Timothy Karr

Associate Research Professor

  • 5224 Citations
  • 38 h-Index
1978 …2019

Research output per year

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Research Output

2019

Evolutionary Proteomics Reveals Distinct Patterns of Complexity and Divergence between Lepidopteran Sperm Morphs

Whittington, E., Karr, T. L., Mongue, A. J., Dorus, S., Walters, J. R. & Eyre-Walker, A., Jul 1 2019, In : Genome biology and evolution. 11, 7, p. 1838-1846 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Identification and characterization of the zebra finch (Taeniopygia guttata) sperm proteome

Rowe, M., Skerget, S., Rosenow, M. A. & Karr, T. L., Feb 20 2019, In : Journal of Proteomics. 193, p. 192-204 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reproductive proteomics comes of age

Karr, T. L., Mar 2019, In : Molecular and Cellular Proteomics. 18, p. S1-S5

Research output: Contribution to journalReview article

Open Access

The old and the new: Discovery proteomics identifies putative novel seminal fluid proteins in Drosophila

Karr, T. L., Southern, H., Rosenow, M. A., Gossmann, T. I. & Snook, R. R., Mar 2019, In : Molecular and Cellular Proteomics. 18, p. S23-S33

Research output: Contribution to journalArticle

5 Scopus citations
2017

Comparative sperm proteomics in mouse species with divergent mating systems

Vicens, A., Borziak, K., Karr, T. L., Roldan, E. R. S. & Dorus, S., 2017, In : Molecular biology and evolution. 34, 6, p. 1403-1416 14 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Contrasting patterns of evolutionary constraint and novelty revealed by comparative sperm proteomic analysis in Lepidoptera

Whittington, E., Forsythe, D., Borziak, K., Karr, T. L., Walters, J. R. & Dorus, S., Dec 2 2017, In : BMC Genomics. 18, 1, 931.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2016

The Seminal fluid proteome of the polyandrous Red junglefowl offers insights into the molecular basis of fertility, reproductive ageing and domestication

Borziak, K., Álvarez-Fernández, A., Karr, T. L., Pizzari, T. & Dorus, S., Nov 2 2016, In : Scientific reports. 6, 35864.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
2015

Panning for sperm gold: Isolation and purification of apyrene and eupyrene sperm from lepidopterans

Karr, T. L. & Walters, J. R., Aug 1 2015, In : Insect Biochemistry and Molecular Biology. 63, p. 152-158 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Sperm proteome maturation in the mouse Epididymis

Skerget, S., Rosenow, M. A., Petritis, K. & Karr, T. L., Nov 10 2015, In : PloS one. 10, 11, e0140650.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations
2013

The rhesus macaque (macaca mulatta) sperm proteome

Skerget, S., Rosenow, M., Polpitiya, A., Petritis, K., Dorus, S. & Karr, T. L., Nov 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3052-3067 16 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations
2012

Conserved properties of Drosophila and human spermatozoal mRNA repertoires

Fischer, B. E., Wasbrough, E., Meadows, L. A., Randlet, O., Dorus, S., Karr, T. L. & Russell, S., Jul 7 2012, In : Proceedings of the Royal Society B: Biological Sciences. 279, 1738, p. 2636-2644 9 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Proteomic discovery of diverse immunity molecules in mammalian spermatozoa

Dorus, S., Skerget, S. & Karr, T. L., Aug 1 2012, In : Systems Biology in Reproductive Medicine. 58, 4, p. 218-228 11 p.

Research output: Contribution to journalReview article

Open Access
29 Scopus citations

Re-analysis of the larval testis data on meiotic sex chromosome inactivation revealed evidence for tissue-specific gene expression related to the drosophila X chromosome

Vibranovski, M. D., Zhang, Y. E., Kemkemer, C., Lopes, H. F., Karr, T. L. & Long, M., Jun 12 2012, In : BMC Biology. 10, 49.

Research output: Contribution to journalLetter

Open Access
19 Scopus citations

Segmental dataset and whole body expression data do not support the hypothesis that non-random movement is an intrinsic property of Drosophila retrogenes

Vibranovski, M. D., Zhang, Y. E., Kemkemer, C., Vankuren, N. W., Lopes, H. F., Karr, T. L. & Long, M., 2012, In : BMC Evolutionary Biology. 12, 1, 169.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2011
Open Access
18 Scopus citations

The biology and evolution of polyspermy: Insights from cellular and functional studies of sperm and centrosomal behavior in the fertilized egg

Snook, R. R., Hosken, D. J. & Karr, T. L., Dec 2011, In : Reproduction. 142, 6, p. 779-792 14 p.

