• 6132 Citations
  • 43 h-Index
1900 …2019

Research output per year

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Research Output

2019

Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost

Asbach, B., Kibler, K., Köstler, J., Perdiguero, B., Yates, N. L., Stanfield-Oakley, S., Tomaras, G. D., Kao, S. F., Foulds, K. E., Roederer, M., Seaman, M. S., Montefiori, D. C., Parks, R., Ferrari, G., Forthal, D. N., Phogat, S., Tartaglia, J., Barnett, S. W., Self, S. G., Gottardo, R. & 9 others, Cristillo, A. D., Weiss, D. E., Galmin, L., Ding, S., Heeney, J. L., Esteban, M., Jacobs, B., Pantaleo, G. & Wagner, R., Feb 1 2019, In : Journal of virology. 93, 3

Research output: Contribution to journalArticle

10 Scopus citations

Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector

Giel-Moloney, M., Esteban, M., Oakes, B. H., Vaine, M., Asbach, B., Wagner, R., Mize, G. J., Spies, A. G., McElrath, J., Perreau, M., Roger, T., Ives, A., Calandra, T., Weiss, D., Perdiguero, B., Kibler, K. V., Jacobs, B., Ding, S., Tomaras, G. D., Montefiori, D. C. & 14 others, Ferrari, G., Yates, N. L., Roederer, M., Kao, S. F., Foulds, K. E., Mayer, B. T., Bennett, C., Gottardo, R., Parrington, M., Tartaglia, J., Phogat, S., Pantaleo, G., Kleanthous, H. & Pugachev, K. V., Dec 1 2019, In : Scientific reports. 9, 1, 20005.

Research output: Contribution to journalArticle

Open Access

Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC

Kibler, K., Asbach, B., Perdiguero, B., García-Arriaza, J., Yates, N. L., Parks, R., Stanfield-Oakley, S., Ferrari, G., Montefiori, D. C., Tomaras, G. D., Roederer, M., Foulds, K. E., Forthal, D. N., Seaman, M. S., Self, S., Gottardo, R., Phogat, S., Tartaglia, J., Barnett, S., Cristillo, A. D. & 8 others, Weiss, D., Galmin, L., Ding, S., Heeney, J. L., Esteban, M., Wagner, R., Pantaleo, G. & Jacobs, B., Feb 1 2019, In : Journal of virology. 93, 3

Research output: Contribution to journalArticle

5 Scopus citations
2018
5 Scopus citations

Immunization of pigs by DNA prime and recombinant vaccinia virus boost to identify and rank African swine fever virus immunogenic and protective proteins

Jancovich, J. K., Chapman, D., Hansen, D., Robida, M. D., Loskutov, A., Craciunescu, F., Borovkov, A., Kibler, K., Goatley, L., King, K., Netherton, C. L., Taylor, G., Jacobs, B., Sykes, K. & Dixon, L. K., Apr 1 2018, In : Journal of Virology. 92, 8, e02219-17.

Research output: Contribution to journalArticle

17 Scopus citations

Immunogenicity of NYVAC primeprotein boost human immunodeficiency virus type 1 envelope vaccination and simianhuman immunodeficiency virus challenge of nonhuman primates

Saunders, K. O., Santra, S., Parks, R., Yates, N. L., Sutherland, L. L., Scearce, R. M., Balachandran, H., Bradley, T., Goodman, D., Eaton, A., Stanfield-Oakley, S. A., Tartaglia, J., Phogat, S., Pantaleo, G., Esteban, M., Gomez, C. E., Perdiguero, B., Jacobs, B., Kibler, K., Korber, B. & 6 others, Montefiori, D. C., Ferrari, G., Vandergrift, N., Liao, H. X., Tomaras, G. D. & Haynes, B. F., Apr 1 2018, In : Journal of virology. 92, 8, e02035-17.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles

Meador, L. R., Kessans, S. A., Kilbourne, J., Kibler, K., Pantaleo, G., Roderiguez, M. E., Blattman, J., Jacobs, B. & Leket-Mor, T., Jul 1 2017, In : Virology. 507, p. 242-256 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Characterization of a PKR inhibitor from the pathogenic ranavirus, Ambystoma tigrinum virus, using a heterologous vaccinia virus system

