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2019

DNA-affibody nanoparticle delivery system for cisplatin-based breast cancer chemotherapy

Zhang, C., Zhang, H. L., Han, M. N., Yang, X. L., Pei, C. H., Xu, Z. D., Du, J., Li, W. & Chen, S., Jan 1 2019, In : RSC Advances. 9, 4, p. 1982-1989 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Expanding the Scope of Protein Synthesis Using Modified Ribosomes

Dedkova, L. & Hecht, S., Apr 24 2019, In : Journal of the American Chemical Society. 141, 16, p. 6430-6447 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid

Chen, S., Ji, X., Gao, M., Dedkova, L. & Hecht, S., Apr 10 2019, In : Journal of the American Chemical Society. 141, 14, p. 5597-5601 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Influence of substrate temperature on properties of pyrite thin films deposited using a sequential coevaporation technique

Walimbe, A., Wertheim, A., Ravi, A., Kopas, C., Saxena, A., Singh, R., Lehner, S. W., Domenico, J., Makar, J., Carpenter, R., Buseck, P. R. & Newman, N., Jan 1 2019, In : Thin Solid Films. 669, p. 49-55 7 p.

Research output: Contribution to journalArticle

Selective detection of dengue virus serotypes using tandem toehold-mediated displacement reactions

Gao, M., Waggoner, J. J., Hecht, S. M. & Chen, S., Jan 1 2019, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

2018

Better Resolution of High-Spin Cobalt Hyperfine at Low Frequency: Co-Doped Ba(Zn1/3Ta2/3)O₃ as a Model Complex

Antholine, W. E., Zhang, S., Gonzales, J. & Newman, N., Nov 9 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

2 Scopus citations

Catalytic conversion of cyanobacteria-derived fatty acids to alkanes for biorenewable synthetic paraffinic kerosene

Schulz, T. C., Oelschlager, M., Thompson, S. T., Vermaas, W., Nielsen, D. & Lamb, H. H., Jan 1 2018, In : Sustainable Energy and Fuels. 2, 4, p. 882-893 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels

Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P., Hecht, S. & Khdour, O., Oct 1 2018, In : Data in Brief. 20, p. 1105-1114 10 p.

Research output: Contribution to journalArticle

Clean to dirty limit and T c suppression in NdFeAsO0.7F0.3 studied by H c2 analysis

Pallecchi, I., Tarantini, C., Shen, Y., Singh, R., Newman, N., Cheng, P., Jia, Y., Wen, H. H. & Putti, M., Feb 14 2018, In : Superconductor Science and Technology. 31, 3, 034007.

Research output: Contribution to journalArticle

Effect of α-particle irradiation on a NdFeAs(O,F) thin film

Tarantini, C., Iida, K., Sumiya, N., Chihara, M., Hatano, T., Ikuta, H., Singh, R., Newman, N. & Larbalestier, D. C., Feb 5 2018, In : Superconductor Science and Technology. 31, 3, 034002.

Research output: Contribution to journalArticle

4 Scopus citations

Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia

Khdour, O., Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P. & Hecht, S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

4 Scopus citations

Magnetic properties of chromium-doped Ni80Fe20 thin films

Devonport, A., Vishina, A., Singh, R., Edwards, M., Zheng, K., Domenico, J., Rizzo, N. D., Kopas, C., van Schilfgaarde, M. & Newman, N., Aug 15 2018, In : Journal of Magnetism and Magnetic Materials. 460, p. 193-202 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs

Mastroeni, D., Nolz, J., Khdour, O., Sekar, S., Delvaux, E., Cuyugan, L., Liang, W. S., Hecht, S. & Coleman, P., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

8 Scopus citations

Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells

Khdour, O., Bandyopadhyay, I., Visavadiya, N. P., Roy Chowdhury, S. & Hecht, S., Jan 1 2018, In : MedChemComm. 9, 9, p. 1491-1501 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes

Domenyuk, V., Gatalica, Z., Santhanam, R., Wei, X., Stark, A., Kennedy, P., Toussaint, B., Levenberg, S., Wang, J., Xiao, N., Greil, R., Rinnerthaler, G., Gampenrieder, S. P., Heimberger, A. B., Berry, D. A., Barker, A., Quackenbush, J., Marshall, J. L., Poste, G., Vacirca, J. L. & 9 others, Vidal, G. A., Schwartzberg, L. S., Halbert, D. D., Voss, A., Magee, D., Miglarese, M. R., Famulok, M., Mayer, G. & Spetzler, D., Dec 1 2018, In : Nature Communications. 9, 1, 1219.

