• 15184 Citations
  • 55 h-Index
1986 …2022
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Research Output 1986 2019

2012
29 Citations (Scopus)

Improving the accuracy of macromolecular structure refinement at 7 Å resolution

Brunger, A. T., Adams, P. D., Fromme, P., Fromme, R., Levitt, M. & Schröder, G. F., Jun 6 2012, In : Structure. 20, 6, p. 957-966 10 p.

Research output: Contribution to journalArticle

Photosystem I Protein Complex
Synchrotrons
X Ray Crystallography
Electrons
125 Citations (Scopus)

In vivo protein crystallization opens new routes in structural biology

Koopmann, R., Cupelli, K., Redecke, L., Nass, K., Deponte, D. P., White, T. A., Stellato, F., Rehders, D., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M. J., Bostedt, C., Boutet, S., Bozek, J. D., Caleman, C., Coppola, N. & 49 others, Davidsson, J., Doak, R. B., Ekeberg, T., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, A., Hartmann, R., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Kassemeyer, S., Kirian, R., Lomb, L., Maia, F. R. N. C., Kimmel, N., Martin, A. V., Messerschmidt, M., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M. M., Shoeman, R. L., Sierra, R. G., Soltau, H., Stern, S., Strülder, L., Timneanu, N., Ullrich, J., Wang, X., Weidenspointner, G., Weierstall, U., Williams, G. J., Wunderer, C. B., Fromme, P., Spence, J., Stehle, T., Chapman, H. N., Betzel, C. & Duszenko, M., Mar 2012, In : Nature Methods. 9, 3, p. 259-262 4 p.

Research output: Contribution to journalArticle

Trypanosoma brucei brucei
Crystallography
Systems Biology
Crystallization
Lasers
120 Citations (Scopus)

Lipidic phase membrane protein serial femtosecond crystallography

Johansson, L. C., Arnlund, D., White, T. A., Katona, G., Deponte, D. P., Weierstall, U., Doak, R. B., Shoeman, R. L., Lomb, L., Malmerberg, E., Davidsson, J., Nass, K., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M. J., Bostedt, C. & 48 others, Bozek, J. D., Caleman, C., Coffee, R., Coppola, N., Ekeberg, T., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Kassemeyer, S., Kimmel, N., Kirian, R., Maia, F. R. N. C., Marchesini, S., Martin, A. V., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M. M., Sierra, R. G., Soltau, H., Starodub, D., Stellato, F., Stern, S., Strülder, L., Timneanu, N., Ullrich, J., Wahlgren, W. Y., Wang, X., Weidenspointner, G., Wunderer, C., Fromme, P., Chapman, H. N., Spence, J. & Neutze, R., Mar 2012, In : Nature Methods. 9, 3, p. 263-265 3 p.

Research output: Contribution to journalArticle

X ray lasers
Crystallography
Free electron lasers
Porifera
Membrane Proteins
236 Citations (Scopus)

Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements

Barty, A., Caleman, C., Aquila, A., Timneanu, N., Lomb, L., White, T. A., Andreasson, J., Arnlund, D., Bajt, S., Barends, T. R. M., Barthelmess, M., Bogan, M. J., Bostedt, C., Bozek, J. D., Coffee, R., Coppola, N., Davidsson, J., Deponte, D. P., Doak, R. B., Ekeberg, T. & 48 others, Elser, V., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Fromme, P., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Johansson, L., Kassemeyer, S., Kimmel, N., Kirian, R., Liang, M., Maia, F. R. N. C., Malmerberg, E., Marchesini, S., Martin, A. V., Nass, K., Neutze, R., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Scott, H., Schlichting, I., Schulz, J., Marvin Seibert, M., Shoeman, R. L., Sierra, R. G., Soltau, H., Spence, J., Stellato, F., Stern, S., Strüder, L., Ullrich, J., Wang, X., Weidenspointner, G., Weierstall, U., Wunderer, C. B. & Chapman, H. N., Jan 2012, In : Nature Photonics. 6, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

