• 2363 Citations
  • 27 h-Index
20072023
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Research Output 2007 2019

  • 2363 Citations
  • 27 h-Index
  • 79 Article
  • 4 Review article
  • 1 Chapter
  • 1 Comment/debate
2014
85 Citations (Scopus)

Colorectal cancer detection using targeted serum metabolic profiling

Zhu, J., Djukovic, D., Deng, L., Gu, H., Himmati, F., Chiorean, E. G. & Raftery, D., Jan 1 2014, In : Journal of Proteome Research. 13, 9, p. 4120-4130 11 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Biomarkers
Discriminant analysis
Serum
Polyps
1 Citation (Scopus)

Development of adjustable device for extractive electrospray ionization with improved performance

Dong, X. F., Liu, L., Wang, J., Xu, N., Gu, H., Zhou, S. M. & Chen, H. W., Jan 1 2014, In : Journal of Chinese Mass Spectrometry Society. 35, 3, p. 226-231 6 p.

Research output: Contribution to journalArticle

ionization
mass spectroscopy
glutamine
aspartic acid
phenylalanine
7 Citations (Scopus)

Global metabolic profiling using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Qi, Y., Song, Y., Gu, H., Fan, G. & Chai, Y., Jan 1 2014, In : Methods in Molecular Biology. 1198, p. 15-27 13 p.

Research output: Contribution to journalArticle

Liquid Chromatography
Mass Spectrometry
Metabolomics
Tandem Mass Spectrometry
Acetone
29 Citations (Scopus)

Integrated plasma and urine metabolomics coupled with HPLC/QTOF-MS and chemometric analysis on potential biomarkers in liver injury and hepatoprotective effects of Er-Zhi-Wan

Yao, W., Gu, H., Zhu, J., Barding, G., Cheng, H., Bao, B., Zhang, L., Ding, A. & Li, W., Oct 23 2014, In : Analytical and Bioanalytical Chemistry. 406, 28, p. 7367-7378 12 p.

Research output: Contribution to journalArticle

Metabolomics
Biomarkers
Metabolites
Liver
High Pressure Liquid Chromatography
44 Citations (Scopus)

Statistical analysis and modeling of mass spectrometry-based metabolomics data

Xi, B., Gu, H., Baniasadi, H. & Raftery, D., Jan 1 2014, In : Methods in Molecular Biology. 1198, p. 333-353 21 p.

Research output: Contribution to journalArticle

Metabolomics
Principal Component Analysis
Least-Squares Analysis
ROC Curve
Mass Spectrometry
2013
44 Citations (Scopus)

15N-Cholamine - A smart isotope tag for combining NMR- and MS-based metabolite profiling

Tayyari, F., Gowda, G. A. N., Gu, H. & Raftery, D., Sep 17 2013, In : Analytical Chemistry. 85, 18, p. 8715-8721 7 p.

Research output: Contribution to journalArticle

Metabolites
Isotopes
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Metabolomics
35 Citations (Scopus)

Direct characterization of bulk samples by internal extractive electrospray ionization mass spectrometry

Zhang, H., Gu, H., Yan, F., Wang, N., Wei, Y., Xu, J. & Chen, H., Sep 5 2013, In : Scientific Reports. 3, 2495.

Research output: Contribution to journalArticle

Electrospray Ionization Mass Spectrometry
Chewing Gum
Fruit
Lung
14 Citations (Scopus)

Direct detection of amino acids using extractive electrospray ionization tandem mass spectrometry

Xu, N., Zhu, Z. Q., Yang, S. P., Wang, J., Gu, H., Zhou, Z. & Chen, H. W., Jan 1 2013, In : Fenxi Huaxue/ Chinese Journal of Analytical Chemistry. 41, 4, p. 523-528 6 p.

