Personalized Diagnostics, Virginia G. Piper Center for (PD)

Projects

Projects per year 2007 2009 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2028

• 43 Active
• 179 Finished

Projects per year

Search results

• Active

  Saliva Testing for Botanisol

  Murugan, V.

  INDUSTRY: Domestic Company

  2/1/24 → 5/1/24

  Project: Research project

• Serum biomarkers to predict immune related adverse events and benefit from single agent pembrolizumab therapy in early stage triple negative breast cancer

  Chung, Y., LaBaer, J., Song, L. & Qiu, J.

  HHS: National Institutes of Health (NIH)

  12/14/23 → 11/30/28

  Project: Research project

• Microengineering of Organotypic and Vascularized Tumor Microenvironment Models for Mechanistic Studies of the Metastatic Cascade

  Nikkhah, M. & Park, J.

  National Science Foundation (NSF)

  10/1/23 → 9/30/26

  Project: Research project

  • Environment 100%
  • Application 55%

• Discovering genes that collaborate with mutant TP53 to drive breast cancer aggressiveness

  LaBaer, J. & Park, J.

  Breast Cancer Research Foundation

  10/1/23 → 9/30/24

  Project: Research project

  • Genes 100%

• Planning Study for the Development of Sigma 2 ligands as Analgesics

  Van Horn, W.

  HHS: National Institutes of Health (NIH)

  9/11/23 → 8/31/25

  Project: Research project

  • Analgesics 100%
  • Ligands 82%
  • Horns 79%
  • Magnetic Resonance Spectroscopy 27%
  • Puerto Rico 22%

• Interdisciplinary Systems based Training for Precision Nutrition

  Whisner, C. & Liu, L.

  HHS: National Institutes of Health (NIH)

  9/1/23 → 8/31/28

  Project: Research project

  • Nutrition 100%
  • Artificial intelligence 22%
  • Medical problems 21%
  • Students 19%
  • Health 19%

• Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative, early profiling of pathogen-induced head and neck

  Anderson, K., Song, L., Park, J., LaBaer, J. & Qiu, J.

  HHS: National Institutes of Health (NIH)

  9/1/23 → 8/31/26

  Project: Research project

  • Protein Array Analysis 100%
  • Neck 60%
  • Head 57%
  • High-Throughput Nucleotide Sequencing 16%
  • Antigens 16%

• Interdisciplinary Systems based Training for Precision Nutrition

  Whisner, C. & Liu, L.

  HHS: National Institutes of Health (NIH)

  9/1/23 → 8/31/28

  Project: Research project

  • Nutrition 100%
  • Artificial intelligence 22%
  • Medical problems 21%
  • Students 19%
  • Health 19%

• ICP: High-Throughput and Programmable Protein Synthesis Array System

  Qiu, J. & LaBaer, J.

  INDUSTRY: Domestic Company

  8/14/23 → 8/13/26

  Project: Research project

  • protein microarrays 100%
  • Taiwan 96%
  • protein synthesis 81%
  • nucleic acids 63%
  • technology transfer 54%

• Effect Of Meditation On Healthy Food Consumption

  Murugan, V., Hughner, R. & Grebitus, C.

  USDA: National Institute of Food and Agriculture (NIFA)

  8/1/23 → 7/31/26

  Project: Research project

  • food consumption 100%
  • cortisol 74%
  • food choices 69%
  • nutritional behavior 50%
  • nutritional adequacy 39%

• Southwest EDRN Clinical Validation Center for Head and Neck Cancer

  Murugan, V., Anderson, K. & Chung, Y.

  HHS: National Institutes of Health (NIH)

  8/1/23 → 7/31/28

  Project: Research project

  • Head and Neck Neoplasms 100%
  • Biomarkers 64%
  • Oropharyngeal Neoplasms 48%
  • Early Detection of Cancer 42%
  • Serology 19%

• Personalized NeoAntigenome Analysis (persoNAA) to improve cancer immunotherapy efficacy and reduce adverse events

  Qiu, J., Park, J., LaBaer, J. & Song, L.

