BI: Bioenergetics, Center for (BE)

Research Output 2006 2019

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2015
2 Citations (Scopus)

Fluorescent CD4 probe for potential HIV-1 gp120 protein detection

Wang, Z., Talukder, P., Hecht, S. & Chen, S., Mar 15 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 6, p. 1182-1185 4 p.

Research output: Contribution to journalArticle

Fluorescent Dyes
Tryptophan
HIV-1
Fluorescence
Evans Blue
14 Citations (Scopus)

Main source of microwave loss in transition-metal-doped Ba(Zn1/3Ta2/3)O3and Ba(Zn1/3Nb2/3)O3at cryogenic temperatures

Zhang, S., Devonport, A. & Newman, N., 2015, In : Journal of the American Ceramic Society. 98, 4, p. 1188-1194 7 p.

Research output: Contribution to journalArticle

Cryogenics
Transition metals
Microwaves
Paramagnetic resonance
Magnetic fields
13 Citations (Scopus)

Nanoporous delafossite CuAlO2 from inorganic/polymer double gels: A desirable high-surface-area p-type transparent electrode material

Das, B., Renaud, A., Volosin, A. M., Yu, L., Newman, N. & Seo, D., Feb 2 2015, In : Inorganic Chemistry. 54, 3, p. 1100-1108 9 p.

Research output: Contribution to journalArticle

Inorganic polymers
electrode materials
crystallinity
photoelectrochemical devices
Gels
10 Citations (Scopus)
Mitochondria
Amyloid
Epigenomics
Antioxidants
Maintenance
27 Citations (Scopus)

Protein Synthesis with Ribosomes Selected for the Incorporation of β-Amino Acids

Maini, R., Chowdhury, S. R., Dedkova, L., Roy, B., Daskalova, S. M., Paul, R., Chen, S. & Hecht, S., Jun 16 2015, In : Biochemistry. 54, 23, p. 3694-3706 13 p.

Research output: Contribution to journalArticle

Puromycin
Ribosomes
Alanine
Tetrahydrofolate Dehydrogenase
Amino Acids
264 Citations (Scopus)

Redesigning photosynthesis to sustainably meet global food and bioenergy demand

Ort, D. R., Merchant, S. S., Alric, J., Barkan, A., Blankenship, R. E., Bock, R., Croce, R., Hanson, M. R., Hibberd, J. M., Long, S. P., Moore, T., Moroney, J., Niyogi, K. K., Parry, M. A. J., Peralta-Yahya, P. P., Prince, R. C., Redding, K., Spalding, M. H., Van Wijk, K. J., Vermaas, W. & 5 others, Von Caemmerer, S., Weber, A. P. M., Yeates, T. O., Yuan, J. S. & Zhu, X. G., Jul 14 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 28, p. 8529-8536 8 p.

Research output: Contribution to journalArticle

Photosynthesis
Synthetic Biology
Food
Biofuels
Population Growth
25 Citations (Scopus)

Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro

Maini, R., Dedkova, L., Paul, R., Madathil, M. M., Chowdhury, S. R., Chen, S. & Hecht, S., Sep 9 2015, In : Journal of the American Chemical Society. 137, 35, p. 11206-11209 4 p.

Research output: Contribution to journalArticle

Dipeptides
Ribosomes
Proteins
Puromycin
Clone Cells
37 Citations (Scopus)

Structural features facilitating tumor cell targeting and internalization by bleomycin and its disaccharide

Yu, Z., Paul, R., Bhattacharya, C., Bozeman, T. C., Rishel, M. J. & Hecht, S., May 19 2015, In : Biochemistry. 54, 19, p. 3100-3109 10 p.

Research output: Contribution to journalArticle

Disaccharides
Bleomycin
Tumors
Cells
Neoplasms
9 Citations (Scopus)

Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein

Roy Chowdhury, S., Maini, R., Dedkova, L. & Hecht, S., May 8 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 21, p. 4715-4718 4 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Oxazoles
Thiazoles
Fluorophores
2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide
15 Citations (Scopus)
Biomarkers
Research
Precision Medicine
Practice Guidelines
Private Sector
2014
14 Citations (Scopus)

A short DNA sequence confers strong bleomycin binding to hairpin DNAs

Tang, C., Paul, A., Alam, M. P., Roy, B., Wilson, W. D. & Hecht, S., Sep 4 2014, In : Journal of the American Chemical Society. 136, 39, p. 13715-13726 12 p.

