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Research Output 1993 2019

  • 1088 Citations
  • 17 h-Index
  • 48 Article
  • 23 Conference contribution
  • 3 Chapter
2019

Design and development of microscale thickness shear mode (TSM) resonators for sensing neuronal adhesion

Khraiche, M. L., Rogul, J. & Muthuswamy, J., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 518.

Research output: Contribution to journalArticle

Open Access
Electrodes
Neurons
Cell Culture Techniques
Population
Equipment and Supplies
2018
1 Citation (Scopus)

Photoacoustic micropipette

Miranda, C., Sampath Kumar, S., Muthuswamy, J. & Smith, B., Dec 24 2018, In : Applied Physics Letters. 113, 26, 264103.

Research output: Contribution to journalArticle

neurons
recording
glass electrodes
borosilicate glass
navigation
1 Citation (Scopus)

Remote stimulation of sciatic nerve using cuff electrodes and implanted diodes

Sridharan, A., Chirania, S., Towe, B. C. & Muthuswamy, J., Nov 14 2018, In : Micromachines. 9, 11, 595.

Research output: Contribution to journalArticle

Diodes
Electrodes
Muscle
Rats
Chemical activation
2016
1 Citation (Scopus)

Autonomous control for mechanically stable navigation of microscale implants in brain tissue to record neural activity

Anand, S., Kumar, S. S. & Muthuswamy, J., Aug 1 2016, In : Biomedical Microdevices. 18, 4, 72.

Research output: Contribution to journalArticle

Microelectrodes
Brain
Navigation
Tissue
Signal-To-Noise Ratio
10 Citations (Scopus)

Finite element modeling of human brain response to football helmet impacts

Darling, T., Muthuswamy, J. & Rajan, S., Feb 11 2016, (Accepted/In press) In : Computer Methods in Biomechanics and Biomedical Engineering. p. 1-11 11 p.

Research output: Contribution to journalArticle

Brain
Strain rate
Cell death
Loads (forces)
3 Citations (Scopus)

Optogenetic neurostimulation of auricular vagus using flexible OLED display technology to treat chronic inflammatory disease and mental health disorders

Smith, J., Shah, A., Lee, Y. K., O'Brien, B., Kullman, D., Sridharan, A., Muthuswamy, J. & Blain Christen, J., May 26 2016, In : Electronics Letters. 52, 11, p. 900-902 3 p.

Research output: Contribution to journalArticle

Organic light emitting diodes (OLED)
Display devices
Health
Tissue
Plastics
4 Citations (Scopus)

Sustained elevation of activity of developing neurons grown on polyimide microelectrode arrays (MEA) in response to ultrasound exposure

Khraiche, M. L., Phillips, W. B., Jackson, N. & Muthuswamy, J., Oct 22 2016, (Accepted/In press) In : Microsystem Technologies. p. 1-13 13 p.

Research output: Contribution to journalArticle

Microelectrodes
neurons
polyimides
Polyimides
Neurons
2015
31 Citations (Scopus)

Compliant intracortical implants reduce strains and strain rates in brain tissue in vivo

Sridharan, A., Nguyen, J. K., Capadona, J. R. & Muthuswamy, J., Jun 1 2015, In : Journal of Neural Engineering. 12, 3, 036002.

Research output: Contribution to journalArticle

Silicon
Strain rate
Brain
Polyvinyl acetates
Tissue
2013
39 Citations (Scopus)

Long-term changes in the material properties of brain tissue at the implant-tissue interface

Sridharan, A., Rajan, S. & Muthuswamy, J., Dec 2013, In : Journal of Neural Engineering. 10, 6, 066001.

Research output: Contribution to journalArticle

Microelectrodes
Brain
Materials properties
Tissue
Elastic moduli
4 Citations (Scopus)

Voltage preconditioning allows modulated gene expression in neurons using PEI-complexed siRNA

Sridharan, A., Patel, C. & Muthuswamy, J., 2013, In : Molecular Therapy - Nucleic Acids. 2, e82.

Research output: Contribution to journalArticle

Polyethyleneimine
Small Interfering RNA
Gene Expression
Neurons
Transfection
2012
10 Citations (Scopus)

Electrothermal microactuators with peg drive improve performance for brain implant applications

Anand, S., Sutanto, J., Baker, M. S., Okandan, M. & Muthuswamy, J., 2012, In : Journal of Microelectromechanical Systems. 21, 5, p. 1172-1186 15 p., 6239549.