Huynh, T. P., Jancovich, J. K., Tripuraneni, L., Heck, M. C., Langland, J. & Jacobs, B., Nov 1 2017, In : Virology. 511, p. 290-299 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

HIV/AIDS vaccine candidates based on replication-competent recombinant poxvirus NYVAC-C-KC expressing trimeric gp140 and Gag-derived virus-like particles or lacking the viral molecule B19 that inhibits type I interferon activate relevant HIV-1-specific B and T cell immune functions in nonhuman primates

García-Arriaza, J., Perdiguero, B., Heeney, J. L., Seaman, M. S., Montefiori, D. C., Yates, N. L., Tomaras, G. D., Ferrari, G., Foulds, K. E., Roederer, M., Self, S. G., Borate, B., Gottardo, R., Phogat, S., Tartaglia, J., Barnett, S. W., Burke, B., Cristillo, A. D., Weiss, D. E., Lee, C. & 6 others, Kibler, K., Jacobs, B., Wagner, R., Ding, S., Pantaleo, G. & Esteban, M., May 1 2017, In : Journal of virology. 91, 9, e02182-16.

Research output: Contribution to journalArticle

15 Scopus citations

Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

Koehler, H., Cotsmire, S., Langland, J., Kibler, K., Kalman, D., Upton, J. W., Mocarski, E. S. & Jacobs, B., Oct 24 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 43, p. 11506-11511 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Superiority in rhesus macaques of targeting HIV-1 Env gp140 to CD40 versus LOX-1 in combination with replication-competent NYVAC-KC for induction of Env-specific antibody and T cell responses

Zurawski, G., Shen, X., Zurawski, S., Tomaras, G. D., Montefiori, D. C., Roederer, M., Ferrari, G., Lacabaratz, C., Klucar, P., Wang, Z., Foulds, K. E., Kao, S. F., Yu, X., Sato, A., Yates, N. L., LaBranche, C., Stanfield-Oakley, S., Kibler, K., Jacobs, B., Salazar, A. & 8 others, Self, S., Fulp, W., Gottardo, R., Galmin, L., Weiss, D., Cristillo, A., Pantaleo, G. & Levy, Y., May 1 2017, In : Journal of virology. 91, 9, e01596-16.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Characterization of the physiological response following in vivo administration of astragalus membranaceus

Denzler, K., Moore, J., Harrington, H., Morrill, K., Huynh, T., Jacobs, B., Waters, R. & Langland, J., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 6861078.

Research output: Contribution to journalArticle

6 Scopus citations

Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus

Arndt, W. D., White, S. D., Johnson, B. P., Huynh, T., Liao, J., Harrington, H., Cotsmire, S., Kibler, K., Langland, J. & Jacobs, B., Oct 1 2016, In : Virology. 497, p. 125-135 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Potential to streamline heterologous DNA prime and NYVAC/protein boost HIV vaccine regimens in rhesus macaques by employing improved antigens

Asbach, B., Kliche, A., Köstler, J., Perdiguero, B., Esteban, M., Jacobs, B., Montefiori, D. C., LaBranche, C. C., Yates, N. L., Tomaras, G. D., Ferrari, G., Foulds, K. E., Roederer, M., Landucci, G., Forthal, D. N., Seaman, M. S., Hawkins, N., Self, S. G., Sato, A., Gottardo, R. & 12 others, Phogat, S., Tartaglia, J., Barnett, S. W., Burke, B., Cristillo, A. D., Weiss, D. E., Francis, J., Galmin, L., Ding, S., Heeney, J. L., Pantaleo, G. & Wagner, R., Apr 1 2016, In : Journal of virology. 90, 8, p. 4133-4149 17 p.

Research output: Contribution to journalArticle

18 Scopus citations

Selective Photonic Disinfection of Cell Culture Using a Visible Ultrashort Pulsed Laser

Tsen, S. W. D., Kibler, K., Jacobs, B., Fay, J. C., Podolnikova, N., Ugarova, T., Achilefu, S. & Tsen, K-T., May 1 2016, In : IEEE Journal on Selected Topics in Quantum Electronics. 22, 3, 7322185.

