• 10609 Citations
  • 53 h-Index
1970 …2019
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Research Output 1970 2019

1986
16 Citations (Scopus)

M1 RNA, the RNA subunit of Escherichia coli ribonuclease P, can undergo a pH-sensitive conformational change

Altman, S. & Guerrier-Takada, C., 1986, In : Biochemistry. 25, 6, p. 1205-1208 4 p.

Research output: Contribution to journalArticle

Ribonuclease P
Escherichia coli
Conformations
RNA
Cell Extracts
31 Citations (Scopus)

M1 RNA with large terminal deletions retains its catalytic activity

Guerrier-Takada, C. & Altman, S., Apr 25 1986, In : Cell. 45, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Catalyst activity
Nucleotides
RNA
Nucleic Acid Conformation
Catalytic RNA
142 Citations (Scopus)

Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli

Guerrier-Takada, C., Haydock, K., Allen, L. & Altman, S., 1986, In : Biochemistry. 25, 7, p. 1509-1515 7 p.

Research output: Contribution to journalArticle

Ribonuclease P
Escherichia coli
Metal ions
Metals
RNA
23 Citations (Scopus)

Reconstitution of RNAase P activity using inactive subunits from E. coli and HeLa cells

Gold, H. A. & Altman, S., Jan 31 1986, In : Cell. 44, 2, p. 243-249 7 p.

Research output: Contribution to journalArticle

HeLa Cells
Escherichia coli
RNA
DNA
Assays
27 Citations (Scopus)
Ribonuclease P
Site-Directed Mutagenesis
RNA
Escherichia coli
Genes
1985
33 Citations (Scopus)

A catalytic RNA and its gene from Salmonella typhimurium

Baer, M. & Altman, S., 1985, In : Science. 228, 4702, p. 999-1002 4 p.

Research output: Contribution to journalArticle

Catalytic RNA
Salmonella typhimurium
RNA
Genes
Nucleotides
126 Citations (Scopus)

Characterization of an RNase P activity from HeLa cell mitochondria. Comparison with the cytosol RNase P activity

Doersen, C. J., Guerrier-Takada, C., Altman, S. & Attardi, G., 1985, In : Journal of Biological Chemistry. 260, 10, p. 5942-5949 8 p.

Research output: Contribution to journalArticle

Ribonuclease P
Mitochondria
HeLa Cells
Cytosol
RNA, Transfer, Tyr
1 Citation (Scopus)

Novel non-suppressing mutants of Escherichia coli tRNATyr su3 +

Furdon, P. & Altman, S., Apr 11 1985, In : Nucleic Acids Research. 13, 7, p. 2583-2601 19 p.

Research output: Contribution to journalArticle

RNA, Transfer, Tyr
Transfer RNA
Escherichia coli
Sequence Deletion
Ribosomes
1984
19 Citations (Scopus)

Aspects of biochemical catalysis

Altman, S., 1984, In : Cell. 36, 2, p. 237-239 3 p.

Research output: Contribution to journalArticle

Catalysis
RNA
Proteins
Nucleic Acids
Molecules

Aspects of the reaction catalyzed by M1 RNA

Altman, S., Baer, M., Guerrier-Takada, C. & Nathan, L., 1984, In : Federation Proceedings. 43, 6

Research output: Contribution to journalArticle

RNA
157 Citations (Scopus)

Catalytic activity of an RNA molecule prepared by transcription in vitro

Guerrier Takada, C. & Altman, S., 1984, In : Science. 223, 4633, p. 285-286 2 p.

Research output: Contribution to journalArticle

Catalytic RNA
Ribonuclease P
RNA
RNA Precursors
Escherichia coli
56 Citations (Scopus)

Cleavage of tRNA precursors by the RNA subunit of E. coli ribonuclease P (M1 RNA) is influenced by 3′-proximal CCA in the substrates

Guerrier-Takada, C., McClain, W. H. & Altman, S., 1984, In : Cell. 38, 1, p. 219-224 6 p.

Research output: Contribution to journalArticle

RNA Precursors
Transfer RNA
RNA
Escherichia coli
Bacteriophage T4
41 Citations (Scopus)

Structure in solution of M1 RNA, the catalytic subunit of ribonuclease P from Escherichia coli

Guerrier-Takada, C. & Altman, S., 1984, In : Biochemistry. 23, 26, p. 6327-6334 8 p.