Research output: Contribution to journalArticle

Microactuators
Microelectrodes
Brain
MEMS
Actuators

Flip-chip based packaging for linear ratcheting microactuators enables 3d stacks of moveble microelectrodes for the brain

Sutanto, J., Anand, S., Korb, R., Zhou, L., Okandan, M., Baker, M. & Muthuswamy, J., 2012, Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop. Transducer Research Foundation, p. 157-160 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microactuators
Microelectrodes
MEMS
Brain
Packaging
1 Citation (Scopus)
Microelectrodes
Small Interfering RNA
Transfection
Electroporation
Electrodes
Microelectrodes
Small Interfering RNA
Transfection
Electroporation
Electrodes
1 Citation (Scopus)
Biochips
Time measurement
Integrins
Neurons
Adhesion
13 Citations (Scopus)

Novel first-level interconnect techniques for flip chip on MEMS devices

Sutanto, J., Anand, S., Patel, C. & Muthuswamy, J., Feb 2012, In : Journal of Microelectromechanical Systems. 21, 1, p. 132-144 13 p., 6069517.

Research output: Contribution to journalArticle

MEMS
Soldering alloys
Aspect ratio
Packaging
Microelectrodes
7 Citations (Scopus)

Packaging and non-hermetic encapsulation technology for flip chip on implantable MEMS devices

Sutanto, J., Anand, S., Sridharan, A., Korb, R., Zhou, L., Baker, M. S., Okandan, M. & Muthuswamy, J., 2012, In : Journal of Microelectromechanical Systems. 21, 4, p. 882-896 15 p., 6182573.

Research output: Contribution to journalArticle

Encapsulation
MEMS
Microelectrodes
Packaging
Cerebrospinal fluid
2011
11 Citations (Scopus)

Adaptive movable neural interfaces for monitoring single neurons in the brain

Muthuswamy, J., Anand, S. & Sridharan, A., 2011, In : Frontiers in Neuroscience. SEP, Article 94.

Research output: Contribution to journalArticle

Microelectrodes
Neurons
Brain
Technology
Electrodes

Gene Injection and Manipulation Using CMOS-Based Technologies

Sridharan, A. & Muthuswamy, J., May 3 2011, CMOS Biomicrosystems: Where Electronics Meet Biology. John Wiley and Sons, p. 407-456 50 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genes

Implantable microtechnologies for the brain: Challenges and strategies for reliable operation

Muthuswamy, J., Anand, S., Sutanto, J., Baker, M. & Okandan, M., 2011, IEEE International Reliability Physics Symposium Proceedings. 5784480

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neurons
Brain
Microelectrodes
Packaging
Microactuators
2010
5 Citations (Scopus)

Highly doped polycrystalline silicon microelectrodes reduce noise in neuronal recordings in vivo

Saha, R., Jackson, N., Patel, C. & Muthuswamy, J., Oct 2010, In : IEEE Transactions on Neural Systems and Rehabilitation Engineering. 18, 5, p. 489-497 9 p., 5524035.

Research output: Contribution to journalArticle

Microelectrodes
Silicon
Polysilicon
Noise
Tungsten
21 Citations (Scopus)

Long-term neural recordings using MEMS based movable microelectrodes in the brain

Jackson, N., Sridharan, A., Anand, S., Baker, M., Okandan, M. & Muthuswamy, J., Jun 18 2010, In : Frontiers in Neuroengineering. 3, JUN, 10.

Research output: Contribution to journalArticle

Micro-Electrical-Mechanical Systems
Microelectrodes
Brain
Signal-To-Noise Ratio
Signal to noise ratio
2009
19 Citations (Scopus)

Assessment of gliosis around moveable implants in the brain

Stice, P. & Muthuswamy, J., 2009, In : Journal of Neural Engineering. 6, 4, 046004.

