• 5735 Citations
  • 44 h-Index
1973 …2022
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Research Output 1973 2017

2017
1 Citation (Scopus)

Hydrothermal pretreatment: Process modeling and economic assessment within the framework of biorefinery processes

Torres, A. I., Ashraf, M. T., Chaturvedi, T., Schmidt, J. E. & Stephanopoulos, G., Jun 1 2017, Hydrothermal Processing in Biorefineries: Production of Bioethanol and High Added-Value Compounds of Second and Third Generation Biomass. Springer International Publishing, p. 207-235 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Economics

OPTIMIZING CONTROL OF INDUSTRIAL CHEMICAL PROCESSES: STATE OF THE ART REVIEW.

Arkun, Y. & Stephanopoulos, G., Jan 1 2017.

Research output: Contribution to conferencePaper

Chemical Phenomena
Industrial chemicals
industrial applications
Control theory
Industrial applications

VARIABLE CONTROL STRUCTURES.

Romagnoli, J. A., Alvarez, J. & Stephanopoulos, G., Jan 1 2017.

Research output: Contribution to conferencePaper

Variable structure control
process control
Process control
Identification (control systems)
Tuning
2016
4 Citations (Scopus)

Design of multi-actor distributed processing systems: A game-theoretical approach

Torres, A. I. & Stephanopoulos, G., Jan 1 2016, In : AICHE Journal. 62, 9, p. 3369-3391 23 p.

Research output: Contribution to journalArticle

Computer Communication Networks
Processing
Process design
1 Citation (Scopus)

Economically optimal multi-actor processing networks: material flows and price assignment of the intermediates using Lagrangian decomposition

Torres, A. I., Bochenski, T., Schmidt, J. E. & Stephanopoulos, G., Jan 1 2016, 26 European Symposium on Computer Aided Process Engineering, 2016. Kravanja, Z. & Bogataj, M. (eds.). Elsevier B.V., p. 1383-1388 6 p. (Computer Aided Chemical Engineering; vol. 38).

Research output: Chapter in Book/Report/Conference proceedingChapter

Profitability
Decomposition
Processing
4 Citations (Scopus)

Evaluation of the production of lipids for fuels and proteins from microalgae by decomposition of the processing network

Bocheński, T., Torres, A. I., Ashraf, M. T., Schmidt, J. E. & Stephanopoulos, G., Jan 1 2016, 26 European Symposium on Computer Aided Process Engineering, 2016. Kravanja, Z. & Bogataj, M. (eds.). Elsevier B.V., p. 1635-1640 6 p. (Computer Aided Chemical Engineering; vol. 38).

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipids
Decomposition
Proteins
Profitability
Processing
2 Citations (Scopus)

Optimization of Lignocellulosic Waste Biorefinery using Multi-Actor Multi-Objective Mathematical Framework

Ashraf, M. T., Torres, A. I., Cybulska, I., Fang, C., Thomsen, M. H., Schmidt, J. E. & Stephanopoulos, G., Jan 1 2016, 26 European Symposium on Computer Aided Process Engineering, 2016. Kravanja, Z. & Bogataj, M. (eds.). Elsevier B.V., p. 1317-1322 6 p. (Computer Aided Chemical Engineering; vol. 38).

Research output: Chapter in Book/Report/Conference proceedingChapter

Succinic Acid
Sugars
Sales
Ethanol
Acids
2015
6 Citations (Scopus)

A Novel Approach for the Identification of Economic Opportunities within the Framework of a Biorefinery

Torres, A. I., Cybulska, I., Fang, C. J., Thomsen, M. H., Schmidt, J. E. & Stephanopoulos, G., Jan 1 2015, In : Computer Aided Chemical Engineering. 37, p. 1175-1180 6 p.

