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1986 …2024
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Research Output 1986 2019

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Article
1986
1 Citation (Scopus)

Computer simulated metabolism: A student-interactive program

Tirri, L. J. & Jurutka, P., 1986, In : Journal of Chemical Education. 63, 12, p. 1071-1072 2 p.

Research output: Contribution to journalArticle

Metabolism
Students
student
1991
180 Citations (Scopus)

Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function

Hsieh, J. C., Jurutka, P., Galligan, M. A., Terpening, C. M., Haussler, C. A., Samuels, D. S., Shimizu, Y., Shimizu, N. & Haussler, M. R., Oct 15 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9315-9319 5 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Serine
Protein Kinase C
Phosphorylation
Vitamin D
115 Citations (Scopus)

The vitamin D-responsive element in the rat bone gla protein gene is an imperfect direct repeat that cooperates with other cis-elements in 1,25-dihydroxyvitamin D3-mediated transcriptional activation

Terpening, C. M., Haussler, C. A., Jurutka, P., Galligan, M. A., Komm, B. S. & Haussler, M. R., Mar 1991, In : Molecular Endocrinology. 5, 3, p. 373-385 13 p.

Research output: Contribution to journalArticle

Calcitriol
Nucleic Acid Repetitive Sequences
Osteocalcin
Vitamin D
Transcriptional Activation
28 Citations (Scopus)

Vitamin D receptor phosphorylation in transfected ROS 17/2.8 cells is localized to the N-terminal region of the hormone-binding domain

Jones, B. B., Jurutka, P., Haussler, C. A., Haussler, M. R. & Whitfield, G. K., 1991, In : Molecular Endocrinology. 5, 8, p. 1137-1146 10 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Phosphorylation
Hormones
Casein Kinase II
Calcitriol
1993
85 Citations (Scopus)

Phosphorylation of serine 208 in the human vitamin D receptor: The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells

Jurutka, P., Hsieh, J. C., MacDonald, P. N., Terpening, C. M., Haussier, C. A., Haussler, M. R. & Whitfield, G. K., Mar 25 1993, In : Journal of Biological Chemistry. 268, 9, p. 6791-6799 9 p.

Research output: Contribution to journalArticle

Casein Kinase II
Calcitriol Receptors
Phosphorylation
Serine
Amino Acids
31 Citations (Scopus)
Calcitriol Receptors
Phosphorylation
COS Cells
Cyclic AMP-Dependent Protein Kinases
Calcitriol
101 Citations (Scopus)

Phosphorylation of the human vitamin D receptor by protein kinase C: Biochemical and functional evaluation of the serine 51 recognition site

Hsieh, J. C., Jurutka, P., Nakajima, S., Galligan, M. A., Haussler, C. A., Shimizu, Y., Shimizu, N., Whitfield, G. K. & Haussler, M. R., Jul 15 1993, In : Journal of Biological Chemistry. 268, 20, p. 15118-15126 9 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Phosphorylation
Serine
Protein Kinase C
Vitamin D
18 Citations (Scopus)

Purified Human Vitamin D Receptor Overexpressed in Escherichia coli and Baculovirus Systems Does Not Bind 1,25-Dihydroxyvitamin D3 Hormone Efficiently Unless Supplemented with a Rat Liver Nuclear Extract

Nakajima, S., Hsieh, J. C., Macdonald, P. N., Haussler, C. A., Galligan, M. A., Jurutka, P. & Haussler, M. R., Dec 15 1993, In : Biochemical and Biophysical Research Communications. 197, 2, p. 478-485 8 p.

