• 8893 Citations
  • 45 h-Index
1985 …2020

Research output per year

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Research Output

2020

Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs

Nagaratnam, N., Tang, Y., Botha, S., Saul, J., Li, C., Hu, H., Zaare, S., Hunter, M., Lowry, D., Weierstall, U., Zatsepin, N., Spence, J. C. H., Qiu, J., LaBaer, J., Fromme, P. & Martin-Garcia, J. M., Jun 1 2020, In : Acta Crystallographica Section F:Structural Biology Communications. 76, p. 278-289 12 p.

Research output: Contribution to journalArticle

Open Access

The role of tumor-stroma interactions on desmoplasia and tumorigenicity within a microengineered 3D platform

Saini, H., Rahmani Eliato, K., Veldhuizen, J., Zare, A., Allam, M., Silva, C., Kratz, A., Truong, D., Mouneimne, G., LaBaer, J., Ros, R. & Nikkhah, M., Jul 2020, In : Biomaterials. 247, 119975.

Research output: Contribution to journalArticle

1 Scopus citations
2019

A human organotypic microfluidic tumor model permits investigation of the interplay between patient-derived fibroblasts and breast cancer cells

Truong, D. D., Kratz, A., Park, J. G., Barrientos, E. S., Saini, H., Nguyen, T., Pockaj, B., Mouneimne, G., LaBaer, J. & Nikkhah, M., Jun 15 2019, In : Cancer Research. 79, 12, p. 3139-3151 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

A noninvasive blood-based combinatorial proteomic biomarker assay to detect breast cancer in women over age 50 with BI-RADS 3, 4, or 5 Assessment

Henderson, M. C., Silver, M., Tran, Q., Letsios, E. E., Mulpuri, R., Reese, D. E., Lourenco, A. P., LaBaer, J., Anderson, K., Alpers, J., Costantini, C., Rohatgi, N., Ali, H., Baker, K., Northfelt, D. W., Ghosh, K., Grobmyer, S. R., Polen, W. & Wolf, J. K., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 142-149 8 p.

Research output: Contribution to journalArticle

Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: Data from the Osteoarthritis Initiative

Camacho-Encina, M., Balboa-Barreiro, V., Rego-Perez, I., Picchi, F., Vanduin, J., Qiu, J., Fuentes, M., Oreiro, N., Labaer, J., Ruiz-Romero, C. & Blanco, F. J., Dec 1 2019, In : Annals of the Rheumatic Diseases. 78, 12, p. 1699-1705 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Kinase inhibitor screening in self-assembled human protein microarrays

Festa, F. & Labaer, J., Oct 2019, In : Journal of Visualized Experiments. 2019, 152, e59886.

Research output: Contribution to journalArticle

Open Access

Multi-platform Approach for Microbial Biomarker Identification Using Borrelia burgdorferi as a Model

Pflughoeft, K. J., Mash, M., Hasenkampf, N. R., Jacobs, M. B., Tardo, A. C., Mitchell Magee, D., Song, L., LaBaer, J., Philipp, M. T., Embers, M. E. & AuCoin, D. P., Jan 1 2019, In : Frontiers in Cellular and Infection Microbiology. 9, JUN, 179.

Research output: Contribution to journalArticle

Open Access
2018

Advances in cell-free protein array methods

Yu, X., Petritis, B., Duan, H., Xu, D. & LaBaer, J., Jan 2 2018, In : Expert Review of Proteomics. 15, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

A Perspective on Proteomics of Infectious Diseases

Venkatesh, A., Gil, C., Fuentes, M., LaBaer, J. & Srivastava, S., Jan 1 2018, (Accepted/In press) In : Proteomics - Clinical Applications.

