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Research Output 1985 2019

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Article
2009
44 Citations (Scopus)

Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays

Wong, J., Sibani, S., Lokko, N. N., LaBaer, J. & Anderson, K., Oct 31 2009, In : Journal of Immunological Methods. 350, 1-2, p. 171-182 12 p.

Research output: Contribution to journalArticle

Enzyme-Linked Immunosorbent Assay
Antigens
Antibodies
Neoplasm Antigens
Serum
68 Citations (Scopus)

The protein structure initiative structural genomics knowledgebase

Berman, H. M., Westbrook, J. D., Gabanyi, M. J., Tao, W., Shah, R., Kouranov, A., Schwede, T., Arnold, K., Kiefer, F., Bordoli, L., Kopp, J., Podvinec, M., Adams, P. D., Carter, L. G., Minor, W., Nair, R. & LaBaer, J., 2009, In : Nucleic Acids Research. 37, SUPPL. 1

Research output: Contribution to journalArticle

Knowledge Bases
Genomics
Research
Proteins
Biota
14 Citations (Scopus)

Vibrio cholerae proteome-wide screen for immunostimulatory proteins identifies phosphatidylserine decarboxylase as a novel toll-like receptor 4 agonist

Thanawastien, A., Montor, W. R., LaBaer, J., Mekalanos, J. J. & Yoon, S. S., Aug 2009, In : PLoS Pathogens. 5, 8, e1000556.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Vibrio cholerae
Proteome
Proteins
Interleukin-6
2008
20 Citations (Scopus)

A biomedically enriched collection of 7000 human ORF clones

Rolfs, A., Hu, Y., Ebert, L., Hoffmann, D., Zuo, D., Ramachandran, N., Raphael, J., Kelley, F., McCarron, S., Jepson, D. A., Shen, B., Baqui, M. M. A., Pearlberg, J., Taycher, E., DeLoughery, C., Hoerlein, A., Korn, B. & LaBaer, J., Jan 30 2008, In : PLoS One. 3, 1, e1528.

Research output: Contribution to journalArticle

Open Reading Frames
open reading frames
Clone Cells
Genes
clones
43 Citations (Scopus)

A functional genomic yeast screen to identify pathogenic bacterial proteins.

Slagowski, N. L., Kramer, R. W., Morrison, M. F., LaBaer, J. & Lesser, C. F., Jan 18 2008, In : PLoS Pathogens. 4, 1

Research output: Contribution to journalArticle

Bacterial Proteins
Yeasts
Proteins
Shigella
Growth
121 Citations (Scopus)

Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer

Anderson, K., Ramachandran, N., Wong, J., Raphael, J. V., Hainsworth, E., Demirkan, G., Cramer, D., Aronzon, D., Hodi, F. S., Harris, L., Logvinenko, T. & LaBaer, J., Apr 2008, In : Journal of Proteome Research. 7, 4, p. 1490-1499 10 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Neoplasm Antigens
Microarrays
Autoantibodies
Breast Neoplasms
58 Citations (Scopus)

Applications of protein microarrays for biomarker discovery

Ramachandran, N., Srivastava, S. & LaBaer, J., 2008, In : Proteomics - Clinical Applications. 2, 10-11, p. 1444-1459 16 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Biomarkers
Microarrays
Proteins
Proteomics
13 Citations (Scopus)
Silanes
Protein Array Analysis
Nucleic Acids
Glass
Coatings
10 Citations (Scopus)
Protein Array Analysis
Nucleic Acids
Proteins
1 Citation (Scopus)
Protein Array Analysis
Nucleic Acids
Plasmids
DNA
Proteins
9 Citations (Scopus)
Biotinylation
Protein Array Analysis
Nucleic Acids
DNA
Proteins
Protein Array Analysis
Nucleic Acids
Proteins
11 Citations (Scopus)
Protein Array Analysis
Nucleic Acids
Proteins
9 Citations (Scopus)
Protein Array Analysis
Nucleic Acids
DNA
Proteins
Cloning
Open Reading Frames
Organism Cloning
Throughput
18 Citations (Scopus)

Lycotoxin-1 insecticidal peptide optimized by amino acid scanning mutagenesis and expressed as a coproduct in an ethanologenic Saccharomyces cerevisiae strain

Hughes, S. R., Dowd, P. F., Hector, R. E., Panavas, T., Sterner, D. E., Qureshi, N., Bischoff, K. M., Bang, S. S., Mertens, J. A., Johnson, E. T., Li, X. L., Jackson, J. S., Caughey, R. J., Riedmuller, S. B., Bartolett, S., Liu, S., Rich, J. O., Farrelly, P. J., Butt, T. R., LaBaer, J. & 1 others, Cotta, M. A., Sep 2008, In : Journal of Peptide Science. 14, 9, p. 1039-1050 12 p.

