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Research Output 1998 2017

  • 660 Citations
  • 14 h-Index
  • 26 Article
  • 23 Conference contribution
  • 1 Review article
2017
5 Citations (Scopus)

Characterization and comparison of three microfabrication methods to generate out-of-plane microvortices for single cell rotation and 3D imaging

Shetty, R. M., Myers, J. R., Sreenivasulu, M., Teller, W., Vela, J., Houkal, J., Chao, S-H., Johnson, R. H., Kelbauskas, L., Wang, H. & Meldrum, D., Jan 1 2017, In : Journal of Micromechanics and Microengineering. 27, 1, 015004.

Research output: Contribution to journalArticle

Microfabrication
Photolithography
Vortex flow
Imaging techniques
Fluidics
10 Citations (Scopus)

Improved Performance of Loop-Mediated Isothermal Amplification Assays via Swarm Priming

Martineau, R. L., Murray, S. A., Ci, S., Gao, W., Chao, S-H. & Meldrum, D., Jan 3 2017, In : Analytical Chemistry. 89, 1, p. 625-632 8 p.

Research output: Contribution to journalArticle

Amplification
Assays
Speed indicators
Bacteriophages
Reaction products
1 Citation (Scopus)

Optical computed tomography for spatially isotropic four-dimensional imaging of live single cells

Kelbauskas, L., Shetty, R., Cao, B., Wang, K. C., Smith, D., Wang, H., Chao, S-H., Gangaraju, S., Ashcroft, B., Kritzer, M., Glenn, H., Johnson, R. H. & Meldrum, D., Dec 1 2017, In : Science advances. 3, 12, e1602580.

Research output: Contribution to journalArticle

Optical Tomography
Tomography
X-Rays
Mitochondrial Dynamics
Myeloid Leukemia
2015
6 Citations (Scopus)

Measuring gene expression in single bacterial cells: Recent advances in methods and micro-devices

Shi, X., Gao, W., Wang, J., Chao, S-H., Zhang, W. & Meldrum, D., Jan 1 2015, In : Critical Reviews in Biotechnology. 35, 4, p. 448-460 13 p.

Research output: Contribution to journalArticle

Gene Expression
Equipment and Supplies
Lab-On-A-Chip Devices
Population
Bacterial Genes
17 Citations (Scopus)

Parallel RNA extraction using magnetic beads and a droplet array

Shi, X., Chen, C. H., Gao, W., Chao, S-H. & Meldrum, D., Feb 21 2015, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 15, 4, p. 1059-1065 7 p.

Research output: Contribution to journalArticle

RNA
Diatoms
Microtechnology
Messenger RNA
Lab-on-a-chip
164 Citations (Scopus)

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

Brennand, K., Savas, J. N., Kim, Y., Tran, N., Simone, A., Hashimoto-Torii, K., Beaumont, K. G., Kim, H. J., Topol, A., Ladran, I., Abdelrahim, M., Matikainen-Ankney, B., Chao, S-H., Mrksich, M., Rakic, P., Fang, G., Zhang, B., Yates, J. R. & Gage, F. H., Jan 1 2015, In : Molecular Psychiatry. 20, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Schizophrenia
Stem Cells
Gene Expression
Neurons
2014

DEEP-well microfluidics for arrayed colorimetric LAMP analysis

Martineau, R. L., Ci, S., Houkal, J., Gao, W., Chao, S-H. & Meldrum, D., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1009-1011 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Amplification
Lighting
Cameras
Geometry

Live single cell rotation using hydrodynamic microvortex flow and optical trapping

Shetty, R. M., Myers, J. R., Teller, W. L., Shabilla, A., Smith, D., Houkal, J., Vela, J., Chao, S-H., Johnson, R. H., Kelbauskas, L., Wang, H. & Meldrum, D., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1545-1547 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrodynamics
Imaging techniques
Microfluidics
Fabrication
57 Citations (Scopus)

Roles of Heat Shock Factor 1 in Neuronal Response to Fetal Environmental Risks and Its Relevance to Brain Disorders

Hashimoto-Torii, K., Torii, M., Fujimoto, M., Nakai, A., ElFatimy, R., Mezger, V., Ju, M. J., Ishii, S., Chao, S-H., Brennand, K. J., Gage, F. H. & Rakic, P., May 7 2014, In : Neuron. 82, 3, p. 560-572 13 p.