Research output: Contribution to journalReview article

Open Access
55 Scopus citations
2010

Direct evidence for postmeiotic transcription during Drosophila melanogaster spermatogenesis

Vibranovski, M. D., Chalopin, D. S., Lopes, H. F., Long, M. & Karr, T. L., Sep 2010, In : Genetics. 186, 1, p. 431-433 3 p.

Research output: Contribution to journalArticle

Open Access
46 Scopus citations

Sperm proteomics reveals intensified selection on mouse sperm membrane and acrosome genes

Dorus, S., Wasbrough, E. R., Busby, J., Wilkin, E. C. & Karr, T. L., 2010, In : Molecular biology and evolution. 27, 6, p. 1235-1246 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

The Drosophila melanogaster sperm proteome-II (DmSP-II)

Wasbrough, E. R., Dorus, S., Hester, S., Howard-Murkin, J., Lilley, K., Wilkin, E., Polpitiya, A., Petritis, K. & Karr, T. L., Oct 10 2010, In : Journal of Proteomics. 73, 11, p. 2171-2185 15 p.

Research output: Contribution to journalArticle

84 Scopus citations
2009

Sperm proteomics and genomics

Dorus, S. & Karr, T. L., Jan 1 2009, Sperm Biology. Elsevier Ltd., p. 435-469 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Stage-specific expression profiling of Drosophila spermatogenesis suggests that meiotic sex chromosome inactivation drives genomic relocation of testis-expressed genes

Vibranovski, M. D., Lopes, H. F., Karr, T. L. & Long, M., Nov 2009, In : PLoS genetics. 5, 11, e1000731.

Research output: Contribution to journalArticle

Open Access
126 Scopus citations

The evolutionary significance of variation in sperm-egg interactions

Karr, T. L., Swanson, W. J. & Snook, R. R., Jan 1 2009, Sperm Biology. Elsevier Ltd., p. 305-365 61 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations
2008

Application of proteomics to ecology and population biology

Karr, T. L., Feb 1 2008, In : Heredity. 100, 2, p. 200-206 7 p.

Research output: Contribution to journalShort survey

Open Access
59 Scopus citations

Recent origins of sperm genes in Drosophila

Dorus, S., Freeman, Z. N., Parker, E. R., Heath, B. D. & Karr, T. L., Oct 2008, In : Molecular biology and evolution. 25, 10, p. 2157-2166 10 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
2007

Fruit flies and the sperm proteome

Karr, T. L., Oct 15 2007, In : Human Molecular Genetics. 16, R2, p. R124-R133

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
2006

Genomic and functional evolution of the Drosophila melanogaster sperm proteome

Dorus, S., Busby, S. A., Gerike, U., Shabanowitz, J., Hunt, D. F. & Karr, T. L., Dec 5 2006, In : Nature Genetics. 38, 12, p. 1440-1445 6 p.

Research output: Contribution to journalArticle

190 Scopus citations

Induced paternal effects mimic cytoplasmic incompatibility in Drosophila

Clark, M. E., Heath, B. D., Anderson, C. L. & Karr, T. L., 2006, In : Genetics. 173, 2, p. 727-734 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2005

Evolution of sexual isolation in laboratory populations: Fitness differences between mating types and the associated hybrid incompatibilities

Alipaz, J. A., Karr, T. L. & Wu, C. I., Apr 1 2005, In : American Naturalist. 165, 4, p. 429-438 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Molecular Genetics of Insect Fertilization

Loppin, B. & Karr, T. L., Jan 1 2005, Comprehensive Molecular Insect Science. Elsevier, Vol. 1-6. p. 213-236 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Origin and neofunctionalization of a Drosophila paternal effect gene essential for zygote viability

Loppin, B., Lepetit, D., Dorus, S., Couble, P. & Karr, T. L., Jan 26 2005, In : Current Biology. 15, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Open Access
73 Scopus citations

The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus

Loppin, B., Bonnefoy, E., Anselme, C., Laurençon, A., Karr, T. L. & Couble, P., Oct 27 2005, In : Nature. 437, 7063, p. 1386-1390 5 p.

Research output: Contribution to journalArticle

238 Scopus citations

Widespread prevalence of Wolbachia in laboratory stocks and the implications for Drosophila research

Clark, M. E., Anderson, C. L., Cande, J. & Karr, T. L., Aug 2005, In : Genetics. 170, 4, p. 1667-1675 9 p.

