• 2074 Citations
  • 21 h-Index
19992023
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Research Output 1999 2019

  • 2074 Citations
  • 21 h-Index
  • 33 Article
  • 2 Letter
2019
1 Citation (Scopus)

A human organotypic microfluidic tumor model permits investigation of the interplay between patient-derived fibroblasts and breast cancer cells

Truong, D. D., Kratz, A., Park, J., Barrientos, E. S., Saini, H., Nguyen, T., Pockaj, B., Mouneimne, G., LaBaer, J. & Nikkhah, M., Jun 15 2019, In : Cancer Research. 79, 12, p. 3139-3151 13 p.

Research output: Contribution to journalArticle

Microfluidics
Fibroblasts
Breast Neoplasms
Neoplasms
Glycoproteins
2 Citations (Scopus)

Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes

Ferdosi, S. R., Ewaisha, R., Moghadam, F., Krishna, S., Park, J., Ebrahimkhani, M. R., Kiani, S. & Anderson, K., Dec 1 2019, In : Nature communications. 10, 1, 1842.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
T-Lymphocyte Epitopes
T-cells
Streptococcus pyogenes
T-Lymphocytes
2018
4 Citations (Scopus)

Gene expression profiling and assessment of vitamin D and serotonin pathway variations in patients with irritable bowel syndrome

Dussik, C. M., Hockley, M., Grozic, A., Kaneko, I., Zhang, L., Sabir, M. S., Park, J., Wang, J., Nickerson, C., Yale, S. H., Rall, C. J., Foxx-Orenstein, A. E., Borror, C. M., Sandrin, T. & Jurutka, P., Jan 1 2018, In : Journal of Neurogastroenterology and Motility. 24, 1, p. 96-106 11 p.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Gene Expression Profiling
Vitamin D
Serotonin
Tryptophan Hydroxylase
6 Citations (Scopus)

Human papilloma virus specific immunogenicity and dysfunction of CD8+ T cells in head and neck cancer

Krishna, S., Ulrich, P., Wilson, E., Parikh, F., Narang, P., Yang, S., Read, A. K., Kim-Schulze, S., Park, J., Posner, M., Wilson Sayres, M., Sikora, A. & Anderson, K., Nov 1 2018, In : Cancer Research. 78, 21, p. 6159-6170 12 p.

Research output: Contribution to journalArticle

Papillomaviridae
Head and Neck Neoplasms
T-Lymphocytes
Human papillomavirus 16
Antigens
7 Citations (Scopus)

Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner

Rauf, F., Festa, F., Park, J., Magee, D., Eaton, S., Rinaldi, C., Betanzos, C. M., Gonzalez-Malerva, L. & LaBaer, J., Feb 5 2018, (Accepted/In press) In : Oncogene. p. 1-14 14 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Cell Line
Protein Array Analysis
Medical Oncology
2017
6 Citations (Scopus)

Developing Human Radiation Biodosimetry Models: Testing Cross-Species Conversion Approaches Using an Ex Vivo Model System

Park, J., Paul, S., Briones, N., Zeng, J., Gillis, K., Wallstrom, G., LaBaer, J. & Amundson, S. A., Jun 1 2017, In : Radiation Research. 187, 6, p. 708-721 14 p.

Research output: Contribution to journalArticle

primates
Primates
genes
Radiation
radiation
14 Citations (Scopus)

Identification of antibody targets for tuberculosis serology using High-Density Nucleic Acid Programmable Protein Arrays

Song, L., Wallstrom, G., Yu, X., Hopper, M., Van Duine, J., Steel, J., Park, J., Wiktor, P., Kahn, P., Brunner, A., Wilson, D., Jenny-Avital, E. R., Qiu, J., LaBaer, J., Magee, D. & Achkar, J. M., Apr 1 2017, In : Molecular and Cellular Proteomics. 16, 4, p. S277-S289

