• 493 Citations
  • 10 h-Index
20062021
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Research Output 2006 2019

  • 493 Citations
  • 10 h-Index
  • 23 Article
  • 2 Review article
  • 1 Chapter
2019
1 Citation (Scopus)

Extracellular vesicles as cancer liquid biopsies: From discovery, validation, to clinical application

Zhao, Z., Fan, J., Hsu, Y. M. S., Lyon, C. J., Ning, B. & Hu, Y., Jan 1 2019, In : Lab on a Chip. 19, 7, p. 1114-1140 27 p.

Research output: Contribution to journalReview article

Biopsy
Biomarkers
Tumor Biomarkers
Liquids
Neoplasms

Nanotrap-enabled quantification of KRAS-induced peptide hydroxylation in blood for cancer early detection

Deng, Z., Zhao, Z., Ning, B., Basilio, J., Mann, K., Fu, J., Gu, Y., Ye, Y., Wu, X., Fan, J., Chiao, P. & Hu, Y., Jan 1 2019, In : Nano Research.

Research output: Contribution to journalArticle

Hydroxylation
Bradykinin
Peptides
Blood
Prolyl Hydroxylases
2018

Antigen 85B peptidomic analysis allows species-specific mycobacterial identification

Zhang, W., Shu, Q., Zhao, Z., Fan, J., Lyon, C. J., Zelazny, A. M. & Hu, Y., Jan 8 2018, In : Clinical Proteomics. 15, 1, 1.

Research output: Contribution to journalArticle

Antigens
Peptides
Nontuberculous Mycobacteria
Mycobacterium
Lung
4 Citations (Scopus)

Chemoresistance transmission via exosome-Mediated EphA2 transfer in pancreatic cancer

Fan, J., Wei, Q., Koay, E. J., Liu, Y., Ning, B., Bernard, P. W., Zhang, N., Han, H., Katz, M. H., Zhao, Z. & Hu, Y., Jan 1 2018, In : Theranostics. 8, 21, p. 5986-5994 9 p.

Research output: Contribution to journalArticle

Exosomes
Pancreatic Neoplasms
gemcitabine
Cell Line
Eph Family Receptors
8 Citations (Scopus)

Role of extracellular vesicles in viral and bacterial infections: Pathogenesis, diagnostics, and therapeutics

Rodrigues, M., Fan, J., Lyon, C., Wan, M. & Hu, Y., Jan 1 2018, In : Theranostics. 8, 10, p. 2709-2721 13 p.

Research output: Contribution to journalReview article

Virus Diseases
Bacterial Infections
Exosomes
Therapeutics
Cell Communication
2017
3 Citations (Scopus)

Aptamer internalization via endocytosis inducing s-phase arrest and priming maver-1 lymphoma cells for cytarabine chemotherapy

Li, H., Yang, S., Yu, G., Shen, L., Fan, J., Xu, L., Zhang, H., Zhao, N., Zeng, Z., Hu, Y., Wen, J. & Zu, Y., Jan 1 2017, In : Theranostics. 7, 5, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Cytarabine
Endocytosis
Lymphoma
Drug Therapy
S Phase
2 Citations (Scopus)

Circulating Peptidome and Tumor-Resident Proteolysis

Fan, J., Ning, B., Lyon, C. J. & Hu, Y., Jan 1 2017, Enzymes. Academic Press, p. 1-25 25 p. (Enzymes; vol. 42).

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteolysis
Tumors
Peptide Hydrolases
Neoplasms
Tumor Biomarkers
66 Citations (Scopus)

Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring

Liang, K., Liu, F., Fan, J., Sun, D., Liu, C., Lyon, C. J., Bernard, D. W., Li, Y., Yokoi, K., Katz, M. H., Koay, E. J., Zhao, Z. & Hu, Y., Apr 10 2017, In : Nature Biomedical Engineering. 1, 4, 0021.

Research output: Contribution to journalArticle

Tumors
Assays
Plasmas
Monitoring
Biomarkers
25 Citations (Scopus)

Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring

Liu, C., Zhao, Z., Fan, J., Lyon, C. J., Wu, H. J., Nedelkov, D., Zelazny, A. M., Olivier, K. N., Cazares, L. H., Holland, S. M., Graviss, E. A. & Hu, Y., Apr 11 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 15, p. 3969-3974 6 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Mass Spectrometry
Peptides
Tuberculosis
Sensitivity and Specificity
2 Citations (Scopus)

Rapid diagnosis of new and relapse tuberculosis by quantification of a circulating antigen in HIV-infected adults in the Greater Houston metropolitan area

Fan, J., Zhang, H., Nguyen, D. T., Lyon, C. J., Mitchell, C. D., Zhao, Z., Graviss, E. A. & Hu, Y., Nov 1 2017, In : BMC Medicine. 15, 1, 188.