Research output: Contribution to journalArticle

Decomposition
Economics
6 Citations (Scopus)
Self assembly
Nanostructures
Nanoparticles
Geometry
Kinetics
2 Citations (Scopus)
Self assembly
Nanostructures
Nanoparticles
Geometry
Kinetics
1 Citation (Scopus)

Exploring Opportunities for the Production of Chemicals from Municipal Solid Wastes within the Framework of a Biorefinery

Bonk, F., Chaturvedi, T., Torres, A. I., Schmidt, J. E., Thomsen, M. H. & Stephanopoulos, G., Jan 1 2015, In : Computer Aided Chemical Engineering. 37, p. 2123-2128 6 p.

Research output: Contribution to journalArticle

Municipal solid waste
Biomass
Enzymatic hydrolysis
Biomolecules
Fermentation
2014
49 Citations (Scopus)

A system-theoretic, control-inspired view and approach to process safety

Leveson, N. G. & Stephanopoulos, G., Jan 1 2014, In : AICHE Journal. 60, 1, p. 2-14 13 p.

Research output: Contribution to journalEditorial

Process engineering
Process control
Control systems
Safety
1 Citation (Scopus)

Laying the foundations: An advisor's perspective

Stephanopoulos, G., Nov 5 2014, In : Computers and Chemical Engineering. 70, p. 3-10 8 p.

Research output: Contribution to journalArticle

Control theory
Chemical plants
Trajectories
Controllers
Direction compound

Principles and Methodologies for the Controlled Formation of Self-Assembled Nanoscale Structures with Desired Geometries

Solis, E. O. P., Barton, P. I. & Stephanopoulos, G., Jun 13 2014, Molecular Systems Engineering. Wiley, Vol. 6-7. p. 233-265 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Phase space methods
Intelligent systems
Nanotechnology
Probability distributions
Probability density function
2013

A tribute to Neal R. Amundson

Harold, M. & Stephanopoulos, G., Sep 1 2013, In : AICHE Journal. 59, 9, 1 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Formal Order-of-magnitude Reasoning In Process Engineering

Mavrovouniotis, M. L. & Stephanopoulos, G., Sep 17 2013, Readings in Qualitative Reasoning About Physical Systems. Elsevier Inc., p. 323-336 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Process engineering
Flowcharting
Chemical plants
Planning
2012
11 Citations (Scopus)

A master-equation approach to simulate kinetic traps during directed self-assembly

Lakerveld, R., Stephanopoulos, G. & Barton, P. I., May 14 2012, In : Journal of Chemical Physics. 136, 18, 184109.

Research output: Contribution to journalArticle

Self assembly
self assembly
traps
Kinetics
kinetics
2011

Principles and Methodologies for the Controlled Formation of Self-Assembled Nanoscale Structures with Desired Geometries

Solis, E. O. P., Barton, P. I. & Stephanopoulos, G., Jun 27 2011, Process Systems Engineering. Wiley-VCH, Vol. 6. p. 233-265 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nanostructures
Geometry
Monte Carlo simulation
101 Citations (Scopus)
Process engineering
Biotechnology
Systems engineering
Nanotechnology
Chemical engineering
1 Citation (Scopus)

Towards robust fabrication of non-periodic nanoscale systems via directed self assembly

Lakerveld, R., Stephanopoulos, G. & Barton, P. I., Jun 20 2011, In : Computer Aided Chemical Engineering. 29, p. 1603-1607 5 p.

Research output: Contribution to journalArticle

Self assembly
Fabrication
Potential energy surfaces
Dynamic models
Nanoparticles
2010
25 Citations (Scopus)

Controlled formation of nanostructures with desired geometries. 2. Robust dynamic paths

Solis, E. O. P., Barton, P. I. & Stephanopoulos, G., Sep 1 2010, In : Industrial and Engineering Chemistry Research. 49, 17, p. 7746-7757 12 p.