Research output: Contribution to journalArticle

Brain Diseases
Shock
Seizures
Hot Temperature
Induced Pluripotent Stem Cells

Simple Rt-QPCR chip for single marine diatom cells

Shi, X., Gao, W., Chao, S-H. & Meldrum, D., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1924-1926 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gene expression
Polymerase chain reaction
Transcription
Microfluidics
Silica

Single cell metabolic profiling using multiplexed, photo-patterned fluorescence sensor arrays

Song, G., Wang, K. C., Ueberroth, B., Lee, F., Zhang, L., Su, F., Zhu, H., Mei, Q., Chao, S-H., Kelbauskas, L., Tian, Y., Wang, H. & Meldrum, D., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 884-886 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sensor arrays
Fluorescence
Photopolymerization
Acidification
Fused silica
2013
19 Citations (Scopus)

A fluorescent colorimetric pH sensor and the influences of matrices on sensing performances

Tian, Y., Fuller, E., Klug, S., Lee, F., Su, F., Zhang, L., Chao, S-H. & Meldrum, D., 2013, In : Sensors and Actuators, B: Chemical. 188, p. 1-10 10 p.

Research output: Contribution to journalArticle

pH sensors
Color
Polymer matrix
sensors
matrices

Autonomous high throughput real time PCR platform for large scale environmental monitoring

Ray, T., Hatch, A., Lintecum, K., Chao, S-H. & Youngbull, C., 2013, Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013. Vol. 3. p. 85-88 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Environmental Monitoring
Real-Time Polymerase Chain Reaction
Optical Fibers
Polymerase Chain Reaction
Temperature
5 Citations (Scopus)

Microbe observation and cultivation array (MOCA) for cultivating and analyzing environmental microbiota

Gao, W., Navarroli, D., Naimark, J., Zhang, W., Chao, S-H. & Meldrum, D., Jan 9 2013, In : Microbiome. 1, 1, 4.

Research output: Contribution to journalArticle

Microbiota
Observation
Growth
Bacteria
Metagenomics
17 Citations (Scopus)
Diatoms
Bacillariophyceae
Thalassiosira
Reverse Transcription
gene expression
1 Citation (Scopus)

Rotation of cells and cell clusters in culture media for optical computed tomography

Wang, H., Stanley, M., Elango, I. S., Shetty, R. M., Teller, W., Shabilla, A., Limsirichai, P., Zhu, H., Houkal, J., Smith, D., Chao, S-H., Kelbauskas, L., Johnson, R. H. & Meldrum, D., 2013, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, Vol. 2. p. 1090-1092 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoresists
Microfluidics
Tomography
Culture Media
Imaging techniques
2012
5 Citations (Scopus)

Simulation and experimental characterization of microscopically accessible hydrodynamic microvortices

Zhang, W., Frakes, D., Babiker, H., Chao, S-H., Youngbull, C., Johnson, R. H. & Meldrum, D., 2012, In : Micromachines. 3, 2, p. 529-541 13 p.

Research output: Contribution to journalArticle

Hydrodynamics
Imaging techniques
Microfluidics
Microfabrication
Computer simulation
5 Citations (Scopus)

Surface tension-controlled three-dimensional water molds: Theory and applications

Goff, C. M., Chao, S-H., Johnson, R. H. & Meldrum, D., Dec 2012, In : Microfluidics and Nanofluidics. 13, 6, p. 891-897 7 p.

Research output: Contribution to journalArticle

funnels
Molds
Pore size
Surface tension
interfacial tension
2011

Embedding off-the-shelf filter in PDMS chip for microbe sampling

Lécluse, A., Chao, S-H. & Meldrum, D., Aug 2011, In : Microfluidics and Nanofluidics. 11, 2, p. 221-225 5 p.

