Research Output per year
Personal profile
Education/Academic qualification
PHD, Bogazici University
… → 2001
MS, Bogazici University
… → 1997
BS, Bogazici University
… → 1995
Fingerprint Dive into the research topics where Sefika Ozkan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Proteins
Medicine & Life Sciences
Protein Folding
Medicine & Life Sciences
Protein folding
Chemical Compounds
Molecular Dynamics Simulation
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Conformations
Chemical Compounds
Catalytic Domain
Medicine & Life Sciences
Allosteric Regulation
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1998 2018
6
Citations
(Scopus)
Ancient thioredoxins evolved to modern-day stability–function requirement by altering native state ensemble
Modi, T., Huihui, J., Ghosh, K. & Ozkan, S., Jun 19 2018, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1749, 20170184.Research output: Contribution to journal › Article
Thioredoxins
protein
Proteins
proteins
Catalytic Domain
1
Citation
(Scopus)
A novel modelling mechanism of PAEL receptor and GABARAPL2 interaction involved in Parkinson's disease
Dutta, P., Dargahi, L., O'Connell, K. E., Bolia, A., Ozkan, S., Sailer, A. W. & Dev, K. K., Apr 23 2018, In : Neuroscience Letters. 673, p. 12-18 7 p.Research output: Contribution to journal › Article
Endothelin Receptors
Parkinson Disease
Autophagy
Receptor Aggregation
Aminobutyrates
7
Citations
(Scopus)
Biotechnological and protein-engineering implications of ancestral protein resurrection
Risso, V. A., Sanchez-Ruiz, J. M. & Ozkan, S., Aug 1 2018, In : Current Opinion in Structural Biology. 51, p. 106-115 10 p.Research output: Contribution to journal › Review article
Protein Engineering
Proteins
Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs
Butler, B. M., Kazan, I. C., Kumar, A. & Ozkan, S., Nov 1 2018, In : PLoS Computational Biology. 14, 11, e1006626.Research output: Contribution to journal › Article
Disease Susceptibility
Susceptibility
disease resistance
Proteins
Protein
Erratum to: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (Scientific Reports, (2017), 7, 1, (10419), 10.1038/s41598-017-10571-z)
Larrimore, K. E., Kazan, I. C., Kannan, L., Kendle, R. P., Jamal, T., Barcus, M., Bolia, A., Brimijoin, S., Zhan, C. G., Ozkan, S. & Leket-Mor, T., Dec 1 2018, In : Scientific Reports. 8, 1, 17223.Research output: Contribution to journal › Comment/debate
Butyrylcholinesterase
Cholinesterases
Hydrolases
Cocaine
Projects 2010 2022
Deciphering the Second Secret of Life: Discovering and manipulating allostery for enzymatic control
Gordon and Betty Moore Foundation
10/14/19 → 11/30/22
Project: Research project
IIBR RoL: Development of enhanced computational protein design methods using a metaanalysis of enzyme dynamics
National Science Foundation (NSF)
9/1/19 → 8/31/22
Project: Research project
Mapping SequenceStructure Function Landscape by Integrating Evolutionary Landscape Inference with Folding and Dynamics
NSF: Directorate for Biological Sciences (BIO)
8/1/17 → 7/31/20
Project: Research project
Proteins
Binding sites
Peptides
Amino acids
Conservation
Molecular Mechanisms of Secondary Active Transporters
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/1/16 → 3/31/21
Project: Research project
Protons
Antiporters
Cations
Bile Acids and Salts
Ions
New Tools for Glycoscience: Engineering Targeted Lectins by Computer-Guided Directed Evolution
Ghirlanda, G., Ozkan, S. & Wang, X.
HHS: National Institutes of Health (NIH)
8/16/16 → 7/31/19
Project: Research project
Lectins
Polysaccharides
Glycosylation
Biological Phenomena
Proteins