Research output: Contribution to journalArticle

DNA sequences
Bleomycin
DNA
DNA Cleavage
Gene Library
13 Citations (Scopus)

Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases

Alam, M. P., Khdour, O., Arce, P. M., Chen, Y., Roy, B., Johnson, W. G., Dey, S. & Hecht, S., Sep 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 17, p. 4935-4947 13 p.

Research output: Contribution to journalArticle

Mitochondrial Diseases
Neurodegenerative Diseases
Antioxidants
Mitochondrial Membrane Potential
Liver Microsomes
19 Citations (Scopus)

Design and expression of a short peptide as an HIV detection probe

Lines, J. A., Yu, Z., Dedkova, L. & Chen, S., Jan 3 2014, In : Biochemical and Biophysical Research Communications. 443, 1, p. 308-312 5 p.

Research output: Contribution to journalArticle

HIV
Peptides
Proteins
Escherichia coli
HIV Infections
8 Citations (Scopus)

DNA methylation reduces binding and cleavage by bleomycin

Roy, B., Tang, C., Alam, M. P. & Hecht, S., Sep 30 2014, In : Biochemistry. 53, 38, p. 6103-6112 10 p.

Research output: Contribution to journalArticle

Bleomycin
DNA Methylation
DNA Cleavage
Methylation
DNA
15 Citations (Scopus)

Efficient asymmetric synthesis of Tryptophan Analogues having useful Photophysical properties

Talukder, P., Chen, S., Arce, P. M. & Hecht, S., 2014, In : Organic Letters. 16, 2, p. 556-559 4 p.

Research output: Contribution to journalArticle

tryptophan
Tryptophan
analogs
Tetrahydrofolate Dehydrogenase
probes

Electromagnetic bandgap resonators synthesized using ceramic injection molding

Henderson, R., Tang, Z., Liu, S., Petras, M., Aberle, J. & Newman, N., Feb 2014, In : Microwave and Optical Technology Letters. 56, 2, p. 371-375 5 p.

Research output: Contribution to journalArticle

injection molding
Injection molding
Resonators
Energy gap
resonators
injection molding
Injection molding
Resonators
Energy gap
resonators

Erratum: Switching at small magnetic fields in Josephson junctions fabricated with ferromagnetic barrier layers [Appl. Phys. Lett. 104, 022602 (2014)]

Abd El Qader, M., Singh, R., Galvin, S. N., Yu, L., Rowell, J. M. & Newman, N., 2014, In : Applied Physics Letters. 104, 9, 099903.

Research output: Contribution to journalArticle

barrier layers
Josephson junctions
magnetic fields
12 Citations (Scopus)

Fabrication of highly spin-polarized Co2FeAl 0.5Si0.5 thin-films

Vahidi, M., Gifford, J. A., Zhang, S. K., Krishnamurthy, S., Yu, Z. G., Yu, L., Huang, M., Youngbull, C., Chen, T. & Newman, N., 2014, In : APL Materials. 2, 4, 046108.

Research output: Contribution to journalArticle

Spin polarization
Fabrication
Thin films
Epitaxial films
Substrates
1 Citation (Scopus)

Growth and characterization of epitaxial Ba(Co,Zn)1/3Nb 2/3O3 thin films

Li, Y., Kopas, C., Huang, M., Bunish, K. & Newman, N., 2014, In : Journal of Crystal Growth. 387, p. 81-85 5 p.

Research output: Contribution to journalArticle

Thin films
Substrates
thin films
Surface roughness
Dielectric films
18 Citations (Scopus)

Hairpin DNA sequences bound strongly by bleomycin exhibit enhanced double-strand cleavage

Roy, B. & Hecht, S., Mar 19 2014, In : Journal of the American Chemical Society. 136, 11, p. 4382-4393 12 p.

Research output: Contribution to journalArticle

DNA sequences
Bleomycin
DNA
Libraries
Base Pairing
1 Citation (Scopus)

High energy and spatial resolution EELS band gap measurements using a nion monochromated cold field emission HERMES dedicated STEM

Carpenter, R., Xie, H., Lehner, S., Aoki, T., Mardinly, J., Vahidi, M., Newman, N. & Ponce, F., Aug 1 2014, In : Microscopy and Microanalysis. 20, 3, p. 70-71 2 p.