X ray lasers
Free electron lasers
stopping
Diffraction
Crystalline materials
3 Citations (Scopus)

Size based nanoparticle separation using dielectrophoretic focusing for femtosecond nanocrystallography of membrane proteins

Abdallah, B., Chao, T. C., Fromme, P. & Ros, A., 2012, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 458-460 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sorting
Membrane Proteins
Nanoparticles
Electrophoresis
Proteins
148 Citations (Scopus)

Time-resolved protein nanocrystallography using an X-ray free-electron laser

Aquila, A., Hunter, M. S., Doak, R. B., Kirian, R., Fromme, P., White, T. A., Andreasson, J., Arnlund, D., Bajt, S., Barends, T. R. M., Barthelmess, M., Bogan, M. J., Bostedt, C., Bottin, H., Bozek, J. D., Caleman, C., Coppola, N., Davidsson, J., Deponte, D. P., Elser, V. & 59 others, Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Frank, M., Fromme, R., Graafsma, H., Grotjohann, I., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, A., Hartmann, R., Hau-Riege, S., Hauser, G., Hirsemann, H., Holl, P., Holton, J. M., Hömke, A., Johansson, L., Kimmel, N., Kassemeyer, S., Krasniqi, F., Kühnel, K. U., Liang, M., Lomb, L., Malmerberg, E., Marchesini, S., Martin, A. V., Maia, F. R. N. C., Messerschmidt, M., Nass, K., Reich, C., Neutze, R., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schmidt, C., Schmidt, K., Schulz, J., Marvin Seibert, M., Shoeman, R. L., Sierra, R., Soltau, H., Starodub, D., Stellato, F., Stern, S., Strüder, L., Timneanu, N., Ullrich, J., Wang, X., Williams, G. J., Weidenspointner, G., Weierstall, U., Wunderer, C., Barty, A., Spence, J. & Chapman, H. N., Jan 30 2012, In : Optics Express. 20, 3, p. 2706-2716 11 p.

Research output: Contribution to journalArticle

free electron lasers
proteins
electron transfer
crystals
x rays
2013
50 Citations (Scopus)

Coordinating the impact of structural genomics on the human α-helical transmembrane proteome

Pieper, U., Schlessinger, A., Kloppmann, E., Chang, G. A., Chou, J. J., Dumont, M. E., Fox, B. G., Fromme, P., Hendrickson, W. A., Malkowski, M. G., Rees, D. C., Stokes, D. L., Stowell, M. H. B., Wiener, M. C., Rost, B., Stroud, R. M., Stevens, R. C. & Sali, A., Feb 2013, In : Nature Structural and Molecular Biology. 20, 2, p. 135-138 4 p.

Research output: Contribution to journalArticle

Proteome
Genomics
Membrane Proteins
Membranes
3 Citations (Scopus)

Crystallization of a self-assembled three-dimensional DNA nanostructure

Rendek, K. N., Fromme, R., Grotjohann, I. & Fromme, P., Feb 2013, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 69, 2, p. 141-146 6 p.

Research output: Contribution to journalArticle

Nanostructures
Crystallization
tetrahedrons
deoxyribonucleic acid
crystallization
13 Citations (Scopus)

Crystallization of the large membrane protein complex photosystem i in a microfluidic channel

Abdallah, B. G., Kupitz, C., Fromme, P. & Ros, A., Dec 23 2013, In : ACS Nano. 7, 12, p. 10534-10543 10 p.

Research output: Contribution to journalArticle

Crystallization
Microfluidics
Membrane Proteins
crystallization
membranes
33 Citations (Scopus)

Dielectrophoretic sorting of membrane protein nanocrystals

Abdallah, B. G., Chao, T. C., Kupitz, C., Fromme, P. & Ros, A., Oct 22 2013, In : ACS Nano. 7, 10, p. 9129-9137 9 p.

