler, D., York, J., Daniel, D., Fromme, R., Lowry, D. & Frasch, W., Mar 14 2006, In : Biochemistry. 45, 10, p. 3117-3124 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Single Molecule Detection

Frasch, W., Jan 27 2006

Research output: Patent

2005

DNA Computing

Frasch, W., Sep 15 2005

Research output: Patent

15 Scopus citations
8 Scopus citations
2003

Interactions among γR268, γQ269, and the β Subunit Catch Loop of Escherichia coli F1-ATPase Are Important for Catalytic Activity

Greene, M. D. & Frasch, W., Dec 19 2003, In : Journal of Biological Chemistry. 278, 51, p. 51594-51598 5 p.

Research output: Contribution to journalArticle

30 Scopus citations
2002

Molecular Semaphore Device Gold Rods

Frasch, W., Sep 9 2002

Research output: Patent

2001

Identification of the P-loop lysine as a metal ligand in the absence of nucleotide at catalytic site 3 of chloroplast F1-ATPase from Chlamydomonas reinhardtii

Crampton, D. J., Lobrutto, R. & Frasch, W., Mar 27 2001, In : Biochemistry. 40, 12, p. 3710-3716 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interaction of the catch-loop tyrosine βY317 with the metal at catalytic site 3 of Chlamydomonas chloroplast F1-ATPase

Chen, W. & Frasch, W., Jun 26 2001, In : Biochemistry. 40, 25, p. 7729-7735 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2000

Characterization of the metal binding environment of catalytic site 1 of chloroplast F(1)-ATPase from Chlamydomonas

Chen, W., Hu, C. Y., Crampton, D. J. & Frasch, W., Aug 8 2000, In : Biochemistry. 39, 31, p. 9393-9400 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The participation of metals in the mechanism of the F1-ATPase

Frasch, W., May 31 2000, In : Biochimica et Biophysica Acta - Bioenergetics. 1458, 2-3, p. 310-325 16 p.

Research output: Contribution to journalReview article

32 Scopus citations

Vanadyl as a probe of the function of the F1-ATPase-Mg2+ cofactor

Frasch, W., Dec 1 2000, In : Journal of Bioenergetics and Biomembranes. 32, 5, p. 539-546 8 p.

Research output: Contribution to journalShort survey

6 Scopus citations
1999
10 Scopus citations
7 Scopus citations
1998

Electron spin echo envelope modulation spectroscopy reveals and distinguishes equatorial and axial nitrogen ligands bound to VO2+

LoBrutto, R., Hamstra, B. J., Colpas, G. J., Pecoraro, V. L. & Frasch, W., May 13 1998, In : Journal of the American Chemical Society. 120, 18, p. 4410-4416 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
1997

Structural and Solution Characterization of Mononuclear Vanadium(IV) Complexes That Help To Elucidate the Active Site Structure of the Reduced Vanadium Haloperoxidases

Hamstra, B. J., Houseman, A. L. P., Colpas, G. J., Kampf, J. W., LoBrutto, R., Frasch, W. & Pecoraro, V. L., 1997, In : Inorganic chemistry. 36, 21, p. 4866-4874 9 p.

Research output: Contribution to journalArticle

113 Scopus citations
1996

Catalytic and EPR studies of the βE204Q mutant of the chloroplast F1- ATPase from Chlamydomonas reinhardtii

Hu, C. Y., Houseman, A. L. P., Morgan, L., Webber, A. & Frasch, W., Sep 30 1996, In : Biochemistry. 35, 37, p. 12201-12211 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
1995

Effects of Nucleotides on the Protein Ligands to Metals at the M2 and M3 Metal-Binding Sites of the Spinach Chloroplast F1-ATPase

Houseman, A. L. P., LoBrutto, R. & Frasch, W., Jan 1 1995, In : Biochemistry. 34, 10, p. 3277-3285 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
1994

Characterization of Ligands of a High-Affinity Metal-Binding Site in the Latent Chloroplast F1-ATPase by EPR Spectroscopy of Bound VO2+

Houseman, A. L. P., Morgan, L., LoBrutto, R. & Frasch, W., Apr 1 1994, In : Biochemistry. 33, 16, p. 4910-4917 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Coordination of Nucleotides to Metals at the M2 and M3 Metal-Binding Sites of Spinach Chloroplast F1-ATPase

Houseman, A. L. P., LoBrutto, R. & Frasch, W., Aug 1 1994, In : Biochemistry. 33, 33, p. 10000-10006 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
1992

The Oxygen-Evolving Complex Requires Chloride To Prevent Hydrogen Peroxide Formation

Fine, P. L. & Frasch, W., Feb 1 1992, In : Biochemistry. 31, 48, p. 12204-12210 7 p.

Research output: Contribution to journalArticle

53 Scopus citations
1991

The involvement of photosystem II-generated H2O2 in photoinhibition

Bradley, R. L., Long, K. M. & Frasch, W., Jul 29 1991, In : FEBS Letters. 286, 1-2, p. 209-213 5 p.

Research output: Contribution to journalArticle

34 Scopus citations
1989

ATP hydrolysis catalyzed by a beta subunit preparation purified from the chloroplast energy transducing complex CF1.CF0.

Frasch, W. D., Green, J., Caguiat, J. & Mejia, A., Mar 25 1989, In : The Journal of biological chemistry. 264, 9, p. 5064-5069 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Manganese-Binding Proteins of the Oxygen-Evolving Complex

Mei, R., Green, J. P., Sayre, R. T. & Frasch, W. D., Jun 1 1989, In : Biochemistry. 28, 13, p. 5560-5567 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
5 Scopus citations
1988

Oxidation of Alcohols Catalyzed by the Oxygen-Evolving Complex

Frasch, W. D., Mei, R. & Sanders, M. A., May 1 1988, In : Biochemistry. 27, 10, p. 3715-3719 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
1987

A technique for the determination of protein concentration by neutron activation analysis of silver binding

Frasch, W. D., Larsen, J., Bowlby, N., Apel, I. & Jones, J. D., May 1987, In : Journal of Radioanalytical and Nuclear Chemistry Articles. 112, 1, p. 89-94 6 p.

Research output: Contribution to journalArticle

1 Scopus citations