• 11030 Citations
  • 53 h-Index
1970 …2020

Research output per year

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Research Output

2020

A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding

Terekhov, S. S., Mokrushina, Y. A., Nazarov, A. S., Zlobin, A., Zalevsky, A., Bourenkov, G., Golovin, A., Belogurov, A., Osterman, I. A., Kulikova, A. A., Mitkevich, V. A., Lou, H. J., Turk, B. E., Wilmanns, M., Smirnov, I. V., Altman, S. & Gabibov, A. G., Jun 2020, In : Science Advances. 6, 26, eaaz9861.

Research output: Contribution to journalArticle

Open Access

Peptide conjugated morpholinos for management of the huanglongbing pathosystem

Sandoval-Mojica, A. F., Altman, S., Hunter, W. B. & Pelz-Stelinski, K. S., 2020, (Accepted/In press) In : Pest Management Science.

Research output: Contribution to journalArticle

2019

Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties

Miroshnichenko, S. K., Patutina, O. A., Burakova, E. A., Chelobanov, B. P., Fokina, A. A., Vlassov, V. V., Altman, S., Zenkova, M. A. & Stetsenko, D. A., Jan 22 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 4, p. 1229-1234 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Novel peptide conjugates of modified oligonucleotides for inhibition of bacterial RNase P

Novopashina, D., Vorobyeva, M., Nazarov, A., Davydova, A., Danilin, N., Koroleva, L., Matveev, A., Bardasheva, A., Tikunova, N., Kupryushkin, M., Pyshnyi, D., Altman, S. & Venyaminova, A., Jul 2019, In : Frontiers in Pharmacology. 10, 813.

Research output: Contribution to journalArticle

Open Access
2018

Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P

Novopashina, D. S., Nazarov, A. S., Vorobjeva, M. A., Kuprushkin, M. S., Davydova, A. S., Lomzov, A. A., Pyshnyi, D. V., Altman, S. & Venyaminova, A. G., Nov 1 2018, In : Molecular Biology. 52, 6, p. 905-912 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P

Novopashina, D. S., Nazarov, A. S., Vorobjeva, M. A., Kuprushkin, M. S., Davydova, A. S., Lomzov, A. A., Pyshnyi, D. V., Altman, S. & Venyaminova, A. G., Nov 1 2018, In : Molekuliarnaia biologiia. 52, 6, p. 1045-1054 10 p.

Research output: Contribution to journalArticle

2017

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity

Terekhov, S. S., Smirnov, I. V., Stepanova, A. V., Bobik, T. V., Mokrushina, Y. A., Ponomarenko, N. A., Belogurov, A. A., Rubtsova, M. P., Kartseva, O. V., Gomzikova, M. O., Moskovtsev, A. A., Bukatin, A. S., Dubina, M. V., Kostryukova, E. S., Babenko, V. V., Vakhitova, M. T., Manolov, A. I., Malakhova, M. V., Kornienko, M. A., Tyakht, A. V. & 5 others, Vanyushkina, A. A., Ilina, E. N., Masson, P., Gabibov, A. G. & Altman, S., Mar 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 10, p. 2550-2555 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

The origin of life, “the World of RNA,” and the problem of antibiotic resistance

Altman, S., Nov 1 2017, In : Herald of the Russian Academy of Sciences. 87, 6, p. 474-479 6 p.

Research output: Contribution to journalArticle

2016

Aptamers against pathogenic microorganisms

Davydova, A., Vorobjeva, M., Pyshnyi, D., Altman, S., Vlassov, V. & Venyaminova, A., Nov 1 2016, In : Critical Reviews in Microbiology. 42, 6, p. 847-865 19 p.

Research output: Contribution to journalReview article

33 Scopus citations

Combinatorial development of antibacterial Zr-Cu-Al-Ag thin film metallic glasses

Liu, Y., Padmanabhan, J., Cheung, B., Liu, J., Chen, Z., Scanley, B. E., Wesolowski, D., Pressley, M., Broadbridge, C. C., Altman, S., Schwarz, U. D., Kyriakides, T. R. & Schroers, J., May 27 2016, In : Scientific Reports. 6, 26950.