Research output: Contribution to journalArticle

classifying
Sorting
Nanocrystals
nanocrystals
Membrane Proteins
Electron injection
Photosynthesis
Productivity
Electricity
Microorganisms

High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane.

Zook, J. D., Molugu, T. R., Jacobsen, N. E., Lin, G., Soll, J., Cherry, B., Brown, M. F. & Fromme, P., 2013, In : PLoS One. 8, 10, e78116.

Research output: Contribution to journalArticle

amino acid transporters
Amino Acid Transport Systems
Chloroplasts
chloroplasts
Nuclear magnetic resonance
299 Citations (Scopus)

Natively inhibited trypanosoma brucei cathepsin B structure determined by using an x-ray laser

Redecke, L., Nass, K., DePonte, D. P., White, T. A., Rehders, D., Barty, A., Stellato, F., Liang, M., Barends, T. R. M., Boutet, S., Williams, G. J., Messerschmidt, M., Seibert, M. M., Aquila, A., Arnlund, D., Bajt, S., Barth, T. B., Bogan, M. J., Caleman, C., Chao, T. C. & 29 others, Doak, R. B., Fleckenstein, H., Frank, M., Fromme, R., Galli, L., Grotjohann, I., Hunter, M. S., Johansson, L. C., Kassemeyer, S., Katona, G., Kirian, R., Koopmann, R., Kupitz, C., Lomb, L., Martin, A. V., Mogk, S., Neutze, R., Shoeman, R. L., Steinbrener, J., Timneanu, N., Wang, D., Weierstall, U., Zatsepin, N., Spence, J., Fromme, P., Schlichting, I., Duszenko, M., Betzel, C. & Chapman, H. N., Jan 11 2013, In : Science. 339, 6116, p. 227-230 4 p.

Research output: Contribution to journalArticle

Cathepsin B
Trypanosoma brucei brucei
Cysteine Proteases
Lasers
X-Rays

Photosystem I

Grotjohann, I. & Fromme, P., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 503-507 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Photosystem I Protein Complex
Electrons
Cytochromes c6
Photosynthetic membranes
Membrane Proteins
24 Citations (Scopus)

PNA-peptide assembly in a 3D DNA nanocage at room temperature

Flory, J. D., Shinde, S., Lin, S., Liu, Y., Yan, H., Ghirlanda, G. & Fromme, P., May 8 2013, In : Journal of the American Chemical Society. 135, 18, p. 6985-6993 9 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
Peptides
DNA
Temperature
Polypeptides
280 Citations (Scopus)

Serial femtosecond crystallography of G protein-coupled receptors

Liu, W., Wacker, D., Gati, C., Han, G. W., James, D., Wang, D., Nelson, G., Weierstall, U., Katritch, V., Barty, A., Zatsepin, N., Li, D., Messerschmidt, M., Boutet, S., Williams, G. J., Koglin, J. E., Seibert, M. M., Wang, C., Shah, S. T. A., Basu, S. & 13 others, Fromme, R., Kupitz, C., Rendek, K. N., Grotjohann, I., Fromme, P., Kirian, R., Beyerlein, K. R., White, T. A., Chapman, H. N., Caffrey, M., Spence, J., Stevens, R. C. & Cherezov, V., 2013, In : Science. 342, 6165, p. 1521-1524 4 p.

Research output: Contribution to journalArticle

Protein
Laser
Damage
Temperature
Radiation
65 Citations (Scopus)

Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography

Johansson, L. C., Arnlund, D., Katona, G., White, T. A., Barty, A., Deponte, D. P., Shoeman, R. L., Wickstrand, C., Sharma, A., Williams, G. J., Aquila, A., Bogan, M. J., Caleman, C., Davidsson, J., Doak, R. B., Frank, M., Fromme, R., Galli, L., Grotjohann, I., Hunter, M. S. & 25 others, Kassemeyer, S., Kirian, R., Kupitz, C., Liang, M., Lomb, L., Malmerberg, E., Martin, A. V., Messerschmidt, M., Nass, K., Redecke, L., Seibert, M. M., Sjöhamn, J., Steinbrener, J., Stellato, F., Wang, D., Wahlgren, W. Y., Weierstall, U., Westenhoff, S., Zatsepin, N., Boutet, S., Spence, J., Schlichting, I., Chapman, H. N., Fromme, P. & Neutze, R., Dec 19 2013, In : Nature Communications. 4, 2911.

