Jeffrey Langland

Assistant Research Professor

  • 2174 Citations
  • 22 h-Index
1992 …2018
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Research Output 1992 2018

  • 2174 Citations
  • 22 h-Index
  • 51 Article
  • 1 Chapter
2018
3 Citations (Scopus)
Ebolavirus
Herpes Simplex
Vaccinia virus
Antiviral Agents
Metals
1 Citation (Scopus)

Dextrose prolotherapy for chronic shoulder pain: A case report

Seenauth, C., Inouye, V. & Langland, J., Jan 1 2018, In : Alternative Therapies in Health and Medicine. 24, 1, p. 56-60 5 p.

Research output: Contribution to journalArticle

Shoulder Pain
Chronic Pain
Glucose
Pain
Naturopathy

Identification of botanicals with potential therapeutic use against methicillin-resistant Staphylococcus aureus (MRSA) infections

Gerstel, J., Turner, T., Ruiz, G., Wise, J., Stein, A., Jones, G., Morin, T., Pinazza, T., Sukhorukov, E., Clark, D., Steen, T., Wright, B. & Langland, J., Jan 1 2018, (Accepted/In press) In : Phytotherapy Research.

Research output: Contribution to journalArticle

Therapeutic Uses
Methicillin-Resistant Staphylococcus aureus
Methicillin Resistance
Growth
Infection
Dysbiosis
Sodium Acetate
Fixatives
Feces
Acetic Acid

Remission of Schizoaffective Disorder Using Homeopathic Medicine: 2 Case Reports

Grise, D. E., Peyman, T. & Langland, J., Mar 1 2018, In : Alternative Therapies in Health and Medicine. 24, 2, p. 50-56 7 p.

Research output: Contribution to journalArticle

Psychotic Disorders
Therapeutics
Homeopathy
Aptitude
Case Management

The treatment of meniere's disease with acupuncture and Chinese medicine: A case study

Salisbury, L., Deng, Y., Hilmi, Y. & Langland, J., Jun 1 2018, In : Journal of Chinese Medicine. 117, p. 68-71 4 p.

Research output: Contribution to journalArticle

Meniere Disease
Acupuncture
Medicine
Vertigo
Meclizine
1 Citation (Scopus)

The use of intravenous glutathione for symptom management of Parkinson’s disease: A case report

Otto, M., Magerus, T. & Langland, J., Jul 1 2018, In : Alternative Therapies in Health and Medicine. 24, 4, p. 56-60 5 p.

Research output: Contribution to journalArticle

Glutathione
Parkinson Disease
Tremor
Therapeutics
Quality of Life
2017
3 Citations (Scopus)

Characterization of a PKR inhibitor from the pathogenic ranavirus, Ambystoma tigrinum virus, using a heterologous vaccinia virus system

Huynh, T. P., Jancovich, J. K., Tripuraneni, L., Heck, M. C., Langland, J. & Jacobs, B., Nov 1 2017, In : Virology. 511, p. 290-299 10 p.

Research output: Contribution to journalArticle

Ranavirus
Ambystoma
Vaccinia virus
Viruses
Iridoviridae

Enhanced recovery from Bell's palsy with acupuncture and Chinese Herbal Medicine: A case report

Cooper, J., Deng, Y. & Langland, J., Jun 1 2017, In : Journal of Chinese Medicine. 114, p. 48-52 5 p.

Research output: Contribution to journalArticle

Bell Palsy
Herbal Medicine
Acupuncture
Acupuncture Therapy
Aptitude

Enhanced recovery from Bell's Palsy with acupuncture and Chinese herbal medicine: A case report

Cooper, J., Deng, Y. & Langland, J., Jun 1 2017, In : Journal of Chinese Medicine. 2017-June, 114, p. 56-60 5 p.

Research output: Contribution to journalArticle

Bell Palsy
Herbal Medicine
Acupuncture
Acupuncture Therapy
Aptitude
22 Citations (Scopus)

Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

Koehler, H., Cotsmire, S., Langland, J., Kibler, K., Kalman, D., Upton, J. W., Mocarski, E. S. & Jacobs, B., Oct 24 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 43, p. 11506-11511 6 p.

Research output: Contribution to journalArticle

Z-Form DNA
Immune Evasion
Vaccinia virus
Virulence
Cell Death
1 Citation (Scopus)
Chronic Pain
Abdominal Pain
Bacteria
Monosaccharides
Disaccharides

Treatment of athlete’s plantar warts using a botanical blend: A case report

Nelson, E. O., Kozin, A. F., Ruiz Guillermo, G., Lasku, A. & Langland, J., May 1 2017, In : Alternative Therapies in Health and Medicine. 23, 3, p. 51-54 4 p.