Research output: Contribution to journalArticle

Nanostructures
Geometry
Self assembly
Statistical mechanics
Energy barriers
2009

Controlled formation of self-assembled nanostructures with desired geometries: Robust dynamic paths to robust desired structures

Solis, E. O. P., Barton, P. I. & Stephanopoulos, G., Jan 1 2009, In : Computer Aided Chemical Engineering. 27, C, p. 1713-1718 6 p.

Research output: Contribution to journalArticle

Nanostructures
Self assembly
Geometry
2 Citations (Scopus)
Process engineering
Systems engineering
Chemical industry
Chemical engineering
Processing
2008
16 Citations (Scopus)

Multiscale theory for linear dynamic processes. Part 1. Foundations

Stephanopoulos, G., Karsligil, O. & Dyer, M. S., Apr 5 2008, In : Computers and Chemical Engineering. 32, 4-5, p. 857-884 28 p.

Research output: Contribution to journalArticle

Model predictive control
Dynamical systems
Multivariable control systems
Wavelet decomposition
Observability
11 Citations (Scopus)

Multiscale theory for linear dynamic processes. Part 2. Multiscale model predictive control (MS-MPC)

Stephanopoulos, G., Karsligil, O. & Dyer, M., Apr 5 2008, In : Computers and Chemical Engineering. 32, 4-5, p. 885-912 28 p.

Research output: Contribution to journalArticle

Model predictive control
Binary trees
Feedback control
Process control
Sampling

Success and prospects in process systems

Stephanopoulos, G., Dec 1 2008, AIChE100 - 2008 AIChE Annual Meeting, Conference Proceedings.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2007
4 Citations (Scopus)

Linking physiology and transcriptional profiles by quantitative predictive models

Misra, J., Alevizos, I., Hwang, D., Stephanopoulos, G. & Stephanopoulos, G., Sep 1 2007, In : Biotechnology and Bioengineering. 98, 1, p. 252-260 9 p.

Research output: Contribution to journalArticle

Physiology
Genes
Obese Mice
Microarrays
Nutrition
2006
1 Citation (Scopus)

The multiscale nature of process dynamics and model-predictive control

Karsligil, O. I. & Stephanopoulos, G., Dec 1 2006, Proceedings of the World Congress on Intelligent Control and Automation (WCICA). Vol. 1. 1713393

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Model predictive control
State estimation
Control systems
Controllers
2005
39 Citations (Scopus)

Nanoscale process systems engineering: Toward molecular factories, synthetic cells, and adaptive devices

Stephanopoulos, N., Solls, E. O. P. & Stephanopoulos, G., Jul 2005, In : AICHE Journal. 51, 7, p. 1858-1869 12 p.

Research output: Contribution to journalArticle

Artificial Cells
Process engineering
Systems engineering
Industrial plants
Equipment and Supplies
9 Citations (Scopus)

Topological coarse graining of polymer chains using wavelet-accelerated Monte Carlo. I. Freely jointed chains

Ismail, A. E., Rutledge, G. C. & Stephanopoulos, G., Jun 15 2005, In : Journal of Chemical Physics. 122, 23, 234901.

Research output: Contribution to journalArticle

Wavelet transforms
Polymers
beads
polymers
wavelet analysis
220 Citations (Scopus)

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis

Camelo, S., Iglesias, A. H., Hwang, D., Due, B., Ryu, H., Smith, K., Gray, S. G., Imitola, J., Duran, G., Assaf, B., Langley, B., Khoury, S. J., Stephanopoulos, G., De Girolami, U., Ratan, R. R., Ferrante, R. J. & Dangond, F., Jul 1 2005, In : Journal of Neuroimmunology. 164, 1-2, p. 10-21 12 p.

Research output: Contribution to journalArticle

trichostatin A
Histone Deacetylase Inhibitors
Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
E2F Transcription Factors
9 Citations (Scopus)

Using wavelet transforms for multiresolution materials modeling

Ismail, A. E., Rutledge, G. C. & Stephanopoulos, G., Mar 15 2005, In : Computers and Chemical Engineering. 29, 4, p. 689-700 12 p.