  Women and Philanthropy

  7/1/23 → 6/30/24

  Project: Research project

  • Immunotherapy 100%
  • Neoplasms 36%
  • Neoplasm Antigens 23%
  • Immune System 21%
  • Proteins 17%

• MD Anderson Cancer Center EDRN- Clinical Validation Center for Early Detection of Ovarian Cancer with a multiple marker algorithm

  Anderson, K.

  HHS-NIH: National Cancer Institute (NCI)

  6/30/23 → 5/31/28

  Project: Research project

• Induction of autosis to overcome resistance in adoptive cell therapy for solid tumors

  Rahman, M.

  HHS: National Institutes of Health (NIH)

  4/1/23 → 3/31/28

  Project: Research project

  • Cell- and Tissue-Based Therapy 100%
  • Chimeric Antigen Receptors 60%
  • Neoplasms 34%
  • T-Lymphocytes 32%
  • mesothelin 31%

• Comprehensive genomic and immunological analysis to improve personalized management of Lynch syndrome

  LaBaer, J., Qiu, J. & Chung, Y.

  Arizona Biomedical Research Commission

  1/4/23 → 1/3/26

  Project: Research project

  • genomics 100%
  • health services 83%

• Comparative study of human and rat TRPV1 transmembrane domain and its role in thermosensing and agonist activation

  Van Horn, W.

  American Heart Association

  1/1/23 → 12/31/24

  Project: Research project

  • Thermosensing 100%
  • Cations 56%
  • Myocardial Ischemia 9%
  • Temperature 7%
  • Calcium Channels 6%

• Assessing Immune Memory

  Chung, Y., Murugan, V., LaBaer, J., Park, J., Qiu, J. & Magee, M.

  DOD-DARPA: Biological Technologies Office (BTO)

  12/1/22 → 5/1/27

  Project: Research project

  • immunologic memory 100%
  • National Institutes of Health 52%
  • vaccines 34%
  • protein microarrays 10%
  • antibodies 8%

• Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona Populations - Components A & D

  Magee, M., Doane, L., Lim, E., Chung, Y., Scotch, M., Murugan, V. & Cruz, R.

  HHS: Centers for Disease Control and Prevention (CDC)

  9/30/22 → 9/29/27

  Project: Research project

  • Vulnerable Populations 100%
  • Human Influenza 88%
  • Vaccines 72%
  • Vaccination 20%
  • Influenza Vaccines 14%

• COVID-Platform to Assess Influenza and COVID-19 Vaccine Effectiveness in Underserved Arizona Populations

  Magee, M., Murugan, V., Lim, E., Scotch, M., Doane, L., Chung, Y. & Cruz, R.

  HHS: Centers for Disease Control and Prevention (CDC)

  9/30/22 → 9/29/24

  Project: Research project

  • Vulnerable Populations 100%
  • Human Influenza 88%
  • Vaccines 72%
  • Vaccination 20%
  • Influenza Vaccines 14%

• High-throughput immunoproteomics for cancer biomarker discovery

  Qiu, J., LaBaer, J., Chung, Y., Song, L. & Anderson, K.

  HHS: National Institutes of Health (NIH)

  9/1/22 → 8/31/27

  Project: Research project

  • Tumor Biomarkers 100%
  • Biomarkers 66%
  • Ovarian Neoplasms 32%
  • Lung Neoplasms 32%
  • Proteins 21%

• NRT-FW-HTF: Design and Manufacturing of Medical Devices and Implants: Cultivating a Human- Centered Mindset

  Anderson, K., Ladani, L., Andino, J., Rege, K., Razmi, J. & Michael, K.