Research output: Contribution to journalArticle

Photosynthetic Reaction Center Complex Proteins
Crystallography
Microcrystals
X Ray Crystallography
X-Ray Diffraction
2014
9 Citations (Scopus)

Draft genome sequence of the filamentous cyanobacterium Leptolyngbya sp. strain Heron Island J, exhibiting chromatic acclimation

Paul, R., Jinkerson, R. E., Buss, K., Steel, J., Mohr, R., Hess, W. R., Chen, M. & Fromme, P., 2014, In : Genome Announcements. 2, 1, e01166-13.

Research output: Contribution to journalArticle

Acclimatization
Cyanobacteria
Islands
Color
Axenic Culture
5 Citations (Scopus)

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

Lee, H. H., Cherni, I., Yu, H., Fromme, R., Doran, J. D., Grotjohann, I., Mittman, M., Basu, S., Deb, A., Dörner, K., Aquila, A., Barty, A., Boutet, S., Chapman, H. N., Doak, R. B., Hunter, M. S., James, D., Kirian, R., Kupitz, C., Lawrence, R. M. & 17 others, Liu, H., Nass, K., Schlichting, I., Schmidt, K., Seibert, M. M., Shoeman, R. L., Spence, J., Stellato, F., Weierstall, U., Williams, G. J., Yoon, C., Wang, D., Zatsepin, N., Hogue, B., Matoba, N., Fromme, P. & Leket-Mor, T., Aug 29 2014, In : IUCrJ. 1, p. 305-317 13 p.

Research output: Contribution to journalArticle

vaccines
human immunodeficiency virus
Vaccines
Crystallization
Viruses
4 Citations (Scopus)

Leading-edge lasers

Fromme, P., 2014, In : Nature. 505, 7485, p. 620-621 2 p.

Research output: Contribution to journalArticle

296 Citations (Scopus)

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Weierstall, U., James, D., Wang, C., White, T. A., Wang, D., Liu, W., Spence, J., Bruce Doak, R., Nelson, G., Fromme, P., Fromme, R., Grotjohann, I., Kupitz, C., Zatsepin, N., Liu, H., Basu, S., Wacker, D., Won Han, G., Katritch, V., Boutet, S. & 17 others, Messerschmidt, M., Williams, G. J., Koglin, J. E., Marvin Seibert, M., Klinker, M., Gati, C., Shoeman, R. L., Barty, A., Chapman, H. N., Kirian, R., Beyerlein, K. R., Stevens, R. C., Li, D., Shah, S. T. A., Howe, N., Caffrey, M. & Cherezov, V., Feb 14 2014, In : Nature Communications. 5, 3309.

Research output: Contribution to journalArticle

Crystallography
injectors
crystallography
Membrane Proteins
membranes
21 Citations (Scopus)

Low temperature assembly of functional 3D DNA-PNA-protein complexes

Flory, J. D., Simmons, C. R., Lin, S., Johnson, T., Andreoni, A., Zook, J., Ghirlanda, G., Liu, Y., Yan, H. & Fromme, P., Jun 11 2014, In : Journal of the American Chemical Society. 136, 23, p. 8283-8295 13 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
DNA
Proteins
Temperature
Azurin
Photosynthesis
Electricity
Microorganisms
Photons
Photobioreactors
37 Citations (Scopus)

Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system

Kupitz, C., Grotjohann, I., Conrad, C. E., Roy-Chowdhury, S., Fromme, R. & Fromme, P., Jul 17 2014, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1647, 20130316.