Research output: Contribution to journalArticle

Liver Extracts
Calcitriol Receptors
Calcitriol
Baculoviridae
Liver
31 Citations (Scopus)
Casein Kinase II
Calcitriol Receptors
Phosphorylation
Osteoblasts
Rats
1995
84 Citations (Scopus)

A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation

Whitfield, G. K., Hsieh, J. C., Nakajima, S., MacDonald, P. N., Thompson, P. D., Jurutka, P., Haussler, C. A. & Haussler, M. R., 1995, In : Molecular Endocrinology. 9, 9, p. 1166-1179 14 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Calcitriol Receptors
Vitamin D
Transcriptional Activation
Hormones
64 Citations (Scopus)

Genomic actions of 1,25-dihydroxyvitamin D3

Whitfield, G. K., Hsieh, J. C., Jurutka, P., Selznick, S. H., Haussler, C. A., MacDonald, P. N. & Haussler, M. R., 1995, In : Journal of Nutrition. 125, 6 SUPPL.

Research output: Contribution to journalArticle

calcitriol
Calcitriol Receptors
Calcitriol
vitamin D
Retinoid X Receptors
94 Citations (Scopus)

New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone

Haussler, M. R., Jurutka, P., Hsieh, J. C., Thompson, P. D., Selznick, S. H., Haussler, C. A. & Whitfield, G. K., 1995, In : Bone. 17, 2 SUPPL. 1

Research output: Contribution to journalArticle

Retinoid X Receptors
Calcitriol Receptors
Vitamin D
Hormones
Transcription Factor TFIIB
18 Citations (Scopus)

Receptor mediated genomic action of the 1,25(OH)2D3 hormone: Expression of the human vitamin D receptor in E. coli

Hsieh, J. C., Nakajima, S., Galligan, M. A., Jurutka, P., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 53, 1-6, p. 583-594 12 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Retinoid X Receptors
Escherichia coli
Hormones
Vitamin D
28 Citations (Scopus)

The T-Box near the Zinc Fingers of the Human Vitamin D Receptor Is Required for Heterodimeric DNA Binding and Transactivation

Hsieh, J. C., Jurutka, P., Selznick, S. H., Reeder, M. C., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Oct 4 1995, In : Biochemical and Biophysical Research Communications. 215, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Zinc Fingers
Transcriptional Activation
Retinoid X Receptors
Zinc
178 Citations (Scopus)

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription

Blanco, J. C. G., Wang, I. M., Tsai, S. Y., Tsai, M. J., O'Malley, B. W., Jurutka, P., Haussler, M. R. & Ozato, K., Feb 28 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 5, p. 1535-1539 5 p.

Research output: Contribution to journalArticle

Transcription Factor TFIIB
Calcitriol Receptors
Cytoplasmic and Nuclear Receptors
Ligands
Transfection
1996
65 Citations (Scopus)
CCAAT-Binding Factor
Vitamin D Response Element
Retinoid X Receptors
Dilatation and Curettage
Calcitriol Receptors
26 Citations (Scopus)

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor

Nakajima, S., Hsieh, J. C., Jurutka, P., Galligan, M. A., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Mar 1 1996, In : Journal of Biological Chemistry. 271, 9, p. 5143-5149 7 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Cysteine
Hormones
Ligands
Vitamin D
76 Citations (Scopus)

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation

Jurutka, P., Hsieh, J. C., Nakajima, S., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Apr 16 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 8, p. 3519-3524 6 p.

Research output: Contribution to journalArticle

Casein Kinase II
Calcitriol Receptors
Transcriptional Activation
Phosphorylation
Vitamin D
21 Citations (Scopus)

Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR

Blanco, J. C. G., Dey, A., Leid, M., Minucci, S., Park, B. K., Jurutka, P., Haussler, M. R. & Ozato, K., 1996, In : Genes to Cells. 1, 2, p. 209-221 13 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Ligands
Retinoic Acid Receptors
Clone Cells
Embryonal Carcinoma Stem Cells
103 Citations (Scopus)

Vitamin D receptors from patients with resistance to 1,25- dihydroxyvitamin D3: Point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner

Whitfield, G. K., Selznick, S. H., Haussler, C. A., Hsieh, J. C., Galligan, M. A., Jurutka, P., Thompson, P. D., Lee, S. M., Zerwekh, J. E. & Haussler, M. R., 1996, In : Molecular Endocrinology. 10, 12, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Calcitriol Receptors
Calcitriol
Point Mutation
Transcriptional Activation
1997
74 Citations (Scopus)

Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C- terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription factor IIB, in vitro

Jurutka, P., Hsieh, J. C., Remus, L. S., Whitfield, G. K., Thompson, P. D., Haussler, C. A., Blanco, J. C. G., Ozato, K. & Haussler, M. R., Jun 6 1997, In : Journal of Biological Chemistry. 272, 23, p. 14592-14599 8 p.

Research output: Contribution to journalArticle

Transcription Factor TFIIB
Calcitriol Receptors
Furylfuramide
Transcriptional Activation
Chemical activation
241 Citations (Scopus)

The vitamin D hormone and its nuclear receptor: Molecular actions and disease states

Haussler, M. R., Haussler, C. A., Jurutka, P., Thompson, P. D., Hsieh, J. C., Remus, L. S., Selznick, S. H. & Whitfield, G. K., Sep 1997, In : Journal of Endocrinology. 154, SUPPL.

Research output: Contribution to journalArticle

Calcitriol Receptors
Cytoplasmic and Nuclear Receptors
Retinoid X Receptors
Vitamin D
Furylfuramide
1998
93 Citations (Scopus)

Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis- retinoic acid. Evidence for allosteric receptor interactions

Thompson, P. D., Jurutka, P., Haussler, C. A., Whitfield, G. K. & Haussler, M. R., Apr 3 1998, In : Journal of Biological Chemistry. 273, 14, p. 8483-8491 9 p.

Research output: Contribution to journalArticle

Vitamin D Response Element
Retinoid X Receptors
Calcitriol Receptors
Calcitriol
DNA
53 Citations (Scopus)

Novel nuclear localization signal between the two DNA-binding zinc fingers in the human vitamin D receptor

Hsieh, J. C., Shimizu, Y., Minoshima, S., Shimizu, N., Haussler, C. A., Jurutka, P. & Haussler, M. R., Jul 1 1998, In : Journal of Cellular Biochemistry. 70, 1, p. 94-109 16 p.

Research output: Contribution to journalArticle

Nuclear Localization Signals
Calcitriol Receptors
Zinc Fingers
Zinc
DNA
28 Citations (Scopus)

Suppression of ANP gene transcription by liganded vitamin D receptor: Involvement of specific receptor domains

Chen, S., Wu, J., Hsieh, J. C., Whitfield, G. K., Jurutka, P., Haussler, M. R. & Gardner, D. G., Jun 1998, In : Hypertension. 31, 6, p. 1338-1342 5 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Atrial Natriuretic Factor
Genes
Chloramphenicol O-Acetyltransferase
Retinoid X Receptors
1089 Citations (Scopus)

The nuclear vitamin D receptor: Biological and molecular regulatory properties revealed

Haussler, M. R., Whitfield, G. K., Haussler, C. A., Hsieh, J. C., Thompson, P. D., Selznick, S. H., Dominguez, C. E. & Jurutka, P., 1998, In : Journal of Bone and Mineral Research. 13, 3, p. 325-349 25 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Vitamin D
Prostatic Neoplasms
Homeostasis
Hormones
1999
32 Citations (Scopus)

Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor

Hsieh, J. C., Whitfield, G. K., Oza, A. K., Dang, H. T. L., Price, J. N., Galligan, M. A., Jurutka, P., Thompson, P. D., Haussler, C. A. & Haussler, M. R., Dec 7 1999, In : Biochemistry. 38, 49, p. 16347-16358 12 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Zinc Fingers
Transcriptional Activation
Zinc
Chemical activation
141 Citations (Scopus)

Steroid hormone receptors: Evolution, ligands, and molecular basis of biologic function

Whitfield, G. K., Jurutka, P., Haussler, C. A. & Haussler, M. R., 1999, In : Journal of Cellular Biochemistry. 76, SUPPL. 32/33, p. 110-122 13 p.