Research output: Contribution to journalArticle

Warts
Athletes
Gels
Papillomaviridae
Naturopathy
2016
4 Citations (Scopus)

A lack of bioactive predictability for marker compounds commonly used for herbal medicine standardization

Ruiz, G. G., Nelson, E. O., Kozin, A. F., Turner, T. C., Waters, R. F. & Langland, J., Jul 1 2016, In : PLoS One. 11, 7, e0159857.

Research output: Contribution to journalArticle

Herbal Medicine
herbal medicines
Bioactivity
standardization
Standardization
4 Citations (Scopus)

Characterization of the physiological response following in vivo administration of astragalus membranaceus

Denzler, K., Moore, J., Harrington, H., Morrill, K., Huynh, T., Jacobs, B., Waters, R. & Langland, J., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 6861078.

Research output: Contribution to journalArticle

Astragalus membranaceus
Blood Pressure
Body Temperature
Cytokines
Interleukin-13
8 Citations (Scopus)

Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus

Arndt, W. D., White, S. D., Johnson, B. P., Huynh, T., Liao, J., Harrington, H., Cotsmire, S., Kibler, K., Langland, J. & Jacobs, B., Oct 1 2016, In : Virology. 497, p. 125-135 11 p.

Research output: Contribution to journalArticle

Monkeypox virus
Poxviridae
Vaccinia virus
Virus Diseases
Pharmaceutical Preparations
Bronchial Spasm
Dietary Supplements
Immunoglobulins
Immunoglobulin G
Food
2015
1 Citation (Scopus)
Asthma
Immunoglobulin G
Pharmacology
Diet
Food
2014
14 Citations (Scopus)

A comparison of the anti-staphylococcus aureus activity of extracts from commonly used medicinal plants

Snowden, R., Harrington, H., Morrill, K., Jeane, L. D., Garrity, J., Orian, M., Lopez, E., Rezaie, S., Hassberger, K., Familoni, D., Moore, J., Virdee, K., Albornoz-Sanchez, L., Walker, M., Cavins, J., Russell, T., Guse, E., Reker, M., Tschudy, O., Wolf, J. & 8 others, True, T., Ukaegbu, O., Ahaghotu, E., Jones, A., Polanco, S., Rochon, Y., Waters, R. & Langland, J., May 1 2014, In : Journal of Alternative and Complementary Medicine. 20, 5, p. 375-382 8 p.

Research output: Contribution to journalArticle

Medicinal Plants
Staphylococcus aureus
Turnera
Microbial Sensitivity Tests
Eucalyptus
2013
16 Citations (Scopus)

Spectrum of antimicrobial activity associated with ionic colloidal silver

Morrill, K., May, K., Leek, D., Langland, N., Jeane, L. D., Ventura, J., Skubisz, C., Scherer, S., Lopez, E., Crocker, E., Peters, R., Oertle, J., Nguyen, K., Just, S., Orian, M., Humphrey, M., Payne, D., Jacobs, B., Waters, R. & Langland, J., Mar 1 2013, In : Journal of Alternative and Complementary Medicine. 19, 3, p. 224-231 8 p.

Research output: Contribution to journalArticle

Anti-Infective Agents
Fungi
Growth
Bacteria
Aerobic Bacteria
2012

Fauna of a 400-million-year-old coral reef in Arizona

Langland, J. & Langland, E. V., Jan 31 2012, Rocks and Minerals, 87, 1, p. 40-44 5 p.

Research output: Contribution to specialist publicationArticle

paleotemperature
fossil record
paleoclimate
Gondwana
coral reef
5 Citations (Scopus)

In vitro characterization of a nineteenth-century therapy for smallpox

Arndt, W., Mitnik, C., Denzler, K. L., White, S., Waters, R., Jacobs, B., Rochon, Y., Olson, V. A., Damon, I. K. & Langland, J., Mar 9 2012, In : PLoS One. 7, 3, e32610.

Research output: Contribution to journalArticle

Sarraceniaceae
Smallpox
Poxviridae
Viruses
therapeutics
2011
6 Citations (Scopus)

Use of a negative selectable marker for rapid selection of recombinant vaccinia virus

White, S. D., Conwell, K., Langland, J. & Jacobs, B., May 2011, In : BioTechniques. 50, 5, p. 303-309 7 p.

