Biological and Health Systems Engineering, School of (IAFSE-BHSE)

Projects

Projects per year 1996 2005 2010 2011 2014 2015 2016 2017 2018 2019 2020 2021 2022 2027

• 59 Active
• 297 Finished

Projects per year

Search results

• Active

  Coordination of human grasp and manipulation forces

  Santello, M.

  HHS: National Institutes of Health (NIH)

  2/6/23 → 1/31/25

  Project: Research project

• Metabolic regulation of human cortical development & disease

  Andrews, M.

  Arizona Biomedical Research Commission

  1/4/23 → 1/3/26

  Project: Research project

  • Human Development 100%

• Magnetic Resonance Imaging of Amino Acid Uptake and Metabolism in Primary Brain Tumors

  Beeman, S.

  Arizona Biomedical Research Commission

  1/4/23 → 1/4/26

  Project: Research project

  • Brain Neoplasms 100%
  • Amino Acids 75%
  • Magnetic Resonance Imaging 71%

• Investigating the protective mechanisms of APOE2

  Brafman, D.

  Alzheimer's Association

  1/1/23 → 12/31/26

  Project: Research project

  • Protein Isoforms 100%
  • Alleles 72%
  • Amyloid 70%
  • Induced Pluripotent Stem Cells 56%
  • Pathology 47%

• Portable Neurostimulation System for Chronic Migraine Pain

  Muthuswamy, J.

  Flinn Foundation

  1/1/23 → 12/31/23

  Project: Research project

  • Migraine Disorders 100%
  • Chronic Pain 90%

• AChMRNS Nanosensors for Chemical Imaging of Acetylcholine Using MRI

  Clark (SBHSE), H.

  HHS: National Institutes of Health (NIH)

  12/1/22 → 6/30/23

  Project: Research project

  • Acetylcholine 100%

• EMIT - Male Contraceptive

  Weaver, J.

  VentureWell

  12/1/22 → 8/31/23

  Project: Research project

  • Male Contraceptive Agents 100%
  • Organized Financing 75%
  • Financial Management 38%
  • Organizations 28%
  • Budgets 17%

• Neuromodulation by EM Induced Hypersound

  Muthuswamy, J.

  National Science Foundation (NSF)

  10/1/22 → 6/30/23

  Project: Research project

  • nerve tissue 100%
  • microwave radiation 78%
  • rodents 50%
  • rats 38%
  • antennae 33%

• US-ASEAN Science, Technology and Innovation Cooperation (STIC) Program

  Goss, J.

  DOS: Bureau of East Asian and Pacific Affairs (EAP)

  9/26/22 → 9/30/25

  Project: Research project

  • ASEAN 100%
  • innovation 56%
  • member state 33%
  • grant 24%
  • industry 16%

• HDO Imaging as a Quantitative Marker of Cerebral Glucose Oxidation

  Kodibagkar, V.

  HHS: National Institutes of Health (NIH)

  9/1/22 → 5/31/26

  Project: Research project

  • Glucose 100%
  • Deoxyglucose 71%
  • Positron-Emission Tomography 41%
  • Signal-To-Noise Ratio 30%
  • Magnetic Resonance Spectroscopy 29%

• Optical imaging of size, charge, mobility and binding of single proteins

  Wang, S.

  HHS: National Institutes of Health (NIH)

  9/1/22 → 8/31/26

  Project: Research project

  • Optical Imaging 100%
  • Carrier Proteins 77%
  • Proteins 33%
  • Technology 29%
  • Single Molecule Imaging 10%

• Developing vaccines for immunological defense from traumatic brain injury

  Stabenfeldt, S. & Acharya, A.

  DOD-ARMY: Army Medical Research Acquisition Activity (USAMRAA)

  8/15/22 → 8/14/24

  Project: Research project

  • Traumatic Brain Injury 100%
  • Vaccines 76%
  • Proteolipids 17%
  • Encephalitis 13%
  • Glycolysis 12%

• Longitudinal electrophysiological studies of DBS in patients with chronic pain

  Greger, B.

  National Science Foundation (NSF)

  8/5/22 → 6/30/23

  Project: Research project

  • Chronic Pain 100%
  • Longitudinal Studies 91%

• Developing Fall Detection Tools for Usage in Senior Living Facilities

  Lockhart, T.

  National Science Foundation (NSF)

  8/5/22 → 6/30/23

  Project: Research project

  • Accidents 100%
  • Nursing 78%
  • Sleep 66%
  • Risk assessment 61%
  • Muscle 58%

• BD FACSymphony S6 cell sorter

  Brafman, D.