Research output: Contribution to journalArticle

microorganisms
Polydimethylsiloxane
shelves
embedding
sampling
32 Citations (Scopus)

Real-time PCR of single bacterial cells on an array of adhering droplets

Shi, X., Lin, L. I., Chen, S. Y., Chao, S-H., Zhang, W. & Meldrum, D., Jul 7 2011, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 11, 13, p. 2276-2281 6 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Liquids
Microfluidics
Purification
Oils

Single-cell real-time PCR: Direct process from cells to data

Shi, X., Lin, L. I., Chen, S. Y., Gao, W., Chao, S-H., Zhang, W. & Meldrum, D., 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Vol. 1. p. 362-364 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Costs
2009

Liquid pumping with surface tension-confined microfluidics

Chao, S-H. & Meldrum, D., 2009, Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 61-63 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Surface tension
Liquids

Microscale Oil-Covered Cell Array (MOCCA): A droplet array for high-content single-cell analysis and imaging

Lin, L. I., Chao, S-H. & Meldrum, D., 2009, Proceedings of the 7th International Conference on Nanochannels, Microchannels, and Minichannels 2009, ICNMM2009. PART A ed. p. 669-672 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oils
Imaging techniques
Fabrication
Microfabrication
Escherichia coli
16 Citations (Scopus)

Practical, microfabrication-free device for single-cell isolation

Lin, L. I., Chao, S-H. & Meldrum, D., Aug 21 2009, In : PLoS One. 4, 8, e6710.

Research output: Contribution to journalArticle

Microtechnology
Cell Separation
Microfabrication
Oils
Equipment and Supplies
13 Citations (Scopus)
Surface Tension
Microfluidics
Surface tension
Liquids
2007
1 Citation (Scopus)

Characterization of program controlled CO2 laser-cut PDMS channels for lab-on-a-chip applications

Holle, A. W., Chao, S-H., Holl, M. R., Houkal, J. M. & Meldrum, D., 2007, Proceedings of the 3rd IEEE International Conference on Automation Science and Engineering, IEEE CASE 2007. p. 621-627 7 p. 4341853

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lab-on-a-chip
Polydimethylsiloxane
Lasers
Laser pulses
Chemical operations
1 Citation (Scopus)

Fabrication of lenses with high light-collecting ability using water molds

Chao, S-H., Carlson, R. & Meldrum, D., 2007, Proceedings of the 5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007. p. 809-812 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Molds
Lenses
lenses
Fabrication
fabrication
8 Citations (Scopus)

Phosphorescence lifetime based oxygen microsensing using a digital micromirror device

Chao, S-H., Holl, M. R., McQuaide, S. C., Ren, T. T. H., Gales, S. A. & Meldrum, D., Aug 20 2007, In : Optics Express. 15, 17, p. 10681-10689 9 p.

Research output: Contribution to journalArticle

phosphorescence
life (durability)
light modulation
microscopes
oxygen
47 Citations (Scopus)
Molds
Microchannels
Fungi
Polydimethylsiloxane
Plasmas
17 Citations (Scopus)

Resonant mode-hopping micromixing

Jang, L. S., Chao, S-H., Holl, M. R. & Meldrum, D., Jul 20 2007, In : Sensors and Actuators, A: Physical. 138, 1, p. 179-186 8 p.

