Applied Structural Discovery, Center for (ASD)

Research output

Research output per year 1978 2015 2016 2017 2018 2023

• 219 Article
• 59 Paper
• 52 Other contribution
• 34 Conference contribution
• 41 More
  • 11 Review article
  • 9 Chapter
  • 9 Comment/debate
  • 5 Editorial
  • 3 Patent
  • 2 Book
  • 2 Short survey

Research output per year

Research output per year

Search results

• 2023

  Directing Molecular Weaving of Covalent Organic Frameworks and Their Dimensionality by Angular Control

  Han, X., Neumann, S. E., Nannenga, B. L., Wang, K., Li, K. K. Y., Mirzaei, S., Yao, X., Zhu, C., Gao, M. Y., Zhang, Y. B., Cui, Y. & Yaghi, O. M., Oct 25 2023, In: Journal of the American Chemical Society. 145, 42, p. 22885-22889 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Metal-Organic Frameworks 100%
  • Coordination Complexes 82%
  • Fences 73%
  • Aldehydes 66%
  • X-Ray Diffraction 66%
  3 Scopus citations

• Molecular weaving of chicken-wire covalent organic frameworks

  Han, X., Ma, T., Nannenga, B. L., Yao, X., Neumann, S. E., Kumar, P., Kwon, J., Rong, Z., Wang, K., Zhang, Y., Navarro, J. A. R., Ritchie, R. O., Cui, Y. & Yaghi, O. M., Sep 14 2023, In: Chem. 9, 9, p. 2509-2517 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metal-Organic Frameworks 100%
  • Coordination Complexes 82%
  • Extended Structure 66%
  • Chickens 54%
  • Metal complexes 45%
  5 Scopus citations

• Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser

  Jernigan, R. J., Logeswaran, D., Doppler, D., Nagaratnam, N., Sonker, M., Yang, J. H., Ketawala, G., Martin-Garcia, J. M., Shelby, M. L., Grant, T. D., Mariani, V., Tolstikova, A., Sheikh, M. Z., Yung, M. C., Coleman, M. A., Zaare, S., Kaschner, E. K., Rabbani, M. T., Nazari, R., Zacks, M. A., & 16 othersHayes, B., Sierra, R. G., Hunter, M. S., Lisova, S., Batyuk, A., Kupitz, C., Boutet, S., Hansen, D. T., Kirian, R. A., Schmidt, M., Fromme, R., Frank, M., Ros, A., Chen, J. J. L., Botha, S. & Fromme, P., Feb 2 2023, In: Structure. 31, 2, p. 138-151.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Lasers 54%
  • Electrons 54%
  • X-Rays 52%
  • Crystallography 48%
  5 Scopus citations

• Soluble and stable cyanophycin synthetase expression enhances heterologous cyanophycin production in Escherichia coli

  Swain, K., Sharon, I., Blackson, W., Parrish, S., Tekel, S., Schmeing, T. M., Nielsen, D. R. & Nannenga, B. L., Jun 2023, In: Biochemical Engineering Journal. 195, 108916.

  Research output: Contribution to journal › Article › peer-review

  • cyanophycin 100%
  • Escherichia coli 62%
  • Ligases 53%
  • Biopolymer 47%
  • Enzymes 45%
  4 Scopus citations

• Structure determination of a DNA crystal by MicroED

  Haymaker, A., Bardin, A. A., Gonen, T., Martynowycz, M. W. & Nannenga, B. L., Dec 7 2023, In: Structure. 31, 12, p. 1499-1503.e2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • tri(cytidylic acid-guanidylic acid) 100%
  • tri(deoxycytidylic acid-deoxyguanylic acid) 97%
  • Electrons 66%
  • DNA 46%
  • Nucleic Acids 20%
  1 Scopus citations

• The 2023 Structural Biology Summit at UCLA

  Nannenga, B. L. & Gonen, T., Dec 7 2023, In: Structure. 31, 12, p. 1485-1486 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Los Angeles 100%

