• 11387 Citations
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1976 …2020
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Research Output 1976 2019

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Article
2019

How evolutionary psychiatry can advance psychopharmacology


Nesse, R. M. & Stein, D. J., Jan 1 2019, In : Dialogues in clinical neuroscience. 21, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

Psychopharmacology
Psychiatry
Frustration
Genetic Selection
Neurosciences
1 Citation (Scopus)

The state of evolutionary medicine in undergraduate education

Grunspan, D. Z., Moeller, K. T., Nesse, R. M. & Brownell, S. E., Jan 21 2019, In : Evolution, Medicine and Public Health. 2019, 1, p. 82-92 11 p.

Research output: Contribution to journalArticle

Open Access
State Medicine
college students
medicine
education
Medicine
2018
5 Citations (Scopus)

Core principles of evolutionary medicine: A Delphi study

Grunspan, D. Z., Nesse, R., Barnes, M. E. & Brownell, S., Jan 1 2018, In : Evolution, Medicine and Public Health. 2018, 1, p. 13-23 11 p.

Research output: Contribution to journalArticle

Delphi Technique
medicine
Medicine
evolutionary biology
teachers
2017
11 Citations (Scopus)

Teleological reasoning, not acceptance of evolution, impacts students' ability to learn natural selection

Barnes, M. E., Evans, E. M., Hazel, A., Brownell, S. & Nesse, R., Oct 2 2017, In : Evolution: Education and Outreach. 10, 1, 7.

Research output: Contribution to journalArticle

Open Access
natural selection
students
student
acceptance
ability
2016
1 Citation (Scopus)

Human compulsivity: A perspective from evolutionary medicine

Stein, D. J., Hermesh, H., Eilam, D., Segalas, C., Zohar, J., Menchon, J. & Nesse, R., May 1 2016, In : European Neuropsychopharmacology. 26, 5, p. 869-876 8 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Medicine
Behavioral Symptoms
Neurobiology
1 Citation (Scopus)

Social selection is a powerful explanation for prosociality

Nesse, R., 2016, In : Behavioral and Brain Sciences. 39, p. e47

Research output: Contribution to journalArticle

Homeless Youth
union and employers' representatives
reciprocity
Group
Group Selection
143 Citations (Scopus)

What are 'good' depression symptoms? Comparing the centrality of DSM and non-DSM symptoms of depression in a network analysis

Fried, E. I., Epskamp, S., Nesse, R., Tuerlinckx, F. & Borsboom, D., Jan 1 2016, In : Journal of Affective Disorders. 189, p. 314-320 7 p.

Research output: Contribution to journalArticle

Depression
Psychometrics
Psychiatry
Outpatients
Therapeutics
2015
18 Citations (Scopus)

Commentary: "Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression"

Fried, E. I., Boschloo, L., van Borkulo, C. D., Schoevers, R. A., Romeijn, J. W., Wichers, M., de Jonge, P., Nesse, R., Tuerlinckx, F. & Borsboom, D., 2015, In : Frontiers in Psychiatry. 6, AUG, 117.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Antidepressive Agents
Placebos
Depression
165 Citations (Scopus)

Depression is not a consistent syndrome: An investigation of unique symptom patterns in the STAR∗D study

Fried, E. I. & Nesse, R., 2015, In : Journal of Affective Disorders. 172, p. 96-102 7 p.

Research output: Contribution to journalArticle

Depression
Major Depressive Disorder
Therapeutics
Outpatients
173 Citations (Scopus)

Depression sum-scores don't add up: Why analyzing specific depression symptoms is essential

Fried, E. I. & Nesse, R., Apr 6 2015, In : BMC Medicine. 13, 1, 72.

Research output: Contribution to journalArticle

Depression
Suicidal Ideation
Sleep Initiation and Maintenance Disorders
Research
Antidepressive Agents
10 Citations (Scopus)

Normal and Abnormal Anxiety in the Age of DSM-5 and ICD-11

Stein, D. J. & Nesse, R., Jul 11 2015, In : Emotion Review. 7, 3, p. 223-229 7 p.

