University Administration and Legal Affairs

Research Output 1997 2018

  • 26 Article
  • 2 Conference contribution
2018
7 Citations (Scopus)

Immunization of pigs by DNA prime and recombinant vaccinia virus boost to identify and rank African swine fever virus immunogenic and protective proteins

Jancovich, J. K., Chapman, D., Hansen, D., Robida, M. D., Loskutov, A., Craciunescu, F., Borovkov, A., Kibler, K., Goatley, L., King, K., Netherton, C. L., Taylor, G., Jacobs, B., Sykes, K. & Dixon, L. K., Apr 1 2018, In : Journal of Virology. 92, 8, e02219-17.

Research output: Contribution to journalArticle

African Swine Fever Virus
African swine fever virus
Vaccinia virus
Recombinant DNA
Immunization
2 Citations (Scopus)

Immunogenicity of NYVAC primeprotein boost human immunodeficiency virus type 1 envelope vaccination and simianhuman immunodeficiency virus challenge of nonhuman primates

Saunders, K. O., Santra, S., Parks, R., Yates, N. L., Sutherland, L. L., Scearce, R. M., Balachandran, H., Bradley, T., Goodman, D., Eaton, A., Stanfield-Oakley, S. A., Tartaglia, J., Phogat, S., Pantaleo, G., Esteban, M., Gomez, C. E., Perdiguero, B., Jacobs, B., Kibler, K., Korber, B. & 6 othersMontefiori, D. C., Ferrari, G., Vandergrift, N., Liao, H. X., Tomaras, G. D. & Haynes, B. F., Apr 1 2018, In : Journal of Virology. 92, 8, e02035-17.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
immunosuppression
Macaca
Human immunodeficiency virus 1
Primates
2017

A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles

Meador, L. R., Kessans, S. A., Kilbourne, J., Kibler, K., Pantaleo, G., Roderiguez, M. E., Blattman, J., Jacobs, B. & Leket-Mor, T., Jul 1 2017, In : Virology. 507, p. 242-256 15 p.

Research output: Contribution to journalArticle

Vaccinia virus
Virion
HIV-1
Epitopes
T-Lymphocytes
9 Citations (Scopus)

HIV/AIDS vaccine candidates based on replication-competent recombinant poxvirus NYVAC-C-KC expressing trimeric gp140 and Gag-derived virus-like particles or lacking the viral molecule B19 that inhibits type I interferon activate relevant HIV-1-specific B and T cell immune functions in nonhuman primates

García-Arriaza, J., Perdiguero, B., Heeney, J. L., Seaman, M. S., Montefiori, D. C., Yates, N. L., Tomaras, G. D., Ferrari, G., Foulds, K. E., Roederer, M., Self, S. G., Borate, B., Gottardo, R., Phogat, S., Tartaglia, J., Barnett, S. W., Burke, B., Cristillo, A. D., Weiss, D. E., Lee, C. & 6 othersKibler, K., Jacobs, B., Wagner, R., Ding, S., Pantaleo, G. & Esteban, M., May 1 2017, In : Journal of Virology. 91, 9, e02182-16.

Research output: Contribution to journalArticle

Poxviridae
AIDS Vaccines
Interferon Type I
virus-like particles
interferons
11 Citations (Scopus)

Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

Koehler, H., Cotsmire, S., Langland, J., Kibler, K., Kalman, D., Upton, J. W., Mocarski, E. S. & Jacobs, B., Oct 24 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 43, p. 11506-11511 6 p.

Research output: Contribution to journalArticle

Z-Form DNA
Immune Evasion
Vaccinia virus
Virulence
Cell Death
7 Citations (Scopus)

Superiority in rhesus macaques of targeting HIV-1 Env gp140 to CD40 versus LOX-1 in combination with replication-competent NYVAC-KC for induction of Env-specific antibody and T cell responses

Zurawski, G., Shen, X., Zurawski, S., Tomaras, G. D., Montefiori, D. C., Roederer, M., Ferrari, G., Lacabaratz, C., Klucar, P., Wang, Z., Foulds, K. E., Kao, S. F., Yu, X., Sato, A., Yates, N. L., LaBranche, C., Stanfield-Oakley, S., Kibler, K., Jacobs, B., Salazar, A. & 8 othersSelf, S., Fulp, W., Gottardo, R., Galmin, L., Weiss, D., Cristillo, A., Pantaleo, G. & Levy, Y., May 1 2017, In : Journal of Virology. 91, 9, e01596-16.

