Additional file 1: of Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice

  • Jordan Yaron (Creator)
  • Hao Chen (Creator)
  • Sriram Ambadapadi (Contributor)
  • Liqiang Zhang (Contributor)
  • Amanda M. Tafoya (Creator)
  • Barbara H. Munk (Creator)
  • Dara Wakefield (Creator)
  • Jorge Fuentes (Creator)
  • Bruno J. Marques (Creator)
  • Krishna Harripersaud (Creator)
  • Mee Y. Bartee (Creator)
  • Jennifer A. Davids (Creator)
  • Donghang Zheng (Contributor)
  • Ken Rand (Creator)
  • Lisa Dixon (Creator)
  • R. W. Moyer (Creator)
  • William Clapp (Creator)
  • Alexandra Lucas (Creator)

Dataset

Description

Figure S1. Serp-2 mediated protection against LIRI at 24 hours does not prevent cleavage of caspases 1, 3 and 8. (a) Immunoblot analysis of 2 mice each from sham surgery or from 90 minutes liver ischemia-reperfusion injury at 24 hours follow-up probed for antibodies against cleaved caspase-3 (p19), full length/cleaved caspase-8 (p45/p18) and full length/cleaved caspase-1 (p45/p20) with actin as a loading control. (b) Densitometry of cleaved bands for caspases-1, -3 and -8 normalized to actin. Statistics performed by 2-Way ANOVA with Fisherâ s LSD. (TIF 361 kb)
Date made available2019
Publisherfigshare Academic Research System

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