Research output: Contribution to journalArticle

Mutagenesis
Yeast
Saccharomyces cerevisiae
Yeasts
Insects
18 Citations (Scopus)

Nanotubes light up protein arrays

Srivastava, S. & LaBaer, J., Nov 2008, In : Nature Biotechnology. 26, 11, p. 1244-1246 3 p.

Research output: Contribution to journalArticle

Carbon Nanotubes
Surface plasmon resonance
Antigen-Antibody Complex
Nanotechnology
Nanotubes
228 Citations (Scopus)

Next-generation high-density self-assembling functional protein arrays

Ramachandran, N., Raphael, J. V., Hainsworth, E., Demirkan, G., Fuentes, M. G., Rolfs, A., Hu, Y. & LaBaer, J., Jun 2008, In : Nature Methods. 5, 6, p. 535-538 4 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Complementary DNA
Proteins
Nucleic Acids
Microarrays
28 Citations (Scopus)

Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae

Rolfs, A., Montor, W. R., Sang, S. Y., Hu, Y., Bhullar, B., Kelley, F., McCarron, S., Jepson, D. A., Shen, B., Taycher, E., Mohr, S. E., Zuo, D., Williamson, J., Mekalanos, J. & LaBaer, J., Mar 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 11, p. 4364-4369 6 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Open Reading Frames
Bacteria
Clone Cells
Cholera
35 Citations (Scopus)

Tracking humoral responses using self assembling protein microarrays

Ramachandran, N., Anderson, K., Raphael, J. V., Hainsworth, E., Sibani, S., Montor, W. R., Pacek, M., Wong, J., Eljanne, M., Sanda, M. G., Hu, Y., Logvinenko, T. & LaBaer, J., 2008, In : Proteomics - Clinical Applications. 2, 10-11, p. 1518-1527 10 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Microarrays
Antigens
Humoral Immunity
Autoantigens
3 Citations (Scopus)
Protein Array Analysis
Nucleic Acids
Guidelines
Proteins
3 Citations (Scopus)
Protein Array Analysis
Nucleic Acids
Proteins
Protein Array Analysis
Nucleic Acids
Proteins
2007
18 Citations (Scopus)

A full-genomic sequence-verified protein-coding gene collection for Francisella tularensis

Murthy, T., Rolfs, A., Hu, Y., Shi, Z., Raphael, J., Moreira, D., Kelley, F., McCarron, S., Jepson, D., Taycher, E., Zuo, D., Mohr, S. E., Fernandez, M., Brizuela, L. & LaBaer, J., Jun 27 2007, In : PLoS One. 2, 6, e577.

Research output: Contribution to journalArticle

Francisella tularensis
amino acid sequences
Clone Cells
Genes
clones
7 Citations (Scopus)

A novel approach to sequence validating protein expression clones with automated decision making

Taycher, E., Rolfs, A., Hu, Y., Zuo, D., Mohr, S. E., Williamson, J. & LaBaer, J., Jun 13 2007, In : BMC Bioinformatics. 8, 198.

Research output: Contribution to journalArticle

Protein Sequence
Clone
Decision Making
Clone Cells
Decision making
70 Citations (Scopus)

Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae

Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V. S., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L. & 4 others, Harlow, E., Marsischky, G., Kolodner, R. D. & LaBaer, J., Apr 2007, In : Genome Research. 17, 4, p. 536-543 8 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Clone Cells
Open Reading Frames
Proteins
Yeasts
27 Citations (Scopus)

A systematic approach for testing expression of human full-length proteins in cell-free expression systems

Langlais, C., Guilleaume, B., Wermke, N., Scheuermann, T., Ebert, L., LaBaer, J. & Korn, B., Oct 3 2007, In : BMC Biotechnology. 7, 64.

Research output: Contribution to journalArticle

Cell-Free System
Proteins
Solubility
Escherichia coli
Triticum
54 Citations (Scopus)

c-IAP1 Cooperates with Myc by Acting as a Ubiquitin Ligase for Mad1

Xu, L., Zhu, J., Hu, X., Zhu, H., Kim, H. T., LaBaer, J., Goldberg, A. & Yuan, J., Dec 14 2007, In : Molecular Cell. 28, 5, p. 914-922 9 p.