Research output: Contribution to journalArticle

Electrospray ionization
Mass spectrometry
Amino Acids
Ion sources
Methanol
21 Citations (Scopus)

Facilitated diffusion of acetonitrile revealed by quantitative breath analysis using extractive electrospray ionization mass spectrometry

Li, M., Ding, J., Gu, H., Zhang, Y., Pan, S., Xu, N., Chen, H. & Li, H., Feb 18 2013, In : Scientific Reports. 3, 1205.

Research output: Contribution to journalArticle

Facilitated Diffusion
Electrospray Ionization Mass Spectrometry
Silver
Limit of Detection
Cations
14 Citations (Scopus)
Metabolomics
Metabolic Networks and Pathways
Liquid Chromatography
Myocardial Ischemia
Mass Spectrometry
17 Citations (Scopus)

RAMSY: Ratio analysis of mass spectrometry to improve compound identification

Gu, H., Gowda, G. A. N., Neto, F. C., Opp, M. R. & Raftery, D., Nov 19 2013, In : Analytical Chemistry. 85, 22, p. 10771-10779 9 p.

Research output: Contribution to journalArticle

Mass spectrometry
Metabolites
Correlation methods
Liquid chromatography
Gas chromatography
22 Citations (Scopus)

Targeted metabolic profiling of hepatocellular carcinoma and hepatitis C using LC-MS/MS

Baniasadi, H., Gowda, G. A. N., Gu, H., Zeng, A., Zhuang, S., Skill, N., Maluccio, M. & Raftery, D., Oct 1 2013, In : Electrophoresis. 34, 19, p. 2910-2917 8 p.

Research output: Contribution to journalArticle

Hepatitis C
Viruses
Hepatocellular Carcinoma
Hepacivirus
Metabolites
2012
13 Citations (Scopus)

Detection of trace levels of lead in aqueous liquids using extractive electrospray ionization tandem mass spectrometry

Liu, C., Zhang, X., Xiao, S., Jia, B., Cui, S., Shi, J., Xu, N., Xie, X., Gu, H. & Chen, H., Aug 30 2012, In : Talanta. 98, p. 79-85 7 p.

Research output: Contribution to journalArticle

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Tandem Mass Spectrometry
Diamines
Mass spectrometry
27 Citations (Scopus)

Direct analysis of biological samples using extractive electrospray ionization mass spectrometry (EESI-MS)

Gu, H., Xu, N. & Chen, H., Jun 1 2012, In : Analytical and Bioanalytical Chemistry. 403, 8, p. 2145-2153 9 p.

Research output: Contribution to journalReview article

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Mass spectrometry
Mass Spectrometry
Gases
21 Citations (Scopus)

Metabolic profiling: Are we en route to better diagnostic tests for cancer?

Gu, H., Gowda, G. A. N. & Raftery, D., Oct 1 2012, In : Future Oncology. 8, 10, p. 1207-1210 4 p.

Research output: Contribution to journalReview article

Metabolomics
Metabolome
Routine Diagnostic Tests
Biomarkers
Neoplasms
2 Citations (Scopus)

Nuclear magnetic resonance spectroscopy and mass spectrometry-based metabolomics for cancer diagnosis

Gu, H., Qi, Y. P., Xu, N., Ding, J. H., An, Y. B. & Chen, H. W., Jan 1 2012, In : Fenxi Huaxue/ Chinese Journal of Analytical Chemistry. 40, 12, p. 1933-1937 5 p.

Research output: Contribution to journalReview article

Nuclear magnetic resonance spectroscopy
Mass spectrometry
Metabolites
Metabolomics
Blood
3 Citations (Scopus)

Sensitive ionization of non-volatile analytes using protein solutions as spray liquid in desorption electrospray ionization mass spectrometry

Zhu, Z., Han, J., Zhang, Y., Zhou, Y., Xu, N., Zhang, B., Gu, H. & Chen, H., Dec 15 2012, In : Rapid Communications in Mass Spectrometry. 26, 23, p. 2770-2776 7 p.