Research output: Contribution to journalArticle

dendritic cells
Human immunodeficiency virus 1
Macaca mulatta
Dendritic Cells
T-lymphocytes
2016
2 Citations (Scopus)

A designed “Nested” dimer of cyanovirin-N increases antiviral activity

Woodrum, B. W., Maxwell, J., Allen, D. M., Wilson, J., Krumpe, L. R. H., Bobkov, A. A., Hill, R. B., Kibler, K., O’Keefe, B. R. & Ghirlanda, G., Jun 6 2016, In : Viruses. 8, 6, 158.

Research output: Contribution to journalArticle

Antiviral Agents
Polysaccharides
Binding Sites
HIV
Lectins
7 Citations (Scopus)

Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus

Arndt, W. D., White, S. D., Johnson, B. P., Huynh, T., Liao, J., Harrington, H., Cotsmire, S., Kibler, K., Langland, J. & Jacobs, B., Oct 1 2016, In : Virology. 497, p. 125-135 11 p.

Research output: Contribution to journalArticle

Monkeypox virus
Poxviridae
Vaccinia virus
Virus Diseases
Pharmaceutical Preparations
2 Citations (Scopus)

Selective Photonic Disinfection of Cell Culture Using a Visible Ultrashort Pulsed Laser

Tsen, S. W. D., Kibler, K., Jacobs, B., Fay, J. C., Podolnikova, N., Ugarova, T., Achilefu, S. & Tsen, K-T., May 1 2016, In : IEEE Journal on Selected Topics in Quantum Electronics. 22, 3, 7322185.

Research output: Contribution to journalArticle

ultrashort pulsed lasers
Disinfection
Pulsed lasers
Cell culture
Photonics
8 Citations (Scopus)

Targeting HIV-1 env gp140 to LOX-1 elicits immune responses in rhesus macaques

Zurawski, G., Zurawski, S., Flamar, A. L., Richert, L., Wagner, R., Tomaras, G. D., Montefiori, D. C., Roederer, M., Ferrari, G., Lacabaratz, C., Bonnabau, H., Klucar, P., Wang, Z., Foulds, K. E., Kao, S. F., Yates, N. L., LaBranche, C., Jacobs, B., Kibler, K., Asbach, B. & 11 othersKliche, A., Salazar, A., Reed, S., Self, S., Gottardo, R., Galmin, L., Weiss, D., Cristillo, A., Thiebaut, R., Pantaleo, G. & Levy, Y., Apr 1 2016, In : PLoS One. 11, 4, e0153484.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
Macaca mulatta
immune response
antigen-presenting cells
immunity
2015
17 Citations (Scopus)

Comparison of immunogenicity in rhesus macaques of transmitted-founder, HIV-1 Group M consensus, and trivalent mosaic envelope vaccines formulated as a DNA prime, NYVAC, and envelope protein boost

Hulot, S. L., Korber, B., Giorgi, E. E., Vandergrift, N., Saunders, K. O., Balachandran, H., Mach, L. V., Lifton, M. A., Pantaleo, G., Tartaglia, J., Phogat, S., Jacobs, B., Kibler, K., Perdiguero, B., Gomez, C. E., Esteban, M., Rosati, M., Felber, B. K., Pavlakis, G. N., Parks, R. & 10 othersLloyd, K., Sutherland, L., Scearce, R., Letvin, N. L., Seaman, M. S., Alam, S. M., Montefiori, D., Liao, H. X., Haynes, B. F. & Santra, S., 2015, In : Journal of Virology. 89, 12, p. 6462-6480 19 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
Macaca mulatta
env Gene Products
HIV-1
T-Lymphocyte Epitopes
5 Citations (Scopus)

Evasion of the innate immune type I interferon system by Monkeypox virus

Arndt, W. D., Cotsmire, S., Trainor, K., Harrington, H., Hauns, K., Kibler, K., Huynh, T. P. & Jacobs, B., 2015, In : Journal of Virology. 89, 20, p. 10489-10499 11 p.