Research output: Contribution to journalArticle

Steroid hormones
Molecular Evolution
Steroid Receptors
Cytoplasmic and Nuclear Receptors
Hormones
22 Citations (Scopus)

Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor

Thompson, P. D., Hsieh, J. C., Whitfield, G. K., Haussler, C. A., Jurutka, P., Galligan, M. A., Tillman, J. B., Spindler, S. R. & Haussler, M. R., Dec 1 1999, In : Journal of Cellular Biochemistry. 75, 3, p. 462-480 19 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Thyroid Hormone Receptors
Calcitriol Receptors
Vitamin D Response Element
Transcriptional Activation
2000
7 Citations (Scopus)

Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts

Jurutka, P., Remus, L. S., Whitfield, G. K., Galligan, M. A., Haussler, C. A. & Haussler, M. R., Jan 27 2000, In : Biochemical and Biophysical Research Communications. 267, 3, p. 813-819 7 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Calcitriol Receptors
Osteoblasts
Chemical activation
Transcriptional Activation
290 Citations (Scopus)

The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB

Jurutka, P., Remus, L. S., Whitfield, G. K., Thompson, P. D., Hsieh, J. C., Zitzer, H., Tavakkoli, P., Galligan, M. A., Dang, H. T. L., Haussler, C. A. & Haussler, M. R., 2000, In : Molecular Endocrinology. 14, 3, p. 401-420 20 p.

Research output: Contribution to journalArticle

Transcription Factor TFIIB
Calcitriol Receptors
Protein Isoforms
Alanine
Transcriptional Activation
2001
53 Citations (Scopus)

Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts

Thompson, P. D., Remus, L. S., Hsieh, J. C., Jurutka, P., Whitfield, G. K., Galligan, M. A., Encinas Dominguez, C., Haussler, C. A. & Haussler, M. R., 2001, In : Journal of Molecular Endocrinology. 27, 2, p. 211-227 17 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Calcitriol Receptors
Transcriptional Activation
Aminoacylation
Gene Expression
297 Citations (Scopus)

Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene

Kerr Whitfield, G., Remus, L. S., Jurutka, P., Zitzer, H., Oza, A. K., Dang, H. T. L., Haussler, C. A., Galligan, M. A., Thatcher, M. L., Dominguez, C. E. & Haussler, M. R., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 145-159 15 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Polymorphism
Genes
Genotype
Exons
202 Citations (Scopus)

Molecular Nature of the Vitamin D Receptor and its Role in Regulation of Gene Expression

Jurutka, P., Whitfield, G. K., Hsieh, J. C., Thompson, P. D., Haussler, C. A. & Haussler, M. R., 2001, In : Reviews in Endocrine and Metabolic Disorders. 2, 2, p. 203-216 14 p.

Research output: Contribution to journalArticle

Familial Hypophosphatemic Rickets
Retinoid X Receptors
Calcitriol Receptors
Gene Expression Regulation
Vitamin D
2002
34 Citations (Scopus)

Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor

Jurutka, P., MacDonald, P. N., Nakajima, S., Hsieh, J. C., Thompson, P. D., Kerr Whitfield, G., Galligan, M. A., Haussler, C. A. & Haussler, M. R., 2002, In : Journal of Cellular Biochemistry. 85, 2, p. 435-457 23 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Phosphorylation
Baculoviridae
Retinoid X Receptors
Vitamin D
110 Citations (Scopus)

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements

Thompson, P. D., Jurutka, P., Whitfield, G. K., Myskowski, S. M., Eichhorst, K. R., Encinas Dominguez, C., Haussler, C. A. & Haussler, M. R., 2002, In : Biochemical and Biophysical Research Communications. 299, 5, p. 730-738 9 p.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Cytochrome P-450 CYP3A
Calcitriol Receptors
Vitamin D
Colonic Neoplasms
2 Citations (Scopus)

The nuclear vitamin D receptor: From clinical radioreceptor assay of the vitamin D hormone to genomics, proteomics and a novel ligand

Haussler, M. R., Haussler, C. A., Jurutka, P., Encinas Dominguez, C., Hsieh, J. C., Thatcher, M. L. & Whitfield, G. K., Jun 2002, In : Journal of Clinical Ligand Assay. 25, 2, p. 221-228 8 p.