Research output: Contribution to journalArticle

Protein Array Analysis
Serology
Nucleic Acids
Tuberculosis
HIV
22 Citations (Scopus)

Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage

Kim, K. H., Kim, Y. H., Son, J. E., Lee, J. H., Kim, S., Choe, M. S., Moon, J. H., Zhong, J., Fu, K., Lenglin, F., Yoo, J. A., Bilan, P. J., Klip, A., Nagy, A., Kim, J. R., Park, J., Hussein, S. M. I., Doh, K. O., Hui, C. C. & Sung, H. K., Nov 1 2017, In : Cell Research. 27, 11, p. 1309-1326 18 p.

Research output: Contribution to journalArticle

Macrophage Activation
Thermogenesis
Vascular Endothelial Growth Factor A
Fasting
Homeostasis
6 Citations (Scopus)

Multiplexed Nucleic Acid programmable protein arrays

Yu, X., Song, L., Petritis, B., Bian, X., Wang, H., Viloria, J., Park, J., Bui, H., Li, H., Wang, J., Liu, L., Yang, L., Duan, H., McMurray, D. N., Achkar, J. M., Magee, D., Qiu, J. & LaBaer, J., 2017, In : Theranostics. 7, 16, 20151.

Research output: Contribution to journalArticle

Protein Array Analysis
Nucleic Acids
Proteins
Translational Medical Research
Proteome
2016
16 Citations (Scopus)

Comparative study of autoantibody responses between lung adenocarcinoma and benign pulmonary nodules

Wang, J., Shivakumar, S., Barker, K., Tang, Y., Wallstrom, G., Park, J., Tsay, J. C. J., Pass, H. I., Rom, W. N., LaBaer, J. & Qiu, J., Mar 23 2016, In : Journal of Thoracic Oncology. 11, 3, p. 334-345 12 p.

Research output: Contribution to journalArticle

Autoantibodies
Lung Neoplasms
Lung
Tomography
Keratin-8
23 Citations (Scopus)

Immunoproteomic profiling of antiviral antibodies in new-onset type 1 diabetes using protein arrays

Bian, X., Wallstrom, G., Davis, A., Wang, J., Park, J., Throop, A., Steel, J., Yu, X., Wasserfall, C., Schatz, D., Atkinson, M., Qiu, J. & LaBaer, J., Jan 1 2016, In : Diabetes. 65, 1, p. 285-296 12 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Type 1 Diabetes Mellitus
Antiviral Agents
Virus Diseases
Antibodies
32 Citations (Scopus)

The ORFeome Collaboration: A genome-scale human ORF-clone resource

Wiemann, S., Pennacchio, C., Hu, Y., Hunter, P., Harbers, M., Amiet, A., Bethel, G., Busse, M., Carninci, P., Diekhans, M., Dunham, I., Hao, T., Harper, J. W., Hayashizaki, Y., Heil, O., Hennig, S., Hotz-Wagenblatt, A., Jang, W., Jöcker, A., Kawai, J. & 24 others, Koenig, C., Korn, B., Lambert, C., LeBeau, A., Lu, S., Maurer, J., Moore, T., Ohara, O., Park, J., Rolfs, A., Salehi-Ashtiani, K., Seiler, C., Simmons, B., Van Brabant Smith, A., Steel, J., Wagner, L., Weaver, T., Wellenreuther, R., Yang, S., Vidal, M., S Gerhard, D., LaBaer, J., Temple, G. & Hill, D. E., Feb 25 2016, In : Nature Methods. 13, 3, p. 191-192 2 p.

Research output: Contribution to journalLetter

2015
6 Citations (Scopus)

A multidisciplinary biospecimen bank of renal cell carcinomas compatible with discovery platforms at Mayo Clinic, Scottsdale, Arizona

Ho, T. H., Nateras, R. N., Yan, H., Park, J., Jensen, S., Borges, C., Lee, J. H., Champion, M. D., Tibes, R., Bryce, A. H., Carballido, E. M., Todd, M. A., Joseph, R. W., Wong, W. W., Parker, A. S., Stanton, M. L. & Castle, E. P., Jul 16 2015, In : PLoS One. 10, 7, e0132831.