Research output: Contribution to journalArticle

Emotions
Anxiety
Anxiety Disorders
Psychotherapy
Public Health
33 Citations (Scopus)

The differential influence of life stress on individual symptoms of depression

Fried, E. I., Nesse, R., Guille, C. & Sen, S., Jun 1 2015, In : Acta Psychiatrica Scandinavica. 131, 6, p. 465-471 7 p.

Research output: Contribution to journalArticle

Psychological Stress
Depression
Suicidal Ideation
Major Depressive Disorder
Internship and Residency
6 Citations (Scopus)

The status of evolutionary medicine education in North American medical schools

Hidaka, B. H., Asghar, A., Aktipis, C. A., Nesse, R. M., Wolpaw, T. M., Skursky, N. K., Bennett, K. J., Beyrouty, M. W. & Schwartz, M. D., 2015, In : BMC Medical Education. 15, p. 38 1 p.

Research output: Contribution to journalArticle

Medical Schools
Curriculum
Medicine
medicine
Education
2014
5 Citations (Scopus)

Comment: A general "theory of emotion" is neither necessary nor possible

Nesse, R., Oct 27 2014, In : Emotion Review. 6, 4, p. 320-322 3 p.

Research output: Contribution to journalArticle

Emotions
Genetic Selection
Emotion
General Theory
Research
81 Citations (Scopus)

Depression is more than the sum score of its parts: Individual DSM symptoms have different risk factors

Fried, E. I., Nesse, R., Zivin, K., Guille, C. & Sen, S., 2014, In : Psychological Medicine. 44, 10, p. 2067-2076 10 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Depression
Internship and Residency
Longitudinal Studies
Health
3 Citations (Scopus)
Widowhood
Spouses
spouse
wisdom
wedding
101 Citations (Scopus)

The impact of individual depressive symptoms on impairment of psychosocial functioning

Fried, E. I. & Nesse, R., Feb 28 2014, In : PLoS One. 9, 2, e90311.

Research output: Contribution to journalArticle

signs and symptoms (animals and humans)
Depression
Disorders of Excessive Somnolence
Major Depressive Disorder
emotions
2013
77 Citations (Scopus)

Evolutionary foundations for cancer biology

Aktipis, C. A. & Nesse, R., Jan 2013, In : Evolutionary Applications. 6, 1, p. 144-159 16 p.

Research output: Contribution to journalArticle

cancer
Biological Sciences
neoplasms
Neoplasms
natural selection
38 Citations (Scopus)

Tinbergen's four questions, organized: A response to Bateson and Laland

Nesse, R., Dec 2013, In : Trends in Ecology and Evolution. 28, 12, p. 681-682 2 p.

Research output: Contribution to journalArticle

Famous Persons
Animal Behavior
animal behavior
animal
animals
2012
21 Citations (Scopus)

Evolution and medicine in undergraduate education: A prescription for all biology students

Antolin, M. F., Jenkins, K. P., Bergstrom, C. T., Crespi, B. J., De, S., Hancock, A., Hanley, K. A., Meagher, T. R., Moreno-Estrada, A., Nesse, R., Omenn, G. S. & Stearns, S. C., Jun 2012, In : Evolution. 66, 6, p. 1991-2006 16 p.

Research output: Contribution to journalArticle

college students
medicine
Prescriptions
education
students
25 Citations (Scopus)

Evolutionary molecular medicine

Nesse, R., Ganten, D., Gregory, T. R. & Omenn, G. S., May 2012, In : Journal of Molecular Medicine. 90, 5, p. 509-522 14 p.

Research output: Contribution to journalArticle

Molecular Medicine
Medicine
Population Genetics
Phylogeny
Genomics

Re: Evolutionary explanations for patients

Nesse, R., May 2012, In : Canadian Journal of Psychiatry. 57, 5, p. 338 1 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
Biological Evolution
Molecular Medicine
Modern 1601-history
Genomics
Public Health
77 Citations (Scopus)

Towards a genuinely medical model for psychiatric nosology

Nesse, R. & Stein, D. J., Jan 13 2012, In : BMC Medicine. 10, 5.