• The next decade in structural biology

  Walsh, M. A., Nannenga, B. L., Gonen, T., Sexton, P. M., Wootten, D., Chiu, W., Sun, F., Carragher, B., Potter, C. S., Agard, D. & Burley, S. K., Nov 2 2023, In: Structure. 31, 11, p. 1284-1288 5 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Anniversaries and Special Events 100%
• 2022

  A Crystalline 1D Dynamic Covalent Polymer

  De Bolòs, E., Martínez-Abadía, M., Hernández-Culebras, F., Haymaker, A., Swain, K., Strutyński, K., Weare, B. L., Castells-Gil, J., Padial, N. M., Martí-Gastaldo, C., Khlobystov, A. N., Saeki, A., Melle-Franco, M., Nannenga, B. L. & Mateo-Alonso, A., Aug 31 2022, In: Journal of the American Chemical Society. 144, 34, p. 15443-15450 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Crystalline materials 100%
  • Polymers 85%
  • Charge Transfer 66%
  • Electron Diffraction 48%
  • Charge transfer 34%
  13 Scopus citations

• Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

  Boyd, R. J., Olson, T. L., Zook, J. D., Stein, D., Aceves, M., Lin, W. H., Craciunescu, F. M., Hansen, D. T., Anastasiadis, P. Z., Singharoy, A. & Fromme, P., Jul 2022, In: FASEB Journal. 36, 7, e22378.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rho Guanine Nucleotide Exchange Factors 100%
  • Guanine Nucleotide Exchange Factors 73%
  • Glioblastoma 64%
  • Guanine 63%
  • Nucleotide 53%
  1 Scopus citations

• Electron-counting MicroED data with the K2 and K3 direct electron detectors

  Clabbers, M. T. B., Martynowycz, M. W., Hattne, J., Nannenga, B. L. & Gonen, T., Dec 2022, In: Journal of Structural Biology. 214, 4, 107886.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Electrons 100%
  • Cryoelectron Microscopy 24%
  • Motion Pictures 19%
  • Data Accuracy 18%
  4 Scopus citations

• Exploring Structure-Function Relationships Governing Activity of the Cyanobacterial Bicarbonate Transporter SbtA

  Parrish, S., Jones, C., Godar, A., Nielsen, D. & Nannenga, B. L., 2022, 2022 AIChE Annual Meeting. American Institute of Chemical Engineers, (AIChE Annual Meeting, Conference Proceedings; vol. 2022-November).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria

  Puskar, R., Du Truong, C., Swain, K., Chowdhury, S., Chan, K. Y., Li, S., Cheng, K. W., Wang, T. Y., Poh, Y. P., Mazor, Y., Liu, H., Chou, T. F., Nannenga, B. L. & Chiu, P. L., Dec 2022, In: Nature communications. 13, 1, 5824.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chlorobi 100%
  • Energy Transfer 69%
  • bacteria 56%
  • Asymmetry 56%
  • sulfur 50%
  4 Scopus citations

• Photomechanochemical control over stereoselectivity in the [2 + 2] photodimerization of acenaphthylene

  Biswas, S., Banerjee, S., Shlain, M. A., Bardin, A. A., Ulijn, R. V., Nannenga, B. L., Rappe, A. M. & Braunschweig, A. B., Jun 29 2022, In: Faraday Discussions. 241, p. 266-277 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • acenaphthylene 100%
  • Cyclobutanes 83%
  • cyclobutane 76%
  • Acenaphthylene 68%
  • Cyclobutane 57%
  6 Scopus citations

• Protein-Nanoparticle Complex Structure Determination by Cryo-Electron Microscopy

  Sen, S., Thaker, A., Sirajudeen, L., Williams, D. & Nannenga, B. L., Oct 17 2022, In: ACS Applied Bio Materials. 5, 10, p. 4696-4700 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cryoelectron Microscopy 100%
  • Cryo-Electron Microscopy 96%
  • Electron microscopy 94%
  • Nanoparticles 72%
  • Nanostructured materials 68%
  3 Scopus citations

• Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor

  Zhang, S., Hansen, D. T., Martin-Garcia, J. M., Zook, J. D., Pan, S., Craciunescu, F. M., Burnett, J. C. & Fromme, P., Dec 2022, In: Scientific reports. 12, 1, 11824.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • atrial natriuretic factor receptor A 100%
  • Crystallography 89%
  • Guanylate Cyclase 22%
  • Natriuretic Peptides 22%
  • Signal Transduction 13%
  1 Scopus citations

• Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis

  Nagaratnam, N., Martin-Garcia, J. M., Yang, J. H., Goode, M. R., Ketawala, G., Craciunescu, F. M., Zook, J. D., Sonowal, M., Williams, D., Grant, T. D., Fromme, R., Hansen, D. T. & Fromme, P., Aug 2022, In: PloS one. 17, 8 August, e0267370.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • OMPA outer membrane proteins 100%
  • Francisella tularensis 89%
  • Membrane Proteins 51%
  • Tularemia 32%
  • Membranes 23%
  1 Scopus citations
• 2021

  Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease

  Moran, M. W., Ramirez, E. P., Zook, J. D., Saarinen, A. M., Baravati, B., Goode, M. R., Laloudakis, V., Kaschner, E. K., Olson, T. L., Craciunescu, F. M., Hansen, D. T., Liu, J. & Fromme, P., Jul 2021, In: PloS one. 16, 7 July, e0249164.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Non-alcoholic Fatty Liver Disease 100%
  • Enzymes 50%
  • Liver 35%
  • Drug Design 26%
  • Lipase 25%
  3 Scopus citations

• Efficient free triplet generation follows singlet fission in diketopyrrolopyrrole polymorphs with goldilocks coupling

  Levine, A. M., He, G., Bu, G., Ramos, P., Wu, F., Soliman, A., Serrano, J., Pietraru, D., Chan, C., Batteas, J. D., Kowalczyk, M., Jang, S. J., Nannenga, B. L., Sfeir, M. Y., Tsai, E. H. R. & Braunschweig, A. B., Jun 10 2021, In: Journal of Physical Chemistry C. 125, 22, p. 12207-12213 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Singlet fission 100%
  • Polymorphism 53%
  • Fission 47%
  • fission 39%
  • Annealing 33%
  13 Scopus citations

• Imaging by intensity interferometry of x-ray fluorescence at a compact x-ray free-electron laser

  Shevchuk, A. S. H., Spence, J. C. H., Kirian, R. A., Graves, W. S. & Schmidt, K. E., Aug 2021, In: Physical Review A. 104, 2, 023514.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • x ray fluorescence 100%
  • x ray lasers 92%
  • free electron lasers 74%
  • interferometry 62%
  • atoms 36%
  2 Scopus citations

• MicroED for the study of protein–ligand interactions and the potential for drug discovery

  Clark, L. J., Bu, G., Nannenga, B. L. & Gonen, T., Dec 2021, In: Nature Reviews Chemistry. 5, 12, p. 853-858 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Microcrystals 100%
  • Drug Discovery 76%
  • Electron diffraction 74%
  • Electron Diffraction 57%
  • X ray crystallography 32%
  5 Scopus citations

• MicroED Sample Preparation and Data Collection For Protein Crystals

  Bu, G. & Nannenga, B. L., 2021, Methods in Molecular Biology. Humana Press Inc., p. 287-297 11 p. (Methods in Molecular Biology; vol. 2215).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Electrons 100%
  • Proteins 46%
  3 Scopus citations

• MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP

  Martynowycz, M. W., Shiriaeva, A., Ge, X., Hattne, J., Nannenga, B. L., Cherezov, V. & Gonen, T., Sep 7 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 36, e2106041118.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Purinergic P1 Receptors 100%
  • Nanoparticles 71%
  • Electrons 64%
  • Adenosine A2A Receptors 56%
  • G-Protein-Coupled Receptors 40%
  24 Scopus citations

