Haiwei Gu

Asst Professor

  • 2646 Citations
  • 29 h-Index
20072023

Research output per year

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Research Output

  • 2646 Citations
  • 29 h-Index
  • 90 Article
  • 4 Review article
  • 2 Comment/debate
  • 1 Chapter
Article

Mass spectral similarity networking and gas-phase fragmentation reactions in the structural analysis of flavonoid glycoconjugates

Pilon, A. C., Gu, H., Raftery, D., Bolzani, V. D. S., Lopes, N. P., Castro-Gamboa, I. & Carnevale Neto, F., Aug 20 2019, In : Analytical chemistry. 91, 16, p. 10458-10466 9 p.

Research output: Contribution to journalArticle

Open Access

Mass Spectral Similarity Networking and Gas-Phase Fragmentation Reactions in the Structural Analysis of Flavonoid Glycoconjugates

Pilon, A. C., Gu, H., Raftery, D., Bolzani, V. D. S., Lopes, N. P., Castro-Gamboa, I. & Carnevale Neto, F., Jan 1 2018, (Accepted/In press) In : Analytical chemistry.

Research output: Contribution to journalArticle

2 Scopus citations

Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry

Lu, H., Zhang, H., Zhu, T., Xiao, Y., Xie, S., Gu, H., Cui, M. & Luo, L., Dec 1 2017, In : Scientific Reports. 7, 1, 5136.

Research output: Contribution to journalArticle

8 Scopus citations

Metabolic profiling identifies phospholipids as potential serum biomarkers for schizophrenia

Wang, D., Cheng, S. L., Fei, Q., Gu, H., Raftery, D., Cao, B., Sun, X., Yan, J., Zhang, C. & Wang, J., Feb 1 2019, In : Psychiatry Research. 272, p. 18-29 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Metabolomics method to comprehensively analyze amino acids in different domains

Gu, H., Du, J., Carnevale Neto, F., Carroll, P. A., Turner, S. J., Chiorean, E. G., Eisenman, R. N. & Raftery, D., Apr 21 2015, In : Analyst. 140, 8, p. 2726-2734 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
14 Scopus citations

Metabolomics test materials for quality control: A study of a urine materials suite

Bearden, D. W., Sheen, D. A., Simón-Manso, Y., Benner, B. A., Rocha, W. F. C., Blonder, N., Lippa, K. A., Beger, R. D., Schnackenberg, L. K., Sun, J., Mehta, K. Y., Cheema, A. K., Gu, H., Marupaka, R., Nagana Gowda, G. A. & Raftery, D., Nov 2019, In : Metabolites. 9, 11, 270.

Research output: Contribution to journalArticle

Open Access

Monitoring diet effects via biofluids and their implications for metabolomics studies

Gu, H., Chen, H., Pan, Z., Jackson, A. U., Talaty, N., Xi, B., Kissinger, C., Duda, C., Mann, D., Raftery, D. & Cooks, R. G., Jan 1 2007, In : Analytical chemistry. 79, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Multiplatform Metabolomics Investigation of Antiadipogenic Effects on 3T3-L1 Adipocytes by a Potent Diarylheptanoid

Du, D., Gu, H., Djukovic, D., Bettcher, L., Gong, M., Zheng, W., Hu, L., Zhang, X., Zhang, R., Wang, D. & Raftery, D., Jun 1 2018, In : Journal of Proteome Research. 17, 6, p. 2092-2101 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

NMR-Guided Mass Spectrometry for Absolute Quantitation of Human Blood Metabolites

Nagana Gowda, G. A., Djukovic, D., Bettcher, L. F., Gu, H. & Raftery, D., Feb 6 2018, In : Analytical Chemistry. 90, 3, p. 2001-2009 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

Davis, R. J., Gönen, M., Margineantu, D. H., Handeli, S., Swanger, J., Hoellerbauer, P., Paddison, P. J., Gu, H., Raftery, D., Grim, J. E., Hockenbery, D. M., Margolin, A. A. & Clurman, B. E., May 22 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 21, p. 5462-5467 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Parenteral and enteral nutrition in surgical critical care: Plasma metabolomics demonstrates divergent effects on nitrogen, fatty-acid, ribonucleotide, and oxidative metabolism