Research output: Contribution to journalArticle

2 Scopus citations

Expression system for structural and functional studies of human glycosylation enzymes

Moremen, K. W., Ramiah, A., Stuart, M., Steel, J., Meng, L., Forouhar, F., Moniz, H. A., Gahlay, G., Gao, Z., Chapla, D., Wang, S., Yang, J. Y., Prabhakar, P. K., Johnson, R., Rosa, M. D., Geisler, C., Nairn, A. V., Seetharaman, J., Wu, S. C., Tong, L. & 3 others, Gilbert, H. J., LaBaer, J. & Jarvis, D. L., Feb 1 2018, In : Nature Chemical Biology. 14, 2, p. 156-162 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner

Rauf, F., Festa, F., Park, J., Magee, D., Eaton, S., Rinaldi, C., Betanzos, C. M., Gonzalez-Malerva, L. & LaBaer, J., Apr 1 2018, In : Oncogene. 37, 17, p. 2237-2250 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function

Paik, Y. K., Lane, L., Kawamura, T., Chen, Y. J., Cho, J. Y., LaBaer, J., Yoo, J. S., Domont, G., Corrales, F., Omenn, G. S., Archakov, A., Encarnación-Guevara, S., Lui, S., Salekdeh, G. H., Cho, J. Y., Kim, C. Y. & Overall, C. M., Dec 7 2018, In : Journal of Proteome Research. 17, 12, p. 4042-4050 9 p.

Research output: Contribution to journalReview article

15 Scopus citations

Legionella effector AnkX interacts with host nuclear protein PLEKHN1

Yu, X., Noll, R. R., Romero Dueñas, B. P., Allgood, S. C., Barker, K., Caplan, J. L., Machner, M. P., LaBaer, J., Qiu, J. & Neunuebel, M. R., Jan 5 2018, In : BMC Microbiology. 18, 1, 5.

Research output: Contribution to journalArticle

4 Scopus citations

Self-assembling functional programmable protein array for studying protein-protein interactions in malaria parasites

Arévalo-Pinzón, G., González-González, M., Suárez, C. F., Curtidor, H., Carabias-Sánchez, J., Muro, A., LaBaer, J., Patarroyo, M. A. & Fuentes, M., Jul 17 2018, In : Malaria Journal. 17, 1, 270.

Research output: Contribution to journalArticle

4 Scopus citations

Tandem Histone-Binding Domains Enhance the Activity of a Synthetic Chromatin Effector

Tekel, S. J., Vargas, D. A., Song, L., LaBaer, J., Caplan, M. & Haynes, K., Mar 16 2018, In : ACS Synthetic Biology. 7, 3, p. 842-852 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

What's in a sample? Increasing transparency in biospecimen procurement methods

LaBaer, J., Miceli, J. F. & Freedman, L. P., Apr 27 2018, In : Nature Methods. 15, 5, p. 303-304 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
2017

AAgAtlas 1.0: A human autoantigen database

Wang, D., Yang, L., Zhang, P., LaBaer, J., Hermjakob, H., Li, D. & Yu, X., Jan 1 2017, In : Nucleic acids research. 45, D1, p. D769-D776

Research output: Contribution to journalArticle

16 Scopus citations

Autoantibody biomarkers for the detection of serous ovarian cancer

Katchman, B. A., Chowell, D., Wallstrom, G., Vitonis, A. F., LaBaer, J., Cramer, D. W. & Anderson, K., Jul 1 2017, In : Gynecologic Oncology. 146, 1, p. 129-136 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Automatic Identification and Quantification of Extra-Well Fluorescence in Microarray Images

Rivera, R., Wang, J., Yu, X., Demirkan, G., Hopper, M., Bian, X., Tahsin, T., Magee, D., Qiu, J., LaBaer, J. & Wallstrom, G., Nov 3 2017, In : Journal of Proteome Research. 16, 11, p. 3969-3977 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Developing Human Radiation Biodosimetry Models: Testing Cross-Species Conversion Approaches Using an Ex Vivo Model System

Park, J., Paul, S., Briones, N., Zeng, J., Gillis, K., Wallstrom, G., LaBaer, J. & Amundson, S. A., Jun 1 2017, In : Radiation Research. 187, 6, p. 708-721 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Discovering protein-protein interactions using nucleic acid programmable protein arrays