Research output: Contribution to journalArticle

Electrospray ionization
Ionization
Mass spectrometry
Desorption
Liquids
2011
38 Citations (Scopus)

An experimental study of sampling time effects on the resolving power of on-line two-dimensional high performance liquid chromatography

Huang, Y., Gu, H., Filgueira, M. & Carr, P. W., May 20 2011, In : Journal of Chromatography A. 1218, 20, p. 2984-2994 11 p.

Research output: Contribution to journalArticle

Sampling Studies
Optical resolving power
High performance liquid chromatography
High Pressure Liquid Chromatography
Sampling
10 Citations (Scopus)

Direct detection of native proteins in biological matrices using extractive electrospray ionization mass spectrometry

Hu, B., Yang, S., Li, M., Gu, H. & Chen, H., Sep 21 2011, In : Analyst. 136, 18, p. 3599-3601 3 p.

Research output: Contribution to journalArticle

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Mass spectrometry
ionization
mass spectrometry
17 Citations (Scopus)

Effect of first dimension phase selectivity in online comprehensive two dimensional liquid chromatography (LC×LC)

Gu, H., Huang, Y., Filgueira, M. & Carr, P. W., Sep 23 2011, In : Journal of Chromatography A. 1218, 38, p. 6675-6687 13 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Carbon
Clad metals
Oxides
46 Citations (Scopus)

Peak capacity optimization in comprehensive two dimensional liquid chromatography: A practical approach

Gu, H., Huang, Y. & Carr, P. W., Jan 7 2011, In : Journal of Chromatography A. 1218, 1, p. 64-73 10 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Sampling
Phase composition
Flow rate
93 Citations (Scopus)

Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer

Gu, H., Pan, Z., Xi, B., Asiago, V., Musselman, B. & Raftery, D., Feb 7 2011, In : Analytica Chimica Acta. 686, 1-2, p. 57-63 7 p.

Research output: Contribution to journalArticle

Metabolomics
Least-Squares Analysis
Mass spectrometry
nuclear magnetic resonance
cancer

Rapid and sensitive detection of chemical explosives using ambient mass spectrometry

Chen, H. & Gu, H., Feb 1 2011, Explosive Materials: Classification, Composition and Properties. Nova Science Publishers, Inc., p. 81-101 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Explosives detection
Mass spectrometry
Electrospray ionization
Ionization
Desorption
2010
28 Citations (Scopus)

Fast Quantitative Detection of Cocaine in Beverages Using Nanoextractive Electrospray Ionization Tandem Mass Spectrometry

Hu, B., Peng, X., Yang, S., Gu, H., Chen, H., Huan, Y., Zhang, T. & Qiao, X., Feb 1 2010, In : Journal of the American Society for Mass Spectrometry. 21, 2, p. 290-293 4 p.

Research output: Contribution to journalArticle

Electrospray ionization
Beverages
Electrospray Ionization Mass Spectrometry
Tandem Mass Spectrometry
Cocaine
28 Citations (Scopus)

Geometry-independent neutral desorption device for the sensitive EESI-MS detection of explosives on various surfaces

Gu, H., Yang, S., Li, J., Hu, B., Chen, H., Zhang, L. & Fei, Q., Mar 29 2010, In : Analyst. 135, 4, p. 779-788 10 p.

Research output: Contribution to journalArticle

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Mass spectrometry
explosive
Desorption
27 Citations (Scopus)

Rapid analysis of aerosol drugs using nano extractive electrospray ionization tandem mass spectrometry

Gu, H., Hu, B., Li, J., Yang, S., Han, J. & Chen, H., Jun 1 2010, In : Analyst. 135, 6, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Tandem Mass Spectrometry
Aerosols
Mass spectrometry
2009
43 Citations (Scopus)

1H NMR metabolomics study of age profiling in children

Gu, H., Pan, Z., Xi, B., Hainline, B. E., Shanaiah, N., Asiago, V., Gowda, G. A. N. & Raftery, D., Dec 2 2009, In : NMR in Biomedicine. 22, 8, p. 826-833 8 p.