Parent, B. A., Seaton, M., Djukovic, D., Gu, H., Wheelock, B., Navarro, S. L., Raftery, D. & O'Keefe, G. E., Apr 1 2017, In : Journal of Trauma and Acute Care Surgery. 82, 4, p. 704-713 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

PBDEs altered gut microbiome and bile acid homeostasis in male C57BL/6 mice

Li, C. Y., Dempsey, J. L., Wang, D., Lee, S. W., Weigel, K. M., Fei, Q., Bhatt, D. K., Prasad, B., Raftery, D., Gu, H. & Cui, J. Y., Aug 1 2018, In : Drug Metabolism and Disposition. 46, 8, p. 1226-1240 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Peak capacity optimization in comprehensive two dimensional liquid chromatography: A practical approach

Gu, H., Huang, Y. & Carr, P. W., Jan 7 2011, In : Journal of Chromatography A. 1218, 1, p. 64-73 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Pharmacological Activation of PXR and CAR Downregulates Distinct Bile Acid-Metabolizing Intestinal Bacteria and Alters Bile Acid Homeostasis

Dempsey, J. L., Wang, D., Siginir, G., Fei, Q., Raftery, D., Gu, H. & Yue Cui, J., Mar 1 2019, In : Toxicological Sciences. 168, 1, p. 40-60 21 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina

Du, J., Rountree, A., Cleghorn, W. M., Contreras, L., Lindsay, K. J., Sadilek, M., Gu, H., Djukovic, D., Raftery, D., Satrústegui, J., Kanow, M., Chan, L., Tsang, S. H., Sweet, I. R. & Hurley, J. B., Feb 26 2016, In : Journal of Biological Chemistry. 291, 9, p. 4698-4710 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets

Miles, F. L., Navarro, S. L., Schwarz, Y., Gu, H., Djukovic, D., Randolph, T. W., Shojaie, A., Kratz, M., Hullar, M. A. J., Lampe, P. D., Neuhouser, M. L., Raftery, D. & Lampe, J. W., Sep 1 2017, In : Food and Function. 8, 9, p. 3209-3218 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Plasma metabolomics profiles suggest beneficial effects of a low-glycemic load dietary pattern on inflammation and energy metabolism

Navarro, S. L., Tarkhan, A., Shojaie, A., Randolph, T. W., Gu, H., Djukovic, D., Osterbauer, K. J., Hullar, M. A., Kratz, M., Neuhouser, M. L., Lampe, P. D., Raftery, D. & Lampe, J. W., Oct 1 2019, In : American Journal of Clinical Nutrition. 110, 4, p. 984-992 9 p.

Research output: Contribution to journalArticle

Polybrominated diphenyl ethers and gut microbiome modulate metabolic syndrome-related aqueous metabolites in mice

Scoville, D. K., Li, C. Y., Wang, D., Dempsey, J. L., Raftery, D., Mani, S., Gu, H. & Cui, J. Y., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 8, p. 928-940 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism

Pan, Z., Gu, H., Talaty, N., Chen, H., Shanaiah, N., Hainline, B. E., Cooks, R. G. & Raftery, D., Jan 1 2007, In : Analytical and bioanalytical chemistry. 387, 2, p. 539-549 11 p.

Research output: Contribution to journalArticle

122 Scopus citations

Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer

Gu, H., Pan, Z., Xi, B., Asiago, V., Musselman, B. & Raftery, D., Feb 7 2011, In : Analytica Chimica Acta. 686, 1-2, p. 57-63 7 p.

Research output: Contribution to journalArticle

99 Scopus citations

Quantitative detection of nitric oxide in exhaled human breath by extractive electrospray ionization mass spectrometry

Pan, S., Tian, Y., Li, M., Zhao, J., Zhu, L., Zhang, W., Gu, H., Wang, H., Shi, J., Fang, X., Li, P. & Chen, H., Jan 1 2015, In : Scientific Reports. 5, 8725.