Tang, Y., Qiu, J., Machner, M. & LaBaer, J., Mar 1 2017, In : Current Protocols in Cell Biology. 2017, p. 15.21.1-15.21.14

Research output: Contribution to journalArticle

6 Scopus citations

Identification of antibody against SNRPB, small nuclear ribonucleoprotein-associated proteins B and B', as an autoantibody marker in Crohn's disease using an immunoproteomics approach

Wang, H., Demirkan, G., Bian, X., Wallstrom, G., Barker, K., Karthikeyan, K., Tang, Y., Pasha, S. F., Leighton, J. A., Qiu, J. & LaBaer, J., 2017, In : Journal of Crohn's and Colitis. 11, 7, p. 848-856 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Identification of antibody targets for tuberculosis serology using High-Density Nucleic Acid Programmable Protein Arrays

Song, L., Wallstrom, G., Yu, X., Hopper, M., Van Duine, J., Steel, J., Park, J., Wiktor, P., Kahn, P., Brunner, A., Wilson, D., Jenny-Avital, E. R., Qiu, J., LaBaer, J., Magee, D. & Achkar, J. M., Apr 1 2017, In : Molecular and Cellular Proteomics. 16, 4, p. S277-S289

Research output: Contribution to journalArticle

21 Scopus citations

Multiplexed Nucleic Acid programmable protein arrays

Yu, X., Song, L., Petritis, B., Bian, X., Wang, H., Viloria, J., Park, J., Bui, H., Li, H., Wang, J., Liu, L., Yang, L., Duan, H., McMurray, D. N., Achkar, J. M., Magee, D., Qiu, J. & LaBaer, J., 2017, In : Theranostics. 7, 16, 20151.

Research output: Contribution to journalArticle

9 Scopus citations

The Immune System and the Proteome

Marko-Varga, G. & LaBaer, J., Jan 6 2017, In : Journal of Proteome Research. 16, 1, p. 1 1 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays

Bian, X., Wasserfall, C., Wallstrom, G., Wang, J., Wang, H., Barker, K., Schatz, D., Atkinson, M., Qiu, J. & LaBaer, J., Jan 6 2017, In : Journal of Proteome Research. 16, 1, p. 195-203 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

A contra capture protein array platform for studying post-translationally modified (PTM) auto-antigenomes

Karthikeyan, K., Barker, K., Tang, Y., Kahn, P., Wiktor, P., Brunner, A., Knabben, V., Takulapalli, B., Buckner, J., Nepom, G., LaBaer, J. & Qiu, J., Jul 2016, In : Molecular and Cellular Proteomics. 15, 7, p. 2324-2337 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Advancing translational research with next-generation protein microarrays

Yu, X., Petritis, B. & LaBaer, J., Apr 1 2016, In : Proteomics. 16, 8, p. 1238-1250 13 p.

Research output: Contribution to journalReview article

10 Scopus citations

Comparative study of autoantibody responses between lung adenocarcinoma and benign pulmonary nodules

Wang, J., Shivakumar, S., Barker, K., Tang, Y., Wallstrom, G., Park, J., Tsay, J. C. J., Pass, H. I., Rom, W. N., LaBaer, J. & Qiu, J., Mar 23 2016, In : Journal of Thoracic Oncology. 11, 3, p. 334-345 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Immunoproteomic profiling of antiviral antibodies in new-onset type 1 diabetes using protein arrays

Bian, X., Wallstrom, G., Davis, A., Wang, J., Park, J., Throop, A., Steel, J., Yu, X., Wasserfall, C., Schatz, D., Atkinson, M., Qiu, J. & LaBaer, J., Jan 1 2016, In : Diabetes. 65, 1, p. 285-296 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Mapping transcription factor interactome networks using HaloTag protein arrays