Research output: Contribution to journalReview article

Wavelet transforms
Polymers
Sampling

Wavelet-accelerated Monte Carlo sampling of polymer chains

Ismail, A. E., Stephanopoulos, G. & Rutledge, G. C., Apr 15 2005, In : Journal of Polymer Science, Part B: Polymer Physics. 43, 8, p. 897-910 14 p.

Research output: Contribution to journalArticle

Wavelet transforms
Polymers
Monte Carlo methods
sampling
Sampling
2004

A new wavelet-based paradigm for hierarchical coarse-graining applied to materials modeling

Ismail, A. E., Rutledge, G. C. & Stephanopoulos, G., Nov 29 2004, Proceedings of the 2004 American Control Conference (AAC). Vol. 1. p. 920-925 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wavelet transforms
Sampling
Polymers

Characteristics of parameter reduction in multiscale simulations of polymer chains

Ismail, A. E., Stephanopoulos, G. & Rutledge, G. C., Dec 1 2004, p. 10701-10702. 2 p.

Research output: Contribution to conferencePaper

Polymers
Bond length
Torsional stress

Characteristics of parameter reduction in multiscale simulations of polymer chainsx

Ismail, A. E., Stephanopoulos, G. & Rutledge, G. C., Dec 1 2004, p. 6259-6260. 2 p.

Research output: Contribution to conferencePaper

Scaling laws
Polymers
Monte Carlo simulation
12 Citations (Scopus)

Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data

Lee, K., Hwang, D., Yokoyama, T., Stephanopoulos, G., Stephanopoulos, G. N. & Yarmush, M. L., Apr 12 2004, In : Bioinformatics. 20, 6, p. 959-969 11 p.

Research output: Contribution to journalArticle

Galactosamine
Profiling
Liver
Discrimination
Metabolites
20 Citations (Scopus)

Inverse modeling using multi-block PLS to determine the environmental conditions that provide optimal cellular function

Hwang, D., Stephanopoulos, G. & Chan, C., Mar 1 2004, In : Bioinformatics. 20, 4, p. 487-499 13 p.

Research output: Contribution to journalArticle

Inverse Modeling
Multiblock
Environmental Factors
Least-Squares Analysis
Partial Least Squares
57 Citations (Scopus)

Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells

Iglesias, A. H., Camelo, S., Hwang, D., Villanueva, R., Stephanopoulos, G. & Dangond, F., May 1 2004, In : Journal of Neuroimmunology. 150, 1-2, p. 163-177 15 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Blood Cells
Autoimmune Experimental Encephalomyelitis
Autoantigens
Microarray Analysis
108 Citations (Scopus)

Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter

Dangond, F., Hwang, D., Camelo, S., Pasinelli, P., Frosch, M. P., Stephanopoulos, G., Stephanopoulos, G., Brown, R. H. & Gullans, S. R., Apr 1 2004, In : Physiological Genomics. 16, p. 229-239 11 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Spinal Cord
Oligonucleotide Array Sequence Analysis
Genes
Discriminant Analysis

Preface to the "Art Westerberg" festschrift

Hrymak, A. & Stephanopoulos, G., Sep 15 2004, In : Computers and Chemical Engineering. 28, 10, 1 p.

Research output: Contribution to journalEditorial

2003
42 Citations (Scopus)

Application of multivariate analysis to optimize function of cultured hepatocytes

Chan, C., Hwang, D., Stephanopoulos, G. N., Yarmush, M. L. & Stephanopoulos, G., Mar 1 2003, In : Biotechnology Progress. 19, 2, p. 580-598 19 p.