Research output: Contribution to journalArticle

Radioligand Assay
Calcitriol Receptors
Genomics
Vitamin D
Proteomics
2003
166 Citations (Scopus)

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

Hsieh, J. C., Sisk, J. M., Jurutka, P., Haussler, C. A., Slater, S. A., Haussler, M. R. & Thompson, C. C., Oct 3 2003, In : Journal of Biological Chemistry. 278, 40, p. 38665-38674 10 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Calcitriol Receptors
Hair
Proteins
Cytoplasmic and Nuclear Receptors
15 Citations (Scopus)

Two Basic Amino Acids C-Terminal of the Proximal Box Specify Functional Binding of the Vitamin D Receptor to Its Rat Osteocalcin Deoxyribonucleic Acid-Responsive Element

Hsieh, J. C., Whitfield, G. K., Jurutka, P., Haussler, C. A., Thatcher, M. L., Thompson, P. D., Dang, H. T. L., Galligan, M. A., Oza, A. K. & Haussler, M. R., Nov 2003, In : Endocrinology. 144, 11, p. 5065-5080 16 p.

Research output: Contribution to journalArticle

Basic Amino Acids
Calcitriol Receptors
Osteocalcin
DNA
Glucocorticoid Receptors
2004
30 Citations (Scopus)

1,25-Dihydroxyvitamin D3 down-regulation of PHEX gene expression is mediated by apparent repression of a 110 kDa transfactor that binds to a polyadenine element in the promoter

Hines, E. R., Kolek, O. I., Jones, M. D., Serey, S. H., Sirjani, N. B., Kiela, P. R., Jurutka, P., Haussler, M. R., Collins, J. F. & Ghishan, F. K., Nov 5 2004, In : Journal of Biological Chemistry. 279, 45, p. 46406-46414 9 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Calcitriol
Gene Expression Regulation
Gene expression
Down-Regulation
14 Citations (Scopus)

Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH) 2D 3-dependent transactivation

Hsieh, J. C., Dang, H. T. L., Galligan, M. A., Whitfield, G. K., Haussler, C. A., Jurutka, P. & Haussler, M. R., Nov 12 2004, In : Biochemical and Biophysical Research Communications. 324, 2, p. 801-809 9 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Phosphorylation
Protein-Serine-Threonine Kinases
Protein Kinases
Serine
2005
69 Citations (Scopus)

Molecular and functional comparison of 1,25-dihydroxyvitamin D3 and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4

Jurutka, P., Thompson, P. D., Whitfield, G. K., Eichhorst, K. R., Hall, N., Dominguez, C. E., Hsieh, J. C., Haussler, C. A. & Haussler, M. R., Apr 1 2005, In : Journal of Cellular Biochemistry. 94, 5, p. 917-943 27 p.

Research output: Contribution to journalArticle

Lithocholic Acid
Cytochrome P-450 CYP3A
Calcitriol Receptors
Calcitriol
Transcription
2007
118 Citations (Scopus)

1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism

Barthel, T. K., Mathern, D. R., Whitfield, G. K., Haussler, C. A., Hopper IV, H. A., Hsieh, J. C., Slater, S. A., Hsieh, G., Kaczmarska, M., Jurutka, P., Kolek, O. I., Ghishan, F. K. & Haussler, M. R., Mar 2007, In : Journal of Steroid Biochemistry and Molecular Biology. 103, 3-5, p. 381-388 8 p.