Research output: Contribution to journalArticle

Ribonuclease P
Escherichia coli
RNA
Magnesium Chloride
Buffers
1983
11 Citations (Scopus)

A G43 to U43 mutation in E. coli tRNATyrsu3 + which affects processing by RNase P

Furdon, P. J., Guerrier-takada, C. & Altman, S., Mar 11 1983, In : Nucleic Acids Research. 11, 5, p. 1491-1505 15 p.

Research output: Contribution to journalArticle

Ribonuclease P
Escherichia coli
Escherichia Coli
Transfer RNA
Mutation
1 Citation (Scopus)

Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

Akaboshi, E. & Altman, S., Jun 11 1983, In : Nucleic Acids Research. 11, 11, p. 3687-3702 16 p.

Research output: Contribution to journalArticle

Endoribonucleases
Saturn
Hydroxyl Radical
Phosphates
pyrimidine
25 Citations (Scopus)
Ribonuclease P
3' Flanking Region
Open Reading Frames
RNA
Escherichia coli
1771 Citations (Scopus)

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N. & Altman, S., 1983, In : Cell. 35, 3 PART 2, p. 849-857 9 p.

Research output: Contribution to journalArticle

Ribonuclease P
Catalytic Domain
RNA
Spermidine
Enzymes
1982
8 Citations (Scopus)

14 tRNA Processing Enzymes from Escherichia coli

Kole, R. & Altman, S., 1982, In : Enzymes. 15, C, p. 469-483 15 p.

Research output: Contribution to journalArticle

Transfer RNA
Escherichia coli
Enzymes
Endoribonucleases
Ribonuclease III
18 Citations (Scopus)

Large deletion mutants of Escherichia coli tRNA1 Tyr

McCorkle, G. M. & Altman, S., Feb 25 1982, In : Journal of Molecular Biology. 155, 2, p. 83-103 21 p.

Research output: Contribution to journalArticle

Base Pairing
Escherichia coli
Aza Compounds
Quinacrine
Bacteriophages
95 Citations (Scopus)

Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli

Reed, R. E., Baer, M. F., Guerrier-Takada, C., Donis-Keller, H. & Altman, S., 1982, In : Cell. 30, 2, p. 627-636 10 p.

Research output: Contribution to journalArticle

Ribonuclease P
Gene encoding
Escherichia coli
Nucleotides
RNA

Unusual suppression properties of lysogens containing derivatives of φ{symbol}80 psu3 +

Feinstein, S. I. & Altman, S., Oct 1982, In : MGG Molecular & General Genetics. 187, 2, p. 347-353 7 p.

Research output: Contribution to journalArticle

Hot Temperature
varespladib methyl
Amber
Nonsense Codon
Bacteriophages
1981
22 Citations (Scopus)

An E. coli gene coding for a protamine-like protein

Altman, S., Model, P., Dixon, G. H. & Wosnick, M. A., 1981, In : Cell. 26, 3 PART 1, p. 299-304 6 p.

Research output: Contribution to journalArticle

Protamines
Escherichia coli
Genes
Bacteriophages
DNA
10 Citations (Scopus)

Biosynthesis of transfer RN

Daniel, V. & Altman, S., 1981, In : Critical Reviews in Biochemistry and Molecular Biology. 9, 4, p. 253-292 40 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Properties of purified ribonuclease P from Escherichia coli

Kole, R. & Altman, S., 1981, In : Biochemistry. 20, 7, p. 1902-1906 5 p.

Research output: Contribution to journalArticle

Ribonuclease P
Escherichia coli
RNA Precursors
RNA
Catalyst activity
21 Citations (Scopus)

Transfer RNA processing enzymes

Altman, S., 1981, In : Cell. 23, 1, p. 3-4 2 p.

Research output: Contribution to journalArticle

Transfer RNA
Enzymes
1980
88 Citations (Scopus)

E. coli RNAase P has a required RNA component in vivo

Kole, R., Baer, M. F., Stark, B. C. & Altman, S., 1980, In : Cell. 19, 4, p. 881-887 7 p.

Research output: Contribution to journalArticle

Escherichia coli
Hot Temperature
RNA
Mutation
Proteins
8 Citations (Scopus)

Identification of ribonuclease P activity from chick embryos

Bowman, E. J. & Altman, S., Jun 13 1980, In : BBA - Enzymology. 613, 2, p. 439-447 9 p.