Research output: Contribution to journalArticle

3 Scopus citations

Targeting HIV-1 env gp140 to LOX-1 elicits immune responses in rhesus macaques

Zurawski, G., Zurawski, S., Flamar, A. L., Richert, L., Wagner, R., Tomaras, G. D., Montefiori, D. C., Roederer, M., Ferrari, G., Lacabaratz, C., Bonnabau, H., Klucar, P., Wang, Z., Foulds, K. E., Kao, S. F., Yates, N. L., LaBranche, C., Jacobs, B., Kibler, K., Asbach, B. & 11 others, Kliche, A., Salazar, A., Reed, S., Self, S., Gottardo, R., Galmin, L., Weiss, D., Cristillo, A., Thiebaut, R., Pantaleo, G. & Levy, Y., Apr 2016, In : PloS one. 11, 4, e0153484.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Comparison of immunogenicity in rhesus macaques of transmitted-founder, HIV-1 Group M consensus, and trivalent mosaic envelope vaccines formulated as a DNA prime, NYVAC, and envelope protein boost

Hulot, S. L., Korber, B., Giorgi, E. E., Vandergrift, N., Saunders, K. O., Balachandran, H., Mach, L. V., Lifton, M. A., Pantaleo, G., Tartaglia, J., Phogat, S., Jacobs, B., Kibler, K., Perdiguero, B., Gomez, C. E., Esteban, M., Rosati, M., Felber, B. K., Pavlakis, G. N., Parks, R. & 10 others, Lloyd, K., Sutherland, L., Scearce, R., Letvin, N. L., Seaman, M. S., Alam, S. M., Montefiori, D., Liao, H. X., Haynes, B. F. & Santra, S., Jan 1 2015, In : Journal of virology. 89, 12, p. 6462-6480 19 p.

Research output: Contribution to journalArticle

25 Scopus citations

Evasion of the innate immune type I interferon system by Monkeypox virus

Arndt, W. D., Cotsmire, S., Trainor, K., Harrington, H., Hauns, K., Kibler, K., Huynh, T. P. & Jacobs, B., 2015, In : Journal of Virology. 89, 20, p. 10489-10499 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Head-to-head comparison of poxvirus NYVAC and ALVAC vectors expressing identical HIV-1 clade C immunogens in prime-boost combination with Env protein in nonhuman primates

García-Arriaza, J., Perdiguero, B., Heeney, J., Seaman, M., Montefiori, D. C., Labranche, C., Yates, N. L., Shen, X., Tomaras, G. D., Ferrari, G., Foulds, K. E., McDermott, A., Kao, S. F., Roederer, M., Hawkins, N., Self, S., Yao, J., Farrell, P., Phogat, S., Tartaglia, J. & 12 others, Barnett, S. W., Burke, B., Cristillo, A., Weiss, D., Lee, C., Kibler, K., Jacobs, B., Asbach, B., Wagner, R., Ding, S., Pantaleo, G. & Esteban, M., Jan 1 2015, In : Journal of virology. 89, 16, p. 8525-8539 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Interaction between unrelated viruses during in vivo co-infection to limit pathology and immunity

McAfee, M. S., Huynh, T. P., Johnson, J. L., Jacobs, B. & Blattman, J., Oct 1 2015, In : Virology. 484, p. 153-162 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1

Mooij, P., Koopman, G., Drijfhout, J. W., Nieuwenhuis, I. G., Beenhakker, N., Koestler, J., Bogers, W. M. J. M., Wagner, R., Esteban, M., Pantaleo, G., Heeney, J. L., Jacobs, B. & Melief, C. J. M., 2015, In : Journal of General Virology. 96, p. 1478-1483 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Virological and immunological characterization of novel NYVAC-Based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles

Perdiguero, B., Gómez, C. E., Cepeda, V., Sánchez-Sampedro, L., García-Arriaza, J., Mejías-Pérez, E., Jiménez, V., Sánchez, C., Sorzano, C. Ó. S., Oliveros, J. C., Delaloye, J., Roger, T., Calandra, T., Asbach, B., Wagner, R., Kibler, K., Jacobs, B., Pantaleo, G. & Esteban, M., Jan 1 2015, In : Journal of virology. 89, 2, p. 970-988 19 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Pathogen reduction in human plasma using an ultrashort pulsed laser

Tsen, S. W. D., Kingsley, D. H., Kibler, K., Jacobs, B., Sizemore, S., Vaiana, S., Anderson, J., Tsen, K-T. & Achilefu, S., Nov 5 2014, In : PloS one. 9, 11, e111673.