Research output: Contribution to journalArticle

Psychiatry
Biomarkers
Cough
Mental Disorders
Comorbidity
2011
8 Citations (Scopus)

Evolutionary approaches to sexually transmitted infections

Nesse, R. & Foxman, B., Aug 2011, In : Annals of the New York Academy of Sciences. 1230, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

Pathogens
Sexually Transmitted Diseases
Phylogeny
Medicine
Disease Outbreaks
31 Citations (Scopus)

Ten questions for evolutionary studies of disease vulnerability

Nesse, R., Mar 2011, In : Evolutionary Applications. 4, 2, p. 264-277 14 p.

Research output: Contribution to journalArticle

medicine
vulnerability
Medicine
Population Genetics
population genetics
25 Citations (Scopus)

Threat detection, precautionary responses, and anxiety disorders

Stein, D. J. & Nesse, R., Mar 2011, In : Neuroscience and Biobehavioral Reviews. 35, 4, p. 1075-1079 5 p.

Research output: Contribution to journalArticle

Anxiety Disorders
Research
Psychiatry
Psychology
Cognitive Neuroscience
9 Citations (Scopus)

Why has natural selection left us so vulnerable to anxiety and mood disorders?

Nesse, R., Dec 2011, In : Canadian Journal of Psychiatry. 56, 12, p. 705-706 2 p.

Research output: Contribution to journalArticle

Biological Evolution
Genetic Selection
Anxiety Disorders
Mood Disorders
2010

Author's reply

Nesse, R., Mar 2010, In : British Journal of Psychiatry. 196, 3, p. 247-248 2 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Evolutionary perspectives on health and medicine

Stearns, S. C., Nesse, R., Govindaraju, D. R. & Ellison, P. T., Jan 26 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, SUPPL. 1, p. 1691-1695 5 p.

Research output: Contribution to journalArticle

Chromosome Aberrations
Public Health
Medicine
Mutation
Health

Introducing Evolutionary Thinking For Medicine

Stearns, S. C., Nesse, R. & Haig, D., Apr 1 2010, In : Unknown Journal.

Research output: Contribution to journalArticle

Genetic Selection
Pathogens
Medicine
natural selection
medicine
117 Citations (Scopus)

Making evolutionary biology a basic science for medicine

Nesse, R., Bergstrom, C. T., Ellison, P. T., Flier, J. S., Gluckman, P., Govindaraju, D. R., Niethammer, D., Omenn, G. S., Perlman, R. L., Schwartz, M. D., Thomas, M. G., Stearns, S. C. & Valle, D., Jan 26 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, SUPPL. 1, p. 1800-1807 8 p.

Research output: Contribution to journalArticle

Medicine
Physicians
Medical Schools
Premedical Students
Molecular Evolution
2009
163 Citations (Scopus)

Evolution, Emotions, and Emotional Disorders

Nesse, R. & Ellsworth, P. C., Feb 2009, In : American Psychologist. 64, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Emotions
Genetic Selection
Aptitude
Research
11 Citations (Scopus)

Evolution at 150: Time for truly biological psychiatry

Nesse, R., 2009, In : British Journal of Psychiatry. 195, 6, p. 471-472 2 p.

Research output: Contribution to journalArticle

Biological Psychiatry
2008
39 Citations (Scopus)

Antidepressant use in black and white populations in the United States

González, H. M., Croghan, T., West, B., Williams, D., Nesse, R., Tarraf, W., Taylor, R., Hinton, L., Neighbors, H. & Jackson, J., Oct 2008, In : Psychiatric Services. 59, 10, p. 1131-1138 8 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Depressive Disorder
Anxiety Disorders
Population
Vascular Diseases
2 Citations (Scopus)

Darwin 200: Great expectations

Akyol, M., Greaves, M., Eldredge, N., Persson, P. E., Gowaty, P. A., Nei, M., Lynch, M., Kutschera, U., Nesse, R. & Serageldin, I., Nov 20 2008, In : Nature. 456, 7220, p. 317-318 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Vomiting is not an adaption for glaucoma (and Darwinian medicine is difficult)

Paşca, S. P. & Nesse, R., Sep 2008, In : Medical Hypotheses. 71, 3, p. 472-473 2 p.

Research output: Contribution to journalArticle

Physiological Adaptation
Angle Closure Glaucoma
Biological Models
Intraocular Pressure
Glaucoma
8 Citations (Scopus)

What evolutionary biology offers public health

Nesse, R., Feb 2008, In : Bulletin of the World Health Organization. 86, 2, p. 83 1 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Health Policy
Health Promotion
Disease Outbreaks
Public Health
2007
5 Citations (Scopus)

Evolution is the scientific foundation for diagnosis: Psychiatry should use it

Nesse, R., Oct 2007, In : World Psychiatry. 6, 3, p. 160-161 2 p.