Research output: Contribution to journalArticle

Thermosynechococcus elongatus
crystallography
Crystallography
Microcrystals
Photosystem II Protein Complex
9 Citations (Scopus)

Probing the nature of charge transfer at nano-bio interfaces: Peptides on metal oxide nanoparticles

Pilarisetty, T., Palma, J. L., Holland, G. P., Fromme, P., Yarger, J. & Mujica, V., Oct 16 2014, In : Journal of Physical Chemistry Letters. 5, 20, p. 3555-3559 5 p.

Research output: Contribution to journalArticle

Oxides
Peptides
peptides
metal oxides
Photosystem I Protein Complex
2 Citations (Scopus)

Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage

Flory, J. D., Johnson, T., Simmons, C. R., Lin, S., Ghirlanda, G. & Fromme, P., 2014, In : Artificial DNA, PNA & XNA. 5, 3, p. 1-8 8 p.

Research output: Contribution to journalArticle

Purification
DNA
Coloring Agents
Electrophoresis
Peptides

Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage

Flory, J. D., Johnson, T., Simmons, C. D., Lin, S., Ghirlanda, G. & Fromme, P., Dec 15 2014, In : Artificial DNA, PNA & XNA. 5, 3, p. e992181

Research output: Contribution to journalArticle

Purification
DNA
Coloring Agents
Electrophoresis
Peptides
7 Citations (Scopus)

Purification and biophysical characterization of the CapA membrane protein FTT0807 from francisella tularensis

Martin-Garcia, J. M., Hansen, D., Zook, J., Loskutov, A. V., Robida, M. D., Craciunescu, F. M., Sykes, K. F., Wachter, R., Fromme, P. & Allen, J., Apr 1 2014, In : Biochemistry. 53, 12, p. 1958-1970 13 p.

Research output: Contribution to journalArticle

Francisella tularensis
Purification
Membrane Proteins
Green Fluorescent Proteins
Ionic strength
3 Citations (Scopus)

Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41

Gong, Z., Kessans, S. A., Song, L., Dörner, K., Lee, H. H., Meador, L. R., LaBaer, J., Hogue, B., Leket-Mor, T. & Fromme, P., Nov 1 2014, In : Protein Science. 23, 11, p. 1607-1618 12 p.

Research output: Contribution to journalArticle

Purification
HIV-1
Membranes
Neutralizing Antibodies
Glycoproteins
267 Citations (Scopus)

Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser

Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K. N., Hunter, M. S., Shoeman, R. L., White, T. A., Wang, D., James, D., Yang, J. H., Cobb, D. E., Reeder, B., Sierra, R. G., Liu, H., Barty, A., Aquila, A. L., Deponte, D., Kirian, R. & 39 others, Bari, S., Bergkamp, J. J., Beyerlein, K. R., Bogan, M. J., Caleman, C., Chao, T. C., Conrad, C. E., Davis, K. M., Fleckenstein, H., Galli, L., Hau-Riege, S. P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A. V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T., Moore, A., Pushkar, Y., Williams, G. J., Boutet, S., Doak, R. B., Weierstall, U., Frank, M., Chapman, H. N., Spence, J. & Fromme, P., Sep 11 2014, In : Nature. 513, 7517, p. 261-265 5 p.

Research output: Contribution to journalArticle

Crystallography
Photosystem II Protein Complex
Lasers
X-Rays
Photosynthesis
170 Citations (Scopus)

Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography

Zhang, H., Unal, H., Gati, C., Han, G. W., Liu, W., Zatsepin, N., James, D., Wang, D., Nelson, G., Weierstall, U., Sawaya, M. R., Xu, Q., Messerschmidt, M., Williams, G. J., Boutet, S., Yefanov, O. M., White, T. A., Wang, C., Ishchenko, A., Tirupula, K. C. & 8 others, Desnoyer, R., Coe, J., Conrad, C. E., Fromme, P., Stevens, R. C., Katritch, V., Karnik, S. S. & Cherezov, V., Nov 6 2014, (Accepted/In press) In : Cell.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Crystallography
Angiotensin Receptors
Antihypertensive Agents
Angiotensin II Type 1 Receptor Blockers
219 Citations (Scopus)

Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

Tenboer, J., Basu, S., Zatsepin, N., Pande, K., Milathianaki, D., Frank, M., Hunter, M., Boutet, S., Williams, G. J., Koglin, J. E., Oberthuer, D., Heymann, M., Kupitz, C., Conrad, C., Coe, J., Roy-Chowdhury, S., Weierstall, U., James, D., Wang, D., Grant, T. & 16 others, Barty, A., Yefanov, O., Scales, J., Gati, C., Seuring, C., Srajer, V., Henning, R., Schwander, P., Fromme, R., Ourmazd, A., Moffat, K., Van Thor, J. J., Spence, J., Fromme, P., Chapman, H. N. & Schmidt, M., Dec 5 2014, In : Science. 346, 6214, p. 1242-1246 5 p.

Research output: Contribution to journalArticle

Crystallography
Electrons
Light
Bacterial Proteins
Proteins
107 Citations (Scopus)

Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser

Arnlund, D., Johansson, L. C., Wickstrand, C., Barty, A., Williams, G. J., Malmerberg, E., Davidsson, J., Milathianaki, D., DePonte, D. P., Shoeman, R. L., Wang, D., James, D., Katona, G., Westenhoff, S., White, T. A., Aquila, A., Bari, S., Berntsen, P., Bogan, M., Van Driel, T. B. & 26 others, Doak, R. B., Kjær, K. S., Frank, M., Fromme, R., Grotjohann, I., Henning, R., Hunter, M. S., Kirian, R., Kosheleva, I., Kupitz, C., Liang, M., Martin, A. V., Nielsen, M. M., Messerschmidt, M., Seibert, M. M., Sjöhamn, J., Stellato, F., Weierstall, U., Zatsepin, N., Spence, J., Fromme, P., Schlichting, I., Boutet, S., Groenhof, G., Chapman, H. N. & Neutze, R., 2014, In : Nature Methods. 11, 9, p. 923-926 4 p.

Research output: Contribution to journalArticle

Free electron lasers
X ray scattering
Lasers
X-Rays
Electrons
8 Citations (Scopus)

X-ray crystal structure of the passenger domain of plasmid encoded toxin(Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC)

Domingo Meza-Aguilar, J., Fromme, P., Torres-Larios, A., Mendoza-Hernández, G., Hernandez-Chiñas, U., Arreguin-Espinosa De Los Monteros, R. A., Eslava Campos, C. A. & Fromme, R., Mar 7 2014, In : Biochemical and Biophysical Research Communications. 445, 2, p. 439-444 6 p.

Research output: Contribution to journalArticle

Enterotoxins
Escherichia coli
Plasmids
Crystal structure
X-Rays
2015
66 Citations (Scopus)

A novel inert crystal delivery medium for serial femtosecond crystallography

Conrad, C. E., Basu, S., James, D., Wang, D., Schaffer, A., Roy-Chowdhury, S., Zatsepin, N., Aquila, A., Coe, J., Gati, C., Hunter, M. S., Koglin, J. E., Kupitz, C., Nelson, G., Subramanian, G., White, T. A., Zhao, Y., Zook, J., Boutet, S., Cherezov, V. & 4 others, Spence, J., Fromme, R., Weierstall, U. & Fromme, P., Jul 1 2015, In : IUCrJ. 2, p. 421-430 10 p.

Research output: Contribution to journalArticle

Crystallography
crystallography
delivery
Sepharose
proteins
2 Citations (Scopus)

Biophysical characterization of a vaccine candidate against HIV-1: The transmembrane and membrane proximal domains of HIV-1 gp41 as a maltose binding protein fusion

Gong, Z., Martin-Garcia, J. M., Daskalova, S. M., Craciunescu, F. M., Song, L., Dörner, K., Hansen, D., Yang, J. H., LaBaer, J., Hogue, B., Leket-Mor, T. & Fromme, P., Aug 21 2015, In : PLoS One. 10, 8, e0136507.