• Preface

  Gonen, T. & Nannenga, B. L., 2021, In: Methods in Molecular Biology. 2215, p. v

  Research output: Contribution to journal › Editorial › peer-review

• Protein Engineering to Improve the Function of BicA: A Constitutively Expressed, High-Flux Bicarbonate Transporter in Synechococcus sp. PCC 7002

  Parrish, S., Bu, G., Jones, C., Nielsen, D. & Nannenga, B., 2021, 2021 AIChE Annual Meeting. American Institute of Chemical Engineers, (AIChE Annual Meeting, Conference Proceedings; vol. 2021-November).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Proteins 100%
  • Fluxes 88%
  • Carbon Cycle 83%
  • Purification 73%
  • Solar Energy 59%

• Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma

  Olson, T. L., Zhang, S., Labban, D., Kaschner, E., Aceves, M., Iyer, S., Meza-Aguilar, J. D., Zook, J. D., Chun, E., Craciunescu, F. M., Liu, W., Shi, C. X., Stewart, A. K., Hansen, D. T., Meurice, N. & Fromme, P., Sep 2021, In: Protein Expression and Purification. 185, 105890.

  Research output: Contribution to journal › Article › peer-review

  • G-protein-coupled receptor kinase 6 100%
  • Drug Design 59%
  • Drug Discovery 53%
  • Multiple Myeloma 51%
  • Sf9 Cells 20%
  2 Scopus citations

• Publisher Correction: The cryo-EM method microcrystal electron diffraction (MicroED) (Nature Methods, (2019), 16, 5, (369-379), 10.1038/s41592-019-0395-x)

  Nannenga, B. L. & Gonen, T., May 2021, In: Nature Methods. 18, 5, p. 574 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Electron Diffraction 100%
  • Electrons 78%
  • Error 73%

• Quantitative agreement between dynamical rocking curves in ultrafast electron diffraction for x-ray lasers

  Malin, L. E., Graves, W. S., Holl, M., Spence, J. C. H., Nanni, E. A., Li, R. K., Shen, X. & Weathersby, S., Apr 2021, In: Ultramicroscopy. 223, 113211.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Electron diffraction 100%
  • x ray lasers 96%
  • Electron Diffraction 77%
  • X rays 68%
  • electron diffraction 64%
  1 Scopus citations

• Rapid Structural Analysis of a Synthetic Non-canonical Amino Acid by Microcrystal Electron Diffraction

  Gleason, P. R., Nannenga, B. L. & Mills, J. H., Jan 8 2021, In: Frontiers in Molecular Biosciences. 7, 609999.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Electron Diffraction 100%
  • Electrons 78%
  • Amino Acids 69%
  • Mass Spectrometry 66%
  • NMR Spectroscopy 65%
  6 Scopus citations

• Recent Developments Toward Integrated Metabolomics Technologies (UHPLC-MS-SPE-NMR and MicroED) for Higher-Throughput Confident Metabolite Identifications

  Ghosh, R., Bu, G., Nannenga, B. L. & Sumner, L. W., Sep 2 2021, In: Frontiers in Molecular Biosciences. 8, 720955.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolomics 100%
  • Metabolite 63%
  • Technology 59%
  • Medicago truncatula 32%
  • Fabaceae 23%
  8 Scopus citations

• Structural insights into the function of the catalytically active human Taspase1

  Nagaratnam, N., Delker, S. L., Jernigan, R., Edwards, T. E., Snider, J., Thifault, D., Williams, D., Nannenga, B. L., Stofega, M., Sambucetti, L., Hsieh, J. J., Flint, A. J., Fromme, P. & Martin-Garcia, J. M., Aug 5 2021, In: Structure. 29, 8, p. 873-885.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • human taspase1 100%
  • N-terminal nucleophile hydrolase 53%
  • Enzyme Precursors 17%
  • Glioblastoma 13%
  • Neoplasms 12%
  4 Scopus citations

• Structure-guided identification of a peptide for bio-enabled gold nanoparticle synthesis