Research output: Contribution to journalArticle

Psychiatry
656 Citations (Scopus)

Prevalence and distribution of major depressive disorder in African Americans, Caribbean blacks, and non-Hispanic whites: Results from the National Survey of American Life

Williams, D. R., González, H. M., Neighbors, H., Nesse, R., Abelson, J. M., Sweetman, J. & Jackson, J. S., Mar 2007, In : Archives of General Psychiatry. 64, 3, p. 305-315 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
African Americans
Depression
Sampling Studies
Surveys and Questionnaires
197 Citations (Scopus)

Race, ethnicity, and the use of services for mental disorders: Results from the National Survey of American Life

Neighbors, H. W., Caldwell, C., Williams, D. R., Nesse, R., Taylor, R. J., Bullard, K. M., Torres, M. & Jackson, J. S., Apr 2007, In : Archives of General Psychiatry. 64, 4, p. 485-494 10 p.

Research output: Contribution to journalArticle

Mental Disorders
African Americans
Mental Health
Mental Health Services
Complementary Therapies
55 Citations (Scopus)

Unfair treatment and self-regulatory focus

Oyserman, D., Uskul, A. K., Yoder, N., Nesse, R. & Williams, D. R., May 2007, In : Journal of Experimental Social Psychology. 43, 3, p. 505-512 8 p.

Research output: Contribution to journalArticle

Therapeutics
Head
Students
job situation
promotion
2006
102 Citations (Scopus)

An evolutionary life-history framework for understanding sex differences in human mortality rates

Kruger, D. J. & Nesse, R., 2006, In : Human Nature. 17, 1, p. 74-97 24 p.

Research output: Contribution to journalArticle

gender differences
life history
mortality
cause
sexual selection
9 Citations (Scopus)

Darwinian medicine and mental disorders

Nesse, R., Jun 2006, In : International Congress Series. 1296, p. 83-94 12 p.

Research output: Contribution to journalArticle

Mental Disorders
Medicine
Emotions
Genetic Selection
Psychiatry
13 Citations (Scopus)

Evolution: Psychiatric nosology's missing biological foundation

Nesse, R. & Jackson, E. D., Apr 2006, In : Clinical Neuropsychiatry. 3, 2, p. 121-131 11 p.

Research output: Contribution to journalArticle

Psychiatry
Emotions
Brain
Cough
Mental Disorders
63 Citations (Scopus)

Medicine needs evolution

Nesse, R., Stearns, S. C. & Omenn, G. S., Feb 24 2006, In : Science. 311, 5764, p. 1071 1 p.

Research output: Contribution to journalArticle

Biological Science Disciplines
Medical Education
Medicine
80 Citations (Scopus)

Older adults' perceptions of intergenerational support after widowhood how do men and women differ?

Ha, J. H., Carr, D., Utz, R. L. & Nesse, R., Jan 2006, In : Journal of Family Issues. 27, 1, p. 3-30 28 p.

Research output: Contribution to journalArticle

legal advice
widower
parents
widow
married couple
115 Citations (Scopus)
Depression
Crying
Guilt
Genetic Selection
pessimism
2005
16 Citations (Scopus)

Association between a dopamine-4 receptor polymorphism and blood pressure

Sen, S., Nesse, R., Sheng, L., Stoltenberg, S. F., Gleiberman, L., Burmeister, M. & Weder, A. B., Sep 2005, In : American Journal of Hypertension. 18, 9, p. 1206-1210 5 p.

Research output: Contribution to journalArticle

Dopamine Receptors
Blood Pressure
Alleles
Hypertension
Dopamine
88 Citations (Scopus)

Is low mood an adaptation? Evidence for subtypes with symptoms that match precipitants

Keller, M. C. & Nesse, R., May 2005, In : Journal of Affective Disorders. 86, 1, p. 27-35 9 p.

Research output: Contribution to journalArticle

Genetic Selection
Depression
Crying
Social Isolation
Arousal