Research output: Contribution to journalArticle

HIV Antigens
Tuberculosis
Recurrence
Mycobacterium tuberculosis
Serum
2016
9 Citations (Scopus)

Intergenic variable-number tandem-repeat polymorphism upstream of rocA alters toxin production and enhances virulence in Streptococcus pyogenes

Zhu, L., Olsen, R. J., Horstmann, N., Shelburne, S. A., Fan, J., Hu, Y. & Musser, J. M., Jan 1 2016, In : Infection and Immunity. 84, 7, p. 2086-2093 8 p.

Research output: Contribution to journalArticle

Minisatellite Repeats
Streptococcus pyogenes
Virulence
NAD+ Nucleosidase
Necrotizing Fasciitis
1 Citation (Scopus)

Noise reduction method for quantifying nanoparticle light scattering in low magnification dark-field microscope far-field images

Sun, D., Fan, J., Liu, C., Liu, Y., Bu, Y., Lyon, C. J. & Hu, Y., Jan 1 2016, In : Analytical Chemistry. 88, 24, p. 12001-12005 5 p.

Research output: Contribution to journalArticle

Noise abatement
Light scattering
Microscopes
Nanoparticles
Assays
4 Citations (Scopus)

Profiling of cross-functional peptidases regulated circulating peptides in BRCA1 mutant breast cancer

Fan, J., Tea, M. K. M., Yang, C., Ma, L., Meng, Q. H., Hu, Y., Singer, C. F. & Ferrari, M., May 6 2016, In : Journal of Proteome Research. 15, 5, p. 1534-1545 12 p.

Research output: Contribution to journalArticle

Peptide Hydrolases
Breast Neoplasms
Peptides
Tissue Kallikreins
Carboxypeptidase B2
2015
6 Citations (Scopus)

Circulating Peptidome to Indicate the Tumor-resident Proteolysis

Deng, Z., Li, Y., Fan, J., Wang, G., Li, Y., Zhang, Y., Cai, G., Shen, H., Ferrari, M. & Hu, Y., Mar 19 2015, In : Scientific Reports. 5, 9327.

Research output: Contribution to journalArticle

Proteolysis
Metalloproteases
Neoplasms
Peptide Hydrolases
Ovarian Neoplasms
2014
12 Citations (Scopus)

Antibody-free detection of Mycobacterium tuberculosis antigen using customized nanotraps

Wu, H. J., Li, Y., Fan, J., Deng, Z., Hu, Z., Liu, X., Graviss, E. A., Ferrari, M., Ma, X. & Hu, Y., Feb 18 2014, In : Analytical Chemistry. 86, 4, p. 1988-1996 9 p.

Research output: Contribution to journalArticle

Antibodies
Screening
Disease control
Nanopores
Fractionation
11 Citations (Scopus)

Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids

Fan, J., Niu, S., Dong, A., Shi, J., Wu, H. J., Fine, D. H., Tian, Y., Zhou, C., Liu, X., Sun, T., Anderson, G. J., Ferrari, M., Nie, G., Hu, Y. & Zhao, Y., Jan 1 2014, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 5, p. 879-888 10 p.

Research output: Contribution to journalArticle

Nanopores
Hepcidins
Peptides
Fluids
Biomarkers
2013
13 Citations (Scopus)

Serum peptidomic biomarkers for pulmonary metastatic melanoma identified by means of a nanopore-based assay

Fan, J., Huang, Y., Finoulst, I., Wu, H. J., Deng, Z., Xu, R., Xia, X., Ferrari, M., Shen, H. & Hu, Y., Jul 1 2013, In : Cancer Letters. 334, 2, p. 202-210 9 p.

Research output: Contribution to journalArticle

Nanopores
Melanoma
Biomarkers
Lung
Peptides
2012
11 Citations (Scopus)

Low molecular weight protein enrichment on mesoporous silica thin films for biomarker discovery

Fan, J., Gallagher, J. W., Wu, H. J., Landry, M. G., Sakamoto, J., Ferrari, M. & Hu, Y., Apr 17 2012, In : Journal of Visualized Experiments. 62, e3876.

