• 2618 Citations
  • 28 h-Index
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Research Output 2001 2019

2019

Bioprospecting of Native Efflux Pumps To Enhance Furfural Tolerance in Ethanologenic Escherichia coli

Kurgan, G., Panyon, L. A., Rodriguez-Sanchez, Y., Pacheco, E., Nieves, L. M., Mann, R., Nielsen, D. & Wang, X., Mar 15 2019, In : Applied and environmental microbiology. 85, 6

Research output: Contribution to journalArticle

Furaldehyde
furfural
multiple drug resistance
Multiple Drug Resistance
transporters

Emerging tools, enabling technologies, and future opportunities for the bioproduction of aromatic chemicals

Machas, M., Kurgan, G., Jha, A. K., Flores, A., Schneider, A., Coyle, S., Varman, A., Wang, X. & Nielsen, D., Jan 1 2019, In : Journal of Chemical Technology and Biotechnology. 94, 1, p. 38-52 15 p.

Research output: Contribution to journalReview article

Cell Engineering
Technology
engineering
Lignin
Petroleum

Engineering a Synthetic, Catabolically Orthogonal Coculture System for Enhanced Conversion of Lignocellulose-Derived Sugars to Ethanol

Flores, A. D., Ayla, E. Z., Nielsen, D. & Wang, X., May 17 2019, In : ACS Synthetic Biology. 8, 5, p. 1089-1099 11 p.

Research output: Contribution to journalArticle

Coculture Techniques
Sugars
Fermentation
Xylose
Ethanol

Recent trends in integrated bioprocesses: aiding and expanding microbial biofuel/biochemical production

Flores, A., Wang, X. & Nielsen, D., Jun 1 2019, In : Current Opinion in Biotechnology. 57, p. 82-87 6 p.

Research output: Contribution to journalReview article

Biofuels
Biosynthesis
Toxicity
Innovation
Catalysts
2018
3 Citations (Scopus)

Catalytic conversion of cyanobacteria-derived fatty acids to alkanes for biorenewable synthetic paraffinic kerosene

Schulz, T. C., Oelschlager, M., Thompson, S. T., Vermaas, W., Nielsen, D. & Lamb, H. H., Jan 1 2018, In : Sustainable Energy and Fuels. 2, 4, p. 882-893 12 p.

Research output: Contribution to journalArticle

Open Access
Kerosene
Fatty acids
Paraffins
Purification
Acids
9 Citations (Scopus)

Muconic Acid Production via Alternative Pathways and a Synthetic "metabolic Funnel"

Thompson, B., Pugh, S., Machas, M. & Nielsen, D., Feb 16 2018, In : ACS Synthetic Biology. 7, 2, p. 565-575 11 p.

Research output: Contribution to journalArticle

Acids
Phenols
Biosynthesis
phenol 2-monooxygenase
Phenol
2017
7 Citations (Scopus)

Expanding Upon Styrene Biosynthesis to Engineer a Novel Route to 2-Phenylethanol

Machas, M. S., Mckenna, R. & Nielsen, D., 2017, (Accepted/In press) In : Biotechnology Journal.

Research output: Contribution to journalArticle

Phenylethyl Alcohol
Styrene
Phenylalanine
Escherichia coli
Phosphoenolpyruvate
7 Citations (Scopus)

High Efficiency and Facile Butanol Recovery with Magnetically Responsive Micro/Mesoporous Carbon Adsorbents

Staggs, K. W., Qiang, Z., Madathil, K., Gregson, C., Xia, Y., Vogt, B. & Nielsen, D., Jan 3 2017, In : ACS Sustainable Chemistry and Engineering. 5, 1, p. 885-894 10 p.

Research output: Contribution to journalArticle

Butanols
Butenes
Adsorbents
Carbon
Recovery
2016
11 Citations (Scopus)

Engineering and comparison of non-natural pathways for microbial phenol production

Thompson, B., Machas, M. & Nielsen, D., Aug 1 2016, In : Biotechnology and Bioengineering. 113, 8, p. 1745-1754 10 p.