Research output: Contribution to journalArticle

Diaphragms
Fluorescein
Flow fields
Topology
Acoustic streaming
1 Citation (Scopus)

Single-cell information extraction and viability analysis using automated microscopy

Chao, S-H., Strovas, T. J., Zhang, S., Jones-Isaac, K. A. & Meldrum, D., 2007, 2006 IEEE International Conference on Automation Science and Engineering, CASE. p. 33-38 6 p. 4120317

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microscopic examination
Dyes
Cells
Macrophages
Microscopes
2006
3 Citations (Scopus)

Automated digital light modulation microscope (DLMM) for living cell array analysis: Pattern recognition and spatial alignment

Chao, S-H., Ren, T. T. H., Gales, S. A., Holl, M. R., McQuaide, S. C. & Meldrum, D., 2006, Proceedings of the First IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, 2006, BioRob 2006. Vol. 2006. p. 977-981 5 p. 1639218

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Light modulation
Pattern recognition
Screening
Microscopes
Cells

High-throughput, long-term imaging of Salmonella infecting macrophages in a micro-environmental system

Chao, S-H., Strovas, T. J., Wang, T. S. M., Jones-Isaac, K. A., Fink, S. L., Cookson, B. T. & Meldrum, D., 2006, Proceedings of the 4th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2006. Vol. 2006 B. p. 1053-1058 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Salmonella
Macrophages
Microscopes
Throughput
Environmental chambers
2 Citations (Scopus)

Liquid crystal thermography of an on-chip polymerase chain reaction micro-thermocycler

Fung, T. H., Chao, S-H., Peach, J. E. & Meldrum, D., 2006, Proceedings of the 4th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2006. Vol. 2006 B. p. 1039-1044 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Polymerase chain reaction
Liquid crystals
Temperature distribution
Temperature control
Temperature measurement
3 Citations (Scopus)

Oxygen concentration measurement with a phosphorescence lifetime based micro-sensor array using a digital light modulation microscope

Chao, S-H., Holl, M. R., McQuaide, S. C. & Meldrum, D., 2006, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6088. 60880S

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Phosphorescence
Light modulation
Sensor arrays
Microscopes
Dyes
1 Citation (Scopus)

Soft lithography without using photolithography

Chao, S-H., Carlson, R. & Meldrum, D., 2006, Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Japan Academic Association Inc, p. 672-674 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photolithography
Lithography
Plasmas
Fabrication
Molds
14 Citations (Scopus)

The design and control of a three-dimensional piezoceramic tube scanner with an inertial slider

Chao, S-H., Garbini, J. L., Dougherty, W. M. & Sidles, J. A., Jul 11 2006, In : Review of Scientific Instruments. 77, 6, 063710.

Research output: Contribution to journalArticle

chutes
scanners
tubes
Velocity control
Dynamic analysis
2005

Lower limits of detection for single biological particles using impedance spectroscopy

Seriburi, P., Shastry, A., Van't Wout, A., Mittler, J., Chao, S-H., Koschwanez, J. & Meldrum, D., 2005, 2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications. p. 17-18 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lab-on-a-chip
Spectroscopy
Membranes
Monitoring
12 Citations (Scopus)

Microfluidic circulatory flows induced by resonant vibration of diaphragms

Jang, L. S., Chao, S-H., Holl, M. R. & Meldrum, D., Jul 29 2005, In : Sensors and Actuators, A: Physical. 122, 1 SPEC. ISS., p. 141-148 8 p.

Research output: Contribution to journalArticle

resonant vibration
diaphragms
Diaphragms
Microfluidics
Acoustic streaming

Scaling for microfluidic mixing

Chao, S-H., Holl, M. R., Koschwanez, J. H., Seriburi, P. & Meldrum, D., 2005, Proceedings of the 3rd International Conference on Microchannels and Minichannels, 2005. Vol. PART B. p. 329-336 8 p. ICMM2005-75236

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Fluids
Stretching
Advection
Time series

Three-dimensional microfluidic flow field characterization with partical image velocimetry and laser scanning confocal microscopy

Chao, S-H., Holl, M. R., Jang, L. S. & Meldrum, D., 2005, Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research Foundation, Vol. 1. p. 109-111 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Confocal microscopy
Microfluidics
Velocity measurement
Flow fields
Acoustic streaming
8 Citations (Scopus)

Velocity measurement in microchannels with a laser confocal microscope and particle linear image velocimetry

Chao, S-H., Holl, M. R., Koschwanez, J. H., Carlson, R. H., Jang, L. S. & Meldrum, D., May 2005, In : Microfluidics and Nanofluidics. 1, 2, p. 155-160 6 p.