Research output: Contribution to journalArticle

Vaccinia virus
Viruses
Phosphorylation
Dimerization
Homologous Recombination
29 Citations (Scopus)
Double-Stranded RNA
Vaccinia virus
RNA Viruses
Viral RNA
Viruses
2010
24 Citations (Scopus)

Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals

Denzler, K. L., Waters, R., Jacobs, B., Rochon, Y. & Langland, J., 2010, In : PLoS One. 5, 9, p. 1-15 15 p., e12561.

Research output: Contribution to journalArticle

Gene Expression Regulation
mononuclear leukocytes
Gene expression
herbs
Genes
2009
36 Citations (Scopus)
eIF-2 Kinase
Vaccinia virus
Mitogen-Activated Protein Kinases
mitogen-activated protein kinase
protein kinases
113 Citations (Scopus)

Vaccinia virus vaccines: Past, present and future

Jacobs, B., Langland, J., Kibler, K., Denzler, K. L., White, S. D., Holechek, S. A., Wong, S., Huynh, T. & Baskin, C. R., Oct 2009, In : Antiviral Research. 84, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Vaccinia virus
Vaccines
Smallpox
Viral Genes
Variola virus
2008
31 Citations (Scopus)

Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: Scarification vaccination

Jentarra, G. M., Heck, M. C., Youn, J. W., Kibler, K., Langland, J., Baskin, C. R., Ananieva, O., Chang, Y. & Jacobs, B., Jun 2 2008, In : Vaccine. 26, 23, p. 2860-2872 13 p.

Research output: Contribution to journalArticle

Attenuated Vaccines
Vaccinia virus
live vaccines
Vaccination
vaccination
2007
77 Citations (Scopus)

Mouse hepatitis coronavirus A59 nucleocapsid protein is a type I interferon antagonist

Ye, Y., Hauns, K., Langland, J., Jacobs, B. & Hogue, B., Mar 2007, In : Journal of Virology. 81, 6, p. 2554-2563 10 p.

Research output: Contribution to journalArticle

nucleocapsid proteins
Interferon Type I
Coronavirinae
hepatitis
Murine hepatitis virus
2006
156 Citations (Scopus)

Inhibition of PKR by RNA and DNA viruses

Langland, J., Cameron, J. M., Heck, M. C., Jancovich, J. K. & Jacobs, B., Jul 2006, In : Virus Research. 119, 1, p. 100-110 11 p.

Research output: Contribution to journalArticle

DNA Viruses
RNA Viruses
Interferons
Innate Immunity
eIF-2 Kinase
57 Citations (Scopus)

Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins

Langland, J., Kash, J. C., Carter, V., Thomas, M. J., Katze, M. G. & Jacobs, B., Oct 2006, In : Journal of Virology. 80, 20, p. 10083-10095 13 p.

Research output: Contribution to journalArticle

Vaccinia virus
Double-Stranded RNA
Z-Form DNA
Nucleic Acids
nucleic acids
2005

Viral Countermeasures to the Host Interferon Response: Role of the Vaccinia Virus E3L and K3L Genes

Langland, J., Lancaster, V. & Jacobs, B., Jan 27 2005, Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats. John Wiley and Sons, p. 353-376 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Z-Form DNA
Double-Stranded RNA
Viruses
Interferons
Genes
2004
72 Citations (Scopus)

Inhibition of PKR by vaccinia virus: Role of the N- and C-terminal domains of E3L

Langland, J. & Jacobs, B., Jul 1 2004, In : Virology. 324, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Vaccinia virus
Phosphorylation
Antiviral Agents
Peptide Initiation Factors
Double-Stranded RNA
2003
3 Citations (Scopus)
Nuclear Factor 90 Proteins
Vaccinia virus
Interleukin-2
Gene Expression
Double-Stranded RNA
18 Citations (Scopus)

The Orf virus E3L homologue is able to complement deletion of the vaccinia virus E3L gene in vitro but not in vivo

Vijaysri, S., Talasela, L., Mercer, A. A., Mcinnes, C. J., Jacobs, B. & Langland, J., Sep 15 2003, In : Virology. 314, 1, p. 305-314 10 p.

Research output: Contribution to journalArticle

Orf virus
Vaccinia virus
Genes
Open Reading Frames
Lethal Dose 50
2002
120 Citations (Scopus)

The role of the PKR-inhibitory genes, E3L and K3L, in determining vaccinia virus host range

Langland, J. & Jacobs, B., 2002, In : Virology. 299, 1, p. 133-141 9 p.

Research output: Contribution to journalArticle

Vaccinia virus
Host Specificity
Double-Stranded RNA
eIF-2 Kinase
Genes
2001
50 Citations (Scopus)

Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A

He, Y., Tan, S. L., Tareen, S. U., Vijaysri, S., Langland, J., Jacobs, B. & Katze, M. G., 2001, In : Journal of Virology. 75, 11, p. 5090-5098 9 p.