Research output: Contribution to journalArticle

Monkeypox virus
Interferon Type I
Vaccinia virus
interferons
Interferon-gamma
21 Citations (Scopus)

Head-to-head comparison of poxvirus NYVAC and ALVAC vectors expressing identical HIV-1 clade C immunogens in prime-boost combination with Env protein in nonhuman primates

García-Arriaza, J., Perdiguero, B., Heeney, J., Seaman, M., Montefiori, D. C., Labranche, C., Yates, N. L., Shen, X., Tomaras, G. D., Ferrari, G., Foulds, K. E., McDermott, A., Kao, S. F., Roederer, M., Hawkins, N., Self, S., Yao, J., Farrell, P., Phogat, S., Tartaglia, J. & 12 othersBarnett, S. W., Burke, B., Cristillo, A., Weiss, D., Lee, C., Kibler, K., Jacobs, B., Asbach, B., Wagner, R., Ding, S., Pantaleo, G. & Esteban, M., 2015, In : Journal of Virology. 89, 16, p. 8525-8539 15 p.

Research output: Contribution to journalArticle

Poxviridae
env Gene Products
Human immunodeficiency virus 1
Primates
HIV-1
15 Citations (Scopus)

Virological and immunological characterization of novel NYVAC-Based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles

Perdiguero, B., Gómez, C. E., Cepeda, V., Sánchez-Sampedro, L., García-Arriaza, J., Mejías-Pérez, E., Jiménez, V., Sánchez, C., Sorzano, C. Ó. S., Oliveros, J. C., Delaloye, J., Roger, T., Calandra, T., Asbach, B., Wagner, R., Kibler, K., Jacobs, B., Pantaleo, G. & Esteban, M., 2015, In : Journal of Virology. 89, 2, p. 970-988 19 p.

Research output: Contribution to journalArticle

AIDS Vaccines
virus-like particles
Virion
vaccines
HIV Antigens
2014
3 Citations (Scopus)

Pathogen reduction in human plasma using an ultrashort pulsed laser

Tsen, S. W. D., Kingsley, D. H., Kibler, K., Jacobs, B., Sizemore, S., Vaiana, S., Anderson, J., Tsen, K-T. & Achilefu, S., Nov 5 2014, In : PLoS One. 9, 11, e111673.

Research output: Contribution to journalArticle

Plasma (human)
Pathogens
Pulsed lasers
Viruses
lasers
2013
9 Citations (Scopus)

Effect of Hepatitis C Infection on HIV-Induced Apoptosis

Laskus, T., Kibler, K., Chmielewski, M., Wilkinson, J., Adair, D., Horban, A., Stańczak, G. & Radkowski, M., Oct 1 2013, In : PLoS One. 8, 10, e75921.

Research output: Contribution to journalArticle

hepatitis C
Hepatitis C virus
Hepatitis C
Viruses
Hepacivirus
2012
6 Citations (Scopus)

A multivalent HIV-1 fusion inhibitor based on small helical foldamers

Guarise, C., Shinde, S., Kibler, K., Ghirlanda, G., Prins, L. J. & Scrimin, P., Jun 10 2012, In : Tetrahedron. 68, 23, p. 4346-4352 7 p.

Research output: Contribution to journalArticle

HIV Fusion Inhibitors
Aminoisobutyric Acids
HIV-1
Assays
Fusion reactions
2011
35 Citations (Scopus)

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

Quakkelaar, E. D., Redeker, A., Haddad, E. K., Harari, A., McCaughey, S. M., Duhen, T., Filali-Mouhim, A., Goulet, J. P., Loof, N. M., Ossendorp, F., Perdiguero, B., Heinen, P., Gomez, C. E., Kibler, K., Koelle, D. M., Sékaly, R. P., Sallusto, F., Lanzavecchia, A., Pantaleo, G., Esteban, M. & 3 othersTartaglia, J., Jacobs, B. & Melief, C. J. M., 2011, In : PLoS One. 6, 2, e16819.

Research output: Contribution to journalArticle

immunostimulation (physiological)
Human Immunodeficiency Virus Proteins
Poxviridae
T-cells
interferons
49 Citations (Scopus)

Improved NYVAC-based vaccine vectors

Kibler, K., Gomez, C. E., Perdiguero, B., Wong, S., Huynh, T., Holechek, S., Arndt, W., Jimenez, V., Gonzalez-Sanz, R., Denzler, K., Haddad, E. K., Wagner, R., Sékaly, R. P., Tartaglia, J., Pantaleo, G., Jacobs, B. & Esteban, M., Nov 9 2011, In : PLoS One. 6, 11, e25674.