Research output: Contribution to journalArticle

19 Scopus citations

Quantitative Method to Investigate the Balance between Metabolism and Proteome Biomass: Starting from Glycine

Gu, H., Carroll, P. A., Du, J., Zhu, J., Neto, F. C., Eisenman, R. N. & Raftery, D., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 50, p. 15646-15650 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

RAMSY: Ratio analysis of mass spectrometry to improve compound identification

Gu, H., Gowda, G. A. N., Neto, F. C., Opp, M. R. & Raftery, D., Nov 19 2013, In : Analytical chemistry. 85, 22, p. 10771-10779 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment

Quarles, E., Basisty, N., Chiao, Y. A., Merrihew, G., Gu, H., Sweetwyne, M. T., Fredrickson, J., Nguyen, N. H., Razumova, M., Kooiker, K., Moussavi-Harami, F., Regnier, M., Quarles, C., MacCoss, M. & Rabinovitch, P. S., Jan 1 2019, (Accepted/In press) In : Aging Cell. e13086.

Research output: Contribution to journalArticle

Open Access

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

Chiao, Y. A., Kolwicz, S. C., Basisty, N., Gagnidze, A., Zhang, J., Gu, H., Djukovic, D., Beyer, R. P., Raftery, D., MacCoss, M., Tian, R. & Rabinovitch, P. S., Jan 1 2016, In : Aging. 8, 2, p. 314-327 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

Rapid analysis of aerosol drugs using nano extractive electrospray ionization tandem mass spectrometry

Gu, H., Hu, B., Li, J., Yang, S., Han, J. & Chen, H., Jun 1 2010, In : Analyst. 135, 6, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Salivary metabolite profiling distinguishes patients with oral cavity squamous cell carcinoma from normal controls

Lohavanichbutr, P., Zhang, Y., Wang, P., Gu, H., Nagana Gowda, G. A., Djukovic, D., Buas, M. F., Raftery, D. & Chen, C., Sep 1 2018, In : PLoS One. 13, 9, e0204249.

Research output: Contribution to journalArticle

8 Scopus citations

Selective detection of diethylene glycol in toothpaste products using neutral desorption reactive extractive electrospray ionization tandem mass spectrometry

Ding, J., Gu, H., Yang, S., Li, M., Li, J. & Chen, H., Oct 15 2009, In : Analytical chemistry. 81, 20, p. 8632-8638 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Sensitive ionization of non-volatile analytes using protein solutions as spray liquid in desorption electrospray ionization mass spectrometry

Zhu, Z., Han, J., Zhang, Y., Zhou, Y., Xu, N., Zhang, B., Gu, H. & Chen, H., Dec 15 2012, In : Rapid Communications in Mass Spectrometry. 26, 23, p. 2770-2776 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)

Heitkemper, M. M., Han, C. J., Jarrett, M. E., Gu, H., Djukovic, D., Shulman, R. J., Raftery, D., Henderson, W. A. & Cain, K. C., Mar 1 2016, In : Biological Research for Nursing. 18, 2, p. 193-198 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Statistical analysis and modeling of mass spectrometry-based metabolomics data

Xi, B., Gu, H., Baniasadi, H. & Raftery, D., Jan 1 2014, In : Methods in Molecular Biology. 1198, p. 333-353 21 p.

Research output: Contribution to journalArticle

54 Scopus citations

Targeted metabolic profiling of hepatocellular carcinoma and hepatitis C using LC-MS/MS

Baniasadi, H., Gowda, G. A. N., Gu, H., Zeng, A., Zhuang, S., Skill, N., Maluccio, M. & Raftery, D., Oct 1 2013, In : Electrophoresis. 34, 19, p. 2910-2917 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Targeted metabolic profiling of wounds in diabetic and nondiabetic mice

Sood, R. F., Gu, H., Djukovic, D., Deng, L., Ga, M., Muffley, L. A., Raftery, D. & Hocking, A. M., Jan 1 2015, In : Wound Repair and Regeneration. 23, 3, p. 423-434 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Targeted plasma metabolome response to variations in dietary glycemic load in a randomized, controlled, crossover feeding trial in healthy adults

Barton, S., Navarro, S. L., Buas, M. F., Schwarz, Y., Gu, H., Djukovic, D., Raftery, D., Kratz, M., Neuhouser, M. L. & Lampe, J. W., Jan 1 2015, In : Food and Function. 6, 9, p. 2949-2956 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Targeted serum metabolite profiling and sequential metabolite ratio analysis for colorectal cancer progression monitoring

