John Spence

CrystallographyInIndia

5/1/18 → 4/30/19

Project: Research project

radiation damage

pulse duration

damage

biology

molecules

3D nanoprinter for X-ray laser bioparticle delivery

Spence, J., Weierstall, U., Fromme, P., Hogue, B., Kirian, R. & Ros, A.

NSF-BIO: Division of Biological Infrastructure (DBI)

4/1/16 → 3/31/17

Project: Research project

Nozzles

Proteins

3D printers

Nanocrystals

X ray lasers

MRI: Acquisition of Cryo-EM for Southwest Regional Center

Spence, J., Westerhoff, P., Vermaas, W., Frasch, W., Roberson, R., Carpenter, R., Rez, P., Weierstall, U., Muthuswamy, J., Leket-Mor, T., Wachter, R., Fromme, P., Hogue, B., Stabenfeldt, S., Mason, H., Yan, H., Rittmann, B., Torres, C., Wiktor, P., Rege, K., Halden, R., Ros, R., Ros, A., LaBaer, J., Olive, M., Liu, J., Van Horn, W. & Liu, W.

9/1/15 → 8/31/18

Project: Research project

Cryoelectron Microscopy

Electrons

Proteins

Electron Microscopy

Scanning Transmission Electron Microscopy

(Flinn-JL) Establishment of a high throughput protein production center to empower translational research in Arizona (ASUF 30005389)

LaBaer, J., Spence, J. & Fromme, P.

Flinn Foundation

10/1/14 → 9/30/19

Project: Research project

proteins

proteomics

Biological Sciences

phenotype

drugs

Tracking Conformational States in Enzyme Catalysts Using Correlated X-ray Scatter

Spence, J. & Weierstall, U.

6/4/12 → 5/31/16

Project: Research project

Coherent Diffractive Imaging of Viruses

OTHER: Foreign Other

11/1/11 → 10/31/14

Project: Research project

viruses

diffraction patterns

genome

coherent light

marking

EAGER Renewal: Femtosecond Virus Structure

Weierstall, U., Schmidt, K., Spence, J. & Hogue, B.

8/1/11 → 7/31/14

Project: Research project

BioFEL Workshop at Lawrence Berekeley Laboratory on January 18-21, 2011

HHS-NIH: National Institute of General Medical Sciences (NIGMS)

3/1/11 → 2/29/12

Project: Research project

Femtosecond Nano-Crystallography of Membrane Proteins

Fromme, P., Schmidt, K., Spence, J., Weierstall, U. & Ros, A.

9/30/10 → 5/31/15

Project: Research project

Crystallography

Membrane Proteins

Microcrystals

X rays

Photosystem I Protein Complex

Dynamics of electron transfer-PSIFerredoxin

Spence, J., Schmidt, K., Weierstall, U. & Fromme, P.

9/1/10 → 8/31/14

Project: Research project

electron transfer

proteins

coherent light

light sources

proposals

Enhanced Functionality for Materials Analysis in the DTEM

9/30/09 → 9/29/13

Project: Research project

transparence

glass

lasers

energy dissipation

silicates

Fluctuation X-ray diffraction of membrane proteins in solution

Spence, J. & Fromme, P.

9/1/09 → 8/31/11

Project: Research project

EAGER: Femtosecond Virus Structure

Weierstall, U., Schmidt, K., Spence, J. & Hogue, B.

8/1/09 → 7/31/11

Project: Research project

viruses

x rays

diffraction patterns

free electron lasers

pulses

MRI: Acquisition of an aberration corrected high resolution analytical transmission electron micro for advanced materials research

Carpenter, R., Sharp, T., McCartney, M., Buseck, P. R., Spence, J., Smith, D., Rez, P., Crozier, P., Newman, N., Drucker, J. & Treacy, M.

10/1/08 → 8/31/14

Project: Research project

Protein structure for new drugs

DOD-NAVY: Office of Naval Research (ONR)

7/1/08 → 3/31/09

Project: Research project

Laser Aligned Protein Beams

NSF-MPS: Division of Physics (PHY)

8/1/07 → 7/31/11

Project: Research project

Lasers

Proteins

Photosystem I Protein Complex

Crystallization

Crystallites

Protein Beam Diffraction

Spence, J., Schmidt, K. & Weierstall, U.

10/1/06 → 9/30/09

Project: Research project

Time-Resolved EELS of Photonic Crystals and Glasses

7/15/06 → 6/30/11

Project: Research project

Enhanced Functionality for Materials Analysis in the DTEM

3/1/06 → 2/28/09

Project: Research project

Protein Structure for Drugs

DOD-ARMY-ARL: Army Research Office (ARO)

4/1/05 → 6/30/08

Project: Research project

Serial Crystallography

Spence, J., Schmidt, K., Weierstall, U. & Fromme, P.

8/1/04 → 7/31/06

Project: Research project

ORDERING/LITHOGRAPHY IN GLASSES/ALLOYS

Spence, J. & Weierstall, U.

5/1/03 → 4/30/07

Project: Research project

ELECTRONIC OXIDES

9/1/02 → 5/31/13

Project: Research project

EQUIPMENT FOR FUNCTIONAL ORGANIC MONOLAYERS

DOD-ARMY-ARL: Army Research Office (ARO)

4/1/01 → 9/30/02

Project: Research project

FUNCTIONAL ORGANIC MONOLAYERS

DOD-ARMY-ARL: Army Research Office (ARO)

9/1/00 → 10/31/05

Project: Research project

KINKS AND SURFACE POTENTIAL

12/1/98 → 11/30/02

Project: Research project

Active

Mid-Scale RI-1 (M1:DP): Compact X-ray Free-Electron Laser Project (CXFEL)

Graves, W., Schmidt, K., Spence, J., Weierstall, U., Thornton, T., Fromme, P., Kirian, R., Ros, A., Tongay, S., Liu, W., Erten, O., Sanchez Botana, A., Karkare, S. & Messerschmidt, M.

10/1/19 → 9/30/22

Project: Research project

Visualizing chemical bonding in biological macromolecules by microcrystal electron diffraction

Nannenga, B. & Spence, J.

9/20/19 → 7/31/21

Project: Research project

Nanopatterned Electron Beams for Coherent Radiation Emission

Graves, W. & Spence, J.

NSF-BIO: Division of Biological Infrastructure (DBI)

8/15/16 → 7/31/20

Project: Research project

coherent radiation

electron beams

radiation

x rays

accelerators

ABI Innovation: New Algorithms for Biological X-ray Free Electron Laser Data

Schmidt, K., Spence, J., Weierstall, U. & Kirian, R.

8/1/16 → 7/31/20

Project: Research project

Center for Membrane Protein Drug Discovery (MEDD)

Fromme, P., Tao, N., Spence, J., Weierstall, U., Nannenga, B., Fromme, R., Wiktor, P., Kirian, R., Ros, A., Wang, S., LaBaer, J., Anderson, K., Qiu, J., Van Horn, W., Hansen, D., Sayres, S., Liu, W., Mills, J. & Graves, W.