  National Science Foundation (NSF)

  7/1/22 → 6/30/27

  Project: Research project

  • Medical devices 100%
  • manufacturing 73%
  • event 34%
  • research focus 20%
  • student 19%

• Assay development and implementation to identify vaccine targets and evaluate complex vaccines for bacterial infections

  LaBaer, J., Song, L. & Magee, M.

  DOD: Defense Threat Reduction Agency (DTRA)

  6/23/22 → 6/22/27

  Project: Research project

  • Protein Array Analysis 100%
  • Bacterial Infections 88%
  • Vaccines 71%
  • Yersinia pestis 66%
  • Nucleic Acids 62%

• Understanding human TRPV1 polymodal activation

  Van Horn, W. & Singharoy, A.

  HHS: National Institutes of Health (NIH)

  6/15/22 → 4/30/27

  Project: Research project

  • Ligands 100%
  • Thermosensing 72%
  • Electrophysiology 68%
  • Magnetic Resonance Spectroscopy 68%
  • Protons 61%

• Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions

  Chung, Y. & Borges, C.

  HHS: National Institutes of Health (NIH)

  6/14/22 → 5/31/25

  Project: Research project

  • assays 100%
  • albumins 66%
  • biomedical research 66%
  • absorbance 54%
  • neoplasms 42%

• Aliquot-level visual indicators of biospecimen exposure to thawed conditions

  Chung, Y. & Borges, C.

  HHS: National Institutes of Health (NIH)

  2/2/22 → 1/31/25

  Project: Research project

  • permanganates 100%
  • researchers 57%
  • temperature 56%
  • reaction kinetics 44%
  • freezers 44%

• A zero-cost online biotechnology program for middle and high schools

  Vermaas, W., Hariadi, R. F., Lapinaite, A., Singharoy, A., Anderson, K., Mishra, P. & Hayes, M.

  US Department of Defense (DOD)

  9/15/21 → 9/14/25

  Project: Research project

  • Biotechnology 100%
  • Education 66%
  • Pipelines 35%
  • Molecular dynamics 34%
  • Students 34%

• Discover and Analyze Germline-Somatic Interactions in Cancer

  Liu, L.

  HHS: National Institutes of Health (NIH)

  9/1/21 → 8/31/24

  Project: Research project

  • Genomics 100%
  • Genes 91%
  • Oncology 64%
  • Aberrations 63%
  • Bioinformatics 52%

• Genetics and Genomics of Alternative Polyadenylation and miRNA Regulation in C. e - Renewal - 1

  Mangone, M.

  HHS: National Institutes of Health (NIH)

  8/1/21 → 5/31/25

  Project: Research project

  • Polyadenylation 100%
  • Genomics 79%
  • MicroRNAs 66%
  • 3' Untranslated Regions 35%
  • Protein Isoforms 22%

• Back to ECE Safely with SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income Preschoolers

  Lee, R., Todd, M., Murugan, V. & Oh, H.

  HHS: National Institutes of Health (NIH)

  6/30/21 → 6/29/24

  Project: Research project

  • Hispanic Americans 100%
  • Income 85%
  • Gardens 69%
  • Occupational Groups 45%
  • Child 45%

• Studies in Poxvirus Host Range Genes and Tropism

  Rahman, M.

  HHS: National Institutes of Health (NIH)

  6/23/21 → 5/31/26

  Project: Research project

  • Myxoma virus 100%
  • Viral Tropism 87%
  • Poxviridae 81%
  • Host Specificity 72%
  • Cell Nucleus Active Transport 31%

• Serological Biomarkers for Coccidioidomycosis

  Magee, M., Lake, D., Chung, Y. & LaBaer, J.

  HHS: National Institutes of Health (NIH)

  6/7/21 → 5/31/25

  Project: Research project

  • Coccidioidomycosis 100%
  • Biomarkers 44%
  • Coccidioides 41%
  • Antigens 39%
  • Precipitins 18%

• Unravelling the mechanisms of virus host species jump

  Varsani, A. & Rahman, M.