  Thaker, A., Sirajudeen, L., Simmons, C. R. & Nannenga, B. L., Dec 2021, In: Biotechnology and bioengineering. 118, 12, p. 4867-4873 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gold nanoparticles 100%
  • Maltose 86%
  • Peptides 83%
  • Carrier Proteins 76%
  • Maltose-Binding Proteins 69%
  1 Scopus citations
• 2020

  Author Correction: Membrane directed expression in Escherichia coli of BBA57 and other virulence factors from the Lyme disease agent Borrelia burgdorferi (Scientific Reports, (2019), 9, 1, (17606), 10.1038/s41598-019-53830-x)

  Robertson, K. E., Truong, C. D., Craciunescu, F. M., Yang, J. H., Chiu, P. L., Fromme, P. & Hansen, D. T., Dec 1 2020, In: Scientific reports. 10, 1, 4163.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Borrelia burgdorferi 100%
  • Lyme Disease 95%
  • Virulence Factors 81%
  • Escherichia coli 55%
  • Membranes 46%

• Beam-sensitive metal-organic framework structure determination by microcrystal electron diffraction

  Banihashemi, F., Bu, G., Thaker, A., Williams, D., Lin, J. Y. S. & Nannenga, B. L., Sep 2020, In: Ultramicroscopy. 216, 113048.

  Research output: Contribution to journal › Article › peer-review

  • Metal-Organic Frameworks 100%
  • Microcrystals 98%
  • Electron diffraction 73%
  • microcrystals 68%
  • Electron Diffraction 56%
  15 Scopus citations

• Crystal structure and orientation of organic semiconductor thin films by microcrystal electron diffraction and grazing-incidence wide-angle X-ray scattering

  Levine, A. M., Bu, G., Biswas, S., Tsai, E. H. R., Braunschweig, A. B. & Nannenga, B. L., Apr 18 2020, In: Chemical Communications. 56, 30, p. 4204-4207 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Microcrystals 100%
  • Organic semiconductor materials 91%
  • X ray scattering 88%
  • Crystal orientation 78%
  • Electron diffraction 74%
  23 Scopus citations

• Heterologous expression and purification of the bicarbonate transporter BicA from Synechocystis sp. PCC 6803

  Bu, G., Parrish, S., Gleason, P. R., Nielsen, D. R. & Nannenga, B. L., Nov 2020, In: Protein Expression and Purification. 175, 105716.

  Research output: Contribution to journal › Article › peer-review

  • dodecyl maltopyranoside 100%
  • sulfate permease 96%
  • Sulfate Transporters 80%
  • Synechocystis 70%
  • Bicarbonates 50%
  1 Scopus citations

• MicroED methodology and development

  Nannenga, B. L., Jan 1 2020, In: Structural Dynamics. 7, 1, 014304.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microcrystals 100%
  • Electron diffraction 74%
  • Peptides 74%
  • Microcrystallinity 61%
  • Electron Diffraction 57%
  29 Scopus citations

• Segmented flow generator for serial crystallography at the European X-ray free electron laser

  Echelmeier, A., Cruz Villarreal, J., Messerschmidt, M., Kim, D., Coe, J. D., Thifault, D., Botha, S., Egatz-Gomez, A., Gandhi, S., Brehm, G., Conrad, C. E., Hansen, D. T., Madsen, C., Bajt, S., Meza-Aguilar, J. D., Oberthür, D., Wiedorn, M. O., Fleckenstein, H., Mendez, D., Knoška, J., & 51 othersMartin-Garcia, J. M., Hu, H., Lisova, S., Allahgholi, A., Gevorkov, Y., Ayyer, K., Aplin, S., Ginn, H. M., Graafsma, H., Morgan, A. J., Greiffenberg, D., Klujev, A., Laurus, T., Poehlsen, J., Trunk, U., Mezza, D., Schmidt, B., Kuhn, M., Fromme, R., Sztuk-Dambietz, J., Raab, N., Hauf, S., Silenzi, A., Michelat, T., Xu, C., Danilevski, C., Parenti, A., Mekinda, L., Weinhausen, B., Mills, G., Vagovic, P., Kim, Y., Kirkwood, H., Bean, R., Bielecki, J., Stern, S., Giewekemeyer, K., Round, A. R., Schulz, J., Dörner, K., Grant, T. D., Mariani, V., Barty, A., Mancuso, A. P., Weierstall, U., Spence, J. C. H., Chapman, H. N., Zatsepin, N., Fromme, P., Kirian, R. A. & Ros, A., Dec 1 2020, In: Nature communications. 11, 1, 4511.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Crystallography 100%
  • Free Electron 88%
  • crystallography 78%
  • free electron lasers 70%
  • generators 57%
  27 Scopus citations

• Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED

  Zhu, L., Bu, G., Jing, L., Shi, D., Lee, M. Y., Gonen, T., Liu, W. & Nannenga, B. L., Oct 6 2020, In: Structure. 28, 10, p. 1149-1159.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Electrons 100%
  • hexylene glycol 63%
  • Adenosine A2A Receptors 43%
  • Industrial Development 43%
  • Cryoelectron Microscopy 42%
  18 Scopus citations

• Tetragonal crystal form of the cyanobacterial bicarbonate-transporter regulator SbtB from Synechocystis sp. PCC 6803

  Bu, G., Simmons, C. R., Nielsen, D. R. & Nannenga, B. L., Sep 1 2020, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 76, p. 438-443 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Synechocystis 100%
  • transporter 93%
  • Cyanobacteria 85%
  • regulators 83%
  • carbonates 73%

• Wave optics simulation of grating-based X-ray phase-contrast imaging using 4D Mouse Whole Body (MOBY) phantom

  Sung, Y., Nelson, B., Shanblatt, E. R., Gupta, R., McCollough, C. H. & Graves, W. S., Nov 2020, In: Medical physics. 47, 11, p. 5761-5771 11 p.

  Research output: Contribution to journal › Article › peer-review

  • X-Rays 100%
  • Photons 45%
  • Noise 39%
  • Electrons 34%
  3 Scopus citations

• XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia

  Zook, J., Shekhar, M., Hansen, D., Conrad, C., Grant, T., Gupta, C., White, T., Barty, A., Basu, S., Zhao, Y., Zatsepin, N., Ishchenko, A., Batyuk, A., Gati, C., Li, C., Galli, L., Coe, J., Hunter, M., Liang, M., Weierstall, U., & 9 othersNelson, G., James, D., Stauch, B., Craciunescu, F., Thifault, D., Liu, W., Cherezov, V., Singharoy, A. & Fromme, P., May 5 2020, In: Structure. 28, 5, p. 540-547.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Francisella 100%
  • Tularemia 90%
  • Molecular Dynamics Simulation 69%
  • Lipoproteins 59%
  • Lasers 50%
  5 Scopus citations
• 2019

  Crystal structure of misoprostol bound to the labor inducer prostaglandin E ₂ receptor

  Audet, M., White, K. L., Breton, B., Zarzycka, B., Han, G. W., Lu, Y., Gati, C., Batyuk, A., Popov, P., Velasquez, J., Manahan, D., Hu, H., Weierstall, U., Liu, W., Shui, W., Katritch, V., Cherezov, V., Hanson, M. A. & Stevens, R. C., Jan 1 2019, In: Nature Chemical Biology. 15, 1, p. 11-17 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptors, Prostaglandin E, EP2 Subtype 100%
  • Misoprostol 75%
  • misoprostol acid 23%
  • Receptors, Prostaglandin E, EP3 Subtype 20%
  • Induced Labor 14%
  33 Scopus citations

• Electrophoretic exclusion microscale sample preparation for cryo-EM structural determination of proteins

  Zhu, F., Nannenga, B. L. & Hayes, M. A., Sep 1 2019, In: Biomicrofluidics. 13, 5, 054112.