Research output: Contribution to journalArticle

Open Access
85 Scopus citations
2004

Genetics of hybrid inviability and sterility in Drosophila: Dissection of introgression of D. simulans genes in D. melanogaster genome

Sawamura, K., Karr, T. L. & Yamamoto, M. T., Mar 1 2004, In : Genetica. 120, 1-3, p. 253-260 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Heads or tails: Host-parasite interactions in the Drosophila-Wolbachia system

Veneti, Z., Clark, M. E., Karr, T. L., Savakis, C. & Bourtzis, K., Sep 2004, In : Applied and environmental microbiology. 70, 9, p. 5366-5372 7 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations
2003

Cytoplasmic incompatibility

Bourtzis, K., Braig, H. R. & Karr, T. L., Jan 1 2003, Insect Symbiosis. CRC Press, p. 217-246 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

71 Scopus citations

Cytoplasmic incompatibility and sperm cyst infection in different Drosophila-Wolbachia associations

Veneti, Z., Clark, M. E., Zabalou, S., Karr, T. L., Savakis, C. & Bourtzis, K., Jun 1 2003, In : Genetics. 164, 2, p. 545-552 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Wolbachia distribution and cytoplasmic incompatibility during sperm development: The cyst as the basic cellular unit of CI expression

Clark, M. E., Veneti, Z., Bourtzis, K. & Karr, T. L., Feb 2003, In : Mechanisms of Development. 120, 2, p. 185-198 14 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations
2002

Diploidy restoration in Wolbachia-infected Muscidifurax uniraptor (Hymenoptera: Pteromalidae)

Gottlieb, Y., Zchori-Fein, E., Werren, J. H. & Karr, T. L., Nov 1 2002, In : Journal of Invertebrate Pathology. 81, 3, p. 166-174 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
Open Access
20 Scopus citations

Hsp70 and thermal pretreatment mitigate developmental damage caused by mitotic poisons in Drosophila

Isaenko, O. A., Karr, T. L. & Feder, M. E., Jul 2002, In : Cell Stress and Chaperones. 7, 3, p. 297-308 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The distribution and proliferation of the intracellular bacteria Wolbachia during spermatogenesis in Drosophila

Clark, M. E., Veneti, Z., Bourtzis, K. & Karr, T. L., Feb 20 2002, In : Mechanisms of Development. 111, 1-2, p. 3-15 13 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations
2001

A newly discovered bacterium associated with parthenogenesis and a change in host selection behavior in parasitoid wasps

Zchori-Fein, E., Gottlieb, Y., Kelly, S. E., Brown, J. K., Wilson, J. M., Karr, T. L. & Hunter, M. S., Oct 23 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 22, p. 12555-12560 6 p.

Research output: Contribution to journalArticle

Open Access
208 Scopus citations

Centrosome inheritance: A central 'in-egg-ma' solved?

Karr, T. L., Jan 9 2001, In : Current Biology. 11, 1, p. R21-R24

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Gametic incompatibilities between races of Drosophila melanogaster

Alipaz, J. A., Wu, C. I. & Karr, T. L., Apr 22 2001, In : Proceedings of the Royal Society B: Biological Sciences. 268, 1469, p. 789-795 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Wolbachia: Evolutionary novelty in a rickettsial bacteria

Anderson, C. L. & Karr, T. L., Nov 9 2001, In : BMC Evolutionary Biology. 1, 10.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations
2000

Offsetting effects of Wolbachia infection and heat shock on sperm production in Drosophila simulans: Analyses of fecundity, fertility and accessory gland proteins

Snook, R. R., Cleland, S. Y., Wolfner, M. F. & Karr, T. L., May 1 2000, In : Genetics. 155, 1, p. 167-178 12 p.

Research output: Contribution to journalArticle

109 Scopus citations

Virtual biology in the CAVE

Karr, T. L. & Brady, R., May 1 2000, In : Trends in Genetics. 16, 5, p. 231-232 2 p.

Research output: Contribution to journalComment/debate

8 Scopus citations
1999

Genetic analysis of viable Hsp90 alleles reveals a critical role in Drosophila spermatogenesis

Yue, L., Karr, T. L., Nathan, D. F., Swift, H., Srinivasans, S. & Lindquist, S., Mar 1 1999, In : Genetics. 151, 3, p. 1065-1079 15 p.

Research output: Contribution to journalArticle

96 Scopus citations

Interaction of drosophila and its endosymbiont wolbachia: natural heat shock and the overcoming of sexual incompatibility

Feder, M. E., Karr, T. L., Yang, W., Hoekstra, J. M. & James, A. C., 1999, In : American Zoologist. 39, 2, p. 363-373 11 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Sperm competition: Defining the rules of engagement

Karr, T. L. & Pitnick, S., Oct 21 1999, In : Current Biology. 9, 20, p. R787-R790

Research output: Contribution to journalArticle

Open Access
9 Scopus citations