  HHS: National Institutes of Health (NIH)

  5/26/21 → 4/30/24

  Project: Research project

  • Myxoma virus 100%
  • Poxviridae 81%
  • Yatapoxvirus 60%
  • Monkeypox virus 49%
  • Hares 43%

• Molecular Mechanisms and Regulation Networks of TRPM8

  Van Horn, W.

  HHS: National Institutes of Health (NIH)

  5/1/21 → 2/28/26

  Project: Research project

  • Menthol 100%
  • Cold Temperature 78%
  • Membrane Proteins 72%
  • Mentha 26%
  • Biophysics 23%

• Multiplexed in-solution serological test for SARS-CoV-2, human coronaviruses and other respiratory pathogens

  Qiu, J., Murugan, V., Chung, Y., LaBaer, J. & Park, J.

  HHS: National Institutes of Health (NIH)

  10/1/20 → 9/30/25

  Project: Research project

  • SARS Virus 100%
  • Coronavirus 85%
  • Serologic Tests 74%
  • Validation Studies 40%
  • Contracts 36%

• NIGMS National and Regional Resources - DNASU

  Park, J., Murugan, V., Magee, M. & LaBaer, J.

  HHS: National Institutes of Health (NIH)

  8/15/20 → 7/31/25

  Project: Research project

  • plasmids 100%
  • clones 72%
  • protein structure 30%
  • funding 26%
  • researchers 24%

• Viral inhibition of cell death in host immune responses

  Rahman, M.

  HHS: National Institutes of Health (NIH)

  6/22/20 → 5/31/24

  Project: Research project

  • Cell Death 100%
  • Viruses 87%
  • Cowpox virus 42%
  • Vaccinia virus 31%
  • Ubiquitination 28%

• Investigating the Influences of Sleep-Wake Patterns and Gut Microbiome Developmentin Infancy on Rapid Weight Gain, an Early Risk Factor for Obesity

  Liu, L., Krajmalnik-Brown, R., Whisner, C., Petrov, M. & Reifsnider, E.

  HHS: National Institutes of Health (NIH)

  2/1/20 → 1/31/25

  Project: Research project

  • Gastrointestinal Microbiome 100%
  • Weight Gain 92%
  • Sleep 78%
  • Obesity 70%
  • Pediatric Obesity 12%

• Rapid Low-Cost Paper-based Biodosimetry that reveals individual organ injuries

  Park, J., LaBaer, J. & Murugan, V.

  HHS: National Institutes of Health (NIH)

  2/1/20 → 1/31/25

  Project: Research project

  • Radiation 100%
  • Costs and Cost Analysis 82%
  • Biomarkers 64%
  • Wounds and Injuries 64%
  • Point-of-Care Systems 62%

• Rapid Point of Care Detection of HPV-Associated Malignancies - Renewal - 1-UH3 Phase

  Anderson, K. & Blain Christen, J.

  HHS: National Institutes of Health (NIH)

  9/1/19 → 8/31/24

  Project: Research project

  • Point-of-Care Systems 100%
  • Fluorescence 46%
  • Smartphone 30%
  • Human papillomavirus 16 29%
  • Neoplasms 28%

• Collaborative Research: Role of DNA sequence and deformability on lesion recognit

  Levitus, M. & Van Horn, W.

  National Science Foundation (NSF)

  7/15/19 → 6/30/24

  Project: Research project

  • cooperative research 100%
  • DNA repair 77%
  • uracil-DNA glycosylase 68%
  • college students 50%
  • thymine-DNA glycosylase 49%

• Investigating the Biophysical and Biochemical Influences of Stromal Cells on Anti-Cancer Drug Resistance within Bioengineered Tumor Microenvironment Models

  Nikkhah, M. & Park, J.

  National Science Foundation (NSF)

  7/1/19 → 6/30/24

  Project: Research project

  • Tumor Microenvironment 100%
  • Stromal Cells 96%
  • Drug Resistance 88%
  • Neoplasms 31%
  • Microfluidics 10%

• IIBR Informatics: Integrating codon evolution and sequence-assembly error models into multiple sequence alignment

  Cartwright, R.

