Michael Sierks

Arizona Department of Health Services

8/1/22 → 7/31/24

Project: Research project

Arizona Alzheimer's Consortium (AAC) FY23 Match

Ofori, E., Wang, Y., Mastroeni, D., Youngstedt, S., Coon, D., Yeom, D. J., Bimonte-Nelson, H., Sierks, M., Schaefer, S., Stabenfeldt, S., Brafman, D., Klein-Seetharaman, J., Shishegar, N., Readhead, B., Maxfield, M. & Verpeut, J.

7/1/22 → 6/30/23

Project: Research project

A Novel Multiparameter Blood Test for Early Detection of Alzheimer s Disease

1/30/22 → 8/31/24

Project: Research project

Targeting Toxic Oligomeric Protein Variants Generated after Traumatic Brain Injury to Decrease Risk of AD

DOD-ARMY: Army Medical Research Acquisition Activity (USAMRAA)

9/1/21 → 8/31/24

Project: Research project

Protein variants as blood based biomarkers for diagnosing and staging AD

Arizona Department of Health Services

9/1/16 → 6/30/23

Project: Research project

Finished

Arizona Alzheimer's Consortium (AAC) FY22 - Match Projects

Sierks, M., Coon, D., Wilson, M., Mastroeni, D., Krajmalnik-Brown, R., Conrad, C., Stabenfeldt, S., Wang, Y., Schaefer, S., Brafman, D. & Bimonte-Nelson, H.

7/1/21 → 9/30/22

Project: Research project

2018 MCASU Faculty Summer Residency Program: Sierks

Mayo Clinic Arizona

6/13/18 → 7/25/18

Project: Research project

FY18: Arizona Alzheimer's Consortium

Bimonte-Nelson, H., Conrad, C., Sierks, M., Coon, D., Smith, B. & Coleman, P.

7/1/17 → 6/30/18

Project: Research project

Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment

3/7/17 → 10/6/17

Project: Research project

Treatment of Parkinsons Disease with Enhanced Delivery of Antibody Therapy Selectively Targeting Toxic Protein Variants

3/1/17 → 11/30/21

Project: Research project

FY17: Arizona Alzheimer's Consortium

Bimonte-Nelson, H., Conrad, C., Sierks, M., Coon, D., Smith, B. & Coleman, P.

7/1/16 → 6/30/17

Project: Research project

FY16: Arizona Alzheimer's Consortium

Bimonte-Nelson, H., Sierks, M., Coon, D., Smith, B. & Brafman, D.

7/1/15 → 6/30/16

Project: Research project

Detecting and Treating Traumatic Brain Injury Pathology Progression from the Inside-Out

Stabenfeldt, S., Kodibagkar, V., Sierks, M., Rege, K. & Kleim, J.

9/15/14 → 6/30/19

Project: Research project

Oligomeric Protein Variants as Biomarkers for AD and TBI Susceptibility

DOD-ARMY: Army Medical Research Acquisition Activity (USAMRAA)

9/15/14 → 9/14/19

Project: Research project

14-3-3s as Regulators of Prion-like Mode of Alpha-Synuclein Toxicity

HHS-NIH: National Institute of Neurological Disorders and Stroke (NINDS)

8/1/14 → 7/31/17

Project: Research project

FY15: Arizona Alzheimer's Consortium

Sierks, M., Coon, D., Smith, B., Bimonte-Nelson, H., Hecht, S. & Wang, Y.

7/1/14 → 6/30/15

Project: Research project

Nanobodies selective for oligomeric Tau species isolated from AD brain

HHS-NIH: National Institute on Aging (NIA)

9/30/13 → 6/30/16

Project: Research project

FY14: Arizona Alzheimer's Disease Consortium

Sierks, M., Coon, D., Smith, B., Bimonte-Nelson, H. & Hecht, S.

9/16/13 → 6/30/14

Project: Research project

Development of nanobodies that target amyloid- oligomers for individual diagnosis in Alzheimers disease

Mayo Clinic Jacksonville

2/1/13 → 1/31/15

Project: Research project

Affinity Maturation of an Antibody Based Therapeutic Targeting Microglial Activation

ASU: Mayo Seed Grant

1/1/13 → 12/31/13

Project: Research project

Oligomeric Neuronal Protein Aggregates as Biomarkers for Traumatic Brain Injury (TBI) and Alzheimer Disease (AD)

US Department of Defense (DOD)

9/25/12 → 3/24/15

Project: Research project

Developing Diagnostic Nanobodies Against Aggregated TDP-43 Species

8/1/12 → 7/31/15

Project: Research project

FY 13: Arizona Alzheimer's Disease Consortium

Burleson, M., Sierks, M., Coon, D. & Bimonte-Nelson, H.