Research output: Contribution to journalArticle

Gliosis
Microelectrodes
Brain
Glial Fibrillary Acidic Protein
Animals

Biohybrid photoelectrochemical nanoengineered interfaces

Sridharan, A., Muthuswamy, J. & Pizziconi, V., 2009, Materials Research Society Symposium Proceedings. Vol. 1191. p. 23-28 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

electrochemical cells
stimulation
Electrochemical cells
electrodes
biomimetics
11 Citations (Scopus)

Early onset of electrical activity in developing neurons cultured on carbon nanotube immobilized microelectrodes

Khraiche, M. L., Jackson, N. & Muthuswamy, J., 2009, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. p. 777-780 4 p. 5333590

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Carbon Nanotubes
Microelectrodes
Neurons
Carbon nanotubes
Adhesion
28 Citations (Scopus)
Chip scale packages
Microelectrodes
MEMS
Brain
Packaging
8 Citations (Scopus)

Nonhermetic encapsulation materials for mems-based movable microelectrodes for long-term implantation in the brain

Jackson, N., Anand, S., Okandan, M. & Muthuswamy, J., Dec 2009, In : Journal of Microelectromechanical Systems. 18, 6, p. 1234-1245 12 p., 5280304.

Research output: Contribution to journalArticle

Microelectrodes
Encapsulation
Brain
Silicones
Gels
4 Citations (Scopus)

Optoelectronic energy transfer at novel biohybrid interfaces using light harvesting complexes from chloroflexus aurantiacus

Sridharan, A., Muthuswamy, J. & Pizziconi, V., Jun 2 2009, In : Langmuir. 25, 11, p. 6508-6516 9 p.

Research output: Contribution to journalArticle

Optoelectronic devices
Energy transfer
Photocurrents
energy transfer
photocurrents
2008
14 Citations (Scopus)

Artificial dural sealant that allows multiple penetrations of implantable brain probes

Jackson, N. & Muthuswamy, J., Jun 15 2008, In : Journal of Neuroscience Methods. 171, 1, p. 147-152 6 p.

Research output: Contribution to journalArticle

Silicone Gels
Gels
Brain
Neurophysiology
Craniotomy

Flexible interconnect and packaging for MEMS moveable neural microelectrodes

Jackson, N. & Muthuswamy, J., 2008, Proceedings - 2008 International Symposium on Microelectronics, IMAPS 2008. p. 247-251 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microelectrodes
MEMS
Packaging
Gold
Electrodes
10 Citations (Scopus)

Immobilization of functional light antenna structures derived from the filamentous green bacterium Chloroflexus aurantiacus

Sridharan, A., Muthuswamy, J., LaBelle, J. & Pizziconi, V., Aug 5 2008, In : Langmuir. 24, 15, p. 8078-8089 12 p.

Research output: Contribution to journalArticle

immobilization
bacteria
Electrochemical cells
electrochemical cells
Bacteria
15 Citations (Scopus)

Immunosensor for detection of inhibitory neurotransmitter γ-aminobutyric acid using quartz crystal microbalance

Wang, T. & Muthuswamy, J., Nov 15 2008, In : Analytical Chemistry. 80, 22, p. 8576-8582 7 p.

Research output: Contribution to journalArticle

Aminobutyrates
Immunosensors
Quartz crystal microbalances
gamma-Aminobutyric Acid
Neurotransmitter Agents
13 Citations (Scopus)

Microelectrode array (MEA) platform for targeted neuronal transfection and recording

Jain, T. & Muthuswamy, J., Feb 2008, In : IEEE Transactions on Biomedical Engineering. 55, 2, p. 827-832 6 p.

Research output: Contribution to journalArticle

Microelectrodes
Neurons
Molecules
Genes
13 Citations (Scopus)

Ultrasound induced increase in excitability of single neurons

Khraiche, M. L., Phillips, W. B., Jackson, N. & Muthuswamy, J., 2008, Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology". p. 4246-4249 4 p. 4650147

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neurons
Ultrasonics
Hot Temperature
Brain
Thermal effects
Neurons
Ultrasonics
Hot Temperature
Brain
Thermal effects
2007
33 Citations (Scopus)
Nucleic acids
Nucleic Acids
Transfection
Molecules
Microelectrodes
5 Citations (Scopus)

Long-term cortical recordings with microactuated microelectrodes

Jackson, N., Stice, P., Okandan, M. & Muthuswamy, J., 2007, Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering. p. 141-143 3 p. 4227237

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microelectrodes
Technology
Rodentia
Microactuators
Polysilicon
20 Citations (Scopus)

Microsystem for transfection of exogenous molecules with spatio-temporal control into adherent cells

Jain, T. & Muthuswamy, J., Jan 15 2007, In : Biosensors and Bioelectronics. 22, 6, p. 863-870 8 p.

