CLAS: Magnetic Resonance Research Center

Equipment/facility: Facility

  • Location

    United States

Description

The Magnetic Resonance Research Center at ASU (MRRC) is the regional southwest resource for characterization and structure determination of proteins, DNA, Biomolecules, chemical compounds, and solid materials by Nuclear Magnetic Resonance (NMR). This world-class facility has 800 and 500 MHz NMR spectrometers optimized for protein, biopolymer and DNA structure studies, two 400 MHz spectrometers for routine synthetic and drug design applications, and 300 and 400 MHz wide-bore systems for solid state NMR, diffusion and exotic NMR experiments. The 800 MHz instrument has dual solids/liquids capabilities, including the first Ultra-Fast Magic-Angle Spinning probe and BioMAS probe at 800 MHz. The center also has unique Magnetic Resonance Imaging (MRI) capabilities. The 800 MHz instrument has been equipped with a 12 mm MRI probe with 300 G/cm imaging gradients. The ultra high magnetic field (18.8 T) provides large gains in sensitivity and resolution for imaging and localized spectroscopy, facilitating a level of detail not accessible with lower field instruments. The MRRC has over 20 high-performance UNIX/Linux/Windows/Mac-based graphics workstations available for instrument control and data analysis. The workstations are equipped with a wide variety of software for processing and analysis of NMR spectra, solids simulation, protein and DNA structure determination, imaging, and molecular modeling and dynamics. Furthermore, the MRRC houses a self-contained laboratory for protein expression and characterization. The center also provides a dedicated teaching facility, including a 400 MHz spectrometer, printer, server, workstations and presentation equipment. The MRRC, formerly known as the ASU Nuclear Magnetic Resonance Facility, is located in a 5,500 sq. ft. laboratory in the basement of the new Interdisciplinary Science and Technology building I (ISTB-I, Room L2-63). The MRRC supports collaborative research and training in NMR/MRI across disciplines, and provides a special emphasis for support of projects at the interfaces of molecular medicine, bio-engineering, bio-inspired chemistry and physics, and materials research. The MRRC is designed to expand with the growing needs for NMR/MRI research capabilities, not only within ASU, but from regional research institutions as well. Training capabilities are also expanding with the recent revitalization of resources in the teaching laboratory, located in room H-530 of the Bateman Physical Science Complex.

-Bruker 400 MHz NMR
-Bruker Avance III HD 600 MHz NMR
-Bruker Avance III HD 850 MHz NMR
-Consultation/technical assistance
-MR 400 MHz NMR (walk-up)
-VNMRS 400 MHz WB NMR
-VNMRS 500 MHz WB NMR
-VNMRS 800 MHz 24 Hours
-VNMRS 800 MHz NMR



Contact: Brian Cherry

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Magnetic resonance
Nuclear magnetic resonance
Imaging techniques
Spectrometers
DNA
Teaching
Proteins
Magnetic resonance spectrometers
Printers (computer)
UNIX
Biopolymers
Magic angle spinning
Chemical compounds
Molecular modeling
Computer workstations
Biomolecules
Medicine
Molecular dynamics
Servers
Physics