Research output: Contribution to journalArticle

Biomarkers
Proteome
Silicon Dioxide
Molecular Weight
Molecular weight
24 Citations (Scopus)

Research article: Monitoring the progression of metastatic breast cancer on nanoporous silica chips

Fan, J., Deng, X., Gallagher, J. W., Huang, H., Huang, Y., Wen, J., Ferrari, M., Shen, H. & Hu, Y., May 28 2012, In : Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 370, 1967, p. 2433-2447 15 p.

Research output: Contribution to journalArticle

Silica
Breast Cancer
Progression
progressions
breast
2011
195 Citations (Scopus)

Direct evidence for catalase and peroxidase activities of ferritin-platinum nanoparticles

Fan, J., Yin, J. J., Ning, B., Wu, X., Hu, Y., Ferrari, M., Anderson, G. J., Wei, J., Zhao, Y. & Nie, G., Feb 1 2011, In : Biomaterials. 32, 6, p. 1611-1618 8 p.

Research output: Contribution to journalArticle

Ferritins
Platinum
Nanoparticles
Catalase
Peroxidase
2009
4 Citations (Scopus)

Antioxidant effect of human selenium-containing single-chain Fv in rat cardiac myocytes

Huo, R., Shi, Y., Xu, J. J., Yan, F., Lü, S. W., Su, J. M., Duan, Y. J., Fan, J., Ning, B., Cong, D. L., Yan, G. L., Luo, G. M. & Wei, J. Y., Dec 1 2009, In : Chemical Research in Chinese Universities. 25, 2, p. 216-219 4 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Selenium
Rats
Antioxidants
Cells
3 Citations (Scopus)

Dot immunofiltration assay for quantitative detecting cTnI using quantum dots

Fan, J., Song, J., Bi, L. R., Zhou, G. Y., Zhang, H., Wei, J. Y. & Yang, B., Nov 1 2009, In : Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities. 30, 11, p. 2180-2183 4 p.

Research output: Contribution to journalArticle

Troponin I
Semiconductor quantum dots
Assays
Fluorescence
Antibodies
8 Citations (Scopus)

Sandwich immunosensing method for measuring cardiac troponin I with quantum dots-coupled antibody against troponin I

Song, J., Fan, J., Song, D. Q., Bi, L. R., Zhou, G. Y., Zhang, H., Wei, J. Y. & Yang, B., Oct 1 2009, In : Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities. 30, 10, p. 1940-1944 5 p.

Research output: Contribution to journalArticle

Troponin I
Semiconductor quantum dots
Antibodies
Biosensors
Surface plasmon resonance
2008
16 Citations (Scopus)

Human catalytic antibody Se-scFv-B3 with high glutathione peroxidase activity

Huo, R., Wei, J., Xu, J., Lv, S., Zheng, Q., Yan, F., Su, J., Fan, J., Li, J., Duan, Y., Yu, Y., Jin, F., Sun, W., Shi, Y., Cong, D., Li, W., Yan, G. & Luo, G., Sep 1 2008, In : Journal of Molecular Recognition. 21, 5, p. 323-328 6 p.

Research output: Contribution to journalArticle

Catalytic Antibodies
Immunoglobulin Variable Region
Single-Chain Antibodies
Glutathione Peroxidase
Clone Cells
2007
2 Citations (Scopus)

Spleen lymphocyte proteome analysis in bronchial asthma of wistar rats

Li, S. Y., Fan, J., Xi, J. H., Zhang, H. Y., Du, H. W., Zhou, X., Wang, X., Ning, B., Liu, L. Y. & Hao, D. Y., Sep 1 2007, In : Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities. 28, 9, p. 1696-1700 5 p.

Research output: Contribution to journalArticle

Lymphocytes
Proteome
Rats
coenzyme Q10
Proteins
2006
63 Citations (Scopus)

Polyethylene glycol fractionation improved detection of low-abundant proteins by two-dimensional electrophoresis analysis of plant proteome

Xi, J., Wang, X., Li, S., Zhou, X., Yue, L., Fan, J. & Hao, D., Nov 1 2006, In : Phytochemistry. 67, 21, p. 2341-2348 8 p.

Research output: Contribution to journalArticle

Proteome
Fractionation
proteome
polyethylene glycol
Electrophoresis