Research output: Contribution to journalArticle

Ribonuclease P
Chick Embryo
KB Cells
RNA, Transfer, Tyr
Monovalent Cations
29 Citations (Scopus)

Veal heart ribonuclease P has an essential RNA component.

Akaboshi, E., Guerrier-Takada, C. & Altman, S., Sep 30 1980, In : Biochemical and Biophysical Research Communications. 96, 2, p. 831-837 7 p.

Research output: Contribution to journalArticle

Ribonuclease P
Ribonuclease T1
Micrococcal Nuclease
Pancreatic Ribonuclease
Density Gradient Centrifugation
1979
38 Citations (Scopus)

In vitro processing of B. mori transfer RNA precursor molecules

Garber, R. L. & Altman, S., 1979, In : Cell. 17, 2, p. 389-397 9 p.

Research output: Contribution to journalArticle

Morus
Bombyx
RNA Precursors
3'-nucleotidase
Escherichia coli
58 Citations (Scopus)
Ribonuclease P
RNA
Proteins
1978
33 Citations (Scopus)

Context effects on nonsense codon suppression in Escherichia coli

Feinstein, S. I. & Altman, S., 1978, In : Genetics. 88, 2, p. 201-219 19 p.

Research output: Contribution to journalArticle

Anthranilate Synthase
Tryptophan Synthase
Genetic Suppression
Genetic Code
Nonsense Codon
4 Citations (Scopus)

Endoribonuclease activity associated with animal RNA viruses

Kolakofsky, D. & Altman, S., 1978, In : Journal of Virology. 25, 1, p. 274-284 11 p.

Research output: Contribution to journalArticle

endoribonucleases
Endoribonucleases
Sendai virus
Vesiculovirus
Vesicular Stomatitis
17 Citations (Scopus)

Identification of precursor molecules to individual tRNA species from Bombyx mori

Garber, R. L., Siddiqui, M. A. Q. & Altman, S., 1978, In : Proceedings of the National Academy of Sciences of the United States of America. 75, 2, p. 635-639 5 p.

Research output: Contribution to journalArticle

Bombyx
RNA Precursors
RNA, Transfer, Ala
Transfer RNA
Gels
184 Citations (Scopus)

Ribonuclease P: An enzyme with an essential RNA component

Stark, B. C., Kole, R., Bowman, E. J. & Altman, S., 1978, In : Proceedings of the National Academy of Sciences of the United States of America. 75, 8, p. 3717-3721 5 p.

Research output: Contribution to journalArticle

Ribonuclease P
RNA
Enzymes
1977
34 Citations (Scopus)

Coding properties of an ochre-suppressing derivative of Escherichia coli tRNAI Tyr

Feinstein, S. I. & Altman, S., May 25 1977, In : Journal of Molecular Biology. 112, 3, p. 453-470 18 p.

Research output: Contribution to journalArticle

Transfer RNA
Escherichia coli
Mutation
Terminator Codon
Galactosidases
2 Citations (Scopus)

Influence of the A15 mutation on the conformational energy balance in Escherichia coli tRNATyr

Leon, V., Altman, S. & Crothers, D. M., Jun 15 1977, In : Journal of Molecular Biology. 113, 1, p. 253-265 13 p.

Research output: Contribution to journalArticle

RNA, Transfer, Tyr
Escherichia coli
Mutation
Entropy
Transfer RNA
1976
5 Citations (Scopus)

A Modified Uridine in the Anticodon of E. Coli

Altman, S., 1976, In : Nucleic Acids Research. 3, 2, p. 441-448 8 p.

Research output: Contribution to journalArticle

Anticodon
Uridine
ribonuclease T(2)
Escherichia coli
Thin Layer Chromatography
30 Citations (Scopus)

Identification of a ribonuclease P-like activity from human KB cells

Koski, R. A., Bothwell, A. L. M. & Altman, S., 1976, In : Cell. 9, 1, p. 101-116 16 p.

Research output: Contribution to journalArticle

Ribonuclease P
KB Cells
Endoribonucleases
Human Activities
Escherichia coli
98 Citations (Scopus)

Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA

Bothwell, A. L. M., Garber, R. L. & Altman, S., 1976, In : Journal of Biological Chemistry. 251, 23, p. 7709-7716 8 p.