  National Science Foundation (NSF)

  6/15/19 → 5/31/24

  Project: Research project

  • software 100%
  • artifact 76%
  • instructor 64%
  • coding 51%
  • best practice 46%

• Leveraging Bio-Cultural Mechanisms to Maximize the Impact of Multi-Level Preventable Disease Interventions with Southwest Populations

  Marsiglia, F., Kulis, S., Wolfersteig, W., Shaibi, G., Rankin, L., Vega Lopez, S., Jager, J., Ayers, S., Murugan, V., Oh, H. & Liu, L.

  HHS-NIH: National Center on Minority Health and Health Disparities (NIMHD)

  9/22/17 → 6/30/24

  Project: Research project

  • director 100%
  • health 92%
  • infrastructure 82%
  • career 75%
  • minority 69%
• Finished

  Discovering genes that collaborate with mutant TP53 to drive breast cancer aggressiveness

  Park, J. & LaBaer, J.

  Breast Cancer Research Foundation

  10/1/22 → 9/30/23

  Project: Research project

  • Drive 100%
  • Breast Neoplasms 61%
  • Mutant Proteins 57%
  • Mutation 54%
  • Guide RNA 40%

• High-end MALDI Time of Flight Mass Spectrometer for Bioanalysis

  Velazquez, R., Fromme, P., Moore, G., Mills, J., Moore, A., Borges, C., Stephanopoulos, N., Vaiana, S., Sandrin, T., Ros, A., Mastroeni, D., Hecht, S. & Long, T.

  HHS: National Institutes of Health (NIH)

  8/15/22 → 8/14/23

  Project: Research project

  • Mass spectrometers 100%
  • Ionization 91%
  • Mass spectrometry 90%
  • Desorption 80%
  • Lasers 53%

• Biomarkers for differential diagnosis, targeted management and prognostication of post-viral, inflammatory, and neurodegenerative smell loss

  Magee, M.

  ASU: Mayo Seed Grant

  7/1/22 → 6/30/23

  Project: Research project

  • Smell 100%
  • Differential Diagnosis 65%
  • Biomarkers 55%
  • Piper 13%
  • Neurodegenerative Diseases 13%

• Comprehensive genomic and immunological analysis to improve personalized management of Lynch syndrome

  LaBaer, J., Qiu, J., Song, L. & Chung, Y.

  ASU: Mayo Seed Grant

  7/1/22 → 12/31/23

  Project: Research project

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • Colorectal Neoplasms 60%
  • Neoplasms 20%
  • Antibodies 15%
  • Antibody Formation 12%

• Tailoring perianal Crohns Disease management through molecular fingerprinting: Developing more personalized and effective therapeutic strategies.

  Qiu, J., Chung, Y., LaBaer, J. & Park, J.

  Mayo Clinic Rochester

  6/15/22 → 12/14/23

  Project: Research project

  • Disease Management 100%
  • Crohn Disease 96%
  • Protein Array Analysis 42%
  • Data Analysis 25%
  • Antibodies 18%

• Discovering genes that collaborate with mutant TP53 to drive breast cancer aggres - Renewal - 1

  LaBaer, J. & Park, J.

  Breast Cancer Research Foundation

  10/1/21 → 9/30/22

  Project: Research project

  • Breast Neoplasms 100%
  • Mutation 87%
  • Genes 63%
  • Cell Movement 42%
  • Pharmaceutical Preparations 32%

• Parasite serological profiling of patients with advanced gastric preneoplastic lesions

  LaBaer, J.

  HHS: National Institutes of Health (NIH)

  9/30/21 → 9/29/22

  Project: Research project

  • contractors 100%
  • stomach 63%
  • lesions (animal) 62%
  • parasites 53%
  • stomach neoplasms 27%