Zhu, J., Djukovic, D., Deng, L., Gu, H., Himmati, F., Abu Zaid, M., Chiorean, E. G. A. & Raftery, D., Oct 1 2015, In : Analytical and Bioanalytical Chemistry. 407, 26, p. 7857-7863 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

Sperber, H., Mathieu, J., Wang, Y., Ferreccio, A., Hesson, J., Xu, Z., Fischer, K. A., Devi, A., Detraux, D., Gu, H., Battle, S. L., Showalter, M., Valensisi, C., Bielas, J. H., Ericson, N. G., Margaretha, L., Robitaille, A. M., Margineantu, D., Fiehn, O., Hockenbery, D. & 7 others, Blau, C. A., Raftery, D., Margolin, A. A., Hawkins, R. D., Moon, R. T., Ware, C. B. & Ruohola-Baker, H., Nov 27 2015, In : Nature Cell Biology. 17, 12, p. 1523-1535 13 p.

Research output: Contribution to journalArticle

148 Scopus citations

Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer

Li, R., Grimm, S. A., Mav, D., Gu, H., Djukovic, D., Shah, R., Merrick, B. A., Raftery, D. & Wade, P. A., Jan 16 2018, In : Cell Reports. 22, 3, p. 624-637 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish

Rabinowitz, J. S., Robitaille, A. M., Wang, Y., Ray, C. A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J. D. & Moon, R. T., Jan 31 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. E717-E726

Research output: Contribution to journalArticle

29 Scopus citations

Use of metabolomics to trend recovery and therapy after injury in critically ill trauma patients

Parent, B. A., Seaton, M., Sood, R. F., Gu, H., Djukovic, D., Raftery, D. & O'Keefe, G. E., Jul 1 2016, In : JAMA Surgery. 151, 7

Research output: Contribution to journalArticle

12 Scopus citations
Chapter

Rapid and sensitive detection of chemical explosives using ambient mass spectrometry

Chen, H. & Gu, H., Feb 1 2011, Explosive Materials: Classification, Composition and Properties. Nova Science Publishers, Inc., p. 81-101 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Correction to Mass Spectral Similarity Networking and Gas-Phase Fragmentation Reactions in the Structural Analysis of Flavonoid Glycoconjugates (Anal. Chem. (2019) 91:16 (10413-10423) DOI: 10.1021/acs.analchem.8b05479)

Pilon, A. C., Gu, H., Raftery, D., Da Silva Bolzani, V., Lopes, N. P., Castro-Gamboa, I. & Carnevale Neto, F., Jan 1 2019, (Accepted/In press) In : Analytical chemistry.

Research output: Contribution to journalComment/debate

Open Access
Review article

Direct analysis of biological samples using extractive electrospray ionization mass spectrometry (EESI-MS)

Gu, H., Xu, N. & Chen, H., Jun 1 2012, In : Analytical and bioanalytical chemistry. 403, 8, p. 2145-2153 9 p.

Research output: Contribution to journalReview article

29 Scopus citations

Metabolic profiling: Are we en route to better diagnostic tests for cancer?

Gu, H., Gowda, G. A. N. & Raftery, D., Oct 1 2012, In : Future Oncology. 8, 10, p. 1207-1210 4 p.

Research output: Contribution to journalReview article

22 Scopus citations

Metabolomics-based methods for early disease diagnostics

Gowda, G. A. N., Zhang, S., Gu, H., Asiago, V., Shanaiah, N. & Raftery, D., Sep 1 2008, In : Expert Review of Molecular Diagnostics. 8, 5, p. 617-633 17 p.

Research output: Contribution to journalReview article

351 Scopus citations

Nuclear magnetic resonance spectroscopy and mass spectrometry-based metabolomics for cancer diagnosis

Gu, H. W., Qi, Y. P., Xu, N., Ding, J. H., An, Y. B. & Chen, H. W., Dec 2012, In : Fenxi Huaxue/ Chinese Journal of Analytical Chemistry. 40, 12, p. 1933-1937 5 p.

Research output: Contribution to journalReview article

3 Scopus citations