Research output: Contribution to journalArticle

kidney cells
Renal Cell Carcinoma
carcinoma
Cells
RNA
43 Citations (Scopus)

Autoantibody signature for the serologic detection of ovarian cancer

Anderson, K., Cramer, D. W., Sibani, S., Wallstrom, G., Wong, J., Park, J., Qiu, J., Vitonis, A. & LaBaer, J., Jan 2 2015, In : Journal of Proteome Research. 14, 1, p. 578-586 9 p.

Research output: Contribution to journalArticle

Autoantibodies
Ovarian Neoplasms
Biomarkers
Serum
Area Under Curve
8 Citations (Scopus)

In vitro transcription/translation system: A versatile tool in the search for missing proteins

Horvatovich, P., Végvári, Á., Saul, J., Park, J., Qiu, J., Syring, M., Pirrotte, P., Petritis, K., Tegeler, T. J., Aziz, M., Fuentes, M., Diez, P., Gonzalez-Gonzalez, M., Ibarrola, N., Droste, C., De Las Rivas, J., Gil, C., Clemente, F., Hernaez, M. L., Corrales, F. J. & 6 others, Nilsson, C. L., Berven, F. S., Bischoff, R., Fehniger, T. E., LaBaer, J. & Marko-Varga, G., Sep 4 2015, In : Journal of Proteome Research. 14, 9, p. 3441-3451 11 p.

Research output: Contribution to journalArticle

Transcription
Proteins
Chromosomes
Human Chromosomes
Proteome
23 Citations (Scopus)

Plasma autoantibodies associated with basal-like breast cancers

Wang, J., Figueroa, J. D., Wallstrom, G., Barker, K., Park, J., Demirkan, G., Lissowska, J., Anderson, K., Qiu, J. & LaBaer, J., Sep 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 9, p. 1332-1340 9 p.

Research output: Contribution to journalArticle

Autoantibodies
Breast Neoplasms
Confidence Intervals
Protein Array Analysis
Disease Management
2014
25 Citations (Scopus)

Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based Detection of Global Pathogen-host AMPylation on Self-assembled Human Protein Microarrays

Yu, X., Woolery, A. R., Luong, P., Hao, Y. H., Grammel, M., Westcott, N., Park, J., Wang, J., Bian, X., Demirkan, G., Hang, H. C., Orth, K. & LaBaer, J., Nov 1 2014, In : Molecular and Cellular Proteomics. 13, 11, p. 3164-3176 13 p.

Research output: Contribution to journalArticle

Click Chemistry
Protein Array Analysis
Alkynes
Azides
Cycloaddition
86 Citations (Scopus)

DNASU plasmid and PSI: Biology-Materials repositories: Resources to accelerate biological research

Seiler, C. Y., Park, J., Sharma, A., Hunter, P., Surapaneni, P., Sedillo, C., Field, J., Algar, R., Price, A., Steel, J., Throop, A., Fiacco, M. & LaBaer, J., Jan 1 2014, In : Nucleic Acids Research. 42, D1

Research output: Contribution to journalArticle

Plasmids
Research
National Institute of General Medical Sciences (U.S.)
Proteins
Research Personnel
17 Citations (Scopus)

Exploration of panviral proteome: High-throughput cloning and functional implications in virus-host interactions

Yu, X., Bian, X., Throop, A., Song, L., Del Moral, L., Park, J., Seiler, C., Fiacco, M., Steel, J., Hunter, P., Saul, J., Wang, J., Qiu, J., Pipas, J. M. & LaBaer, J., 2014, In : Theranostics. 4, 8, p. 808-822 15 p.