Research output: Contribution to journalArticle

hepatocytes
multivariate analysis
liver function
Hepatocytes
Multivariate Analysis
30 Citations (Scopus)

Genomic dissection for characterization of cancerous oral epithelium tissues using transcription profiling

Hwang, D., Alevizos, I., Schmitt, W. A., Misra, J., Ohyama, H., Todd, R., Mahadevappa, M., Warrington, J. A., Stephanopoulos, G., Wong, D. T. & Stephanopoulos, G., Apr 1 2003, In : Oral Oncology. 39, 3, p. 259-268 10 p.

Research output: Contribution to journalArticle

Dissection
Epithelium
Genes
Mouth Neoplasms
Discriminant Analysis
48 Citations (Scopus)

Multiresolution analysis in statistical mechanics. I. Using wavelets to calculate thermodynamic properties

Ismail, A. E., Rutledge, G. C. & Stephanopoulos, G., Mar 8 2003, In : Journal of Chemical Physics. 118, 10, p. 4414-4423 10 p.

Research output: Contribution to journalArticle

Multiresolution analysis
Statistical mechanics
statistical mechanics
wavelet analysis
Wavelet transforms
41 Citations (Scopus)

Multiresolution analysis in statistical mechanics. II. The wavelet transform as a basis for Monte Carlo simulations in lattices

Ismail, A. E., Stephanopoulos, G. & Rutledge, G. C., Mar 8 2003, In : Journal of Chemical Physics. 118, 10, p. 4424-4431 8 p.

Research output: Contribution to journalArticle

Hamiltonians
Multiresolution analysis
Statistical mechanics
statistical mechanics
wavelet analysis
2002

A compendium of gene expression in normal human tissues

Hsiao, L. L., Dangond, F., Yoshida, T., Hong, R., Jensen, R. V., Misra, J., Dillon, W., Lee, K. F., Clark, K. E., Haverty, P., Weng, Z., Mutter, G. L., Frosch, M. P., MacDonald, M. E., Milford, E. L., Crum, C. P., Bueno, R., Pratt, R. E., Mahadevappa, M., Warrington, J. A. & 3 others, Stephanopoulos, G., Stephanopoulos, G. & Gullans, S. R., Jan 1 2002, In : Physiological Genomics. 2002, 7, p. 97-104 8 p.

Research output: Contribution to journalArticle

Gene Expression
Genes
Biochemical Phenomena
Biological Phenomena
Systems Biology
94 Citations (Scopus)

Determination of minimum sample size and discriminatory expression patterns in microarray data

Hwang, D., Schmitt, W. A., Stephanopoulos, G. & Stephanopoulos, G., Jan 1 2002, In : Bioinformatics. 18, 9, p. 1184-1193 10 p.

Research output: Contribution to journalArticle

Discriminant analysis
Microarrays
Microarray Data
Sample Size
Power Analysis
117 Citations (Scopus)

Interactive exploration of microarray gene expression patterns in a reduced dimensional space

Misra, J., Schmitt, W., Hwang, D., Hsiao, L. L., Gullans, S., Stephanopoulos, G. & Stephanopoulos, G., Jul 30 2002, In : Genome Research. 12, 7, p. 1112-1120 9 p.

Research output: Contribution to journalArticle

Gene Expression
Genes
Principal Component Analysis
Oligonucleotide Array Sequence Analysis
Transcriptome
48 Citations (Scopus)

Mapping physiological states from microarray expression measurements

Stephanopoulos, G., Hwang, D., Schmitt, W. A., Misra, J. & Stephanopoulos, G., Jan 1 2002, In : Bioinformatics. 18, 8, p. 1054-1063 10 p.

Research output: Contribution to journalArticle

Microarrays
Microarray
Genes
DNA
Physiology

Metabolic profiling: Definition and use in physiological state classification

Lee, K., Hwang, D., Yarmush, M. L. & Stephanopoulos, G., Dec 1 2002, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 3, p. 2213-2214 2 p.

Research output: Contribution to journalConference article

Metabolites
Fluxes
Liver
Wounds and Injuries