Research output: Contribution to journalArticle

37 Scopus citations
2015

Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III

Serruya, R., Orlovetskie, N., Reiner, R., Dehtiar-Zilber, Y., Wesolowski, D., Altman, S. & Jarrous, N., Apr 24 2015, In : Nucleic Acids Research. 43, 11, p. 5442-5450 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum

Garg, A., Wesolowski, D., Alonso, D., Deitsch, K. W., Ben Mamoun, C. & Altman, S., Sep 22 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 38, p. 11935-11940 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Twenty years

Altman, S., Apr 1 2015, In : RNA. 21, 4, p. 513-514 2 p.

Research output: Contribution to journalShort survey

1 Scopus citations
2014

Antibiotics present and future

Altman, S., Jan 3 2014, In : FEBS Letters. 588, 1, p. 1-2 2 p.

Research output: Contribution to journalReview article

9 Scopus citations
2013

A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model

Sawyer, A. J., Wesolowski, D., Gandotra, N., Stojadinovic, A., Izadjoo, M., Altman, S. & Kyriakides, T. R., Jan 1 2013, In : International Journal of Pharmaceutics. 453, 2, p. 651-655 5 p.

Research output: Contribution to journalArticle

25 Scopus citations
25 Scopus citations

Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum

Augagneur, Y., Jaubert, L., Schiavoni, M., Pachikara, N., Garg, A., Usmani-Brown, S., Wesolowski, D., Zeller, S., Ghosal, A., Cornillot, E., Said, H. M., Kumar, P., Altman, S. & Ben Mamoun, C., Jul 12 2013, In : Journal of Biological Chemistry. 288, 28, p. 20558-20567 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

The RNA-protein world

Altman, S., May 1 2013, In : RNA. 19, 5, p. 589-590 2 p.

Research output: Contribution to journalReview article

9 Scopus citations
2012

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum

Augagneur, Y., Wesolowski, D., Tae, H. S., Altman, S. & Mamoun, C. B., Apr 17 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6235-6240 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

RNA therapeutics: Beyond RNA interference and antisense oligonucleotides

Kole, R., Krainer, A. R. & Altman, S., Feb 1 2012, In : Nature Reviews Drug Discovery. 11, 2, p. 125-140 16 p.

Research output: Contribution to journalReview article

667 Scopus citations

U.S. basic research: Still number one?

Altman, S., Sep 28 2012, In : Science. 337, 6102, 1 p.

Research output: Contribution to journalLetter

2011

Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes

Wesolowski, D., Tae, H. S., Gandotra, N., Llopis, P., Shen, N. & Altman, S., Oct 4 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 40, p. 16582-16587 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Inactivation of expression of two genes in Saccharomyces cerevisiae with the external guide sequence methodology

Cheng, X., Ko, J. H. & Altman, S., Mar 1 2011, In : RNA. 17, 3, p. 544-549 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ribonuclease P

Altman, S., Oct 27 2011, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1580, p. 2936-2941 6 p.

Research output: Contribution to journalReview article

23 Scopus citations

RNA binding properties of conserved protein subunits of human RNase P

Reiner, R., Alfiya-Mor, N., Berrebi-Demma, M., Wesolowski, D., Altman, S. & Jarrous, N., Jul 1 2011, In : Nucleic acids research. 39, 13, p. 5704-5714 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

History of RNase P and overview of its catalytic activity

Altman, S., Jan 1 2010, Ribonuclease P. liu, F. & Altman, S. (eds.). p. 1-15 15 p. (Protein Reviews; vol. 10).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Inhibition of gene expression by RNase P

Lundblad, E. W. & Altman, S., Jul 31 2010, In : New Biotechnology. 27, 3, p. 212-221 10 p.

Research output: Contribution to journalReview article

32 Scopus citations

Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA

Xiao, G., Wesolowski, D., Izadjoo, M. & Altman, S., Nov 1 2010, In : RNA. 16, 11, p. 2218-2225 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2009

Inactivation of expression of several genes in a variety of bacterial species by EGS technology

Shen, N., Ko, J. H., Xiao, G., Wesolowski, D., Shan, G., Geller, B., Lzadjoo, M. & Altman, S., May 19 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 20, p. 8163-8168 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2008

Inhibition of expression in Escherichia coli of a virulence regulator MglB of Francisella tularensis using external guide sequence technology

Xiao, G., Lundblad, E. W., Izadjoo, M. & Altman, S., Nov 13 2008, In : PloS one. 3, 11, e3719.