Research output: Contribution to journalArticle

Proteome
Open Reading Frames
Organism Cloning
Viral Proteins
Viruses
2013
134 Citations (Scopus)

Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis

Sung, H. K., Doh, K. O., Son, J. E., Park, J., Bae, Y., Choi, S., Nelson, S. M. L., Cowling, R., Nagy, K., Michael, I. P., Koh, G. Y., Adamson, S. L., Pawson, T. & Nagy, A., Jan 8 2013, In : Cell Metabolism. 17, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Homeostasis
High Fat Diet
Adipose Tissue
Doxycycline
27 Citations (Scopus)

A versatile protein microarray platform enabling antibody profiling against denatured proteins

Wang, J., Barker, K., Steel, J., Park, J., Saul, J., Festa, F., Wallstrom, G., Yu, X., Bian, X., Anderson, K., Figueroa, J. D., LaBaer, J. & Qiu, J., Jun 2013, In : Proteomics - Clinical Applications. 7, 5-6, p. 378-383 6 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Microarrays
Antibodies
Proteins
HeLa Cells
303 Citations (Scopus)

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

Kang, D. W., Park, J., Ilhan, Z. E., Wallstrom, G., LaBaer, J., Adams, J. & Krajmalnik-Brown, R., Jul 3 2013, In : PLoS One. 8, 7, e68322.

Research output: Contribution to journalArticle

Prevotella
Fermenters
fermenters
Nutrition
Autistic Disorder
2012
21 Citations (Scopus)

High density diffusion-free nanowell arrays

Takulapalli, B. R., Qiu, J., Magee, D., Kahn, P., Brunner, A., Barker, K., Means, S., Miersch, S., Bian, X., Mendoza, A., Festa, F., Syal, K., Park, J., LaBaer, J. & Wiktor, P., Aug 3 2012, In : Journal of Proteome Research. 11, 8, p. 4382-4391 10 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Proteins
Nucleic Acids
Silicon
Proteomics
2011
15 Citations (Scopus)

OpenFreezer: A reagent information management software system

Olhovsky, M., Williton, K., Dai, A. Y., Pasculescu, A., Lee, J. P., Goudreault, M., Wells, C. D., Park, J., Gingras, A. C., Linding, R., Pawson, T. & Colwill, K., Aug 1 2011, In : Nature Methods. 8, 8, p. 612-613 2 p.

Research output: Contribution to journalLetter

Factual Databases
User-Computer Interface
Management Information Systems
Information Storage and Retrieval
Documentation
145 Citations (Scopus)

Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer

Anderson, K., Sibani, S., Wallstrom, G., Mendoza, E. A., Raphael, J., Hainsworth, E., Montor, W. R., Wong, J., Park, J., Lokko, N., Logvinenko, T., Ramachandran, N., Godwin, A. K., Marks, J., Engstrom, P. & LaBaer, J., Jan 7 2011, In : Journal of Proteome Research. 10, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Biomarkers
Microarrays
Early Detection of Cancer
Autoantibodies
36 Citations (Scopus)

PSI: Biology-materials repository: A biologist's resource for protein expression plasmids

Cormier, C. Y., Park, J., Fiacco, M., Steel, J., Hunter, P., Kramer, J., Singla, R. & LaBaer, J., Jul 2011, In : Journal of Structural and Functional Genomics. 12, 2, p. 55-62 8 p.

Research output: Contribution to journalArticle

Plasmids
Proteins
Transfer Agreement
Research Personnel
Pipelines
2009
88 Citations (Scopus)

Eukaryotic protein domains as functional units of cellular evolution

Jin, J., Xie, X., Chen, C., Park, J., Stark, C., James, D. A., Olhovsky, M., Linding, R., Mao, Y. & Pawson, T., Nov 24 2009, In : Science Signaling. 2, 98

Research output: Contribution to journalArticle

Protein Interaction Domains and Motifs
Biological Phenomena
Cellular Microenvironment
Chromatin Assembly and Disassembly
Proteome
107 Citations (Scopus)

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

Chen, C., Jin, J., James, D. A., Adams-Cioaba, M. A., Park, J., Guo, Y., Tenaglia, E., Xu, C., Gish, G., Min, J. & Pawson, T., Dec 1 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 48, p. 20336-20341 6 p.