Research output: Contribution to journalArticle

Bacterial RNA
Oligoribonucleotides
Ribonucleases
Escherichia coli
Hydrogen bonds
40 Citations (Scopus)

Ribonuclease P substrate specificity: Cleavage of a bacteriophage phi80 induced RNA

Bothwell, A. L. M., Stark, B. C. & Altman, S., 1976, In : Proceedings of the National Academy of Sciences of the United States of America. 73, 6, p. 1912-1916 5 p.

Research output: Contribution to journalArticle

Ribonuclease P
Substrate Specificity
Bacteriophages
RNA
1975
2 Citations (Scopus)

9-Aminoacridine mutagenesis of bacteriophage T4 intracellular DNA

Altman, S. & Warner, V., Dec 1975, In : MGG Molecular & General Genetics. 138, 4, p. 333-343 11 p.

Research output: Contribution to journalArticle

Aminacrine
Bacteriophage T4
Mutagenesis
DNA
Bacteriophages
56 Citations (Scopus)

Biosynthesis of transfer RNA in Escherichia coli

Altman, S., 1975, In : Cell. 4, 1, p. 21-29 9 p.

Research output: Contribution to journalReview article

Genetic Transcription
Bacterial RNA
Chemical Models
Endonucleases
Structural Models
1 Citation (Scopus)

Characterization of ribonuclease NU cleavage sites in a bacteriophage phi80 induced ribonucleic acid

Bothwell, A. L. M. & Altman, S., 1975, In : Journal of Biological Chemistry. 250, 4, p. 1460-1463 4 p.

Research output: Contribution to journalArticle

Bacteriophages
Ribonucleases
Endoribonucleases
RNA
Tissue culture
13 Citations (Scopus)

Partial purification and properties of an endoribonuclease isolated from human KB cells

Bothwell, A. L. M. & Altman, S., 1975, In : Journal of Biological Chemistry. 250, 4, p. 1451-1459 9 p.

Research output: Contribution to journalArticle

Endoribonucleases
KB Cells
Ribonucleases
Purification
RNA, Transfer, Tyr
21 Citations (Scopus)

Processing of E. coli tRNA(Tyr) precursor RNA in vitro

Altman, S., Bothwell, A. L. M. & Stark, B. C., 1975, In : Brookhaven Symposia in Biology. Vol. 26, p. 12-25 14 p.

Research output: Contribution to journalArticle

RNA, Transfer, Tyr
Genetic Transcription
Bacterial RNA
Nucleic Acid Conformation
Species Specificity
1974
4 Citations (Scopus)

Separation of E. coli tRNATyr precursor RNA from E. coli tRNA by hydroxyapatite chromatography

Altman, S. & Stark, B. C., 1974, In : Analytical Biochemistry. 59, 2, p. 547-554 8 p.

Research output: Contribution to journalArticle

RNA, Transfer, Tyr
RNA Precursors
Durapatite
Transfer RNA
Chromatography
1973
50 Citations (Scopus)

Identification of tRNA precursor molecules made by phage T4

Guthrie, C., Seidman, J. G., Altman, S., Barrell, B. G., Smith, J. D. & McClain, W. H., Nov 7 1973, In : Nature: New biology. 246, 149, p. 6-11 6 p.

Research output: Contribution to journalArticle

Phosphorus Radioisotopes
Thin layer chromatography
Bacteriophages
RNA Precursors
Viral RNA
33 Citations (Scopus)
RNA, Transfer, Tyr
Nucleotides
Escherichia coli
In Vitro Techniques
21 Citations (Scopus)

RNA precursor molecules and ribonucleases in E. coli

Altman, S. & Robertson, H. D., Mar 1973, In : Molecular and Cellular Biochemistry. 1, 1, p. 83-93 11 p.

Research output: Contribution to journalArticle

RNA Precursors
Ribonucleases
Escherichia coli
RNA
Molecules
1972
209 Citations (Scopus)

Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor.

Robertson, H. D., Altman, S. & Smith, J. D., Aug 25 1972, In : Journal of Biological Chemistry. 247, 16, p. 5243-5251 9 p.

Research output: Contribution to journalArticle

Phosphorus Isotopes
Microbial Genetics
Bacterial RNA
pH
Cell Fractionation