Research output: Contribution to journalArticle

Phenol
Phenols
Tyrosine Phenol-Lyase
Biosynthesis
Hydroxybenzoates
1 Citation (Scopus)

Engineering Central Metabolism for Production of Higher Alcohol-based Biofuels

Immethun, C. M., Henson, W. R., Wang, X., Nielsen, D. & Moon, T. S., Jan 20 2016, Biotechnology for Biofuel Production and Optimization. Elsevier Inc., p. 1-34 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biofuels
Metabolism
Alcohols
Bioethanol
Availability

Engineering membrane phospholipids increases E. coli robustness and production of biorenewables

Tan, Z., Yoon, J. M., Chen, Y., Lombardo, J., Nielsen, D., Shanks, J. V. & Jarboe, L., 2016, Metabolic Engineering 11. AIChE, p. 766-767 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Escherichia coli
Phospholipids
Membranes
32 Citations (Scopus)

Membrane engineering via trans unsaturated fatty acids production improves Escherichia coli robustness and production of biorenewables

Tan, Z., Yoon, J. M., Nielsen, D., Shanks, J. V. & Jarboe, L. R., May 1 2016, In : Metabolic Engineering. 35, p. 105-113 9 p.

Research output: Contribution to journalArticle

Unsaturated fatty acids
Trans Fatty Acids
Unsaturated Fatty Acids
Escherichia coli
Membranes
22 Citations (Scopus)

Production of biorenewable styrene: utilization of biomass-derived sugars and insights into toxicity

Lian, J., McKenna, R., Rover, M. R., Nielsen, D., Wen, Z. & Jarboe, L. R., Jan 23 2016, (Accepted/In press) In : Journal of Industrial Microbiology and Biotechnology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Styrene
Sugars
Biomass
Toxicity
Membranes
2015
4 Citations (Scopus)

Activity of Lactobacillus brevis alcohol dehydrogenase on primary and secondary alcohol biofuel precursors

Halloum, I., Thompson, B., Pugh, S. & Nielsen, D., Dec 1 2015, In : Fermentation. 1, 1, p. 24-37 14 p.

Research output: Contribution to journalArticle

Open Access
Lactobacillus brevis
Biofuels
Alcohol Dehydrogenase
alcohol dehydrogenase
biofuels
19 Citations (Scopus)

Comparing in situ removal strategies for improving styrene bioproduction

McKenna, R., Moya, L., McDaniel, M. & Nielsen, D., Jan 1 2015, In : Bioprocess and Biosystems Engineering. 38, 1, p. 165-174 10 p.

Research output: Contribution to journalArticle

Styrene
Gases
Solvent extraction
Escherichia coli
Toxicity
12 Citations (Scopus)

Creating pathways towards aromatic building blocks and fine chemicals

Thompson, B., Machas, M. & Nielsen, D., Dec 1 2015, In : Current Opinion in Biotechnology. 36, p. 1-7 7 p.

Research output: Contribution to journalArticle

Synthetic Biology
Metabolic Engineering
Petroleum
Enzymes
Metabolic engineering
18 Citations (Scopus)

Engineering Escherichia coli for renewable benzyl alcohol production

Pugh, S., McKenna, R., Halloum, I. & Nielsen, D., Dec 1 2015, In : Metabolic Engineering Communications. 2, p. 39-45 7 p.

Research output: Contribution to journalArticle

Benzyl Alcohol
Escherichia coli
Alcohols
Biosynthesis
Glucose
27 Citations (Scopus)

Improving n-butanol production in batch and semi-continuous processes through integrated product recovery

Staggs, K. W. & Nielsen, D., Apr 20 2015, In : Process Biochemistry. 50, 10, p. 1487-1498 12 p.

Research output: Contribution to journalArticle

1-Butanol
Butenes
Recovery
Fermentation
Volatilization
2014
3-Hydroxybutyric Acid
Cyanobacteria
corrigendum

Engineering alternative and non-natural routes to aromatic alcohols

Thompson, B., Pugh, S., McKenna, R. & Nielsen, D., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, Vol. 1. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Alcohols
7 Citations (Scopus)

'Hybrid' processing strategies for expanding and improving the synthesis of renewable bioproducts

Thompson, B., Moon, T. S. & Nielsen, D., 2014, In : Current Opinion in Biotechnology. 30, p. 17-23 7 p.

Research output: Contribution to journalArticle

Biomass
Metabolic Engineering
Biocatalysts
Biosynthesis
Petroleum
30 Citations (Scopus)

In situ butanol recovery from Clostridium acetobutylicum fermentations by expanded bed adsorption

Wiehn, M., Staggs, K., Wang, Y. & Nielsen, D., Jan 2014, In : Biotechnology Progress. 30, 1, p. 68-78 11 p.