Yazaki, J., Galli, M., Kim, A. Y., Nito, K., Aleman, F., Chang, K. N., Carvunis, A. R., Quan, R., Nguyen, H., Song, L., Alvarez, J. M., Huang, S. S. C., Chen, H., Ramachandran, N., Altmann, S., Gutiérrez, R. A., Hill, D. E., Schroeder, J. I., Chory, J., LaBaer, J. & 3 others, Vidal, M., Braun, P. & Ecker, J. R., Jul 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 29, p. E4238-E4247

Research output: Contribution to journalArticle

31 Scopus citations

Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers

Katchman, B. A., Barderas, R., Alam, R., Chowell, D., Field, M. S., Esserman, L. J., Wallstrom, G., LaBaer, J., Cramer, D. W., Hollingsworth, M. A. & Anderson, K., Jul 1 2016, In : Proteomics - Clinical Applications. 10, 7, p. 720-731 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

The ORFeome Collaboration: A genome-scale human ORF-clone resource

Wiemann, S., Pennacchio, C., Hu, Y., Hunter, P., Harbers, M., Amiet, A., Bethel, G., Busse, M., Carninci, P., Diekhans, M., Dunham, I., Hao, T., Harper, J. W., Hayashizaki, Y., Heil, O., Hennig, S., Hotz-Wagenblatt, A., Jang, W., Jöcker, A., Kawai, J. & 24 others, Koenig, C., Korn, B., Lambert, C., LeBeau, A., Lu, S., Maurer, J., Moore, T., Ohara, O., Park, J., Rolfs, A., Salehi-Ashtiani, K., Seiler, C., Simmons, B., Van Brabant Smith, A., Steel, J., Wagner, L., Weaver, T., Wellenreuther, R., Yang, S., Vidal, M., S Gerhard, D., LaBaer, J., Temple, G. & Hill, D. E., Feb 25 2016, In : Nature Methods. 13, 3, p. 191-192 2 p.

Research output: Contribution to journalLetter

47 Scopus citations
2015

Antiviral antibody profiling by high-density protein arrays

Bian, X., Wiktor, P., Kahn, P., Brunner, A., Khela, A., Karthikeyan, K., Barker, K., Yu, X., Magee, D., Wasserfall, C. H., Gibson, D., Rooney, M. E., Qiu, J. & LaBaer, J., Jun 1 2015, In : Proteomics. 15, 12, p. 2136-2145 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Autoantibody signature for the serologic detection of ovarian cancer

Anderson, K., Cramer, D. W., Sibani, S., Wallstrom, G., Wong, J., Park, J., Qiu, J., Vitonis, A. & LaBaer, J., Jan 2 2015, In : Journal of Proteome Research. 14, 1, p. 578-586 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

Biophysical characterization of a vaccine candidate against HIV-1: The transmembrane and membrane proximal domains of HIV-1 gp41 as a maltose binding protein fusion

Gong, Z., Martin-Garcia, J. M., Daskalova, S. M., Craciunescu, F. M., Song, L., Dörner, K., Hansen, D., Yang, J. H., LaBaer, J., Hogue, B., Leket-Mor, T. & Fromme, P., Aug 21 2015, In : PloS one. 10, 8, e0136507.

Research output: Contribution to journalArticle

3 Scopus citations

High-throughput identification of proteins with AMPylation using self-assembled human protein (NAPPA) microarrays

Yu, X. & LaBaer, J., May 6 2015, In : Nature Protocols. 10, 5, p. 756-767 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Host-pathogen interaction profiling using self-assembling human protein arrays

Yu, X., Decker, K. B., Barker, K., Neunuebel, M. R., Saul, J., Graves, M., Westcott, N., Hang, H., LaBaer, J., Qiu, J. & Machner, M. P., Apr 3 2015, In : Journal of Proteome Research. 14, 4, p. 1920-1936 17 p.