  HHS: National Institutes of Health (NIH)

  8/1/22 → 7/31/23

  Project: Research project

  • S 6 100%
  • Flow Cytometry 50%
  • Color 15%
  • Lasers 15%
  • Research Personnel 13%

• Establishing Genotype-to-Phenotype Relationships Between Alzheimers Related BIN1 Variants

  Brafman, D.

  HHS: National Institutes of Health (NIH)

  8/1/22 → 7/31/24

  Project: Research project

  • Genotype 100%
  • Phenotype 84%
  • Serum Amyloid A Protein 61%
  • Bioengineering 60%
  • Gene Editing 57%

• Arizona Alzheimer's Consortium (AAC) FY23 Match

  Ofori, E., Wang, Y., Mastroeni, D., Youngstedt, S., Coon, D., Yeom, D. J., Bimonte-Nelson, H., Sierks, M., Schaefer, S., Stabenfeldt, S., Brafman, D., Klein-Seetharaman, J., Shishegar, N., Readhead, B., Maxfield, M. & Verpeut, J.

  Arizona Department of Health Services

  7/1/22 → 6/30/23

  Project: Research project

• IUCRC Phase II ASU: Building Reliable Advances and Innovations in Neurotechnology (BRAIN)

  Santello, M.

  National Science Foundation (NSF)

  4/19/22 → 6/30/27

  Project: Research project

  • Technology 100%
  • Scanning Transmission Electron Microscopy 50%
  • Students 44%
  • Hispanic Americans 36%
  • Industry 35%

• Target to trial rapid immunotherapy development against West Nile virus

  Bartelle, B.

  Flinn Foundation

  4/15/22 → 10/14/23

  Project: Research project

  • West Nile virus 100%
  • Immunotherapy 67%
  • Biological Therapy 60%
  • Costs and Cost Analysis 47%
  • Containment of Biohazards 35%

• Biomarkers for the Clinical Diagnosis of ALS Patients

  Smith, B.

  Flinn Foundation

  4/15/22 → 10/15/23

  Project: Research project

  • Amyotrophic Lateral Sclerosis 100%
  • Biomarkers 60%
  • Neurodegenerative Diseases 11%
  • Economics 10%
  • Pathology 8%

• Defining cellular states of quiescence in human brain tumors

  Plaisier, C.

  HHS: National Institutes of Health (NIH)

  4/1/22 → 11/30/23

  Project: Research project

  • Tumors 100%
  • Brain 80%
  • Gene expression 35%
  • Cells 31%
  • Genes 31%

• Higher Education Partnership Initiative (HEPI)

  Goss, J. & Danielson, S.

  US Agency for International Development (USAID)

  2/24/22 → 2/23/27

  Project: Research project

  • innovation 100%
  • industry 90%
  • Vietnam 77%
  • accreditation 71%
  • education 71%

• Non-invasive, longitudinal assessment of adipocyte size during the pathogenesis of type 2 diabetes

  Beeman, S.

  HHS: National Institutes of Health (NIH)

  2/15/22 → 1/31/24

  Project: Research project

  • Adipocytes 100%
  • Insulin Resistance 80%
  • Type 2 Diabetes Mellitus 78%
  • Hypoxia 48%
  • Obesity 34%

• Elucidating the protective effects of the KL-VS variant using isogenic hiPSCs

  Brafman, D.

  HHS: National Institutes of Health (NIH)

  2/15/22 → 1/31/24

  Project: Research project

  • Human Uses 100%

• Improving Brain Organoid Models by Mediating Metabolic Dysregulation

  Andrews, M.

  HHS: National Institutes of Health (NIH)

  1/18/22 → 12/31/24

  Project: Research project

  • Organoids 100%
  • Brain 37%
  • Physiological Stress 10%
  • Transplantation 6%
  • RNA Sequence Analysis 5%

• Modular Platform for Combinatorial Epigenome Manipulation

  Cheng, A.

  HHS: National Institutes of Health (NIH)

  1/1/22 → 12/31/23

  Project: Research project

  • epigenetics 100%
  • precision medicine 27%
  • genomics 26%
  • phenotype 16%
  • histone code 10%

• Collaborative Research: CIF: Medium: New Methods for Learning on Hypergraphs for Single-Cell Chromatin Data Analysis

  Cheng, A.