Research output: Contribution to journalArticle

8 Scopus citations

Rapid detection of a dengue virus RNA sequence with single molecule sensitivity using tandem toehold-mediated displacement reactions

Gao, M., Daniel, D., Zou, H., Jiang, S., Lin, S., Huang, C., Hecht, S. & Chen, S., Jan 1 2018, In : Chemical Communications. 54, 8, p. 968-971 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Study of the Lyase Activity of Human DNA Polymerase β Using Analogues of the Intermediate Schiff Base Complex

Daskalova, S. M., Bai, X. & Hecht, S., May 8 2018, In : Biochemistry. 57, 18, p. 2711-2722 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Switching microwave dielectric resonators from a high-Q on state to an off state using low-field electron paramagnetic resonance transitions

Gonzales, J., Zhang, C., Gajare, S. G. & Newman, N., Jul 30 2018, In : Applied Physics Letters. 113, 5, 052903.

Research output: Contribution to journalArticle

2017

Converging and emerging threats to health security

Raina Macintyre, C., Engells, T. E., Scotch, M., Heslop, D. J., Gumel, A., Poste, G., Chen, X., Herche, W., Steinhöfel, K., Lim, S. & Broom, A., Nov 27 2017, (Accepted/In press) In : Environment Systems and Decisions. p. 1-10 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

DNA-affibody nanoparticles for inhibiting breast cancer cells overexpressing HER2

Zhang, Y., Jiang, S., Zhang, D., Bai, X., Hecht, S. & Chen, S., 2017, In : Chemical Communications. 53, 3, p. 573-576 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of non-stoichiometry on the densification, phase purity, microstructure, crystal structure, and dielectric loss of Ba(Co1/3Nb2/3)O3 ceramics

Sayyadi-Shahraki, A., Taheri-Nassaj, E., Gonzales, J., Newman, N. & Kolodiazhnyi, T., Aug 1 2017, In : Journal of the European Ceramic Society. 37, 10, p. 3335-3346 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Enhanced Binding Affinity for an i-Motif DNA Substrate Exhibited by a Protein Containing Nucleobase Amino Acids

Bai, X., Talukder, P., Daskalova, S. M., Roy, B., Chen, S., Li, Z., Dedkova, L. & Hecht, S., Apr 5 2017, In : Journal of the American Chemical Society. 139, 13, p. 4611-4614 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Fundamental mechanisms responsible for the temperature coefficient of resonant frequency in microwave dielectric ceramics

Zhang, S., Sahin, H., Torun, E., Peeters, F., Martien, D., DaPron, T., Dilley, N. & Newman, N., Apr 1 2017, In : Journal of the American Ceramic Society. 100, 4, p. 1508-1516 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Improvement in the magnetic properties of NiFe thin films on thick Nb electrodes using oxidation and low energy Ar ion milling

Singh, R., Rizzo, N., Bertram, M., Zheng, K. & Newman, N., Nov 18 2017, (Accepted/In press) In : IEEE Magnetics Letters.