Research output: Contribution to journalArticle

Electron energy loss spectroscopy
Field emission
field emission
Energy gap
spatial resolution
23 Citations (Scopus)

Modified bleomycin disaccharides exhibiting improved tumor cell targeting

Madathil, M. M., Bhattacharya, C., Yu, Z., Paul, R., Rishel, M. J. & Hecht, S., Nov 4 2014, In : Biochemistry. 53, 43, p. 6800-6810 11 p.

Research output: Contribution to journalArticle

Disaccharides
Bleomycin
Tumors
Cells
Neoplasms
6 Citations (Scopus)

Probing of CD4 binding pocket of HIV-1 gp120 glycoprotein using unnatural phenylalanine analogues

Yu, X., Talukder, P., Bhattacharya, C., Fahmi, N. E., Lines, J. A., Dedkova, L., LaBaer, J., Hecht, S. & Chen, S., Dec 15 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 24, p. 5699-5703 5 p.

Research output: Contribution to journalArticle

Phenylalanine
HIV-1
Glycoproteins
HIV
Conformations
47 Citations (Scopus)

Switching at small magnetic fields in Josephson junctions fabricated with ferromagnetic barrier layers

Abd El Qader, M., Singh, R., Galvin, S. N., Yu, L., Rowell, J. M. & Newman, N., Jan 13 2014, In : Applied Physics Letters. 104, 2, 022602.

Research output: Contribution to journalArticle

Permalloys (trademark)
barrier layers
Josephson junctions
digital electronics
magnetic fields
57 Citations (Scopus)

The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting

Bhattacharya, C., Yu, Z., Rishel, M. J. & Hecht, S., May 27 2014, In : Biochemistry. 53, 20, p. 3264-3266 3 p.

Research output: Contribution to journalArticle

Bleomycin
Tumors
Cells
Neoplasms
Coloring Agents
85 Citations (Scopus)

The disaccharide moiety of bleomycin facilitates uptake by cancer cells

Schroeder, B. R., Ghare, M. I., Bhattacharya, C., Paul, R., Yu, Z., Zaleski, P. A., Bozeman, T. C., Rishel, M. J. & Hecht, S., Oct 1 2014, In : Journal of the American Chemical Society. 136, 39, p. 13641-13656 16 p.

Research output: Contribution to journalArticle

Disaccharides
Bleomycin
Cells
Tumors
DNA
116 Citations (Scopus)

The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure

Kendrick, S., Kang, H. J., Alam, M. P., Madathil, M. M., Agrawal, P., Gokhale, V., Yang, D., Hecht, S. & Hurley, L. H., Mar 19 2014, In : Journal of the American Chemical Society. 136, 11, p. 4161-4171 11 p.

Research output: Contribution to journalArticle

Gene expression
DNA
Modulation
Gene Expression
Stabilization
12 Citations (Scopus)

The National Biomarker Development Alliance accelerating the translation of biomarkers to the clinic

Barker, A., Compton, C. & Poste, G., Jul 1 2014, In : Biomarkers in Medicine. 8, 6, p. 873-876 4 p.

Research output: Contribution to journalArticle

Precision Medicine
Translational Medical Research
Biomarkers
104 Citations (Scopus)

The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules

Kang, H. J., Kendrick, S., Hecht, S. & Hurley, L. H., Mar 19 2014, In : Journal of the American Chemical Society. 136, 11, p. 4172-4185 14 p.

Research output: Contribution to journalArticle

Switch Genes
Heterogeneous-Nuclear Ribonucleoproteins
Gene expression
Switches
Gene Expression
51 Citations (Scopus)

The γ-aminobutyric acid shunt contributes to closing the tricarboxylic acid cycle in Synechocystis sp. PCC 6803

Xiong, W., Brune, D. & Vermaas, W., Aug 1 2014, In : Molecular Microbiology. 93, 4, p. 786-796 11 p.