Research output: Contribution to journalArticle

microchannels
Microchannels
velocity measurement
Velocity measurement
Microscopes
2004
1 Citation (Scopus)

Microprinting of on-chip cultures: Patterning of yeast cell microarrays using concanavalin-a adhesion

Fung, T. H., Ball, G. I., McQuaide, S. C., Chao, S-H., Colman-Lerner, A., Holl, M. R. & Meldrum, D., 2004, Advances in Bioengineering, BED. American Society of Mechanical Engineers (ASME), p. 373-374 2 p. IMECE2004-60866

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microarrays
Cell culture
Yeast
Adhesion
Cells
38 Citations (Scopus)

Nanometer-scale magnetic resonance imaging

Chao, S-H., Dougherty, W. M., Garbini, J. L. & Sidles, J. A., May 1 2004, In : Review of Scientific Instruments. 75, 5 PART 1, p. 1175-1181 7 p.

Research output: Contribution to journalArticle

Magnetic resonance
magnetic resonance
Microscopic examination
Imaging techniques
Image reconstruction

Velocity measurements in microchannels with a laser scanning microscope and particle linear image velocimetry

Chao, S-H., Holl, M. R., Koschwanez, J. H., Carlson, R. H., Jang, L. S. & Meldrum, D., 2004, Proceedings of the Second International Conference on Microchannels and Minichannels (ICMM2004). Kandlikar, S. G., Celata, G. P., Nishio, S., Stephan, P. & Thonon, B. (eds.). p. 925-930 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microchannels
Velocity measurement
Microscopes
Scanning
Lasers
2003
3 Citations (Scopus)

MEMS modules for life-on-a-chip

Meldrum, D., Holl, M., Seriburi, P., Phillips, S., Chao, S-H., Jang, L. & Kosar, F., 2003, Proceedings - IEEE International Symposium on Circuits and Systems. Vol. 3.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

MEMS
Microsystems
Fluidics
Cells
Spectroscopy
27 Citations (Scopus)

The classical and quantum theory of thermal magnetic noise, with applications in spintronics and quantum microscopy

Sidles, J. A., Garbini, J. L., Dougherty, W. M. & Chao, S-H., Dec 1 2003, In : Proceedings of the IEEE. 91, 5, p. 799-816 18 p.

Research output: Contribution to journalReview article

Magnetoelectronics
Quantum theory
Microscopic examination
Quantum entanglement
Atomic physics
2000
15 Citations (Scopus)

The Bloch Equations in High-Gradient Magnetic Resonance Force Microscopy: Theory and Experiment

Dougherty, W. M., Bruland, K. J., Chao, S-H., Garbini, J. L., Jensen, S. E. & Sidles, J. A., Jan 1 2000, In : Journal of Magnetic Resonance. 143, 1, p. 106-119 14 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Magnetic resonance
Microwaves
Paramagnetic resonance
magnetic resonance
1999
34 Citations (Scopus)

Thermal tuning of a fiber-optic interferometer for maximum sensitivity

Bruland, K. J., Garbini, J. L., Dougherty, W. M., Chao, S-H., Jensen, S. E. & Sidles, J. A., Jan 1 1999, In : Review of Scientific Instruments. 70, 9, p. 3542-3544 3 p.

Research output: Contribution to journalArticle

Interferometers
Fiber optics
fiber optics
Vacuum applications
interferometers
1998
51 Citations (Scopus)

Force-detected magnetic resonance in a field gradient of 250 000 Tesla per meter

Bruland, K. J., Dougherty, W. M., Garbini, J. L., Sidles, J. A. & Chao, S-H., Dec 1 1998, In : Applied Physics Letters. 73, 21, p. 3159-3161 3 p.

Research output: Contribution to journalArticle

magnetic resonance
gradients
magnetic fields
micrometers
electron paramagnetic resonance