  National Science Foundation (NSF)

  1/1/22 → 6/30/24

  Project: Research project

  • Genomics 100%
  • Machine learning 70%
  • Cells 46%
  • Data acquisition 40%
  • Methylation 38%

• Using an Online Video Game to Predict Functional and Cognitive Decline within the MindCrowd Electronic Cohort

  Schaefer, S.

  HHS: National Institutes of Health (NIH)

  1/1/22 → 12/31/24

  Project: Research project

  • Video Games 100%
  • Cognitive Dysfunction 62%
  • Alzheimer Disease 58%
  • Psychological Practice 56%
  • Cohort Effect 17%

• Using hiPSCs to investigate the protective mechanisms of the ApoEch mutation

  Brafman, D.

  HHS: National Institutes of Health (NIH)

  9/30/21 → 8/31/23

  Project: Research project

  • Apolipoproteins E 100%
  • Mutation 65%
  • Gene Editing 57%
  • Apolipoprotein E3 34%
  • Alleles 34%

• Model-guided design of RNA stabilizing elements for improved coronavirus diagnostics

  Wang, X.

  HHS: National Institutes of Health (NIH)

  9/17/21 → 9/16/25

  Project: Research project

  • Coronavirus 100%
  • RNA Stability 61%
  • RNA 55%
  • Ribonucleases 31%
  • Technology 18%

• Optimizing macroencapsulation devices for islet transplantation via magnetic resonance oximetry

  Kodibagkar, V. & Weaver, J.

  HHS: National Institutes of Health (NIH)

  9/16/21 → 6/30/25

  Project: Research project

  • Islets of Langerhans Transplantation 100%
  • Oximetry 93%
  • Magnetic Resonance Spectroscopy 65%
  • Equipment and Supplies 46%
  • Equipment Design 19%

• Elucidating the Role of Perivascular Niche in Glioblastoma Invasion and Therapeutic Resistance at Single Cell Resolution using Biomimetic Tumor Microenvironment Models

  Plaisier, C. & Nikkhah, M.

  HHS: National Institutes of Health (NIH)

  9/15/21 → 7/31/26

  Project: Research project

  • Biomimetics 100%
  • Tumor Microenvironment 82%
  • Glioblastoma 78%
  • Glioma 73%
  • Stem Cells 58%

• Immunosuppression-free transplantation through placental mimicry

  Weaver, J.

  HHS: National Institutes of Health (NIH)

  9/14/21 → 8/31/24

  Project: Research project

  • immunosuppression 100%
  • placenta 86%
  • trophoblast 69%
  • cell transplantation 41%
  • immunology 35%

• Mechanistic role of vascular dysfunction in TBI-mediated cognitive dysfunction

  Nikkhah, M.

  US Department of Veterans Affairs (VA)

  9/7/21 → 9/6/25

  Project: Research project

  • Contracts 100%
  • Cognitive Dysfunction 70%
  • Small Business 70%
  • Blood Vessels 50%
  • Tungsten 48%

• Discovery and delivery platform making small RNAs a viable therapeutic option for mesothelioma

  Plaisier, C.

  DOD-ARMY: Army Medical Research Acquisition Activity (USAMRAA)

  9/1/21 → 8/31/24

  Project: Research project

  • Mesothelioma 100%
  • RNA 58%
  • Cell Line 29%
  • Pemetrexed 27%
  • Cisplatin 21%

• Electrical Spectral Imaging Using Magnetic Resonance Methods

  Sohn, S. & Sadleir, R.

  HHS: National Institutes of Health (NIH)

  9/1/21 → 6/30/23

  Project: Research project

  • magnetic resonance 100%
  • tumors 59%
  • brain 59%
  • electrical properties 57%
  • tensors 46%

• CAREER: Reconfiguring Life: Care and control in bioengineering

  Frow, E.

  National Science Foundation (NSF)

  9/1/21 → 8/31/26

  Project: Research project

  • governance 100%
  • technology studies 72%
  • biology 65%
  • science studies 64%
  • engineering 55%

• Collaborative Research: Toward lifelike synthetic cells via engineered control of DNA replication

  Frow, E.

  National Science Foundation (NSF)

  8/15/21 → 7/31/24

  Project: Research project

  • Artificial Cells 100%
  • DNA Replication 71%
  • Plasmids 57%
  • Replication Origin 24%
  • Synthetic Biology 18%

• Linking TBI secondary injuries to FTLD- and ALS-like neurodegeneration

  Stabenfeldt, S.