Research output: Contribution to journalArticle

Maltose-Binding Proteins
maltose
Human immunodeficiency virus 1
HIV-1
binding proteins
4 Citations (Scopus)

Biphasic droplet-based sample delivery of protein crystals for serial femtosecond crystallography with an x-ray free electron laser

Echelmeier, A., Nelson, G., Abdallah, B. G., James, D., Roy-Chowdhury, S., Tolstikova, A., Mariani, V., Kirian, R., Oberthüer, D., Dörner, K., Fromme, P., Chapman, H. N., Weierstall, U., Spence, J. & Ros, A., 2015, MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 1374-1376 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Crystallography
Free electron lasers
X ray lasers
Proteins
X rays
8 Citations (Scopus)

Critical assessment of the emission spectra of various photosystem II core complexes

Chen, J., Kell, A., Acharya, K., Kupitz, C., Fromme, P. & Jankowiak, R., Apr 2 2015, In : Photosynthesis Research. 124, 3, p. 253-265 13 p.

Research output: Contribution to journalArticle

Photosystem II Protein Complex
photosystem II
Spinacia oleracea
spinach
Electron energy levels
5 Citations (Scopus)

Crystallization of photosystem II for time-resolved structural studies using an X-ray free electron laser

Coe, J., Kupitz, C., Basu, S., Conrad, C. E., Roy-Chowdhury, S., Fromme, R. & Fromme, P., 2015, In : Methods in Enzymology. 557, p. 459-482 24 p.

Research output: Contribution to journalArticle

X ray lasers
Photosystem II Protein Complex
Free electron lasers
Crystallization
Lasers
371 Citations (Scopus)

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Kang, Y., Zhou, X. E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T. A., Yefanov, O., Han, G. W., Xu, Q., De Waal, P. W., Ke, J., Tan, M. H. E., Zhang, C., Moeller, A., West, G. M., Pascal, B. D., Van Eps, N., Caro, L. N. & 52 others, Vishnivetskiy, S. A., Lee, R. J., Suino-Powell, K. M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G. J., Messerschmidt, M., Gati, C., Zatsepin, N., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C. E., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C. S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H. N., Spence, J., Fromme, P., Weierstall, U., Ernst, O. P., Katritch, V., Gurevich, V. V., Griffin, P. R., Hubbell, W. L., Stevens, R. C., Cherezov, V., Melcher, K. & Xu, H. E., Jul 30 2015, In : Nature. 523, 7562, p. 561-567 7 p.

Research output: Contribution to journalArticle

Arrestin
Rhodopsin
Lasers
X-Rays
G-Protein-Coupled Receptors
13 Citations (Scopus)

High throughput protein nanocrystal fractionation in a microfluidic sorter

Abdallah, B. G., Roy-Chowdhury, S., Coe, J., Fromme, P. & Ros, A., Apr 21 2015, In : Analytical Chemistry. 87, 8, p. 4159-4167 9 p.

Research output: Contribution to journalArticle

Fractionation
Sorting
Microfluidics
Nanocrystals
Throughput
10 Citations (Scopus)

Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction

Abdallah, B. G., Zatsepin, N., Roy-Chowdhury, S., Coe, J., Conrad, C. E., Dörner, K., Sierra, R. G., Stevenson, H. P., Camacho-Alanis, F., Grant, T. D., Nelson, G., James, D., Calero, G., Wachter, R., Spence, J., Weierstall, U., Fromme, P. & Ros, A., Jul 1 2015, In : Structural Dynamics. 2, 4, 041719.

Research output: Contribution to journalArticle

X ray lasers
Free electron lasers
classifying
Sorting
Microfluidics
3 Citations (Scopus)

NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins

Zook, J., Mo, G., Sisco, N. J., Craciunescu, F. M., Hansen, D., Baravati, B., Cherry, B., Sykes, K., Wachter, R., Van Horn, W. & Fromme, P., Jun 3 2015, In : Structure. 23, 6, p. 1116-1122 7 p., 3165.