Research output: Contribution to journalArticle

vector vaccines
Viruses
Vaccines
viruses
Poxviridae
2010
2 Citations (Scopus)

Photonic approach to the selective inactivation of viruses with a near-infrared ultrashort pulsed laser

Tsen, K-T., Tsen, S. W. D., Fu, Q., Lindsay, S., Kibler, K., Jacobs, B., Wu, T. C., Li, Z., Yan, H., Cope, S., Vaiana, S. & Kiang, J. G., 2010, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7561. 75610W

Research output: Chapter in Book/Report/Conference proceedingConference contribution

ultrashort pulsed lasers
Optics and Photonics
Virus Inactivation
viruses
Pulsed lasers
2009
1 Citation (Scopus)

OA021-01. Construction and characterization of replication competent attenuated NYVAC-based vectors as potential HIV vaccines

Jacobs, B., Kibler, K., Wong, S., Huynh, T., Holechek, S., Denzler, K., Arndt, W., Parrington, M., Tartaglia, J. & Pantaleo, G., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, 1742.

Research output: Contribution to journalArticle

P17-23. Enhanced expression of HIV antigens and improved antigen presentation after infection with replication competent attenuated vaccinia virus in vitro

Quakkelaar, E., Redeker, A., Loof, N., Perdiguero, B., Heinen, P., Nieto, J., Esteban, M., Kibler, K., Jacobs, B., Pantaleo, G. & Melief, C., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, 1742.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Photonic approach to the selective inactivation of viruses with a near-infrared subpicosecond fiber laser

Tsen, K-T., Tsen, S. W. D., Fu, Q., Lindsay, S., Kibler, K., Jacobs, B., Wu, T. C., Karanam, B., Jagu, S., Roden, R. B. S., Hung, C. F., Sankey, O. F., Ramakrishna, B. & Kiang, J. G., 2009, In : Journal of Biomedical Optics. 14, 6, 064042.

Research output: Contribution to journalArticle

Infrared lasers
viruses
Fiber lasers
Viruses
infrared lasers

Selective inactivation of Human Immunodeficiency Virus with an ultrashort pulsed laser

Tsen, K-T., Tsen, S. W. D., Hung, C. F., Wu, T. C., Kibler, K., Jacobs, B. & Kiang, J. G., 2009, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7175. 717510

Research output: Chapter in Book/Report/Conference proceedingConference contribution

ultrashort pulsed lasers
human immunodeficiency virus
Pulsed lasers
Viruses
deactivation
109 Citations (Scopus)

Vaccinia virus vaccines: Past, present and future

Jacobs, B., Langland, J., Kibler, K., Denzler, K. L., White, S. D., Holechek, S. A., Wong, S., Huynh, T. & Baskin, C. R., Oct 2009, In : Antiviral Research. 84, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Vaccinia virus
Vaccines
Smallpox
Viral Genes
Variola virus
2008
30 Citations (Scopus)

Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: Scarification vaccination

Jentarra, G. M., Heck, M. C., Youn, J. W., Kibler, K., Langland, J., Baskin, C. R., Ananieva, O., Chang, Y. & Jacobs, B., Jun 2 2008, In : Vaccine. 26, 23, p. 2860-2872 13 p.

Research output: Contribution to journalArticle

Attenuated Vaccines
Vaccinia virus
live vaccines
Vaccination
vaccination
1997
51 Citations (Scopus)

Complementation of vaccinia virus deleted of the E3L gene by mutants of E3L

Shors, T., Kibler, K., Perkins, K. B., Seidler-Wulff, R., Banaszak, M. P. & Jacobs, B., Dec 22 1997, In : Virology. 239, 2, p. 269-276 8 p.

Research output: Contribution to journalArticle

Vaccinia virus
HeLa Cells
Interferons
Genes
Viruses
165 Citations (Scopus)

Double-stranded RNA is a trigger for apoptosis in vaccinia virus- infected cells

Kibler, K., Shors, T., Perkins, K. B., Zeman, C. C., Banaszak, M. P., Biesterfeldt, J., Langland, J. & Jacobs, B., Mar 1997, In : Journal of Virology. 71, 3, p. 1992-2003 12 p.

Research output: Contribution to journalArticle

Vaccinia virus
Double-Stranded RNA
double-stranded RNA
apoptosis
Apoptosis