Research output: Contribution to journalArticle

27 Scopus citations

Integration of proteomics and transcriptomics data sets for the analysis of a lymphoma B-cell line in the context of the chromosome-centric human proteome project

Díez, P., Droste, C., Dégano, R. M., González-Muñoz, M., Ibarrola, N., Pérez-Andrés, M., Garin-Muga, A., Segura, V., Marko-Varga, G., LaBaer, J., Orfao, A., Corrales, F. J., De Las Rivas, J. & Fuentes, M., Sep 4 2015, In : Journal of Proteome Research. 14, 9, p. 3530-3540 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

In vitro transcription/translation system: A versatile tool in the search for missing proteins

Horvatovich, P., Végvári, Á., Saul, J., Park, J., Qiu, J., Syring, M., Pirrotte, P., Petritis, K., Tegeler, T. J., Aziz, M., Fuentes, M., Diez, P., Gonzalez-Gonzalez, M., Ibarrola, N., Droste, C., De Las Rivas, J., Gil, C., Clemente, F., Hernaez, M. L., Corrales, F. J. & 6 others, Nilsson, C. L., Berven, F. S., Bischoff, R., Fehniger, T. E., LaBaer, J. & Marko-Varga, G., Sep 4 2015, In : Journal of Proteome Research. 14, 9, p. 3441-3451 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Kinome-level screening identifies inhibition of polo-like kinase-1 (PLK1) as a target for enhancing non-viral transgene expression

Christensen, M. D., Elmer, J. J., Eaton, S., Gonzalez-Malerva, L., LaBaer, J. & Rege, K., Apr 28 2015, In : Journal of Controlled Release. 204, p. 20-29 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Microreactor array device

Wiktor, P., Brunner, A., Kahn, P., Qiu, J., Magee, D., Bian, X., Karthikeyan, K. & LaBaer, J., 2015, In : Scientific reports. 5, 8736.

Research output: Contribution to journalArticle

12 Scopus citations

Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays

Olia, A. S., Barker, K., McCullough, C. E., Tang, H. Y., Speicher, D. W., Qiu, J., LaBaer, J. & Marmorstein, R., Sep 18 2015, In : ACS Chemical Biology. 10, 9, p. 2034-2047 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

Plasma autoantibodies associated with basal-like breast cancers

Wang, J., Figueroa, J. D., Wallstrom, G., Barker, K., Park, J., Demirkan, G., Lissowska, J., Anderson, K., Qiu, J. & LaBaer, J., Sep 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 9, p. 1332-1340 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Recent advances in proteomics applied to elucidate the role of environmental impacts on human health and organismal function

Halden, R., Hartmann, E. M., Denslow, N. D., Haynes, P. A. & LaBaer, J., Jan 2 2015, In : Journal of Proteome Research. 14, 1, p. 1-4 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Site-specific recombinational cloning using gateway and in-fusion cloning schemes

Park, J., Throop, A. L. & LaBaer, J., Jan 1 2015, In : Current Protocols in Molecular Biology. 2015, p. 3.20.1-3.20.23

Research output: Contribution to journalArticle

8 Scopus citations

Sustainability in a Hospital-Based Biobank and University-Based DNA Biorepository: Strategic Roadmaps

Seiler, C. Y., Eschbacher, J., Bowser, R. & LaBaer, J., Dec 1 2015, In : Biopreservation and Biobanking. 13, 6, p. 401-409 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome

Nilsson, C. L., Mostovenko, E., Lichti, C. F., Ruggles, K., Fenyö, D., Rosenbloom, K. R., Hancock, W. S., Paik, Y. K., Omenn, G. S., LaBaer, J., Kroes, R. A., Uhlén, M., Hober, S., Végvári, Á., Andrén, P. E., Sulman, E. P., Lang, F. F., Fuentes, M., Carlsohn, E., Emmett, M. R. & 4 others, Moskal, J. R., Berven, F. S., Fehniger, T. E. & Marko-Varga, G., Feb 6 2015, In : Journal of Proteome Research. 14, 2, p. 603-608 6 p.

Research output: Contribution to journalArticle

15 Scopus citations