Research output: Contribution to journalArticle

3 Scopus citations
2013

A leader sequence capable of enhancing RNA expression and protein synthesis in mammalian cells

Wellensiek, B. P., Larsen, A. C., Flores, J., Jacobs, B. & Chaput, J. C., Oct 1 2013, In : Protein Science. 22, 10, p. 1392-1398 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of an Undergraduate HIV/AIDS Course on Students' HIV Risk

Marsiglia, F., Jacobs, B., Nieri, T., Smith, S. J., Salamone, D. & Booth, J., Apr 1 2013, In : Journal of HIV/AIDS and Social Services. 12, 2, p. 172-189 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genome-wide profiling of human cap-independent translation-enhancing elements

Wellensiek, B. P., Larsen, A. C., Stephens, B., Kukurba, K., Waern, K., Briones, N., Liu, L., Snyder, M., Jacobs, B. L., Kumar, S. & Chaput, J. C., Aug 1 2013, In : Nature Methods. 10, 8, p. 747-750 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Spectrum of antimicrobial activity associated with ionic colloidal silver

Morrill, K., May, K., Leek, D., Langland, N., Jeane, L. D., Ventura, J., Skubisz, C., Scherer, S., Lopez, E., Crocker, E., Peters, R., Oertle, J., Nguyen, K., Just, S., Orian, M., Humphrey, M., Payne, D., Jacobs, B., Waters, R. & Langland, J., Mar 1 2013, In : Journal of Alternative and Complementary Medicine. 19, 3, p. 224-231 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Use of a Recombinant Vaccinia Virus Expressing Interferon Gamma for Post-Exposure Protection against Vaccinia and Ectromelia Viruses

Holechek, S. A., Denzler, K. L., Heck, M. C., Schriewer, J., Buller, R. M., Legrand, F. A., Verardi, P. H., Jones, L. A., Yilma, T. & Jacobs, B., Oct 17 2013, In : PloS one. 8, 10, e77879.

Research output: Contribution to journalArticle

6 Scopus citations
2012

In vitro characterization of a nineteenth-century therapy for smallpox

Arndt, W., Mitnik, C., Denzler, K. L., White, S., Waters, R., Jacobs, B., Rochon, Y., Olson, V. A., Damon, I. K. & Langland, J., Mar 9 2012, In : PloS one. 7, 3, e32610.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques

Denzler, K. L., Babas, T., Rippeon, A., Huynh, T., Fukushima, N., Rhodes, L., Silvera, P. M. & Jacobs, B., Dec 6 2011, In : Vaccine. 29, 52, p. 9684-9690 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

Quakkelaar, E. D., Redeker, A., Haddad, E. K., Harari, A., McCaughey, S. M., Duhen, T., Filali-Mouhim, A., Goulet, J. P., Loof, N. M., Ossendorp, F., Perdiguero, B., Heinen, P., Gomez, C. E., Kibler, K., Koelle, D. M., Sékaly, R. P., Sallusto, F., Lanzavecchia, A., Pantaleo, G., Esteban, M. & 3 others, Tartaglia, J., Jacobs, B. & Melief, C. J. M., Feb 28 2011, In : PloS one. 6, 2, e16819.

Research output: Contribution to journalArticle

36 Scopus citations

Improved NYVAC-based vaccine vectors

Kibler, K., Gomez, C. E., Perdiguero, B., Wong, S., Huynh, T., Holechek, S., Arndt, W., Jimenez, V., Gonzalez-Sanz, R., Denzler, K., Haddad, E. K., Wagner, R., Sékaly, R. P., Tartaglia, J., Pantaleo, G., Jacobs, B. & Esteban, M., Nov 9 2011, In : PloS one. 6, 11, e25674.