Research output: Contribution to journalArticle

Dimerization
Ligases
Ubiquitin
Inhibitor of Apoptosis Proteins
Caspase Inhibitors
25 Citations (Scopus)

PlasmID: A centralized repository for plasmid clone information and distribution

Zuo, D., Mohr, S. E., Hu, Y., Taycher, E., Rolfs, A., Kramer, J., Williamson, J. & LaBaer, J., Jan 2007, In : Nucleic Acids Research. 35, SUPPL. 1

Research output: Contribution to journalArticle

Information Dissemination
Plasmids
Clone Cells
Names
Complementary DNA
2006
60 Citations (Scopus)

A reagent resource to identify proteins and peptides of interest for the cancer community

Haab, B. B., Paulovich, A. G., Leigh Anderson, N., Clark, A. M., Downing, G. J., Hermajakob, H., LaBaer, J. & Uhlen, M., Oct 2006, In : Molecular and Cellular Proteomics. 5, 10, p. 1996-2007 12 p.

Research output: Contribution to journalArticle

Proteomics
Peptides
National Cancer Institute (U.S.)
Research
Neoplasms
52 Citations (Scopus)

Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer

Witt, A. E., Hines, L. M., Collins, N. L., Hu, Y., Gunawardane, R. N., Moreira, D., Raphael, J., Jepson, D., Koundinya, M., Rolfs, A., Taron, B., Isakoff, S. J., Brugge, J. S. & LaBaer, J., Mar 2006, In : Journal of Proteome Research. 5, 3, p. 599-610 12 p.

Research output: Contribution to journalArticle

Bioactivity
Proteomics
Complementary DNA
Breast Neoplasms
Genes
77 Citations (Scopus)

Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway

Butcher, R. A., Bhullar, B. S., Perlstein, E. O., Marsischky, G., LaBaer, J. & Schreiber, S. L., Feb 2006, In : Nature Chemical Biology. 2, 2, p. 103-109 7 p.

Research output: Contribution to journalArticle

Sirolimus
Yeasts
6-anilino-5,8-quinolinedione
Growth
TOR Serine-Threonine Kinases
29 Citations (Scopus)

On-chip protein synthesis for making microarrays.

Ramachandran, N., Hainsworth, E., Demirkan, G. & LaBaer, J., 2006, In : Methods in molecular biology (Clifton, N.J.). 328, p. 1-14 14 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Proteins
Nucleic Acids
Printing
Protein Stability
3 Citations (Scopus)

Protein technologies

Chatterjee, D. K. & LaBaer, J., Aug 2006, In : Current Opinion in Biotechnology. 17, 4, p. 334-336 3 p.

Research output: Contribution to journalArticle

Technology
Proteins
8 Citations (Scopus)

Recombinational cloning.

Park, J. & LaBaer, J., May 2006, In : Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]. Chapter 3

Research output: Contribution to journalArticle

Organism Cloning
Proteomics
Genetic Recombination
Proteins
Plasmids
852 Citations (Scopus)

α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

Cooper, A. A., Gitler, A. D., Cashikar, A., Haynes, C. M., Hill, K. J., Bhullar, B., Liu, K., Xu, K., Strathearn, K. E., Liu, F., Cao, S., Caldwell, K. A., Caldwell, G. A., Marsischky, G., Kolodner, R. D., LaBaer, J., Rochet, J. C., Bonini, N. M. & Lindquist, S., Jul 21 2006, In : Science. 313, 5785, p. 324-328 5 p.

Research output: Contribution to journalArticle

Synucleins
Endoplasmic Reticulum
Neurons
Parkinson Disease
Yeasts
2005
3 Citations (Scopus)

A central repository for published plasmids [3]

Fan, M., Tsai, J., Chen, B., Fan, K. & LaBaer, J., Mar 25 2005, In : Science. 307, 5717, p. 1877 1 p.

Research output: Contribution to journalArticle

Biological Specimen Banks
Factual Databases
Genetic Vectors
Plasmids
36 Citations (Scopus)

Building a human kinase gene repository: Bioinformatics, molecular cloning, and functional validation

Park, J., Hu, Y., Murthy, T. V. S., Vannberg, F., Shen, B., Rolfs, A., Hutti, J. E., Cantley, L. C., LaBaer, J., Harlow, E. & Brizuela, L., Jun 7 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 23, p. 8114-8119 6 p.