  Research output: Contribution to journal › Article › peer-review

  • exclusion 100%
  • microbalances 91%
  • Proteins 82%
  • Sample Preparation 75%
  • proteins 72%
  4 Scopus citations

• Erratum to: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor (Nature Chemical Biology, (2019), 15, 1, (11-17), 10.1038/s41589-018-0160-y)

  Audet, M., White, K. L., Breton, B., Zarzycka, B., Han, G. W., Lu, Y., Gati, C., Batyuk, A., Popov, P., Velasquez, J., Manahan, D., Hu, H., Weierstall, U., Liu, W., Shui, W., Katritch, V., Cherezov, V., Hanson, M. A. & Stevens, R. C., Feb 1 2019, In: Nature Chemical Biology. 15, 2, p. 206 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Prostaglandin Receptors 100%
  • Moscow 93%
  • Misoprostol 90%
  • Russia 81%
  • Dinoprostone 67%

• Evaluation of the performance of classification algorithms for XFEL single-particle imaging data

  Shi, Y., Yin, K., Tai, X., DeMirci, H., Hosseinizadeh, A., Hogue, B., Li, H., Ourmazd, A., Schwander, P., Vartanyants, I. A., Yoon, C. H., Aquila, A. & Liu, H., 2019, In: IUCrJ. 6, p. 331-340 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • X ray lasers 100%
  • Free electron lasers 85%
  • Single Molecule Imaging 75%
  • Free Electron 70%
  • free electron lasers 56%
  19 Scopus citations

• Forward model for propagation-based X-ray phase contrast imaging in parallel- and conebeam geometry

  Shanblatt, E. R., Sung, Y., Gupta, R., Nelson, B. J., Leng, S., Graves, W. S. & McCollough, C. H., 2019, In: Optics Express. 27, 4, p. 4504-4521 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • phase contrast 100%
  • X-Rays 69%
  • propagation 52%
  • geometry 50%
  • x rays 40%
  7 Scopus citations

• Membrane directed expression in Escherichia coli of BBA57 and other virulence factors from the Lyme disease agent Borrelia burgdorferi

  Robertson, K. E., Truong, C. D., Craciunescu, F. M., Chiu, P. L., Fromme, P. & Hansen, D. T., Dec 1 2019, In: Scientific reports. 9, 1, 17606.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Borrelia burgdorferi 100%
  • Lyme Disease 95%
  • Virulence Factors 81%
  • Escherichia coli 55%
  • Protein Sorting Signals 50%
  4 Scopus citations

• Microcrystal electron diffraction methodology and applications

  Nannenga, B. L. & Gonen, T., Dec 1 2019, In: MRS Bulletin. 44, 12, p. 956-960 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Microcrystals 100%
  • Electron diffraction 74%
  • microcrystals 69%
  • Electron Diffraction 57%
  • electron diffraction 48%
  2 Scopus citations

• Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency

  Yun, J. H., Li, X., Park, J. H., Wang, Y., Ohki, M., Jin, Z., Lee, W., Park, S. Y., Hu, H., Li, C., Zatsepin, N., Hunter, M. S., Sierra, R. G., Koralek, J., Yoon, C. H., Cho, H. S., Weierstall, U., Tang, L., Liu, H. & Lee, W., Jan 18 2019, In: Journal of Biological Chemistry. 294, 3, p. 794-804 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Free Electron 100%
  • Chlorides 83%
  • Pump 75%
  • Temperature 56%
  • Rhodopsin 55%
  11 Scopus citations

• Protein-facilitated gold nanoparticle formation as indicators of ionizing radiation

  Thaker, A., Pushpavanam, K., Bista, T., Sapareto, S., Rege, K. & Nannenga, B. L., Dec 1 2019, In: Biotechnology and bioengineering. 116, 12, p. 3160-3167 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gold nanoparticles 100%
  • Ionizing radiation 89%
  • Ionizing Radiation 77%
  • Nanosensors 67%
  • Gold 64%
  5 Scopus citations