Research output: Contribution to journalArticle

Clostridium acetobutylicum
Butanols
Adsorption
Fermentation
Biofouling
28 Citations (Scopus)

Rational and combinatorial approaches to engineering styrene production by Saccharomyces cerevisiae

McKenna, R., Thompson, B., Pugh, S. & Nielsen, D., 2014, In : Microbial Cell Factories. 13, p. 123 1 p.

Research output: Contribution to journalArticle

Styrene
Yeast
Saccharomyces cerevisiae
3-Deoxy-7-Phosphoheptulonate Synthase
Phenylalanine
19 Citations (Scopus)

Rational engineering of a novel pathway for producing the aromatic compounds p-hydroxybenzoate, protocatechuate, and catechol in Escherichia coli

Pugh, S., McKenna, R., Osman, M., Thompson, B. & Nielsen, D., 2014, In : Process Biochemistry. 49, 11, p. 1843-1850 8 p.

Research output: Contribution to journalArticle

Aromatic compounds
Biosynthesis
Escherichia coli
Glucose
Bioreactors
5 Citations (Scopus)

Synthetic biology applications in industrial microbiology

Zhang, W. & Nielsen, D., 2014, In : Frontiers in Microbiology. 5, AUG, 00451.

Research output: Contribution to journalEditorial

Industrial Microbiology
Synthetic Biology
Biotechnology
17 Citations (Scopus)

Technoeconomic evaluation of bio-based styrene production by engineered Escherichia coli

Claypool, J. T., Raman, D. R., Jarboe, L. R. & Nielsen, D., 2014, In : Journal of Industrial Microbiology and Biotechnology. 41, 8, p. 1211-1216 6 p.

Research output: Contribution to journalArticle

Styrene
Escherichia coli
Feedstocks
Sales
Sugars
2013
8 Citations (Scopus)

Adsorption of short-chain alcohols by hydrophobic silica aerogels

Wiehn, M., Levario, T. J., Staggs, K., Linneen, N., Wang, Y., Pfeffer, R., Lin, J. & Nielsen, D., Dec 26 2013, In : Industrial and Engineering Chemistry Research. 52, 51, p. 18379-18385 7 p.

Research output: Contribution to journalArticle

Aerogels
Silicon Dioxide
Alcohols
Silica
Adsorption

Catalytic deoxygenation of cyanobacteria-derived fatty acids to hydrocarbons

Schulz, T., Oelschlager, M., Nielsen, D., Vermaas, W. & Lamb, H. H., 2013, Fuels and Petrochemicals Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 264-265 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fatty acids
Hydrocarbons
Cyanobacteria

Catalytic Deoxygenation of Cyanobacteria-Derived Fatty Acids to Hydrocarbons

Schultz, T., Oelschlager, M., Nielsen, D. R., Vermaas, W. & Lamb, H., 2013, Catalytic Deoxygenation of Cyanobacteria-Derived Fatty Acids to Hydrocarbons.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Comparison of Non-Natural Pathways for Phenol Biosynthesis in Engineered Escherichia Coli

Thompson, B., Pugh, S., McKenna, R. & Nielsen, D. R., 2013, Comparison of Non-Natural Pathways for Phenol Biosynthesis in Engineered Escherichia Coli.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Developing Sustainable Routes to Novel Aromatic Biochemicals through Pathway Engineering

McKenna, R., Pugh, S., Thompson, B. & Nielsen, D. R., 2013, Developing Sustainable Routes to Novel Aromatic Biochemicals through Pathway Engineering.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Engineering Cyanobacteria for Continuous Production of 3-Hydroxybutyrate Directly from CO2

Wang, B., Pugh, S., Nielsen, D. R., Zhang, W. & Meldrum, D., 2013, In : Metab. Eng.. 16, p. 68-77

Research output: Contribution to journalArticle

92 Citations (Scopus)

Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2

Wang, B., Pugh, S., Nielsen, D., Zhang, W. & Meldrum, D., Mar 2013, In : Metabolic Engineering. 16, 1, p. 68-77 10 p.

Research output: Contribution to journalArticle

3-Hydroxybutyric Acid
Cyanobacteria
Synechocystis
Biosynthesis
Chemical industry
38 Citations (Scopus)

Engineering Escherichia coli for renewable production of the 5-carbon polyamide building-blocks 5-aminovalerate and glutarate

Adkins, J., Jordan, J. & Nielsen, D. R., Jun 2013, In : Biotechnology and Bioengineering. 110, 6, p. 1726-1734 9 p.