Research output: Contribution to journalArticle

2 Scopus citations

Incorporation of Phosphorylated Tyrosine into Proteins: In Vitro Translation and Study of Phosphorylated IκB-α and Its Interaction with NF-κB

Chen, S., Maini, R., Bai, X., Nangreave, R. C., Dedkova, L. & Hecht, S., Oct 11 2017, In : Journal of the American Chemical Society. 139, 40, p. 14098-14108 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants

Chevalier, A., Khdour, O., Schmierer, M., Bandyopadhyay, I. & Hecht, S., Mar 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 5, p. 1703-1716 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibition of Human Cancer Cell Growth by Analogues of Antimycin A

Zhang, Y., Chevalier, A., Khdour, O., Soto, L. M. & Hecht, S., May 20 2017, (Accepted/In press) In : Planta Medica.

Research output: Contribution to journalArticle

1 Scopus citations

Large Uniaxial Anisotropy Induced in Soft Ferromagnetic Thin Films by Oblique Deposition of Underlayer

Singh, R., Rizzo, N. D., Boochakravarthy, A. & Newman, N., Nov 29 2017, (Accepted/In press) In : IEEE Magnetics Letters.

Research output: Contribution to journalArticle

3 Scopus citations

Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction

Roy Chowdhury, S., Khdour, O., Bandyopadhyay, I. & Hecht, S., Oct 15 2017, In : Bioorganic and Medicinal Chemistry. 25, 20, p. 5537-5547 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Origin of dielectric loss in Ba(Co1/3Nb2/3)O3 microwave ceramics

Sayyadi-Shahraki, A., Taheri-Nassaj, E., Sharifi, H., Gonzales, J., Kolodiazhnyi, T. & Newman, N., Jan 1 2017, (Accepted/In press) In : Journal of the American Ceramic Society.

Research output: Contribution to journalArticle

9 Scopus citations

Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach

Domenyuk, V., Zhong, Z., Stark, A., Xiao, N., O'Neill, H. A., Wei, X., Wang, J., Tinder, T. T., Tonapi, S., Duncan, J., Hornung, T., Hunter, A., Miglarese, M. R., Schorr, J., Halbert, D. D., Quackenbush, J., Poste, G., Berry, D. A., Mayer, G., Famulok, M. & 1 others, Spetzler, D., Feb 20 2017, In : Scientific Reports. 7, 42741.

Research output: Contribution to journalArticle

18 Scopus citations

Prescreening of Nicotine Hapten Linkers in Vitro To Select Hapten-Conjugate Vaccine Candidates for Pharmacokinetic Evaluation in Vivo

Arutla, V., Leal, J., Liu, X., Sokalingam, S., Raleigh, M., Adaralegbe, A., Liu, L., Pentel, P. R., Hecht, S. & Chang, Y., May 8 2017, In : ACS Combinatorial Science. 19, 5, p. 286-298 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues

Daskalova, S. M., Bhattacharya, C., Dedkova, L. & Hecht, S., Jan 24 2017, In : Biochemistry. 56, 3, p. 500-513 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

The magnetic, electrical and structural properties of copper-permalloy alloys

Qader, M. A., Vishina, A., Yu, L., Garcia, C., Singh, R., Rizzo, N. D., Huang, M., Chamberlin, R., Belashchenko, K. D., van Schilfgaarde, M. & Newman, N., Nov 15 2017, In : Journal of Magnetism and Magnetic Materials. 442, p. 45-52 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

In-situ electron paramagnetic resonance studies of paramagnetic point defects in superconducting microwave resonators

Zhang, S., Kopas, C., Wagner, B., Queen, D. & Newman, N., Sep 19 2016, In : Applied Physics Letters. 109, 12, 122602.

Research output: Contribution to journalArticle

Interaction of Individual Structural Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA

Roy, B., Talukder, P., Kang, H. J., Tsuen, S. S., Alam, M. P., Hurley, L. H. & Hecht, S., Aug 31 2016, In : Journal of the American Chemical Society. 138, 34, p. 10950-10962 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting

Chevalier, A., Zhang, Y., Khdour, O., Kaye, J. B. & Hecht, S., Sep 21 2016, In : Journal of the American Chemical Society. 138, 37, p. 12009-12012 4 p.