Research output: Contribution to journalArticle

53 Scopus citations

Innate immune evasion mediated by the Ambystoma tigrinum virus eukaryotic translation initiation factor 2α homologue

Jancovich, J. K. & Jacobs, B., May 1 2011, In : Journal of virology. 85, 10, p. 5061-5069 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

The attenuated NYCBH vaccinia virus deleted for the immune evasion gene, E3L, completely protects mice against heterologous challenge with ectromelia virus

Denzler, K. L., Schriewer, J., Parker, S., Werner, C., Hartzler, H., Hembrador, E., Huynh, T., Holechek, S., Buller, R. M. & Jacobs, B., Dec 6 2011, In : Vaccine. 29, 52, p. 9691-9696 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

The NYCBH vaccinia virus deleted for the innate immune evasion gene, E3L, protects rabbits against lethal challenge by rabbitpox virus

Denzler, K. L., Rice, A. D., MacNeill, A. L., Fukushima, N., Lindsey, S. F., Wallace, G., Burrage, A. M., Smith, A. J., Manning, B. R., Swetnam, D. M., Gray, S. A., Moyer, R. W. & Jacobs, B., Oct 13 2011, In : Vaccine. 29, 44, p. 7659-7669 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Use of a negative selectable marker for rapid selection of recombinant vaccinia virus

White, S. D., Conwell, K., Langland, J. & Jacobs, B., May 1 2011, In : BioTechniques. 50, 5, p. 303-309 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2010

Evidence for multiple recent host species shifts among the ranaviruses (family Iridoviridae)

Jancovich, J. K., Bremont, M., Touchman, J. W. & Jacobs, B., Mar 2010, In : Journal of virology. 84, 6, p. 2636-2647 12 p.

Research output: Contribution to journalArticle

93 Scopus citations

Photonic approach to the selective inactivation of viruses with a near-infrared ultrashort pulsed laser

Tsen, K-T., Tsen, S. W. D., Fu, Q., Lindsay, S., Kibler, K., Jacobs, B., Wu, T. C., Li, Z., Yan, H., Cope, S., Vaiana, S. & Kiang, J. G., May 7 2010, Optical Biopsy VII. 75610W. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7561).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Poxvirus vector-based HIV vaccines

Pantaleo, G., Esteban, M., Jacobs, B. & Tartaglia, J., Sep 1 2010, In : Current Opinion in HIV and AIDS. 5, 5, p. 391-396 6 p.

Research output: Contribution to journalReview article

64 Scopus citations

Regulation of inflammatory gene expression in PBMCs by immunostimulatory botanicals

Denzler, K. L., Waters, R., Jacobs, B., Rochon, Y. & Langland, J., Nov 1 2010, In : PloS one. 5, 9, p. 1-15 15 p., e12561.

Research output: Contribution to journalArticle

24 Scopus citations
2009

OA021-01. Construction and characterization of replication competent attenuated NYVAC-based vectors as potential HIV vaccines

Jacobs, B., Kibler, K., Wong, S., Huynh, T., Holechek, S., Denzler, K., Arndt, W., Parrington, M., Tartaglia, J. & Pantaleo, G., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, p. O13 1742.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

P17-23. Enhanced expression of HIV antigens and improved antigen presentation after infection with replication competent attenuated vaccinia virus in vitro

Quakkelaar, E., Redeker, A., Loof, N., Perdiguero, B., Heinen, P., Nieto, J., Esteban, M., Kibler, K., Jacobs, B., Pantaleo, G. & Melief, C., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, p. P305 1742.

Research output: Contribution to journalComment/debate

Photonic approach to the selective inactivation of viruses with a near-infrared subpicosecond fiber laser

Tsen, K-T., Tsen, S. W. D., Fu, Q., Lindsay, S., Kibler, K., Jacobs, B., Wu, T. C., Karanam, B., Jagu, S., Roden, R. B. S., Hung, C. F., Sankey, O. F., Ramakrishna, B. & Kiang, J. G., Dec 1 2009, In : Journal of biomedical optics. 14, 6, 064042.

Research output: Contribution to journalArticle

24 Scopus citations
37 Scopus citations

Selective inactivation of Human Immunodeficiency Virus with an ultrashort pulsed laser

Tsen, K-T., Tsen, S. W. D., Hung, C. F., Wu, T. C., Kibler, K., Jacobs, B. & Kiang, J. G., 2009, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7175. 717510

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vaccinia virus vaccines: Past, present and future

Jacobs, B., Langland, J., Kibler, K., Denzler, K. L., White, S. D., Holechek, S. A., Wong, S., Huynh, T. & Baskin, C. R., Oct 1 2009, In : Antiviral Research. 84, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

113 Scopus citations
2008
66 Scopus citations