Research output: Contribution to journalArticle

2-oxoglutarate decarboxylase
Aminobutyrates
Synechocystis
Citric Acid Cycle
Succinic Acid
15 Citations (Scopus)

Tryptophan-based fluorophores for studying protein conformational changes

Talukder, P., Chen, S., Liu, C. T., Baldwin, E. A., Benkovic, S. J. & Hecht, S., Nov 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 21, p. 5924-5934 11 p.

Research output: Contribution to journalArticle

Fluorophores
Tryptophan
Fluorescence
Proteins
Enzyme activity
2013
11 Citations (Scopus)

An optimized pyrimidinol multifunctional radical quencher

Khdour, O., Arce, P. M., Roy, B. & Hecht, S., Aug 8 2013, In : ACS Medicinal Chemistry Letters. 4, 8, p. 724-729 6 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
coenzyme Q10
Oxidative stress
Lymphocytes
Antioxidants
3 Citations (Scopus)

A structurally simplified analogue of geldanamycin exhibits neuroprotective activity

Madathil, M. M., Khdour, O., Jaruvangsanti, J. & Hecht, S., Oct 10 2013, In : ACS Medicinal Chemistry Letters. 4, 10, p. 953-957 5 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
Lymphocytes
Cytoprotection
Mitochondrial Membrane Potential
Cytotoxicity
15 Citations (Scopus)

Characterization of Bleomycin-Mediated Cleavage of a Hairpin DNA Library

Segerman, Z. J., Roy, B. & Hecht, S., Aug 6 2013, In : Biochemistry. 52, 31, p. 5315-5327 13 p.

Research output: Contribution to journalArticle

Bleomycin
Gene Library
DNA
DNA Cleavage
DNA Damage
4 Citations (Scopus)

ClpB1 overproduction in Synechocystis sp. strain PCC 6803 increases tolerance to rapid heat shock

Gonzalez-Esquer, C. R. & Vermaas, W., 2013, In : Applied and Environmental Microbiology. 79, 20, p. 6220-6227 8 p.

Research output: Contribution to journalArticle

Synechocystis
heat shock
Heat-Shock Proteins
heat shock proteins
cell viability
10 Citations (Scopus)

Criteria for improving the properties of ZnGeAs2 solar cells

Peshek, T. J., Zhang, L., Singh, R., Tang, Z., Vahidi, M., To, B., Coutts, T. J., Gessert, T. A., Newman, N. & Van Schilfgaarde, M., Aug 2013, In : Progress in Photovoltaics: Research and Applications. 21, 5, p. 906-917 12 p.

Research output: Contribution to journalArticle

Solar cells
solar cells
absorbers (materials)
Hole mobility
Borosilicate glass
40 Citations (Scopus)

Detection of dihydrofolate reductase conformational change by fret using two fluorescent amino acids

Chen, S., Fahmi, N. E., Wang, L., Bhattacharya, C., Benkovic, S. J. & Hecht, S., Sep 4 2013, In : Journal of the American Chemical Society. 135, 35, p. 12924-12927 4 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Amino acids
Amino Acids
Fluorophores
Energy Transfer

Effect of helium ion irradiation on the tunneling behavior in niobium/aluminum-aluminum oxide/niobium josephson junctions

Zhang, T., Kopas, C., Yu, L., Carpenter, R., Qader, M. A., Huang, M., Singh, R., Mardinly, J., Cantor, R., Rowell, J. M. & Newman, N., 2013, In : IEEE Transactions on Applied Superconductivity. 23, 4, 1101610.

Research output: Contribution to journalArticle

Niobium
Niobium oxide
Helium
Aluminum Oxide
helium ions
15 Citations (Scopus)

Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection

Fash, D. M., Khdour, O., Sahdeo, S. J., Goldschmidt, R., Jaruvangsanti, J., Dey, S., Arce, P. M., Collin, V. C., Cortopassi, G. A. & Hecht, S., Apr 15 2013, In : Bioorganic and Medicinal Chemistry. 21, 8, p. 2346-2354 9 p.