Research output: Contribution to journalArticle

67 Scopus citations

Nuclear but not mitochondrial-encoded OXPHOS genes are altered in aging, mild cognitive impairment, and Alzheimer's disease

Mastroeni, D., Khdour, O., Delvaux, E., Nolz, J., Olsen, G., Berchtold, N., Cotman, C., Hecht, S. & Coleman, P., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

21 Scopus citations

Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability

Chevalier, A., Alam, M. P., Khdour, O., Schmierer, M., Arce, P. M., Cripe, C. D. & Hecht, S., Nov 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 21, p. 5206-5220 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prioritization schema for immunotherapy clinical trials in glioblastoma

Hodges, T. R., Ferguson, S. D., Caruso, H. G., Kohanbash, G., Zhou, S., Cloughesy, T. F., Berger, M. S., Poste, G., Khasraw, M., Ba, S., Jiang, T., Mikkelson, T., Yung, W. K. A., de Groot, J. F., Fine, H., Cantley, L. C., Mellinghoff, I. K., Mitchell, D. A., Okada, H. & Heimberger, A. B., May 16 2016, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

8 Scopus citations

Selective Functionalization of Antimycin A Through an N-Transacylation Reaction

Chevalier, A., Zhang, Y., Khdour, O. & Hecht, S., May 20 2016, In : Organic Letters. 18, 10, p. 2395-2398 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Synthesis and evaluation of a library of fluorescent dipeptidomimetic analogues as substrates for modified bacterial ribosomes

Chowdhury, S. R., Chauhan, P. S., Dedkova, L., Bai, X., Chen, S., Talukder, P. & Hecht, S., May 3 2016, In : Biochemistry. 55, 17, p. 2427-2440 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synthesis of alanyl nucleobase amino acids and their incorporation into proteins

Talukder, P., Dedkova, L., Ellington, A. D., Yakovchuk, P., Lim, J., Anslyn, E. V. & Hecht, S., Sep 15 2016, In : Bioorganic and Medicinal Chemistry. 24, 18, p. 4177-4187 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations
2015

A dedicated type II NADPH dehydrogenase performs the penultimate step in the biosynthesis of vitamin K<inf>1</inf> in synechocystis and arabidopsis

Fatihi, A., Latimer, S., Schmollinger, S., Block, A., Dussault, P. H., Vermaas, W., Merchant, S. S. & Basset, G. J., Jun 1 2015, In : Plant Cell. 27, 6, p. 1730-1741 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Beyond Ebola: Lessons to mitigate future pandemics

Castillo-Chavez, C., Curtiss, R., Daszak, P., Levin, S. A., Patterson-Lomba, O., Perrings, C., Poste, G. & Towers, S., Jul 1 2015, In : The Lancet Global Health. 3, 7, p. e354-e355

Research output: Contribution to journalArticle

16 Scopus citations

Breaking down silos for improved biomarker development: An interview with George Poste

Poste, G., Nov 1 2015, In : Expert Review of Molecular Diagnostics. 15, 8, p. 975-978 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction

Talukder, P., Chen, S., Roy, B., Yakovchuk, P., Spiering, M. M., Alam, M. P., Madathil, M. M., Bhattacharya, C., Benkovic, S. J. & Hecht, S., Dec 29 2015, In : Biochemistry. 54, 51, p. 7457-7469 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase

Bernatchez, J. A., Paul, R., Tchesnokov, E. P., Ngure, M., Beilhartz, G. L., Berghuis, A. M., Lavoie, R., Li, L., Auger, A., Melnyk, R. A., Grobler, J. A., Miller, M. D., Hazuda, D. J., Hecht, S. & Götte, M., Jan 16 2015, In : Journal of Biological Chemistry. 290, 3, p. 1474-1484 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Expedited quantification of mutant ribosomal RNA by binary deoxyribozyme (BiDz) sensors

Gerasimova, Y. V., Yakovchuk, P., Dedkova, L., Hecht, S. & Kolpashchikov, D. M., Oct 1 2015, In : RNA. 21, 10, p. 1834-1843 10 p.

Research output: Contribution to journalArticle

10 Scopus citations