Research output: Contribution to journalArticle

cell communication
Hepatitis C virus
Protein Biosynthesis
Hepacivirus
protein kinases
1999
92 Citations (Scopus)
Nuclear Factor 90 Proteins
eIF-2 Kinase
NFATC Transcription Factors
RNA-Binding Proteins
T-cells
1998
41 Citations (Scopus)

Activation of antiviral protein kinase leads to immunoglobulin E class switching in human B cells

Rager, K. J., Langland, J., Jacobs, B., Proud, D., Marsh, D. G. & Imani, F., Feb 1998, In : Journal of Virology. 72, 2, p. 1171-1176 6 p.

Research output: Contribution to journalArticle

antiviral proteins
Immunoglobulin Class Switching
immunoglobulin E
protein kinases
Protein Kinases
14 Citations (Scopus)

Characterization of viral double-stranded RNA-binding proteins

Jacobs, B., Langland, J. & Brandt, T., 1998, In : Methods: A Companion to Methods in Enzymology. 15, 3, p. 225-232 8 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Viral RNA
Viral Proteins
Viruses
Virus Activation
6 Citations (Scopus)

Differential localization and accumulation of the plant double stranded RNA-dependent protein kinase during virus infection

Langland, J., Langland, L. & Roth, D., Jan 1 1998, In : Plant Physiology and Biochemistry. 36, 5, p. 395-400 6 p.

Research output: Contribution to journalArticle

Plant RNA
eIF-2 Kinase
Double-Stranded RNA
double-stranded RNA
Virus Diseases
29 Citations (Scopus)
Orthoreovirus
Reoviridae
eIF-2 Kinase
RNA-Binding Proteins
Double-Stranded RNA
1997
14 Citations (Scopus)

Developmental regulation of a plant encoded inhibitor of eukaryotic initiation factor 2α phosphorylation

Langland, J., Langland, L., Zeman, C., Saha, D. & Roth, D. A., Aug 1 1997, In : Plant Journal. 12, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-2
phosphorylation
Phosphorylation
reticulocytes
double-stranded RNA
165 Citations (Scopus)

Double-stranded RNA is a trigger for apoptosis in vaccinia virus- infected cells

Kibler, K., Shors, T., Perkins, K. B., Zeman, C. C., Banaszak, M. P., Biesterfeldt, J., Langland, J. & Jacobs, B., Mar 1997, In : Journal of Virology. 71, 3, p. 1992-2003 12 p.

Research output: Contribution to journalArticle

Vaccinia virus
Double-Stranded RNA
double-stranded RNA
apoptosis
Apoptosis
1996
49 Citations (Scopus)
Eukaryotic Initiation Factor-2
eIF-2 Kinase
Phosphorylation
Double-Stranded RNA
Phosphotransferases
3 Citations (Scopus)

Polyanion regulation of the plant-encoded double-stranded RNA- dependent protein kinase (pPKR)

Langland, J., Langland, L. A. & Roth, D. A., Jan 1 1996, In : Plant Physiology and Biochemistry. 34, 4, p. 521-526 6 p.

Research output: Contribution to journalArticle

eIF-2 Kinase
Double-Stranded RNA
double-stranded RNA
protein kinases
Phosphorylation
488 Citations (Scopus)

When Two Strands Are Better Than One: The Mediators and Modulators of the Cellular Responses to Double-Stranded RNA

Jacobs, B. & Langland, J., May 15 1996, In : Virology. 219, 2, p. 339-349 11 p.

Research output: Contribution to journalArticle

Double-Stranded RNA
Interferon Inducers
Virus Diseases
Interferons
Antiviral Agents
1995
50 Citations (Scopus)

Identification of a plant-encoded analog of PKR, the mammalian double-stranded RNA-dependent protein kinase

Langland, J., Jin, S., Jacobs, B. & Roth, D. A., Jul 1995, In : Plant Physiology. 108, 3, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

eIF-2 Kinase
Double-Stranded RNA
double-stranded RNA
protein kinases
antiserum
27 Citations (Scopus)

Nucleic Acid Affinity Chromatography: Preparation and Characterization of Double-Stranded RNA Agarose

Langland, J., Pettiford, S. M. & Jacobs, B., Feb 1995, In : Protein Expression and Purification. 6, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Affinity chromatography
Double-Stranded RNA
Affinity Chromatography
Sepharose
Nucleic Acids
1994
73 Citations (Scopus)
Rotavirus C
eIF-2 Kinase
RNA-Binding Proteins
Double-Stranded RNA
Rotavirus