  HHS: National Institutes of Health (NIH)

  8/15/21 → 7/31/23

  Project: Research project

  • Frontotemporal Dementia With Motor Neuron Disease 100%
  • Traumatic Brain Injury 63%
  • Wounds and Injuries 31%
  • Neurodegenerative Diseases 25%
  • Rhombencephalon 18%

• Multi-Scale Engineering of Heterogeneity in the Host-Aware Synthetic Gene Circuits

  Tian, X.

  HHS: National Institutes of Health (NIH)

  8/15/21 → 7/31/26

  Project: Research project

  • Genes 100%
  • Networks (circuits) 57%
  • Fluorescence 5%
  • Gene expression 5%
  • Microfluidics 5%

• Toward use of the synergy-based SoftHand Pro for activities of daily living by transradial amputees: A multi-site clinical trial

  Santello, M.

  HHS: National Institutes of Health (NIH)

  8/12/21 → 7/31/26

  Project: Research project

  • Prosthetics 100%
  • End effectors 16%
  • Functional assessment 12%
  • Robotics 11%
  • Feedback 9%

• One-shot morphologic, hemodynamic and metabolic MR imaging of brain tumors

  Kodibagkar, V.

  HHS: National Institutes of Health (NIH)

  7/5/21 → 6/30/26

  Project: Research project

  • Brain Neoplasms 100%
  • Hypoxia 84%
  • Hemodynamics 79%
  • TH 302 18%
  • Contrast Media 17%

• Craftwork as Soulwork: Sanctifying Scientific Practice among GeneticsResearchers

  Braden, B. B., Stabenfeldt, S., Robert, J., Helms Tillery, S. & Bennett, G.

  John Templeton Foundation

  7/1/21 → 6/30/23

  Project: Research project

  • Craftwork 100%
  • Scientific Practice 72%
  • Spiritual Formation 38%
  • Religion 13%
  • Monastery 13%

• Addressing socioeconomic disparities in post-stroke disability through the development of an accessible, new tool

  Honeycutt, C.

  HHS: National Institutes of Health (NIH)

  4/26/21 → 3/31/24

  Project: Research project

  • Stroke 100%
  • Rehabilitation 76%
  • Social Class 58%
  • Upper Extremity 35%
  • Therapeutics 23%

• Exploiting sex-dependent brain injury response for nanoparticle therapeutics - Resubmission - 1

  Bimonte-Nelson, H., Newbern, J., Plaisier, C. & Stabenfeldt, S.

  HHS: National Institutes of Health (NIH)

  1/1/21 → 11/30/25

  Project: Research project

  • Brain Injuries 100%
  • Nanoparticles 91%
  • Traumatic Brain Injury 78%
  • Gonadal Steroid Hormones 43%
  • Pharmaceutical Preparations 29%

• Addressing stroke outcome inequities through the development of an accessible, low cost rehabilitation intervention

  Honeycutt, C.

  American Heart Association

  1/1/21 → 12/31/23

  Project: Research project

  • Rehabilitation 100%
  • Stroke 88%
  • Costs and Cost Analysis 80%
  • Social Class 51%
  • Vulnerable Populations 22%

• Neuroimmune Programming with Engineered Zika Virus

  Bartelle, B.

  1907 Research

  12/15/20 → 6/12/23

  Project: Research project

  • Zika Virus 100%
  • Microglia 42%
  • Genome 11%
  • Bioengineering 11%
  • Autophagy 8%

• CAREER: Communication through Interaction: Intent Inference and Signaling to Facilitate Human Learning in Rehabilitation Robots

  Zhang, W. & Santello, M.

  National Science Foundation (NSF)

  9/1/20 → 8/31/25

  Project: Research project

  • Patient rehabilitation 100%
  • Robots 68%
  • Human robot interaction 61%
  • Communication 53%
  • Intelligent robots 15%

• Electromechanical Interaction of Gold Nanomaterials with Human Cardiac Cells - Resubmission - 1

  Westerhoff, P., Perreault, F. & Nikkhah, M.

  National Science Foundation (NSF)

  7/1/20 → 6/30/24

  Project: Research project

  • Nanostructures 100%
  • Gold 87%
  • Nanotechnology 16%
  • Tissue Engineering 13%
  • Regenerative Medicine 9%

• CAREER: Multi-Parametric Electrophysiology for High-Resolution Deep Brain Circuit Analysis

  Smith, B.

  National Science Foundation (NSF)

  1/1/20 → 12/31/24

  Project: Research project

  • Electrophysiology 100%
  • Acoustics 59%
  • Electrodes 44%
  • Brain 43%
  • Opioid-Related Disorders 27%