Description
Experimental Technique/Method:X-RAY DIFFRACTION
Resolution:3.0
Classification:SIGNALING PROTEIN
Release Date:2017-07-26
Deposition Date:2016-11-05
Revision Date:2017-08-16#2017-09-13#2018-02-14
Molecular Weight:201427.98
Macromolecule Type:Protein
Residue Count:1812
Atom Site Count:12395
DOI:10.2210/pdb5tud/pdb
Abstract:
Monoclonal antibodies provide an attractive alternative to small-molecule therapies for a wide range of diseases. Given the importance of G protein-coupled receptors (GPCRs) as pharmaceutical targets, there has been an immense interest in developing therapeutic monoclonal antibodies that act on GPCRs. Here we present the 3.0-Å resolution structure of a complex between the human 5-hydroxytryptamine 2B (5-HT
Resolution:3.0
Classification:SIGNALING PROTEIN
Release Date:2017-07-26
Deposition Date:2016-11-05
Revision Date:2017-08-16#2017-09-13#2018-02-14
Molecular Weight:201427.98
Macromolecule Type:Protein
Residue Count:1812
Atom Site Count:12395
DOI:10.2210/pdb5tud/pdb
Abstract:
Monoclonal antibodies provide an attractive alternative to small-molecule therapies for a wide range of diseases. Given the importance of G protein-coupled receptors (GPCRs) as pharmaceutical targets, there has been an immense interest in developing therapeutic monoclonal antibodies that act on GPCRs. Here we present the 3.0-Å resolution structure of a complex between the human 5-hydroxytryptamine 2B (5-HT
Date made available | 2017 |
---|---|
Publisher | RCSB-PDB |