7/1/12 → 6/30/13

Project: Research project

Intracellular Tools to Study Specific Misfolded Protein Variants in Human Disease

8/1/11 → 7/31/14

Project: Research project

Intracellular Targeting and Clearance of Toxic Synuclein Aggregates

7/1/11 → 12/31/13

Project: Research project

Arizona Alzheimer's Disease Core Center

Burleson, M., Sierks, M. & Coon, D.

7/1/11 → 6/30/12

Project: Research project

CS: Arizona Alzheimer's Disease Core Center

Burleson, M., Sierks, M. & Coon, D.

7/1/11 → 6/30/12

Project: Research project

Identifying and localizing toxic oligomeric a-syn with morphology specific nanobodies

11/1/10 → 2/28/12

Project: Research project

Morphology specific anti-synuclein nanobodies as therapeutics for PD

11/1/10 → 5/16/13

Project: Research project

High Throughput Tau Oligomer Assay for Drug Screening for Alzheimer's Disease

8/1/10 → 7/31/12

Project: Research project

YR1: Intracellular Targeting and Clearance of Toxic Synuclein Aggregates

7/1/10 → 6/30/12

Project: Research project

In vivo SPECT Imaging of synuclein aggregation with morphology specific antibody based ligands

5/1/10 → 8/23/11

Project: Research project

AZ ASU Alzheimer's Research Center Project - 12

Renaut, R., Marchant, G., Sierks, M., Coon, D. & Bimonte-Nelson, H.

7/1/09 → 6/30/10

Project: Research project

Targeted Hydrolysis of B-amyloid with Engineered Antibody Fragments

Institute for the Study of Aging

1/1/09 → 12/31/09

Project: Research project

In vivo SPECT Imaging of synuclein aggregation with morphology specific antibody based ligands

1/1/09 → 3/31/10

Project: Research project

AZ ASU Alzheimer's Reserach Center Project- Year 11

Renaut, R., Marchant, G., Sierks, M., Coon, D., Johnston, S. & Bimonte-Nelson, H.

7/1/08 → 6/30/09

Project: Research project

High Throughput Tau Oligomer Assay for Drug Screening for Alzheimer's Disease

6/16/08 → 5/1/09

Project: Research project

Conformation-specific Single-chain Antibodies as Neurodegeneration Research Tools

4/1/08 → 3/31/11

Project: Research project

Intrabody Targeting of Toxic Huntington Aggregates

Cure Huntington's Disease Initiative

2/1/08 → 1/31/09

Project: Research project

AZ ASU Alzheimer's Research Center Project - Year 10

Renaut, R., Sierks, M., Coon, D., Johnston, S. & Bimonte-Nelson, H.

7/1/07 → 6/30/08

Project: Research project

Morphology Specific Antibodies to Beta-Amyloid

BrightFocus Foundation

4/1/07 → 3/31/09

Project: Research project

BiaCore Instrument Purchase

Jacobs, B., Sierks, M., Mor, T. & Mason, H.

3/1/07 → 2/28/09

Project: Research project

Intracellular Targeting of Oligomeric a-Synuclein as a Potential Therapeutic for Parkinson's Disease

11/1/06 → 10/31/07

Project: Research project

Morphology Specific Antibodies for Treating Parkinson's - Year 3

OTHER: Arizona Public University (ABOR)

7/1/06 → 6/30/07

Project: Research project

AZ ASU Alzheimer's Research Center Project

Renaut, R., Sierks, M., Coon, D., Johnston, S. & Bimonte-Nelson, H.

7/1/06 → 6/30/07

Project: Research project

Development of a Modular, Fiber Optic Surface Plasmon Resonance Sensor for Quantitation of Diagnostic Proteins for Healing of Burns and Wounds

National Space Biomedical Research Institute

1/1/06 → 1/31/07

Project: Research project

Single Chain Antibody Binding Variable Domains (scFv) Development to Various Morphologies of Htt Aggregation

Cure Huntington's Disease Initiative

10/1/05 → 12/31/06

Project: Research project

Translational Research on Abeta Metabolism, From Synthesis to Clearance

Sun Health Research Institute

9/1/05 → 8/31/08

Project: Research project

Morphology Specific Antibodies for Treating Parkinson's - Year 2

7/1/05 → 6/30/06

Project: Research project

Development of an Early Diagnostic and Treatment for Alzheimer's Disease