Research output: Contribution to journalArticle

Glutarates
Nylons
Polyamides
Escherichia coli
Lysine
38 Citations (Scopus)

Engineering Escherichia coli for Renewable Production of the 5- Carbon Polyamide Building-Blocks 5-Aminovalerate and Glutarate

Adkins, J., Jordan, J. & Nielsen, D. R., 2013, In : Biotechnol. Bioeng. 110, p. 1726-1734

Research output: Contribution to journalArticle

Engineering Styrene Biosynthesis in Yeast Via Rational and Combinatorial Approaches

McKenna, R., Pugh, S., Thompson, B. & Nielsen, D. R., 2013, Engineering Styrene Biosynthesis in Yeast Via Rational and Combinatorial Approaches.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

From promise to practice

Nielsen, D. & Moon, T. S., Dec 2013, In : EMBO Reports. 14, 12, p. 1034-1038 5 p.

Research output: Contribution to journalArticle

Synthetic Biology
3 Citations (Scopus)

From Promise to Practice. The Role of Synthetic Biology in Green Chemistry

Nielsen, D. R. & Moon, T. S., 2013, In : EMBO Reports.

Research output: Contribution to journalArticle

Microbial production of 5-carbon polyamide building blocks

Adkins, J., Wang, B., Wu, T. & Nielsen, D. R., 2013, Microbial production of 5-carbon polyamide building blocks.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

19 Citations (Scopus)

Microbial production of the aromatic building-blocks (S)-styrene oxide and (R)-1,2-phenylethanediol from renewable resources

Mckenna, R., Pugh, S., Thompson, B. & Nielsen, D. R., Dec 2013, In : Biotechnology Journal. 8, 12, p. 1465-1475 11 p.

Research output: Contribution to journalArticle

styrene oxide
Styrene
Dioxygenases
Pseudomonas putida
Poisons
19 Citations (Scopus)

Microbial Production of the Aromatic Building-Blocks (S)-Styrene Oxide and (R)-1,2-Phenylethanediol from Renewable Resources

McKenna, R., Pugh, S., Thompson, B. & Nielsen, D. R., 2013, In : Biotechnol. J..

Research output: Contribution to journalArticle

petrochemicals
phenol
catechol
chemical derivatives
feedstocks

Microorganisms Engineered to Produce Phenol and its Derivatives

Nielsen, D. R., Pugh, S. & Thompson, B., 2013

Research output: Patent

Pathway Engineering for the Renewable Production of 5-Aminovalerate and Glutarate

Adkins, J., Jordan, J. & Nielsen, D. R., 2013, Pathway Engineering for the Renewable Production of 5-Aminovalerate and Glutarate.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Renewable production of benzaldehyde and benzyl alcohol in engineered Escherichia coli

Pugh, S., McKenna, R., Thompson, B. & Nielsen, D. R., 2013, Renewable production of benzaldehyde and benzyl alcohol in engineered Escherichia coli.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Solid-phase extraction of long-chain fatty acids from aqueous solution

Yuan, W., Wiehn, M., Wang, Y., Kim, H. W., Rittmann, B. & Nielsen, D., 2013, In : Separation and Purification Technology. 106, p. 1-7 7 p.

Research output: Contribution to journalArticle

Laurates
Fatty acids
Adsorbents
Fatty Acids
Ion exchange
6 Citations (Scopus)

Solid-Phase Extraction of Long-Chain Fatty Acids from Aqueous Solution

Yuan, W., Wiehn, M., Wang, Y., Kim, H. W., Rittmann, B. E. & Nielsen, D. R., 2013, In : Sep. Purif. Technol.. 106, p. 1-7

Research output: Contribution to journalArticle

The economic potential of bio-based styrene from Escherichia coli

Claypool, J., Raman, D. R., Jarboe, L. J. & Nielsen, D. R., 2013, The economic potential of bio-based styrene from Escherichia coli.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The use of expanded-bed adsorption for in situ butanol removal and development of a semi-continuous fermentation process

Wiehn, M. & Nielsen, D. R., 2013, The use of expanded-bed adsorption for in situ butanol removal and development of a semi-continuous fermentation process.

Research output: Chapter in Book/Report/Conference proceedingConference contribution