Research output: Contribution to journalArticle

Francisella tularensis
Allergens
Lipoproteins
Virulence
Magnetic Resonance Spectroscopy
66 Citations (Scopus)
Crystallography
Crystals
Membrane Proteins
Proteins
Crystallization
2 Citations (Scopus)

Purification and biochemical characterization of the ATP synthase from Heliobacterium modesticaldum

Yang, J. H., Sarrou, I., Martin-Garcia, J. M., Zhang, S., Redding, K. & Fromme, P., Jun 8 2015, In : Protein Expression and Purification. 114, p. 1-8 8 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Detergents
Adenosine Triphosphatases
Gels
Holoenzymes
34 Citations (Scopus)

Serial femtosecond crystallography of soluble proteins in lipidic cubic phase

Fromme, R., Ishchenko, A., Metz, M., Chowdhury, S. R., Basu, S., Boutet, S., Fromme, P., White, T. A., Barty, A., Spence, J., Weierstall, U., Liu, W. & Cherezov, V., Sep 1 2015, In : IUCrJ. 2, p. 545-551 7 p.

Research output: Contribution to journalArticle

Crystallography
crystallography
Microcrystals
proteins
Proteins
9 Citations (Scopus)

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Lawrence, R. M., Conrad, C. E., Zatsepin, N., Grant, T. D., Liu, H., James, D., Nelson, G., Subramanian, G., Aquila, A., Hunter, M. S., Liang, M., Boutet, S., Coe, J., Spence, J., Weierstall, U., Liu, W., Fromme, P., Cherezov, V. & Hogue, B., Jul 1 2015, In : Structural Dynamics. 2, 4, 041720.

Research output: Contribution to journalArticle

Microcrystals
microcrystals
viruses
Viruses
X ray diffraction
94 Citations (Scopus)

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

Fenalti, G., Zatsepin, N., Betti, C., Giguere, P., Han, G. W., Ishchenko, A., Liu, W., Guillemyn, K., Zhang, H., James, D., Wang, D., Weierstall, U., Spence, J., Boutet, S., Messerschmidt, M., Williams, G. J., Gati, C., Yefanov, O. M., White, T. A., Oberthuer, D. & 16 others, Metz, M., Yoon, C. H., Barty, A., Chapman, H. N., Basu, S., Coe, J., Conrad, C. E., Fromme, R., Fromme, P., Tourwé, D., Schiller, P. W., Roth, B. L., Ballet, S., Katritch, V., Stevens, R. C. & Cherezov, V., Mar 6 2015, In : Nature Structural and Molecular Biology. 22, 3, p. 265-268 4 p.

Research output: Contribution to journalArticle

Opioid Receptors
Peptides
Analgesics
Opiate Alkaloids
phenylalanylphenylalanine
20 Citations (Scopus)

Ternary structure reveals mechanism of a membrane diacylglycerol kinase

Li, D., Stansfeld, P. J., Sansom, M. S. P., Keogh, A., Vogeley, L., Howe, N., Lyons, J. A., Aragao, D., Fromme, P., Fromme, R., Basu, S., Grotjohann, I., Kupitz, C., Rendek, K., Weierstall, U., Zatsepin, N., Cherezov, V., Liu, W., Bandaru, S., English, N. J. & 10 others, Gati, C., Barty, A., Yefanov, O., Chapman, H. N., Diederichs, K., Messerschmidt, M., Boutet, S., Williams, G. J., Seibert, M. M. & Caffrey, M., Dec 17 2015, In : Nature Communications. 6, 10140.

Research output: Contribution to journalArticle

Diacylglycerol Kinase
adenosine triphosphate
Adenosine Triphosphate
membranes
Membranes
15 Citations (Scopus)

XFELs open a new era in structural chemical biology

Fromme, P., Dec 1 2015, In : Nature Chemical Biology. 11, 12, p. 895-899 5 p.

Research output: Contribution to journalArticle

Molecular Models
Molecular Structure
Lasers
X-Rays
Proteins