Research output: Contribution to journalArticle

Arginine
Proteins
Germ Cells
Ligands
Small Interfering RNA
2007
515 Citations (Scopus)

Systematic Discovery of In Vivo Phosphorylation Networks

Linding, R., Jensen, L. J., Ostheimer, G. J., van Vugt, M. A. T. M., Jørgensen, C., Miron, I. M., Diella, F., Colwill, K., Taylor, L., Elder, K., Metalnikov, P., Nguyen, V., Pasculescu, A., Jin, J., Park, J., Samson, L. D., Woodgett, J. R., Russell, RB. B., Bork, P., Yaffe, M. B. & 1 others, Pawson, T., Jun 29 2007, In : Cell. 129, 7, p. 1415-1426 12 p.

Research output: Contribution to journalArticle

Phosphorylation
Phosphotransferases
Substrate Specificity
Substrates
Glycogen Synthase Kinase 3
2004
67 Citations (Scopus)

Analysis of insulin signalling by RNAi-based gene silencing

Zhou, Q. I., Park, J., Jiang, Z. Y., Holik, J. J., Mitra, P., Semiz, S., Guilherme, A., Powelka, A. M., Tang, X., Virbasius, J. & Czech, M. P., Nov 1 2004, In : Biochemical Society Transactions. 32, 5, p. 817-821 5 p.

Research output: Contribution to journalArticle

Gene Silencing
RNA Interference
Genes
RNA
Insulin
2003
115 Citations (Scopus)

Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules

Semiz, S., Park, J., Nicoloro, S. M. C., Furcinitti, P., Zhang, C., Chawla, A., Leszyk, J. & Czech, M. P., May 15 2003, In : EMBO Journal. 22, 10, p. 2387-2399 13 p.

Research output: Contribution to journalArticle

Kinesin
Microtubules
Insulin
Cell membranes
Phosphatidylinositol 3-Kinase
2001
55 Citations (Scopus)

Gα11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane

Bose, A., Cherniack, A. D., Langille, S. E., Nicoloro, S. M. C., Buxton, J. M., Park, J., Chawla, A. & Czech, M. P., Jul 28 2001, In : Molecular and Cellular Biology. 21, 15, p. 5262-5275 14 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Endothelin-1
Actins
Adipocytes
Cell Membrane
25 Citations (Scopus)

PYK2 as a Mediator of Endothelin-1/Gα11 Signaling to GLUT4 Glucose Transporters

Park, J., Bose, A., Leszyk, J. & Czech, M. P., Dec 21 2001, In : Journal of Biological Chemistry. 276, 51, p. 47751-47754 4 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Endothelin-1
Paxillin
Adipocytes
Insulin
29 Citations (Scopus)

Signaling Complexes of the FERM Domain-containing Protein GRSP1 Bound to ARF Exchange Factor GRP1

Klarlund, J. K., Holik, J., Chawla, A., Park, J., Buxton, J. & Czech, M. P., Oct 26 2001, In : Journal of Biological Chemistry. 276, 43, p. 40065-40070 6 p.

Research output: Contribution to journalArticle

Cell membranes
Proteins
Cell Membrane
Brain
Complementary DNA
1999
45 Citations (Scopus)

Transcriptional regulation by the γ5 subunit of a heterotrimeric G protein during adipogenesis

Park, J., Muise, A., He, G. P., Kim, S. W. & Ro, H. S., Jul 15 1999, In : EMBO Journal. 18, 14, p. 4004-4012 9 p.

Research output: Contribution to journalArticle

Heterotrimeric GTP-Binding Proteins
Adipogenesis
Transcription
Carboxypeptidases
Adipocytes