Research output: Contribution to journalArticle

Calcitriol
Metabolism
Minerals
Bone
Genes
100 Citations (Scopus)

Vitamin D receptor: Key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands

Jurutka, P., Bartik, L., Whitfield, G. K., Mathern, D. R., Barthel, T. K., Gurevich, M., Hsieh, J. C., Kaczmarska, M., Haussler, C. A. & Haussler, M. R., Dec 2007, In : Journal of Bone and Mineral Research. 22, SUPPL. 2

Research output: Contribution to journalArticle

Calcitriol Receptors
Minerals
Ligands
Bone and Bones
Retinoid X Receptors
2008
4 Citations (Scopus)

Presence of a TA haplotype in the APC gene containing the common 1822 polymorphism and colorectal adenoma

Egan, J. B., Jacobs, E. T., Martínez, M. E., Gerner, E. W., Jurutka, P. & Thompson, P. A., Jul 15 2008, In : Cancer Research. 68, 14, p. 6006-6013 8 p.

Research output: Contribution to journalArticle

APC Genes
Adenoma
Haplotypes
Codon
Single Nucleotide Polymorphism
199 Citations (Scopus)

Vitamin D receptor: Molecular signaling and actions of nutritional ligands in disease prevention

Haussler, M. R., Haussler, C. A., Bartik, L., Whitfield, G. K., Hsieh, J. C., Slater, S. & Jurutka, P., Oct 2008, In : Nutrition Reviews. 66, SUPPL.2

Research output: Contribution to journalArticle

Calcitriol Receptors
Ligands
Co-Repressor Proteins
Hair
Tocotrienols
2009
44 Citations (Scopus)

Modeling, synthesis and biological evaluation of potential Retinoid X Receptor (RXR) selective agonists: Novel analogues of 4-[1-(3,5,5,8,8- pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene)

Wagner, C., Jurutka, P., Marshall, P., Groy, T. L., Van Der Vaart, A., Ziller, J. W., Furmick, J. K., Graeber, M. E., Matro, E., Miguel, B. V., Tran, I. T., Kwon, J., Tedeschi, J. N., Moosavi, S., Danishyar, A., Philp, J. S., Khamees, R. O., Jackson, J. N., Grupe, D. K., Badshah, S. L. & 1 others, Hart, J. W., Oct 8 2009, In : Journal of Medicinal Chemistry. 52, 19, p. 5950-5966 17 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Benzoic Acid
Apoptosis
Cutaneous T-Cell Lymphoma
Drug Design
10 Citations (Scopus)

Vitamin D, calcium, and colorectal neoplasia: New insights on mechanisms of action

Jacobs, E. T., Jurutka, P., Martínez, M. E. & Alberts, D. S., Mar 2009, In : Cancer Prevention Research. 2, 3, p. 197-199 3 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-bcl-2
bcl-2-Associated X Protein
Biological Models
Vitamin D
Colorectal Neoplasms
2010
24 Citations (Scopus)

Association between polymorphic variation in VDR and RXRA and circulating levels of vitamin D metabolites

Hibler, E. A., Jurutka, P., Egan, J. B., Hu, C., LeRoy, E. C., Martinez, M. E., Thompson, P. A. & Jacobs, E. T., Jul 2010, In : Journal of Steroid Biochemistry and Molecular Biology. 121, 1-2, p. 438-441 4 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Metabolites
Vitamin D
Single Nucleotide Polymorphism
Polymorphism
1 Citation (Scopus)

Conversion of the anti-tumor agent tasidotin (ILX651) to its active metabolite by prolyl oligopeptidase

Deutch, C. E., Krumbholz, R., Schmid, S. M., Bonate, P. L. & Jurutka, P., Mar 5 2010, In : Enzyme and Microbial Technology. 46, 3-4, p. 246-251 6 p.

Research output: Contribution to journalArticle

prolyl oligopeptidase
Metabolites
Metabolism
Peptides
Tumors