Research output: Contribution to journalArticle

8 Scopus citations

Inhibition of expression of virulence genes of Yersinia pestis in Escherichia coli by external guide sequences and RNase P

Ko, J. H., Izadjoo, M. & Altman, S., Aug 1 2008, In : RNA. 14, 8, p. 1656-1662 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
16 Scopus citations

RNase P cleaves the adenine riboswitch and stabilizes pbuE mRNA in Bacillus subtilis

Seif, E. & Altman, S., Jun 1 2008, In : RNA. 14, 6, p. 1237-1243 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
2007

A noncoding RNA in Saccharomyces cerevisiae is an RNase P substrate

Yang, L. & Altman, S., May 1 2007, In : RNA. 13, 5, p. 682-690 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

An overview of the RNA world - For now

Altman, S., Jul 1 2007, In : Biological Chemistry. 388, 7, p. 663-664 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

A view of RNase P

Altman, S., Aug 20 2007, In : Molecular BioSystems. 3, 9, p. 604-607 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

Foreword

Altman, S., Jan 1 2007, MicroRNAs: From Basic Science to Disease Biology. Cambridge University Press, p. xxv-xxvi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

25 Scopus citations
2005

Analysis of putative RNase P RNA from orthopoxviruses

Yang, L., Wesolowski, D., Li, Y. & Altman, S., Dec 2 2005, In : Journal of molecular biology. 354, 3, p. 529-535 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

An open letter to Elias Zerhouni [1]

Altman, S., Bassler, B. L., Beckwith, J., Belfort, M., Berg, H. C., Bloom, B., Brenchley, J. E., Campbell, A., Collier, R. J., Connell, N., Cozzarelli, N. R., Craig, N. L., Darst, S., Ebright, R. H., Elledge, S. J., Falkow, S., Galan, J. E., Gottesman, M., Gourse, R., Grindley, N. D. F. & 30 others, Gross, C. A., Grossman, A., Hochschild, A., Howe, M., Hurwitz, J., Isberg, R. R., Kaplan, S., Kornberg, A., Kustu, S. G., Landick, R. C., Landy, A., Levy, S. B., Losick, R., Long, S. R., Maloy, S. R., Mekalanos, J. J., Neidhardt, F. C., Pace, N. R., Ptashne, M., Roberts, J. W., Roth, J. R., Rothman-Denes, L. B., Salyers, A., Schaechter, M., Shapiro, L., Silhavy, T. J., Simon, M. I., Walker, G., Yanofsky, C. & Zinder, N., Mar 4 2005, In : Science. 307, 5714, p. 1409-1410 2 p.

Research output: Contribution to journalLetter

22 Scopus citations

Foreword

Altman, S., Jan 1 2005, Non-viral Gene Therapy: Gene Design and Delivery. Springer-Verlag Tokyo, p. V

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Masters of DNA.

Altman, S., Apr 15 2005, In : The Journal of biological chemistry. 280, 15, p. 14361-14365 5 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Regulated expression of functional external guide sequences in mammalian cells using a U6 RNA polymerase III promoter

Kovrigina, E., Yang, L., Pfund, E. & Altman, S., Oct 1 2005, In : RNA. 11, 10, p. 1588-1595 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

RNase P cleaves transient structures in some riboswitches

Altman, S., Wesolowski, D., Guerrier-Takada, C. & Li, Y., Aug 9 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 32, p. 11284-11289 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Using ethics to fight bioterrorism [1] (multiple letters)

Frankel, M. S., Li, L., Green, S. K., Rath, J., Jank, B., Perman, B., Agre, P. C., Altman, S., Curl, R. F., Wiesel, T. N., West-Eberhard, M. J., Somerville, M. & Atlas, R., Aug 12 2005, In : Science. 309, 5737, p. 1012-1017 6 p.

Research output: Contribution to journalLetter

3 Scopus citations
2004

Disruption of type III secretion in Salmonella enterica serovar typhimurium by external guide sequences

McKinney, J. S., Zhang, H., Kubori, T., Galán, J. E. & Altman, S., 2004, In : Nucleic acids research. 32, 2, p. 848-854 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
21 Scopus citations

In search of RNase P RNA from microbial genomes

Li, Y. & Altman, S., Oct 1 2004, In : RNA. 10, 10, p. 1533-1540 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Polarity effects in the lactose operon of Escherichia coli

Li, Y. & Altman, S., May 21 2004, In : Journal of molecular biology. 339, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2003
79 Scopus citations