Research output: Contribution to journalArticle

Microelectrodes
Microsystems
Transfection
Molecules
Electroporation

Spatio-temporally controlled transfection of nucleic acid payloads in cell-culture

Jain, T. & Muthuswamy, J., 2007, Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering. p. 284-286 3 p. 4227271

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nucleic acids
Cell culture
Nucleic Acids
Transfection
Cell Culture Techniques
8 Citations (Scopus)
Polysilicon
Electric Stimulation
Neurons
Electric Impedance
Micro-Electrical-Mechanical Systems
46 Citations (Scopus)

Thin microelectrodes reduce GFAP expression in the implant site in rodent somatosensory cortex

Stice, P., Gilletti, A., Panitch, A. & Muthuswamy, J., Jun 1 2007, In : Journal of Neural Engineering. 4, 2, p. 42-53 12 p., 005.

Research output: Contribution to journalArticle

Somatosensory Cortex
Microelectrodes
glycolic acid
Neuroglia
Rodentia
2006
138 Citations (Scopus)

Brain micromotion around implants in the rodent somatosensory cortex

Gilletti, A. & Muthuswamy, J., Sep 1 2006, In : Journal of Neural Engineering. 3, 3, p. 189-195 7 p., 001.

Research output: Contribution to journalArticle

Somatosensory Cortex
Rodentia
Brain
Tissue
Rats
3 Citations (Scopus)

Immobilization and characterization of γ-Aminobutyric acid on gold surface

Wang, T., Ehteshami, G., Massia, S. & Muthuswamy, J., Oct 2006, In : Journal of Biomedical Materials Research - Part A. 79, 1, p. 201-209 9 p.

Research output: Contribution to journalArticle

Aminobutyrates
Gold
gamma-Aminobutyric Acid
Antibodies
Acids
2005
13 Citations (Scopus)

Acoustic sensor for monitoring adhesion of Neuro-2A cells in real-time

Khraiche, M. L., Zhou, A. & Muthuswamy, J., May 15 2005, In : Journal of Neuroscience Methods. 144, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Acoustics
Neurons
Quartz
Gold
Electrodes
49 Citations (Scopus)

An array of microactuated microelectrodes for monitoring single-neuronal activity in rodents

Muthuswamy, J., Okandan, M., Gilletti, A., Baker, M. S. & Jain, T., Aug 2005, In : IEEE Transactions on Biomedical Engineering. 52, 8, p. 1470-1477 8 p.

Research output: Contribution to journalArticle

Microelectrodes
Monitoring
Microactuators
Brain
Insulation
41 Citations (Scopus)

Electrostatic microactuators for precise positioning of neural microelectrodes

Muthuswamy, J., Okandan, M., Jain, T. & Gilletti, A., Oct 2005, In : IEEE Transactions on Biomedical Engineering. 52, 10, p. 1748-1755 8 p.

Research output: Contribution to journalArticle

Microactuators
Microelectrodes
Electrostatics
Brain
Neurons

Movable microprobes for the brain

Muthuswamy, J., Okandan, M., Gilletti, A., Baker, M., Jain, T. & Jackson, N., 2005, 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology. Vol. 2005. p. 86-87 2 p. 1548390

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microactuators
Microelectrodes
Brain
Neurons
Electrostatics
17 Citations (Scopus)

Single neuronal recordings using surface micromachined polysilicon microelectrodes

Muthuswamy, J., Okandan, M. & Jackson, N., Mar 15 2005, In : Journal of Neuroscience Methods. 142, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Microelectrodes
Microtechnology
Silicon
Central Nervous System
Neurons
9 Citations (Scopus)

Tissue micromotion induced stress around brain implants

Muthuswamy, J., Saha, R. & Gilletti, A., 2005, 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology. Vol. 2005. p. 102-103 2 p. 1548395

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brain
Tissue
Rats
Shear stress
Transducers
2004
22 Citations (Scopus)

Acoustic biosensor for monitoring antibody immobilization and neurotransmitter GABA in real-time

Zhou, A. & Muthuswamy, J., Jun 15 2004, In : Sensors and Actuators, B: Chemical. 101, 1-2, p. 8-19 12 p.

Research output: Contribution to journalArticle

neurotransmitters
Immunosensors
antibodies
immobilization
bioinstrumentation