Research output: Contribution to journalArticle

Metabolomics
Metabolites
Creatinine
Nuclear magnetic resonance
Urine
24 Citations (Scopus)

Desorption electrospray ionization tandem mass spectrometry for detection of 24 carcinogenic aromatic amines in textiles

Yang, S., Han, J., Huan, Y., Cui, Y., Zhang, X., Chen, H. & Gu, H., Aug 1 2009, In : Analytical Chemistry. 81, 15, p. 6070-6079 10 p.

Research output: Contribution to journalArticle

Electrospray ionization
Amines
Mass spectrometry
Desorption
Textiles
42 Citations (Scopus)

Imaging melamine in Egg samples by surface desorption atmospheric pressure chemical ionization tandem mass spectrometry

Yang, S. P., Chen, H. W., Yang, Y. L., Hu, B., Zhang, X., Zhou, Y. F., Zhang, L. L. & Gu, H., Jan 1 2009, In : Fenxi Huaxue/ Chinese Journal of Analytical Chemistry. 37, 3, p. 315-318 4 p.

Research output: Contribution to journalArticle

Atmospheric pressure
Ionization
Mass spectrometry
Desorption
Imaging techniques
38 Citations (Scopus)

Selective detection of diethylene glycol in toothpaste products using neutral desorption reactive extractive electrospray ionization tandem mass spectrometry

Ding, J., Gu, H., Yang, S., Li, M., Li, J. & Chen, H., Oct 15 2009, In : Analytical Chemistry. 81, 20, p. 8632-8638 7 p.

Research output: Contribution to journalArticle

Toothpastes
Electrospray ionization
Mass spectrometry
Desorption
diethylene glycol
2008
326 Citations (Scopus)

Metabolomics-based methods for early disease diagnostics

Gowda, G. A. N., Zhang, S., Gu, H., Asiago, V., Shanaiah, N. & Raftery, D., Sep 1 2008, In : Expert Review of Molecular Diagnostics. 8, 5, p. 617-633 17 p.

Research output: Contribution to journalReview article

Metabolomics
Mass Spectrometry
Inborn Errors Metabolism
Statistical Data Interpretation
Translational Medical Research
2007
6 Citations (Scopus)

1H NMR study of the effects of sample contamination in the metabolomic analysis of mouse urine

Gu, H., Pan, Z., Duda, C., Mann, D., Kissinger, C., Rohde, C. & Raftery, D., Sep 21 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 45, 1, p. 134-140 7 p.

Research output: Contribution to journalArticle

Metabolomics
Contamination
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Urine
100 Citations (Scopus)

Differentiation of maturity and quality of fruit using noninvasive extractive electrospray ionization quadrupole time-of-flight mass spectrometry

Chen, H., Sun, Y., Wortmann, A., Gu, H. & Zenobi, R., Feb 15 2007, In : Analytical Chemistry. 79, 4, p. 1447-1455 9 p.

Research output: Contribution to journalArticle

Electrospray ionization
Fruits
Mass spectrometry
Principal component analysis
Vegetables
87 Citations (Scopus)

Monitoring diet effects via biofluids and their implications for metabolomics studies

Gu, H., Chen, H., Pan, Z., Jackson, A. U., Talaty, N., Xi, B., Kissinger, C., Duda, C., Mann, D., Raftery, D. & Cooks, R. G., Jan 1 2007, In : Analytical Chemistry. 79, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

Nutrition
Metabolites
Monitoring
Mass spectrometry
Rats
120 Citations (Scopus)

Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism

Pan, Z., Gu, H., Talaty, N., Chen, H., Shanaiah, N., Hainline, B. E., Cooks, R. G. & Raftery, D., Jan 1 2007, In : Analytical and Bioanalytical Chemistry. 387, 2, p. 539-549 11 p.

Research output: Contribution to journalArticle

Inborn Errors Metabolism
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Metabolites
Principal Component Analysis