Research output: Contribution to journalArticle

coenzyme Q10
diethyl maleate
Cytoprotection
Electron Transport
Ubiquinone
15 Citations (Scopus)

Effects of cytoprotective antioxidants on lymphocytes from representative mitochondrial neurodegenerative diseases

Goldschmidt, R., Arce, P. M., Khdour, O., Collin, V. C., Dey, S., Jaruvangsanti, J., Fash, D. M. & Hecht, S., Feb 15 2013, In : Bioorganic and Medicinal Chemistry. 21, 4, p. 969-978 10 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Mitochondrial Diseases
coenzyme Q10
Lymphocytes
Neurodegenerative Diseases

Erratum: Characterization of bleomycin-mediated cleavage of a hairpin DNA library (Biochemistry (2013) 52:31 (5313-5327) DOI:10.1021/bi400779r)

Segerman, Z. J., Roy, B. & Hecht, S., Sep 10 2013, In : Biochemistry. 52, 36, p. 6300 1 p.

Research output: Contribution to journalArticle

Biochemistry
Bleomycin
Gene Library
2 Citations (Scopus)

Erratum: The dominance of paramagnetic loss in microwave dielectric ceramics at cryogenic temperatures (Applied Physics Letters (2012) 101 (252901))

Liu, L., Matusevich, A., Garg, C. & Newman, N., Jan 28 2013, In : Applied Physics Letters. 102, 4, 049901.

Research output: Contribution to journalArticle

cryogenic temperature
ceramics
microwaves
physics
10 Citations (Scopus)

Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification

Chen, S., Fahmi, N. E., Bhattacharya, C., Wang, L., Jin, Y., Benkovic, S. J. & Hecht, S., Nov 26 2013, In : Biochemistry. 52, 47, p. 8580-8589 10 p.

Research output: Contribution to journalArticle

Phenylalanine
Derivatives
Proteins
Amino Acids
Tetrahydrofolate Dehydrogenase
6 Citations (Scopus)

Growth of epitaxial pyrite (FeS2) thin films using sequential evaporation

Vahidi, M., Lehner, S. W., Buseck, P. R. & Newman, N., Nov 2013, In : Acta Materialia. 61, 19, p. 7392-7398 7 p.

Research output: Contribution to journalArticle

Pyrites
Evaporation
Thin films
Energy gap
Semiconductor materials
14 Citations (Scopus)

Improving the affinity of SL0101 for RSK using structure-based design

Mrozowski, R. M., Vemula, R., Wu, B., Zhang, Q., Schroeder, B. R., Hilinski, M. K., Clark, D. E., Hecht, S., O'Doherty, G. A. & Lannigan, D. A., Feb 14 2013, In : ACS Medicinal Chemistry Letters. 4, 2, p. 175-179 5 p.

Research output: Contribution to journalArticle

Phosphotransferases
Rhamnose
Biological Products
Protein Kinases
Half-Life
40 Citations (Scopus)

Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center

Maini, R., Nguyen, D. T., Chen, S., Dedkova, L., Chowdhury, S. R., Alcala-Torano, R. & Hecht, S., Mar 1 2013, In : Bioorganic and Medicinal Chemistry. 21, 5, p. 1088-1096 9 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
Tetrahydrofolate Dehydrogenase
Ribosomes
Amino Acids
Alanine
3 Citations (Scopus)

Investigations of the disorder in the TaxN thin films: On the first order Raman spectrum of the rock salt crystal structure

Očko, M., Žonja, S., Salamon, K., Ivanda, M., Yu, L. & Newman, N., Jul 28 2013, In : Journal of Applied Physics. 114, 4, 043707.

Research output: Contribution to journalArticle

halites
disorders
Raman spectra
crystal structure
defects
2 Citations (Scopus)

Perspective from the founding editors

Juliano, R., Poste, G. & Tomlinson, E., Jan 2013, In : Advanced Drug Delivery Reviews. 65, 1, p. 3-4 2 p.

Research output: Contribution to journalArticle

Pharmaceutical Technology
Pharmaceutical Chemistry
Drug Delivery Systems
Cost-Benefit Analysis
Chronic Disease
14 Citations (Scopus)

Polyhydroxybutyrate particles in Synechocystis sp. PCC 6803: Facts and fiction

Tsang, T. K., Roberson, R. & Vermaas, W., Nov 2013, In : Photosynthesis Research. 118, 1-2, p. 37-49 13 p.

Research output: Contribution to journalArticle

polyhydroxybutyrate
Synechocystis sp. PCC 6803
Synechocystis
Cyanobacteria
granules