Research output: Contribution to journalArticle

Molecular Cloning
Computational Biology
Phosphotransferases
Genes
Protein Kinases
2 Citations (Scopus)
Polymorphism
CDNA
Clone
Discrepancy
DNA
132 Citations (Scopus)

Emerging tools for real-time label-free detection of interactions on functional protein microarrays

Ramachandran, N., Larson, D. N., Stark, P. R. H., Hainsworth, E. & LaBaer, J., Nov 2005, In : FEBS Journal. 272, 21, p. 5412-5425 14 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Microarrays
Labels
Technology
Proteins
83 Citations (Scopus)

G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

Collins, N. L., Reginato, M. J., Paulus, J. K., Sgroi, D. C., LaBaer, J. & Brugge, J. S., Jun 2005, In : Molecular and Cellular Biology. 25, 12, p. 5282-5291 10 p.

Research output: Contribution to journalArticle

Anoikis
G1 Phase Cell Cycle Checkpoints
Epidermal Growth Factor
Extracellular Matrix
Cell Survival
1 Citation (Scopus)

Health for life. Genomic medicine: the science speeds up.

Komaroff, A. L. & LaBaer, J., 2005, In : Newsweek. 146, 24, p. 57 1 p.

Research output: Contribution to journalArticle

Human Genome Project
Genetic Research
Medical Genetics
Genomics
Medicine
214 Citations (Scopus)

Protein microarrays as tools for functional proteomics

LaBaer, J. & Ramachandran, N., Feb 2005, In : Current Opinion in Chemical Biology. 9, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Microarrays
Proteomics
Proteins
Protein Interaction Maps
22 Citations (Scopus)

Screens using RNAi and cDNA expression as surrogates for genetics in mammalian tissue culture cells

Pearlberg, J., Degot, S., Endege, W., Park, J., Davies, J., Gelfand, E., Sawyer, J., Conery, A., Doench, J., Li, W., Gonzalez, L., Boyce, F. M., Brizuela, L., LaBaer, J., Grueneberg, D. & Harlow, E., 2005, In : Cold Spring Harbor Symposia on Quantitative Biology. 70, p. 449-459 11 p.

Research output: Contribution to journalArticle

Tissue culture
RNA Interference
tissue culture
Complementary DNA
Cell Culture Techniques
63 Citations (Scopus)

So, you want to look for biomarkers (Introduction to the special biomarkers issue)

LaBaer, J., Jul 2005, In : Journal of Proteome Research. 4, 4, p. 1053-1059 7 p.

Research output: Contribution to journalArticle

Biomarkers
Proteomics
Proteome
Biometrics
Research
2 Citations (Scopus)

The marriage of proteomics and biomarkers

LaBaer, J. & Carr, S. A., Jul 2005, In : Journal of Proteome Research. 4, 4, p. 1043 1 p.

Research output: Contribution to journalArticle

Biomarkers
Marriage
Proteomics
208 Citations (Scopus)

The sentinel within: Exploiting the immune system for cancer biomarkers

Anderson, K. & LaBaer, J., Jul 2005, In : Journal of Proteome Research. 4, 4, p. 1123-1133 11 p.

Research output: Contribution to journalArticle

Immune system
Tumor Biomarkers
Tumors
Immune System
Neoplasm Antigens
2004
35 Citations (Scopus)

Bacterial cell-free system for high-throughput protein expression and a comparative analysis of Escherichia coli cell-free and whole cell expression systems

Murthy, T. V. S., Wu, W., Qiu, Q. Q., Shi, Z., LaBaer, J. & Brizuela, L., Aug 2004, In : Protein Expression and Purification. 36, 2, p. 217-225 9 p.

Research output: Contribution to journalArticle

Cell-Free System
Escherichia coli
Throughput
Proteins
Purification
180 Citations (Scopus)

Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells

Seton-Rogers, S. E., Lu, Y., Hines, L. M., Koundinya, M., LaBaer, J., Muthuswamy, S. K. & Brugge, J. S., Feb 3 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 5, p. 1257-1262 6 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Breast
Extracellular Signal-Regulated MAP Kinases
Epithelial Cells
Epidermal Growth Factor Receptor
2 Citations (Scopus)

From genome to proteome--aim of human proteomics

Nakamura, K., Aebersold, R., Bairoch, A., Dunn, M., Celis, J., Hanash, S., Hochstrasser, D., Humphrey-Smith, I., James, P., Klose, J., LaBaer, J., Langen, H., Mann, M., Parekh, R., Patterson, S., Pearce, C., Poepstorff, P., Simpson, R. J., Tomlinson, I., Tsugita, A. & 1 others, Yates, J., Oct 2004, In : Seikagaku. The Journal of Japanese Biochemical Society. 76, 10, p. 1271-1274 4 p.

Research output: Contribution to journalArticle

Microchip Analytical Procedures
Protein Interaction Mapping
Human Genome Project
Genetic Databases
Nanotechnology